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  1. Article ; Online: Combined lactic acidosis and ketoacidosis in a female diabetic patient with severe heart failure.

    Nzomessi, Desire / Massie, Emmanuelle / Gariani, Karim / Giraud, Raphael / Meyer, Philippe

    Cardiovascular endocrinology & metabolism

    2023  Volume 12, Issue 3, Page(s) e0287

    Abstract: SGLT2i are now recommended in a wide spectrum of indications including type 2 diabetes (T2DM), heart failure, and chronic kidney disease. This medication class is now available in combination with metformin, which is still a fundamental treatment in ... ...

    Abstract SGLT2i are now recommended in a wide spectrum of indications including type 2 diabetes (T2DM), heart failure, and chronic kidney disease. This medication class is now available in combination with metformin, which is still a fundamental treatment in patients with T2DM. Despite excellent proven safety profile for both drugs, the expanding use of these agents in clinical practice may lead to an increased incidence of rare side effects, like metformin-associated lactic acidosis (MALA) and euglycemic diabetic ketoacidosis (EDKA), which can be life-threatening. A 58-year-old woman with T2DM and severe heart failure treated by metformin and empagliflozin developed progressive EDKA triggered by fasting that was also complicated by severe acute renal failure and MALA. She was successfully treated with intermittent hemodialysis. This case report highlights the importance of the recognition of rare, but very serious adverse effects due to combined metformin and SGLT2i therapy.
    Language English
    Publishing date 2023-07-04
    Publishing country United States
    Document type Case Reports
    ISSN 2574-0954
    ISSN (online) 2574-0954
    DOI 10.1097/XCE.0000000000000287
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Cardiomyopathy and Cardiogenic Shock Caused by Juvenile Hemochromatosis Improving With Guideline-Directed Medical Therapy Despite High Ferritin Levels.

    Dessureault, Alexandre / Massie, Emmanuelle / Fish, Douglas / Parent, Marie-Claude

    The Canadian journal of cardiology

    2023  Volume 40, Issue 4, Page(s) 662–663

    MeSH term(s) Humans ; Shock, Cardiogenic/diagnosis ; Shock, Cardiogenic/drug therapy ; Shock, Cardiogenic/etiology ; Hemochromatosis/complications ; Hemochromatosis/diagnosis ; Hemochromatosis/congenital ; Cardiomyopathies/complications ; Ferritins
    Chemical Substances Ferritins (9007-73-2)
    Language English
    Publishing date 2023-11-18
    Publishing country England
    Document type Case Reports
    ZDB-ID 632813-1
    ISSN 1916-7075 ; 0828-282X
    ISSN (online) 1916-7075
    ISSN 0828-282X
    DOI 10.1016/j.cjca.2023.11.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2150: Show issues Location:
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  3. Article ; Online: A Silent Arrhythmia: How Would You Manage This Patient?

    Boulet, Jacinthe / Massie, Emmanuelle / Liszkowski, Mark

    Circulation

    2021  Volume 143, Issue 22, Page(s) 2205–2207

    MeSH term(s) Arrhythmias, Cardiac/diagnosis ; Electrocardiography/methods ; Humans ; Male ; Middle Aged
    Language English
    Publishing date 2021-06-01
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 80099-5
    ISSN 1524-4539 ; 0009-7322 ; 0069-4193 ; 0065-8499
    ISSN (online) 1524-4539
    ISSN 0009-7322 ; 0069-4193 ; 0065-8499
    DOI 10.1161/CIRCULATIONAHA.121.054894
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  4. Article ; Online: Heart Failure With Midrange Ejection Fraction-What Is It, If Anything?

    Boulet, Jacinthe / Massie, Emmanuelle / Rouleau, Jean-Lucien

    The Canadian journal of cardiology

    2020  Volume 37, Issue 4, Page(s) 585–594

    Abstract: The patient cohort with left ventricular ejection fractions (LVEFs) of 41%-49%, which has been defined as heart failure with midrange ejection fraction (HFmrEF), represent a significant proportion of the heart failure (HF) population. Despite the clear ... ...

    Abstract The patient cohort with left ventricular ejection fractions (LVEFs) of 41%-49%, which has been defined as heart failure with midrange ejection fraction (HFmrEF), represent a significant proportion of the heart failure (HF) population. Despite the clear cutoffs established by different society guidelines, confusion remains regarding the exact significance of midrange LVEF within the HF syndrome. Patients with LVEF 41%-49% represent a heterogeneous group of patients sharing pathophysiologic mechanisms, biomarker profiles, comorbidities, and clinical characteristics with patients with preserved and reduced LVEF. In this clinical review, we discuss the underlying pathophysiologic mechanisms that culminate in the clinical syndrome of HF and contribute to the disparities observed between HFpEF, HFrEF, and HFmrEF. We highlight differences and similarities in clinical characteristics and imaging features between HFpEF and HFrEF in an effort to disentangle the heterogeneous group of patients with midrange LVEF, but ultimately we conclude that LVEF should be seen as simply one important element of a continuum throughout the HF syndrome, and that although is useful, it is an oversimplification, because HF syndrome is more of a continuum. The underlying pathophysiology, etiology, and comorbidities of patients presenting with HF is becoming ever more important as the limitations of a classification solely based on LVEF are being better recognised, and as patient-specific personalisation of care is becoming ever more important.
    Language English
    Publishing date 2020-12-02
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 632813-1
    ISSN 1916-7075 ; 0828-282X
    ISSN (online) 1916-7075
    ISSN 0828-282X
    DOI 10.1016/j.cjca.2020.11.013
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  5. Article: Cardiac arrhythmias complicating total pneumonectomy.

    MASSIE, E / VALLE, A R

    Annals of internal medicine

    2010  Volume 26, Issue 2, Page(s) 231–239

    MeSH term(s) Arrhythmias, Cardiac ; Humans ; Lung/surgery ; Pneumonectomy
    Language English
    Publishing date 2010-01-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 336-0
    ISSN 1539-3704 ; 0003-4819
    ISSN (online) 1539-3704
    ISSN 0003-4819
    DOI 10.7326/0003-4819-26-2-231
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  6. Article: Palpitation.

    MASSIE, E / WIEGAND, H C

    The Journal of laboratory and clinical medicine

    2008  Volume 33, Issue 11, Page(s) 1487

    MeSH term(s) Arrhythmias, Cardiac ; Brugada Syndrome ; Cardiac Conduction System Disease ; Heart Conduction System ; Heart Rate ; Humans
    Language English
    Publishing date 2008-10-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80208-6
    ISSN 1532-6543 ; 0022-2143
    ISSN (online) 1532-6543
    ISSN 0022-2143
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  7. Article: Relative Value of Heated Toxin and Toxoid as Controls in the Schick Test.

    Loeffel, E / Massie, E

    American journal of public health and the nation's health

    2007  Volume 25, Issue 9, Page(s) 1018–1022

    Language English
    Publishing date 2007-10-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 121100-6
    ISSN 1541-0048 ; 0002-9572 ; 0090-0036
    ISSN (online) 1541-0048
    ISSN 0002-9572 ; 0090-0036
    DOI 10.2105/ajph.25.9.1018
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    Un I Zs.279: Show issues Location:
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  8. Article ; Online: Palpitations Revealing a Primary Pulmonary Artery Sarcoma.

    Massie, Emmanuelle / White, Michel / Robillard, Julie / Demers, Philippe / Mondésert, Blandine / Doyon, Josée / Chaix, Marie-A

    CJC open

    2021  Volume 3, Issue 6, Page(s) 831–834

    Abstract: Primary pulmonary artery sarcoma is an exceedingly rare and aggressive malignancy that carries poor prognosis. Clinical manifestations are nonspecific and include chest pain, dyspnea, syncope, palpitations, and asthenia, among others. Delay to diagnosis ... ...

    Abstract Primary pulmonary artery sarcoma is an exceedingly rare and aggressive malignancy that carries poor prognosis. Clinical manifestations are nonspecific and include chest pain, dyspnea, syncope, palpitations, and asthenia, among others. Delay to diagnosis is common and compromises the prognosis. Here, we report an interesting case of primary pulmonary artery sarcoma presenting with frequent monomorphic premature ventricular contractions arising from the right/left ventricle outflow tract. Cardiac imaging is key in the evaluation of patients with frequent premature ventricular contractions to rule out rare pathologies such as tumour compression.
    Language English
    Publishing date 2021-02-04
    Publishing country United States
    Document type Case Reports
    ISSN 2589-790X
    ISSN (online) 2589-790X
    DOI 10.1016/j.cjco.2021.01.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Current Review of Implantable Cardioverter Defibrillator Use in Patients With Left Ventricular Assist Device.

    Boulet, Jacinthe / Massie, Emmanuelle / Mondésert, Blandine / Lamarche, Yoan / Carrier, Michel / Ducharme, Anique

    Current heart failure reports

    2019  Volume 16, Issue 6, Page(s) 229–239

    Abstract: Purpose of review: While use of implantable cardioverter defibrillator (ICD) in patients with heart failure (HF) and reduced ejection fraction is recommended, their role in patients with left ventricular assist device (LVAD) remains controversial, ... ...

    Abstract Purpose of review: While use of implantable cardioverter defibrillator (ICD) in patients with heart failure (HF) and reduced ejection fraction is recommended, their role in patients with left ventricular assist device (LVAD) remains controversial, especially with continuous flow (CF) devices.
    Recent findings: Ventricular arrhythmias (VA) in LVAD patients are frequent and associated with worse outcomes, especially postoperatively. Data on the role of ICDs in LVAD patients are scarce, based on case reports or small retrospective series. While the majority of LVAD patients currently have an ICD, it seems that some might not derive any benefit, with additional risks in terms of inappropriate shocks, psychological distress, and infections. Some CF-LVAD patients are at high risk of VA and hemodynamic collapse; under those circumstances, an ICD might provide benefits. A randomized-controlled trial of routine ICD implantation in CF-LVAD would be needed to clarify their impact on survival in low risk patients.
    MeSH term(s) Arrhythmias, Cardiac/etiology ; Arrhythmias, Cardiac/therapy ; Defibrillators, Implantable/adverse effects ; Equipment Design ; Heart Failure/surgery ; Heart-Assist Devices/adverse effects ; Humans ; Risk Factors
    Language English
    Publishing date 2019-11-25
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2151202-4
    ISSN 1546-9549 ; 1546-9530
    ISSN (online) 1546-9549
    ISSN 1546-9530
    DOI 10.1007/s11897-019-00449-8
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  10. Article: Agranulocytosis due to propylthiouracil.

    FUTCHER, P H / MASSIE, E

    Annals of internal medicine

    2004  Volume 32, Issue 1, Page(s) 137

    MeSH term(s) Agranulocytosis ; Humans ; Propylthiouracil ; Thiourea
    Chemical Substances Propylthiouracil (721M9407IY) ; Thiourea (GYV9AM2QAG)
    Language English
    Publishing date 2004-09-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 336-0
    ISSN 1539-3704 ; 0003-4819
    ISSN (online) 1539-3704
    ISSN 0003-4819
    DOI 10.7326/0003-4819-32-1-137
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