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  1. Book ; Online ; E-Book: Ketogenic diet and metabolic therapies

    Masino, Susan

    expanded roles in health and disease

    2022  

    Abstract: Ketogenic diets have been treating epilepsy for a century. Finally - no need to say "nearly" 100 years since it was published in 1921! To many it feels like a long time, yet we are still at the beginning. It has taken many decades to begin to appreciate ...

    Author's details edited by Susan A. Masino
    Abstract "Ketogenic diets have been treating epilepsy for a century. Finally - no need to say "nearly" 100 years since it was published in 1921! To many it feels like a long time, yet we are still at the beginning. It has taken many decades to begin to appreciate the potential of ketogenic diet and metabolic therapies in health and disease. Thankfully, good ideas persist. They can and must be revisited and retested"--
    Keywords Diet, Ketogenic ; Metabolism / physiology ; Metabolic Diseases / diet therapy
    Subject code 613.2/833
    Language English
    Size 1 Online-Ressource (x, 566 Seiten), Illustrationen, Diagramme
    Edition Second edition
    Publisher Oxford University Press
    Publishing place New York, NY
    Publishing country United States
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021288019
    ISBN 978-0-19-750122-1 ; 978-0-19-750123-8 ; 9780197501207 ; 0-19-750122-2 ; 0-19-750123-0 ; 0197501206
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book: Ketogenic diet and metabolic therapies

    Masino, Susan

    expanded roles in health and disease

    2017  

    Author's details edited by Susan A. Masino, PHD
    Keywords Ketogenic Diet ; Metabolism / physiology
    Language English
    Size XV, 408 Seiten, Illustrationen, Diagramme
    Publisher Oxford University Press
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT019237996
    ISBN 978-0-19-049799-6 ; 0-19-049799-8
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2017 A 403 available for loan (reading room) Lesesaal EG

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  3. Book: Adenosine

    Masino, Susan / Boison, Detlev

    a key link between metabolism and brain activity

    2012  

    Author's details Susan Masino ; Detlev Boison ed
    Keywords Adenosine--Therapeutic use. ; Adenosine--Physiological effect ; Nucleosides--Therapeutic use.
    Language English
    Size XVI, 679 S. : Ill., graph. Darst., 26 cm
    Publisher Springer
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT017400330
    ISBN 978-1-4614-3902-8 ; 1-4614-3902-7 ; 9781461439035 ; 1461439035
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2012 A 3842 order for loan Magazin

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  4. Book ; Online ; E-Book: Homeostatic control of brain function

    Boison, Detlev / Masino, Susan A.

    2016  

    Author's details edited by Detlev Boison, PhD; Susan A. Masono
    Keywords Homeostasis / physiology ; Brain / physiology ; Brain Chemistry
    Language English
    Size 1 Online-Ressource (xiv, 642 Seiten), Illustrationen
    Publisher Oxford University Press
    Publishing place Oxford
    Publishing country United States
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019008801
    ISBN 978-0-199-32230-5 ; 9780199322299 ; 0-199-32230-9 ; 0199322295
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

    Full text online

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  5. Book ; Online: Metabolic Control of Brain Homeostasis

    Meier, Jochen C. / Boison, Detlev / Masino, Susan A.

    2017  

    Abstract: Brain function is under metabolic control, which in turn determines the equilibrium of homeostatic systems that affect neuronal and glial networks on the molecular, cellular, and systems levels. The collection of articles ranges from molecules and ... ...

    Abstract Brain function is under metabolic control, which in turn determines the equilibrium of homeostatic systems that affect neuronal and glial networks on the molecular, cellular, and systems levels. The collection of articles ranges from molecules and mechanisms involved in regulating homeostasis and neuronal excitability to therapeutic mechanisms tailored to restore homeostatic function. It also features neurological diseases and novel treatment approaches that are based on metabolic and homeostatic interventions. Together, the collection of articles outlines novel strategies to restore brain function in neurology and highlights limitations of conventional pharmacological approaches. We suggest that restoration of molecular and biochemical networks could lead to a new era of therapeutic opportunities
    Keywords Science (General) ; Neurosciences. Biological psychiatry. Neuropsychiatry
    Size 1 electronic resource (204 p.)
    Publisher Frontiers Media SA
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020097425
    ISBN 9782889452866 ; 2889452867
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  6. Book: Ketogenic diet and metabolic therapies

    Masino, Susan

    expanded roles in health and disease

    2017  

    Author's details edited by Susan A. Masino ; section editors, Detlev Boison, Dominic P. D'Agostino, Eric H. Kossoff, Jong M. Rho
    MeSH term(s) Ketogenic Diet ; Metabolism/physiology
    Language English
    Size xv, 408 pages :, illustrations
    Document type Book
    ISBN 9780190497996 ; 0190497998
    Database Catalogue of the US National Library of Medicine (NLM)

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  7. Article ; Online: Metabolism and epilepsy: Ketogenic diets as a homeostatic link.

    Masino, Susan A / Rho, Jong M

    Brain research

    2018  Volume 1703, Page(s) 26–30

    Abstract: Metabolic dysfunction can underlie seizure disorders, and metabolism-based treatments can afford seizure control and promote homeostasis. This relationship between metabolism and the risk of sporadic seizures was observed historically with the clinical ... ...

    Abstract Metabolic dysfunction can underlie seizure disorders, and metabolism-based treatments can afford seizure control and promote homeostasis. This relationship between metabolism and the risk of sporadic seizures was observed historically with the clinical success of a low-carbohydrate, high-fat, ketosis-inducing ketogenic diet - a treatment that remains relevant today, and one that has been shown to be effective against medically refractory epilepsy. Mechanisms underlying the success of the ketogenic diet are a topic of intense research efforts - not only because of proven success in arresting treatment-resistant seizures, but also because recent evidence suggests that altering metabolism with a ketogenic diet enables a homeostatic state in the brain that is less excitable, and hence raises the threshold for seizure genesis. Metabolic therapy with a ketogenic diet has been shown to normalize a range of abnormal physiological and behavioral parameters and may also make the central nervous system more resilient to other insults or physiological stresses. Because the therapeutic ability of such a diet may be more limited than a drug because of a dose "ceiling", investigations are underway to develop and test analogous or supplemental approaches. In addition, significant efforts have been made to demonstrate broader applications of metabolic therapy in promoting health and preventing disease, including conditions where epileptic seizures manifest in a comorbid fashion.
    MeSH term(s) Brain/metabolism ; Central Nervous System/metabolism ; Diet ; Diet, Ketogenic/methods ; Epilepsy/diet therapy ; Epilepsy/metabolism ; Homeostasis ; Humans ; Ketosis ; Seizures/diet therapy ; Seizures/metabolism
    Language English
    Publishing date 2018-06-06
    Publishing country Netherlands
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1200-2
    ISSN 1872-6240 ; 0006-8993
    ISSN (online) 1872-6240
    ISSN 0006-8993
    DOI 10.1016/j.brainres.2018.05.049
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 161: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Adenosine and Ketogenic Treatments.

    Ruskin, David N / Kawamura, Masahito / Masino, Susan A

    Journal of caffeine and adenosine research

    2020  Volume 10, Issue 3, Page(s) 104–109

    Abstract: It is well known that the neuromodulator adenosine, acting through the adenosine ... ...

    Abstract It is well known that the neuromodulator adenosine, acting through the adenosine A
    Language English
    Publishing date 2020-09-16
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2928613-X
    ISSN 2573-3400 ; 2573-3397
    ISSN (online) 2573-3400
    ISSN 2573-3397
    DOI 10.1089/caff.2020.0011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Ketogenic diet effects on inflammatory allodynia and ongoing pain in rodents.

    Ruskin, David N / Sturdevant, Isabella C / Wyss, Livia S / Masino, Susan A

    Scientific reports

    2021  Volume 11, Issue 1, Page(s) 725

    Abstract: Ketogenic diets are very low carbohydrate, high fat, moderate protein diets used to treat medication-resistant epilepsy. Growing evidence suggests that one of the ketogenic diet's main mechanisms of action is reducing inflammation. Here, we examined the ... ...

    Abstract Ketogenic diets are very low carbohydrate, high fat, moderate protein diets used to treat medication-resistant epilepsy. Growing evidence suggests that one of the ketogenic diet's main mechanisms of action is reducing inflammation. Here, we examined the diet's effects on experimental inflammatory pain in rodent models. Young adult rats and mice were placed on the ketogenic diet or maintained on control diet. After 3-4 weeks on their respective diets, complete Freund's adjuvant (CFA) was injected in one hindpaw to induce inflammation; the contralateral paw was used as the control. Tactile sensitivity (von Frey) and indicators of spontaneous pain were quantified before and after CFA injection. Ketogenic diet treatment significantly reduced tactile allodynia in both rats and mice, though with a species-specific time course. There was a strong trend to reduced spontaneous pain in rats but not mice. These data suggest that ketogenic diets or other ketogenic treatments might be useful treatments for conditions involving inflammatory pain.
    MeSH term(s) Animals ; Diet, Ketogenic/methods ; Disease Models, Animal ; Hyperalgesia/diet therapy ; Hyperalgesia/etiology ; Hyperalgesia/pathology ; Inflammation/complications ; Male ; Mice ; Mice, Inbred C57BL ; Pain/diet therapy ; Pain/etiology ; Pain/pathology ; Rats ; Rats, Sprague-Dawley
    Language English
    Publishing date 2021-01-12
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-020-80727-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book: Homeostatic control of brain function

    Boison, Detlev / Masino, Susan A

    2016  

    Author's details edited by Detlev Boison and Susan A. Masino
    MeSH term(s) Homeostasis/physiology ; Brain/physiology ; Brain Chemistry
    Language English
    Size xiv, 642 pages :, illustrations
    Document type Book
    ISBN 9780199322299 ; 0199322295
    Database Catalogue of the US National Library of Medicine (NLM)

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