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  1. Book ; Online ; Thesis: Konstruktion und Reliabilitätsprüfung eines neuen Schizotypie-Inventars shizotypal personality inventory (SPI)

    Maslehaty, Homajoun

    2007  

    Author's details vorgelegt von Homajoun Maslehaty
    Language German
    Publishing country Germany
    Document type Book ; Online ; Thesis
    Thesis / German Habilitation thesis Hamburg, Univ., Diss., 2007
    HBZ-ID HT015522931
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book: Neurostatus

    Maslehaty, Homajoun

    Anamnese, Untersuchung, Patientenvorstellung

    2009  

    Author's details Homajoun Maslehaty
    Keywords Nervensystem ; Krankheit ; Anamnese ; Befund ; Untersuchung
    Subject Erkrankung ; Krankheitszustand ; Krankheiten ; Morbus ; Nosos ; Pathos ; Systema nervosum ; NS ; Krankenuntersuchung ; Ärztliche Untersuchung ; Medizinische Untersuchung ; Ärztliche Untersuchungstechnik ; Klinische Untersuchung ; Körperliche Untersuchung ; Befunderhebung ; Medizinischer Befund ; Klinischer Befund ; Anamneseerhebung
    Subject code 616.80475
    Language German
    Size V, 93 S. : zahlr. Ill., 21 cm, 156 gr.
    Edition 1. Aufl.
    Publisher Shaker
    Publishing place Aachen
    Publishing country Germany
    Document type Book
    HBZ-ID HT016222197
    ISBN 978-3-8322-8448-0 ; 3-8322-8448-6
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2010 A 1285 order for loan Magazin

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  3. Book ; Online ; Thesis: Konstruktion und Reliabilitätsprüfung eines neuen Schizotypie-Inventars shizotypal personality inventory (SPI)

    Maslehaty, Homajoun

    2007  

    Author's details vorgelegt von Homajoun Maslehaty
    Language German
    Size Online-Ressource
    Publisher Staats- und Universitätsbibliothek Carl von Ossietzky
    Publishing place Hamburg
    Document type Book ; Online ; Thesis
    Thesis / German Habilitation thesis Univ., FB Medizin, Diss.--Hamburg, 2007
    Note Erscheinungsjahr an der Haupttitelstelle: 2006
    Database Former special subject collection: coastal and deep sea fishing

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  4. Article ; Online: Evaluation of the risk of rupture of intracranial aneurysms in patients with aneurysmal subarachnoid hemorrhage according to the PHASES score.

    Neyazi, Belal / Sandalcioglu, I Erol / Maslehaty, Homajoun

    Neurosurgical review

    2018  Volume 42, Issue 2, Page(s) 489–492

    Abstract: The PHASES score was developed to determine the risk of rupture of un-ruptured intracranial aneurysms (UIAs). The purposes of the current study were to apply this score on patients with actually ruptured intracranial aneurysms and to analyze the ... ...

    Abstract The PHASES score was developed to determine the risk of rupture of un-ruptured intracranial aneurysms (UIAs). The purposes of the current study were to apply this score on patients with actually ruptured intracranial aneurysms and to analyze the hypothetically prediction of the risk in this particularly patient group. We extracted the data of 100 recently treated patients (23 male, 77 female, mean age 56.4 years, range 17-93 years) with ruptured saccular intracranial aneurysms from our prospectively maintained neurovascular database according to the parameters used in the PHASES score (population, hypertension, age, earlier SAH, size and site of the aneurysm). Descriptive statistical analysis was performed using SPSS for Windows version 18.0 (SPSS Inc., Chicago, Illinois, USA). Ninety-nine percent of the patients were European and 1% Japanese in our series. Pre-existing arterial hypertension was found in 59%. Fifteen percent of the patients were > 75 years. Earlier SAH was found in 1%. The site of the aneurysms were the internal carotid artery (ICA) in 10%, the middle cerebral artery (MCA) in 14%, and arteries of the anterior and posterior circulation (PC) including the posterior communicating artery (PCOM) in 76%. Sixty-six percent of the aneurysms were smaller than 7 mm, 18% ranged between 7 and 9.9 mm, 14% were between 10 and 19.9 mm, and 2% were larger than 20 mm. European population, aneurysm size < 7 mm, and age < 75 years scored with 0 point in the PHASES study occurred most frequently in our series. The distribution of the aneurysm site to the anterior and posterior circulation scored with 4 points occurred most frequently. Considering the 5-year risk of rupture, 70% of our patient collective would have an estimated risk of < 2%. Interestingly, 70% of the patients with aneurysmal SAH had a low risk profile and would have a low risk of rupture according to the PHASES score in our series. This observation underlines the discrepancy of the estimated low risk of rupture for UIAs in young and healthy patients and the obvious fact the majority of the SAH patients are actually young with low risk factors. Parameters beyond the features of the PHASES score are needed to determine the risk of rupture of intracranial aneurysms.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Aneurysm, Ruptured/complications ; Carotid Artery, Internal ; Databases, Factual ; Female ; Humans ; Intracranial Aneurysm/complications ; Male ; Middle Aged ; Middle Cerebral Artery ; Risk Factors ; Subarachnoid Hemorrhage/etiology ; Young Adult
    Language English
    Publishing date 2018-06-11
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 6907-3
    ISSN 1437-2320 ; 0344-5607
    ISSN (online) 1437-2320
    ISSN 0344-5607
    DOI 10.1007/s10143-018-0989-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1445: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: The inferior frontal gyrus and cough.

    Maslehaty, Homajoun / Petridis, Athanasios K

    Clinics and practice

    2014  Volume 4, Issue 1, Page(s) 609

    Abstract: We present a case of a patient with a tumor close to the right inferior frontal gyrus. The only symptom this patient had was a disturbing dry cough. After removal of the tumor the cough disappeared immediately. Review of the literature showed that there ... ...

    Abstract We present a case of a patient with a tumor close to the right inferior frontal gyrus. The only symptom this patient had was a disturbing dry cough. After removal of the tumor the cough disappeared immediately. Review of the literature showed that there is a control center of voluntary cough in the right inferior frontal gyrus. Our case suggests that there might be such a center, which can be affected by a tumor close to it.
    Language English
    Publishing date 2014-03-27
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2605724-4
    ISSN 2039-7283 ; 2039-7275
    ISSN (online) 2039-7283
    ISSN 2039-7275
    DOI 10.4081/cp.2014.609
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Predictors of Brain Natriuretic Peptide Serum Level Elevation in Patients with Symptomatic Chronic Subdural Hematoma: A Prospective Study.

    Chihi, Mehdi / Jabbarli, Ramazan / Parlak, Ahmet / Darkwah-Oppong, Marvin / Gembruch, Oliver / Wrede, Karsten Henning / Sure, Ulrich / Maslehaty, Homajoun

    Journal of clinical medicine

    2021  Volume 10, Issue 8

    Abstract: Background: Brain natriuretic peptide serum levels (BNP) on admission are frequently elevated in patients with symptomatic chronic subdural hematoma (cSDH) and predict unfavorable long-term functional outcomes. However, the reasons for these elevated ... ...

    Abstract Background: Brain natriuretic peptide serum levels (BNP) on admission are frequently elevated in patients with symptomatic chronic subdural hematoma (cSDH) and predict unfavorable long-term functional outcomes. However, the reasons for these elevated levels remain unclear. Therefore, we aimed to identify the predictors of BNP elevation.
    Methods: Patients with unilateral symptomatic cSDH who were surgically treated in our department between November 2016 and May 2020 were enrolled. Patients' symptoms and neurological deficits were prospectively assessed using a study questionnaire. On initial computer tomography, hematoma volumes and midline shift (MLS) values were measured to analyze the degree of brain compression.
    Results: In total, 100 patients were analyzed. Linear regression analysis showed that higher BNP levels were significantly associated with smaller hematoma volumes (
    Conclusion: In symptomatic cSDH, BNP elevation is related, among others, to the presence of neurological deficits and smaller hematoma volumes. Whether BNP elevation may coincide with the early stage of hematoma growth, i.e., immaturity of cSDH neomembrane, requires further investigations.
    Language English
    Publishing date 2021-04-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm10081791
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Age-dependent changes of collagen alpha-2(IV) expression in the extracellular matrix of brain arteriovenous malformations.

    Neyazi, Belal / Stein, Klaus-Peter / Wilkens, Ludwig / Maslehaty, Homajoun / Dumitru, Claudia A / Sandalcioglu, I Erol

    Clinical neurology and neurosurgery

    2019  Volume 189, Page(s) 105589

    Abstract: Objectives: Brain arteriovenous malformations (bAVM) are rare vascular lesions. Recent observations challenge the congenital nature of these lesions. The underlying cellular and molecular mechanisms associated with dynamic changes of bAVM still remain ... ...

    Abstract Objectives: Brain arteriovenous malformations (bAVM) are rare vascular lesions. Recent observations challenge the congenital nature of these lesions. The underlying cellular and molecular mechanisms associated with dynamic changes of bAVM still remain unclear. The objective of this study was to explore the potential role of COL4A2 (Collagen alpha-2(IV)) in the pathophysiology of bAVM.
    Patients and methods: Expression and localization of COL4A2 were analyzed on tissue microarrays from bAVM patients (n = 60) by immunohistochemistry. Correlations between COL4A2 levels and clinical parameters were examined with Pearson's test for normally- distibuted or Spearman's Rho for not normally distributed data. Comparison between different clinical parameters was performed using t-test, non-parametric Mann-Whitney U test or Kruskal- Wallis test. Fisher's exact test was used for categorical data.
    Results: COL4A2 was mainly expressed beneath the endothelium of vessels in the tunica media of bAVM. This pattern of expression indicates the basement membrane of the vessel walls. High levels of COL4A2 expression correlated with the age at surgery of patients (p = 0.005; R = 0.393; Spearman's Rho). The age at surgery in young (17-25 years) and old patients (55-76 years) showed a linear correlation; a greater variance of COL4A2 expression was observed in the age group between 26-54 years.
    Conclusion: This study reports for the first time the expression of COL4A2 in bAVM and suggests a potential role of COL4A2 in bAVM pathophysiology. These findings contribute to a better understanding of the microenvironment of bAVM and may foster the development of improved therapeutic strategies for this disease.
    MeSH term(s) Adolescent ; Adult ; Age Factors ; Aged ; Aged, 80 and over ; Arteriovenous Fistula/metabolism ; Arteriovenous Fistula/surgery ; Basement Membrane/metabolism ; Blood Vessels/metabolism ; Brain Neoplasms/surgery ; Case-Control Studies ; Child ; Collagen Type IV/metabolism ; Endothelium/metabolism ; Extracellular Matrix/metabolism ; Female ; Glioma/surgery ; Humans ; Immunohistochemistry ; Intracranial Arteriovenous Malformations/metabolism ; Intracranial Arteriovenous Malformations/surgery ; Male ; Middle Aged ; Tissue Array Analysis ; Tunica Media/metabolism ; Young Adult
    Chemical Substances COL4A2 protein, human ; Collagen Type IV
    Language English
    Publishing date 2019-11-05
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 193107-6
    ISSN 1872-6968 ; 0303-8467
    ISSN (online) 1872-6968
    ISSN 0303-8467
    DOI 10.1016/j.clineuro.2019.105589
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    Ui I Zs.53: Show issues Location:
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  8. Article: Surgical Anatomy of the Orbit in Human Cadavers-An Endoscopic Pictorial Documentation.

    Maslehaty, Homajoun / Schultheiss, Saskia / Scholz, Martin / Petridis, Athanasios K

    Journal of neurological surgery. Part B, Skull base

    2017  Volume 79, Issue 2, Page(s) 173–176

    Abstract: ... ...

    Abstract Background
    Language English
    Publishing date 2017-08-28
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2654269-9
    ISSN 2193-634X ; 2193-6331
    ISSN (online) 2193-634X
    ISSN 2193-6331
    DOI 10.1055/s-0037-1606294
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3425: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  9. Article ; Online: Role of brain natriuretic peptide in the prediction of long-term surgical outcome of chronic subdural hematoma.

    Chihi, Mehdi / Gembruch, Oliver / Darkwah Oppong, Marvin / Rauschenbach, Laurèl / Rauscher, Steffen / Jabbarli, Ramazan / Wrede, Karsten H / Sure, Ulrich / Maslehaty, Homajoun

    Journal of the neurological sciences

    2020  Volume 420, Page(s) 117240

    Abstract: Objective: To investigate the role of brain natriuretic peptide (BNP) in predicting long-term functional outcome and develop a new predictive score of poor functional outcome after surgery for chronic subdural hematoma (cSDH).: Methods: Patients with ...

    Abstract Objective: To investigate the role of brain natriuretic peptide (BNP) in predicting long-term functional outcome and develop a new predictive score of poor functional outcome after surgery for chronic subdural hematoma (cSDH).
    Methods: Patients with cSDH that were surgically treated in our department between November 2016 and December 2019 were included in the study. Pre- and postoperative plasma BNP and clinical condition were prospectively recorded. At follow-up (5-6 months), a simplified modified Rankin Scale (mRS) questionnaire was conducted through a standardized telephone interview. A poor outcome was defined by a mRS > 3. Based on predictors of the long-term functional outcome, a score was calculated. Its accuracy was tested using the area under the curve (AUC) of the receiver operating characteristic analysis.
    Results: In total, 119 patients were analyzed (median age: 76 years, range: 44-94 years). Preoperative plasma BNP (BNP-1) was elevated in 77 patients (64.7%). For the follow-up phone interview, 101 patients (84.8%) were available. In the multivariate analysis, poor outcome at follow-up could be predicted using BNP-1 (p = 0.034), age (p = 0.036), motor deficit (p = 0.013) and Glasgow coma scale score on admission (p = 0.008). The "Functional Long-term Outcome Predictive score" (FLOP-score) was therefore computed, and revealed an excellent discriminative capacity compared to other scores, with an AUC of 0.86 (0.77-0.95).
    Conclusions: Preoperative plasma BNP is an independent predictor of functional outcome at follow-up. Using the FLOP-score, the risk of experiencing a poor outcome could accurately be predicted.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Hematoma, Subdural, Chronic/surgery ; Humans ; Middle Aged ; Natriuretic Peptide, Brain ; Postoperative Period ; ROC Curve ; Treatment Outcome
    Chemical Substances Natriuretic Peptide, Brain (114471-18-0)
    Language English
    Publishing date 2020-11-23
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 80160-4
    ISSN 1878-5883 ; 0022-510X ; 0374-8642
    ISSN (online) 1878-5883
    ISSN 0022-510X ; 0374-8642
    DOI 10.1016/j.jns.2020.117240
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    Zs.A 308: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  10. Article ; Online: Analysis of Brain Natriuretic Peptide Serum Levels in Patients with Symptomatic Chronic Subdural Hematoma: A Potential Reliable Biomarker.

    Chihi, Mehdi / Gembruch, Oliver / Darkwah Oppong, Marvin / Helsper, Moritz / Hütter, Bernd-Otto / Jabbarli, Ramazan / Wrede, Karsten H / Sure, Ulrich / Maslehaty, Homajoun

    Journal of neurotrauma

    2020  Volume 37, Issue 20, Page(s) 2211–2218

    Abstract: The purpose of this study was to analyze brain natriuretic peptide (BNP) serum levels of patients with chronic subdural hematoma (cSDH) and their clinical implication. Patients with cSDH who underwent surgery in our department between November 2016 and ... ...

    Abstract The purpose of this study was to analyze brain natriuretic peptide (BNP) serum levels of patients with chronic subdural hematoma (cSDH) and their clinical implication. Patients with cSDH who underwent surgery in our department between November 2016 and October 2019 were eligible for enrollment in the study. Patients with recurrent bleedings, traumatic brain injury, cSDH associated with other intracranial pathologies, and those with a history of congestive heart failure, renal or endocrine disease were excluded. We measured BNP serum levels pre- and post-operatively and at discharge. The BNP values were analyzed with respect to patient medical history and neurological condition. The Glasgow Coma Scale score and the modified Rankin Scale score classified the clinical and neurological condition at the time of admission and discharge, respectively. The data of 100 surgically treated patients with cSDH (mean age 73.2, range 42 - 94 years, male/female 3.5:1) were analyzed. Pre-operative BNP serum levels (BNP-1) were elevated in 67% of the patients (
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Biomarkers/blood ; Female ; Hematoma, Subdural, Chronic/blood ; Humans ; Male ; Middle Aged ; Natriuretic Peptide, Brain/blood
    Chemical Substances Biomarkers ; Natriuretic Peptide, Brain (114471-18-0)
    Language English
    Publishing date 2020-06-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645092-1
    ISSN 1557-9042 ; 0897-7151
    ISSN (online) 1557-9042
    ISSN 0897-7151
    DOI 10.1089/neu.2020.7110
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