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Article ; Online: The ambulatory blood pressure monitoring among obese and nonobese diabetes mellitus patients.

Mathews, Hella Fiona / Kumar, Sunil / Madhu, B / Gona, Oliver Joel / Srinath, K M

Annals of African medicine

2022  Volume 21, Issue 3, Page(s) 255–261

Abstract: Background: Obesity and diabetes mellitus are two major factors related with the risk of metabolic syndrome and cardiovascular diseases. Co-existing hypertension with diabetes mellitus and obesity has poor prognosis for cardiovascular diseases. ... ...

Abstract Background: Obesity and diabetes mellitus are two major factors related with the risk of metabolic syndrome and cardiovascular diseases. Co-existing hypertension with diabetes mellitus and obesity has poor prognosis for cardiovascular diseases. Ambulatory blood pressure monitoring (ABPM) correlates more closely to target organ damage than clinic blood pressure.
Objectives: The objective of the study is to assess and compare ABPM pattern among obese and nonobese diabetes mellitus patients.
Materials and methods: A cross-sectional study was conducted among fifty obese and fifty nonobese diabetic patients who were classified based on their body mass index as per the WHO criterion. The clinical blood pressure measurements were measured on each subject using a digital sphygmomanometer, and 24 h ABPM was done and ABPM parameters such as dipping pattern, 24 h systolic blood pressure (SBP), diastolic blood pressure (DBP), Mean SBP, mean DBP, diurnal variability of SBP, DBP, Mean arterial pressure, pulse pressure, SD systole (Standard Deviation systole), SD diastole, white coat hypertension was derived and compared between the two groups.
Results: Around 37 (74%) obese and 18 (36%) nonobese showed non dipping pattern in SBP and 28 (66.7%) of obese and 14 (33.3%) of nonobese showed a nondipping pattern in DBP and was found to be statistically significant (P < 0.001). On comparison between normotensive obese and normotensive nonobese, it was found that SBP non dipping pattern18 (67%) versus 9 (29%) and DBP nondipping pattern 12 (45%) versus 5 (16%) was statistically significant with P = 0.004, 0.016, respectively.
Conclusion: Obese diabetes mellitus subjects had altered ABPM parameters and increased prevalence of nondipping status. In addition, obese diabetic patients who did not give prior history of hypertension were also found to have higher nondipping SBP and DBP patterns.
MeSH term(s) Blood Pressure/physiology ; Blood Pressure Monitoring, Ambulatory ; Cardiovascular Diseases ; Circadian Rhythm/physiology ; Cross-Sectional Studies ; Diabetes Mellitus/epidemiology ; Humans ; Hypertension/complications ; Hypertension/epidemiology ; Obesity/complications ; Obesity/epidemiology ; Risk Factors
Language English
Publishing date 2022-10-06
Publishing country India
Document type Journal Article
ZDB-ID 2165792-0
ISSN 0975-5764 ; 0975-5764
ISSN (online) 0975-5764
ISSN 0975-5764
DOI 10.4103/aam.aam_65_21
Database MEDical Literature Analysis and Retrieval System OnLINE

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