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  1. Article ; Online: Concerns About a Dog Model of Dry Eye Disease.

    Ofri, Ron / Millichamp, Nicholas J / Keller, Charlotte / McLellan, Gillian J / Komáromy, András M / Morton, David / Matas, Màrian / Michau, Tammy M / Coall, Sarah / Sansom, Jane / Leonard, Brian C

    Translational vision science & technology

    2024  Volume 13, Issue 3, Page(s) 28

    MeSH term(s) Animals ; Dogs ; Dry Eye Syndromes/diagnosis ; Tears
    Language English
    Publishing date 2024-03-28
    Publishing country United States
    Document type Letter
    ZDB-ID 2674602-5
    ISSN 2164-2591 ; 2164-2591
    ISSN (online) 2164-2591
    ISSN 2164-2591
    DOI 10.1167/tvst.13.3.28
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Intracorneal hemorrhage in 19 dogs (22 eyes) from 2000 to 2010: a retrospective study.

    Matas, Màrian / Donaldson, David / Newton, Richard J

    Veterinary ophthalmology

    2012  Volume 15, Issue 2, Page(s) 86–91

    Abstract: Objective: The aim of this retrospective study is to review clinical data on patients that suffered intracorneal hemorrhage (ICH), and the veterinary and human literature available for this condition.: Animal studied: A search for ICH was performed ... ...

    Abstract Objective: The aim of this retrospective study is to review clinical data on patients that suffered intracorneal hemorrhage (ICH), and the veterinary and human literature available for this condition.
    Animal studied: A search for ICH was performed within the clinical database of the Animal Health Trust. Nineteen cases were identified (22 eyes).
    Procedures: The patient's age, breed, and gender were reviewed, together with etiology, location, treatment, and follow-up. The relevant data were compared with the Animal Health Trust (AHT) ophthalmology referral population for the same period of time (n=5555).
    Results: Twenty-two eyes were affected. No breed or sex predisposition could be identified. Patients aged 10 years and above were more frequently affected when compared with the AHT ophthalmology referral population. ICH was recorded in all corneal quadrants, with the mid-peripheral cornea more often affected. Areas of corneas affected by the ICH showed long-term loss of transparency. Ocular diseases as a source of neovascularization varied from ocular surface to intraocular disease. Systemic diseases were investigated in some patients, and no concomitant disease could be linked to the development of ICH.
    Conclusions: Intracorneal hemorrhage is a rare condition associated with corneal neovasculature. As in the human ophthalmology literature, ICH could not be linked to a specific ocular or systemic disease. Severe complications described in humans with this condition, such as pupillary block or corneal perforation, were not seen in any of these canine patients. Canine ICH seem to reabsorb with time, with or without medical treatment. Surgical treatment was not required in any of our patients.
    MeSH term(s) Animals ; Corneal Neovascularization/complications ; Corneal Neovascularization/veterinary ; Dog Diseases/etiology ; Dog Diseases/pathology ; Dogs ; Eye Diseases/etiology ; Eye Diseases/pathology ; Eye Diseases/veterinary ; Eye Hemorrhage/etiology ; Eye Hemorrhage/pathology ; Eye Hemorrhage/veterinary ; Female ; Male ; Retrospective Studies
    Language English
    Publishing date 2012-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2011043-1
    ISSN 1463-5224 ; 1463-5216
    ISSN (online) 1463-5224
    ISSN 1463-5216
    DOI 10.1111/j.1463-5224.2011.00944.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Intracorneal hemorrhage in 19 dogs (22 eyes) from 2000 to 2010: a retrospective study

    Matas, Màrian / Donaldson, David / Newton, Richard J

    Veterinary ophthalmology. 2012 Mar., v. 15, no. 2

    2012  

    Abstract: Objective The aim of this retrospective study is to review clinical data on patients that suffered intracorneal hemorrhage (ICH), and the veterinary and human literature available for this condition. Animal Studied A search for ICH was performed within ... ...

    Abstract Objective The aim of this retrospective study is to review clinical data on patients that suffered intracorneal hemorrhage (ICH), and the veterinary and human literature available for this condition. Animal Studied A search for ICH was performed within the clinical database of the Animal Health Trust. Nineteen cases were identified (22 eyes). Procedures The patient’s age, breed, and gender were reviewed, together with etiology, location, treatment, and follow‐up. The relevant data were compared with the Animal Health Trust (AHT) ophthalmology referral population for the same period of time (n = 5555). Results Twenty‐two eyes were affected. No breed or sex predisposition could be identified. Patients aged 10 years and above were more frequently affected when compared with the AHT ophthalmology referral population. ICH was recorded in all corneal quadrants, with the mid‐peripheral cornea more often affected. Areas of corneas affected by the ICH showed long‐term loss of transparency. Ocular diseases as a source of neovascularization varied from ocular surface to intraocular disease. Systemic diseases were investigated in some patients, and no concomitant disease could be linked to the development of ICH. Conclusions Intracorneal hemorrhage is a rare condition associated with corneal neovasculature. As in the human ophthalmology literature, ICH could not be linked to a specific ocular or systemic disease. Severe complications described in humans with this condition, such as pupillary block or corneal perforation, were not seen in any of these canine patients. Canine ICH seem to reabsorb with time, with or without medical treatment. Surgical treatment was not required in any of our patients.
    Keywords angiogenesis ; animal health ; breeds ; clinical trials ; cornea ; databases ; dogs ; etiology ; gender ; hemorrhage ; humans ; medical treatment ; ophthalmology ; patients ; retrospective studies ; surgery
    Language English
    Dates of publication 2012-03
    Size p. 86-91.
    Publishing place Blackwell Publishing Ltd
    Document type Article
    ZDB-ID 2011043-1
    ISSN 1463-5224 ; 1463-5216
    ISSN (online) 1463-5224
    ISSN 1463-5216
    DOI 10.1111/j.1463-5224.2011.00944.x
    Database NAL-Catalogue (AGRICOLA)

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  4. Article: Unilateral eyelid lesion and ophthalmologic findings in an aardvark (Orycteropus afer): case report and literature review

    Matas, Màrian / Wise, Innes / Masters, Nicholas J / Stewart, Jennifer / Holloway, Andrew / Donaldson, David / Hartley, Claudia

    Veterinary ophthalmology. 2010 Sept., v. 13, no. s1

    2010  

    Abstract: To summarize the medical knowledge surrounding aardvarks to date, to describe the ophthalmic examination of a specimen with a chronic history of an upper eyelid lesion, of an assumed blind left eye, and to detail the anesthesia procedure performed. A 23- ... ...

    Abstract To summarize the medical knowledge surrounding aardvarks to date, to describe the ophthalmic examination of a specimen with a chronic history of an upper eyelid lesion, of an assumed blind left eye, and to detail the anesthesia procedure performed. A 23-year-old aardvark was examined under general anesthesia and multiple ocular abnormalities were detected in the left eye (globe deviation, corneal opacities, iridodonesis, and aphakia). A thickening of the palpebral conjunctiva affecting the medial upper eyelid with erosion of the normal eyelid margin anatomy was identified. The adnexal lesion was resected by a wedge resection and histopathology was performed. Suture breakdown 3 days postoperatively required a second surgery, where buried sutures were used. The surgical techniques and postoperative care are discussed. The histopathology revealed mucosal hyperplasia and moderate neutrophilic and lymphoplasmacytic blepharitis. No causal organisms were identified. Following initial wound dehiscence and a modified surgical technique, the upper eyelid healed without complication and retained complete function. The eyelid lesion involved a benign inflammatory and hyperplastic pathology of unknown etiology. Adjusting routine ophthalmic surgical techniques to wildlife and zoo animals can be challenging and complicated. It is important to understand the nature of the animals being managed, their circadian cycle, and habitat, to adjust and individualize the surgical approach, instrumentation, suture material, and perioperative treatment.
    Keywords zoo animals ; eye diseases ; eyelids ; complications ; vision disorders ; case studies ; chronic diseases ; inflammation ; hyperplasia ; blindness ; histopathology ; anesthesia ; resection ; postoperative complications ; sutures ; Mammalia
    Language English
    Dates of publication 2010-09
    Size p. 116-122.
    Publisher Blackwell Publishing Ltd
    Publishing place Oxford, UK
    Document type Article
    ZDB-ID 2011043-1
    ISSN 1463-5224 ; 1463-5216
    ISSN (online) 1463-5224
    ISSN 1463-5216
    DOI 10.1111/j.1463-5224.2010.00803.x
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: Unilateral eyelid lesion and ophthalmologic findings in an aardvark (Orycteropus afer): case report and literature review.

    Matas, Màrian / Wise, Innes / Masters, Nicholas J / Stewart, Jennifer / Holloway, Andrew / Donaldson, David / Hartley, Claudia

    Veterinary ophthalmology

    2010  Volume 13 Suppl, Page(s) 116–122

    Abstract: Objective: To summarize the medical knowledge surrounding aardvarks to date, to describe the ophthalmic examination of a specimen with a chronic history of an upper eyelid lesion, of an assumed blind left eye, and to detail the anesthesia procedure ... ...

    Abstract Objective: To summarize the medical knowledge surrounding aardvarks to date, to describe the ophthalmic examination of a specimen with a chronic history of an upper eyelid lesion, of an assumed blind left eye, and to detail the anesthesia procedure performed.
    Procedure: A 23-year-old aardvark was examined under general anesthesia and multiple ocular abnormalities were detected in the left eye (globe deviation, corneal opacities, iridodonesis, and aphakia). A thickening of the palpebral conjunctiva affecting the medial upper eyelid with erosion of the normal eyelid margin anatomy was identified. The adnexal lesion was resected by a wedge resection and histopathology was performed. Suture breakdown 3 days postoperatively required a second surgery, where buried sutures were used. The surgical techniques and postoperative care are discussed.
    Results: The histopathology revealed mucosal hyperplasia and moderate neutrophilic and lymphoplasmacytic blepharitis. No causal organisms were identified. Following initial wound dehiscence and a modified surgical technique, the upper eyelid healed without complication and retained complete function.
    Conclusions: The eyelid lesion involved a benign inflammatory and hyperplastic pathology of unknown etiology. Adjusting routine ophthalmic surgical techniques to wildlife and zoo animals can be challenging and complicated. It is important to understand the nature of the animals being managed, their circadian cycle, and habitat, to adjust and individualize the surgical approach, instrumentation, suture material, and perioperative treatment.
    MeSH term(s) Animals ; Animals, Zoo ; Eyelid Diseases/pathology ; Eyelid Diseases/surgery ; Eyelid Diseases/veterinary ; Male ; Xenarthra
    Language English
    Publishing date 2010-09
    Publishing country England
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 2011043-1
    ISSN 1463-5224 ; 1463-5216
    ISSN (online) 1463-5224
    ISSN 1463-5216
    DOI 10.1111/j.1463-5224.2010.00803.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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