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  1. AU="Matija, Lidija"
  2. AU=Glasgow Stacey M
  3. AU="Vlasov, E A"
  4. AU="Paresi, Chelsea" AU="Paresi, Chelsea"
  5. AU="Kalionis, Bill"
  6. AU="Braicu, Elena Ioana"
  7. AU=Vanholder R
  8. AU="Spriano, G (Humanitas Clinical And Research Center Irccs"
  9. AU="Bukowski, Leigh A"
  10. AU="Sestayo, Y"
  11. AU="Billes, Viktor"
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  14. AU="Fayolle, Adeline"
  15. AU="Jang Hoon Kim"
  16. AU="Person, Maria D"
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  18. AU="Mallo, Federico"
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  31. AU="G.Kang, "
  32. AU="Djimdé, Abdoulaye"
  33. AU="Bone, Nathaniel"
  34. AU="Zhou, Yuewen"
  35. AU="Lynch, Stephen M"
  36. AU=Collins Jannette
  37. AU=Kim Soo-Kyoung
  38. AU=Atkinson Sarah H.
  39. AU=Ma Chunlong
  40. AU="Park, Youngjin"
  41. AU="Lakbita, Omar"
  42. AU=ElGokhy Sherin M
  43. AU="Stegmaier, Sabine"
  44. AU="Simons, Gemma N"
  45. AU="Domínguez-Zorita, Sonia"
  46. AU="Nakashima, Ayaka"
  47. AU="Skorecki, Karl"
  48. AU=Ibrahim Salwa
  49. AU=Geocadin Romergryko G
  50. AU="Leroy, J"
  51. AU="Wilson, Peter H"
  52. AU="Cunha, Carla Baroni"

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  1. Artikel ; Online: Opto-magnetic imaging spectroscopy in analyzing rotary NiTi endodontic instruments.

    Jovanović-Medojević, Milica / Dragičević, Aleksandra / Milanović, Ivana / Matija, Lidija / Živković, Slavoljub

    Journal of the mechanical behavior of biomedical materials

    2023  Band 141, Seite(n) 105789

    Abstract: Intra-canal fracture of rotary NiTi instruments occurs due to torsional stress, cyclic fatigue, or a combination of these two factors. Broken instruments are a serious obstacle to shaping, cleaning, and filling of the root canal and can adversely affect ... ...

    Abstract Intra-canal fracture of rotary NiTi instruments occurs due to torsional stress, cyclic fatigue, or a combination of these two factors. Broken instruments are a serious obstacle to shaping, cleaning, and filling of the root canal and can adversely affect the outcome of endodontic therapy. The aim of this study was to examine the magnetic properties and ultrastructural changes of new, used, and fractured NiTi instruments using opto-magnetic imaging spectroscopy (OMIS). The study included three sets of different types of rotary instruments: MTwo (VDW, Munich, Germany), Pro Taper Universal (Dentsply Maillefer, Ballaigues, Switzerland), and BioRace (FKG DENTAIRE Swiss Dental Products, Le Crêt-du-Locle Switzerland). Root canal shaping was performed on root canals with different curvatures, and after intra-canal fracture, instruments of the same type (new, used, and fractured) were analyzed using OMIS at the Faculty of Mechanical Engineering, University of Belgrade. The obtained results showed a coincidence of peak localization for the used instruments that did not suffer a fracture, as well as for new, unused instruments of all examined groups. Additionally, there was a coincidence of peak intensities for new and fractured instruments in all groups. The specific treatment of electropolishing of the active surface of BioRace instruments caused a completely different electromagnetic response compared to conventional NiTi sets of tested instruments. New, unused BioRace instruments had the most pronounced positive (5.6078 n.a.u. x1000) and negative (-8.5218 n.a.u. x1000) intensity values. The analysis of NiTi instruments using opto-magnetic imaging spectroscopy indicated changes in the magnetic properties after their instrumentation.
    Mesh-Begriff(e) Root Canal Preparation ; Equipment Failure ; Rotation ; Spectrum Analysis ; Titanium/chemistry ; Magnetic Phenomena ; Equipment Design ; Dental Alloys ; Materials Testing
    Chemische Substanzen titanium nickelide (12035-60-8) ; Titanium (D1JT611TNE) ; Dental Alloys
    Sprache Englisch
    Erscheinungsdatum 2023-03-23
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2378381-3
    ISSN 1878-0180 ; 1751-6161
    ISSN (online) 1878-0180
    ISSN 1751-6161
    DOI 10.1016/j.jmbbm.2023.105789
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  2. Artikel ; Online: Glucose concentration monitoring using near-infrared spectrum of spent dialysis fluid in hemodialysis patients

    Matović Valentina / Trbojević-Stanković Jasna / Jeftić Branislava / Matija Lidija

    Srpski Arhiv za Celokupno Lekarstvo, Vol 148, Iss 11-12, Pp 706-

    2020  Band 710

    Abstract: Introduction/Objective. Diabetic nephropathy leading to end-stage renal disease is a major health problem worldwide. Hemodialysis (HD) treatment is associated with glycemia variations. Diabetic patients on HD might benefit from a non-invasive online ... ...

    Abstract Introduction/Objective. Diabetic nephropathy leading to end-stage renal disease is a major health problem worldwide. Hemodialysis (HD) treatment is associated with glycemia variations. Diabetic patients on HD might benefit from a non-invasive online glycemia monitoring system. The aim of this study was to assess the glucose concentration from the matrix of the spent dialysate fluid using near-infrared (NIR) spectroscopy. Methods. Blood samples and spent dialysate were collected in the 15th minute of the HD treatment from 15 patients. The spent dialysis fluid was characterized by a NIR spectrometer in the range of 900–1300 nm. In order to apply the artificial neural network (ANN) and train it, the MATLAB NFTOOL program was used. The testing and training of the ANN were executed using the NIR spectrum of the spent dialysis fluid as input, and the glucose concentration as output. Results. A significant correlation in excess of 93% between the NIR spectrum of the spent dialysate and the blood glucose concentration (3–9 mmol/l) was found. Conclusions. NIR spectroscopy is a non-invasive and reliable method of glycemia monitoring which can be used in maintaining HD patients.
    Schlagwörter hemodialysis ; machine learning ; spent dialysate ; vis-nir ; patient-specific ; Medicine ; R
    Thema/Rubrik (Code) 670
    Sprache Englisch
    Erscheinungsdatum 2020-01-01T00:00:00Z
    Verlag Serbian Medical Society
    Dokumenttyp Artikel ; Online
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  3. Artikel ; Online: Predicting anemia using NIR spectrum of spent dialysis fluid in hemodialysis patients.

    Matović, Valentina / Jeftić, Branislava / Trbojević-Stanković, Jasna / Matija, Lidija

    Scientific reports

    2021  Band 11, Heft 1, Seite(n) 10549

    Abstract: Anemia is commonly present in hemodialysis (HD) patients and significantly affects their survival and quality of life. NIR spectroscopy and machine learning were used as a method to detect anemia in hemodialysis patients. The aim of this investigation ... ...

    Abstract Anemia is commonly present in hemodialysis (HD) patients and significantly affects their survival and quality of life. NIR spectroscopy and machine learning were used as a method to detect anemia in hemodialysis patients. The aim of this investigation has been to evaluate the near-infrared spectroscopy (NIRS) as a method for non-invasive on-line detection of anemia parameters from HD effluent by assessing the correlation between the spectrum of spent dialysate in the wavelength range of 700-1700 nm and the levels of hemoglobin (Hb), red blood cells (RBC), hematocrit (Hct), iron (Fe), total iron binding capacity (TIBC), ferritin (FER), mean corpuscular volume (MCV) and mean corpuscular hemoglobin concentration (MCHC) in patient blood. The obtained correlation coefficient (R) for RBC was 0.93, for Hb 0.92, for Fe 0.94, for TIBC 0.96, for FER 0.91, for Hct 0.94, for MCV 0.92, for MCHC 0.92 and for MCH 0.93. The observed high correlations between the NIR spectrum of the dialysate fluid and the levels of the studied variables support the use of NIRS as a promising method for on-line monitoring of anemia and iron saturation parameters in HD patients.
    Mesh-Begriff(e) Anemia, Iron-Deficiency/blood ; Anemia, Iron-Deficiency/therapy ; Erythrocyte Indices ; Hemoglobins/analysis ; Humans ; Monitoring, Physiologic/methods ; Quality of Life ; Renal Dialysis ; Spectroscopy, Near-Infrared/methods
    Chemische Substanzen Hemoglobins
    Sprache Englisch
    Erscheinungsdatum 2021-05-18
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-021-88821-4
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  4. Artikel: Comparative Studies of the Structural and Physicochemical Properties of the First Fullerene Derivative FD-C

    Koruga, Djuro / Stanković, Ivana / Matija, Lidija / Kuhn, Dietmar / Christ, Bastian / Dembski, Sofia / Jevtić, Nenad / Janać, Jelena / Pavlović, Vladimir / De Wever, Bart

    Nanomaterials (Basel, Switzerland)

    2024  Band 14, Heft 5

    Abstract: In order to maximally reduce the toxicity of fullerenol (the first derivative of ... ...

    Abstract In order to maximally reduce the toxicity of fullerenol (the first derivative of C
    Sprache Englisch
    Erscheinungsdatum 2024-03-06
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano14050480
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  5. Artikel ; Online: Employing machine learning to assess the accuracy of near-infrared spectroscopy of spent dialysate fluid in monitoring the blood concentrations of uremic toxins

    Trbojević-Stanković Jasna B. / Matović Valentina D. / Jeftić Branislava D. / Nešić Dejan / Odović Jadranka V. / Perović-Blagojević Iva / Topalović Nikola / Matija Lidija R.

    Archives of Biological Sciences, Vol 75, Iss 3, Pp 309-

    2023  Band 317

    Abstract: Hemodialysis (HD) removes nitrogenous waste products from patients’ blood through a semipermeable membrane along a concentration gradient. Near-infrared spectroscopy (NIRS) is an underexplored method of monitoring the concentrations of several molecules ... ...

    Abstract Hemodialysis (HD) removes nitrogenous waste products from patients’ blood through a semipermeable membrane along a concentration gradient. Near-infrared spectroscopy (NIRS) is an underexplored method of monitoring the concentrations of several molecules that reflect the efficacy of the HD process in dialysate samples. In this study, we aimed to evaluate NIRS as a technique for the non-invasive detection of uremic solutes by assessing the correlations between the spectrum of the spent dialysate and the serum levels of urea, creatinine, and uric acid. Blood and dialysate samples were taken from 35 patients on maintenance HD. The absorption spectrum of each dialysate sample was measured three times in the wavelength range of 700-1700 nm, resulting in a dataset with 315 spectra. The artificial neural network (ANN) learning technique was used to assess the correlations between the recorded NIR-absorbance spectra of the spent dialysate and serum levels of selected uremic toxins. Very good correlations between the NIR-absorbance spectra of the spent dialysate fluid with serum urea (R=0.91) and uric acid (R=0.91) and an excellent correlation with serum creatinine (R=0.97) were obtained. These results support the application of NIRS as a non-invasive, safe, accurate, and repetitive technique for online monitoring of uremic toxins to assist clinicians in assessing HD efficiency and individualization of HD treatments.
    Schlagwörter hemodialysis ; machine learning ; near-infrared spectroscopy ; urea ; creatinine ; Biology (General) ; QH301-705.5
    Thema/Rubrik (Code) 630
    Sprache Englisch
    Erscheinungsdatum 2023-01-01T00:00:00Z
    Verlag University of Belgrade, University of Novi Sad
    Dokumenttyp Artikel ; Online
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  6. Artikel: The Second Derivative of Fullerene C

    Matija, Lidija R / Stankovic, Ivana Mladen / Puric, Milica / Miličić, Milica / Maksimović-Ivanić, Danijela / Mijatovic, Sanja / Krajnović, Tamara / Gordic, Vuk / Koruga, Djuro Lj

    Micromachines

    2023  Band 14, Heft 12

    Abstract: The human body contains 60-70% water, depending on age. As a body fluid, it is not only a medium in which physical and chemical processes take place, but it is also one of the active mediators. Water is the richest substance with non-covalent hydrogen ... ...

    Abstract The human body contains 60-70% water, depending on age. As a body fluid, it is not only a medium in which physical and chemical processes take place, but it is also one of the active mediators. Water is the richest substance with non-covalent hydrogen bonds. Water molecules, by themselves (in vacuum), are diamagnetic but when organized into clusters, they become diamagnetic or paramagnetic. Also, biomolecules (DNA, collagen, clathrin, and other proteins) have non-covalent hydrogen bonds in their structure. The interaction, as well as signal transmission, between water and biomolecules is achieved through the vibrations of covalent and non-covalent hydrogen bonds, which determine the state and dynamics of conformational changes in biomolecules. Disruptive conformational changes in biomolecules, cells, and tissues lead to their dysfunctionality, so they are a frequent cause of many disorders and diseases. For example, the rearrangement of hydrogen bonding due to mitochondrial disease mutation in cytochrome bc1 disturbs heme bH redox potential and spin state. In order to prevent and repair the dysfunctional conformational changes, a liquid substance was developed based on the second derivative of the C
    Sprache Englisch
    Erscheinungsdatum 2023-11-25
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2620864-7
    ISSN 2072-666X
    ISSN 2072-666X
    DOI 10.3390/mi14122152
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  7. Artikel ; Online: Comparative Studies of the Structural and Physicochemical Properties of the First Fullerene Derivative FD-C60 (Fullerenol) and Second Fullerene Derivate SD-C60 (3HFWC)

    Koruga, Djuro / Stanković, Ivana / Matija, Lidija / Kuhn, Dietmar / Christ, Bastian / Dembski, Sofia / Jevtić, Nenad / Janać, Jelena / Pavlović, Vladimir / Wever, Bart de

    2024  

    Abstract: In order to maximally reduce the toxicity of fullerenol (the first derivative of C60, FD-C60), and increase its biomedical efficiency, the second derivative SD-C60 (3HFWC, Hyper-Harmonized Hydroxylated Fullerene Water Complex) was created. Several ... ...

    Abstract In order to maximally reduce the toxicity of fullerenol (the first derivative of C60, FD-C60), and increase its biomedical efficiency, the second derivative SD-C60 (3HFWC, Hyper-Harmonized Hydroxylated Fullerene Water Complex) was created. Several different methods were applied in the comparative characterization of FD-C60 and SD-C60 with the same OH groups in their core. FD-C60 as an individual structure was about 1.3 nm in size, while SD-C60 as an individual structure was 10-30 nm in size. Based on ten physicochemical methods and techniques, FD-C60 and SD-C60 were found to be two different substances in terms of size, structure, and physicochemical properties; FD-C60, at 100 °C, had endothermic characteristics, while SD-C60, at 133 °C, had exothermic characteristics; FD-C60 did not have water layers, while SD-C60 had water layers; the zeta potential of FD-C60 was -25.85 mV, while it was -43.29 mV for SD-C60. SD-C60 is a promising substance for use in cosmetics and pharmaceuticals.

    14

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    Schlagwörter AFM/MFM ; endothermic/exothermic properties ; first derivate C60 ; fullerene C60 ; NMR ; second derivate C60 ; TEM ; TGA/DTA-MS-FTIR ; XRD ; zeta potential ; DDC::500 Naturwissenschaften und Mathematik::570 Biowissenschaften ; Biologie
    Thema/Rubrik (Code) 540
    Sprache Englisch
    Erscheinungsland de
    Dokumenttyp Artikel ; Online
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  8. Artikel ; Online: Sensitivity and specificity of ex vivo dermatoscopy: a case series.

    Dobrosavljevic, Danijela / Brasanac, Dimitrije / Glumac, Sofija / Radojevic, Sanja / Matija, Lidija / Stanisavljevic, Dejana

    International journal of dermatology

    2018  Band 57, Heft 8, Seite(n) 915–921

    Abstract: Background: Sensitivity and specificity of ex vivo dermatoscopy (EVD) for malignancy detection of skin tumors is unknown. We sought to assess whether the use of EVD could be a useful adjunct to histopathological diagnosis of pigmented skin tumors, ... ...

    Abstract Background: Sensitivity and specificity of ex vivo dermatoscopy (EVD) for malignancy detection of skin tumors is unknown. We sought to assess whether the use of EVD could be a useful adjunct to histopathological diagnosis of pigmented skin tumors, including cases where complete clinical information is inadequate or missing.
    Materials and methods: EVD was performed on 195 excised, formalin-fixed pigmented skin tumors.
    Results: Of 183 eligible lesions, 104 (56.8%) were melanocytic and 79 (43.2%) nonmelanocytic. Overall, 54 (29.5%) were malignant: 10 melanomas, 39 basal cell carcinomas, and five squamous cell carcinomas. Ex vivo images were devoid of red color. The following colors were seen: light and dark brown, grey, blue, black, and white. All structures typical for pigmented melanocytic and nonmelanocytic lesions were observed. In malignant nonmelanocytic lesions, diagnostic accuracy and sensitivity for malignant/benign decision was not better when combining visual assessment and EVD but diagnostic specificity improved by 3.0%. For melanoma, combined diagnostics improved diagnostic accuracy, sensitivity, and specificity for 9.6, 30.0, and 7.5%, respectively.
    Conclusion: For dermatopathologists, EVD offers increased specificity for all categories of tumors and increased diagnostic accuracy, sensitivity, and specificity for melanoma. With EVD view, the dermatopathologist can instantly find areas of interest, thus minimizing the possibility for missing a malignant lesion.
    Mesh-Begriff(e) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Carcinoma, Basal Cell/diagnostic imaging ; Carcinoma, Basal Cell/pathology ; Carcinoma, Basal Cell/surgery ; Carcinoma, Squamous Cell/diagnostic imaging ; Carcinoma, Squamous Cell/pathology ; Carcinoma, Squamous Cell/surgery ; Child ; Child, Preschool ; Color ; Dermoscopy ; Humans ; Melanoma/diagnostic imaging ; Melanoma/pathology ; Melanoma/surgery ; Middle Aged ; Sensitivity and Specificity ; Skin Neoplasms/diagnostic imaging ; Skin Neoplasms/pathology ; Skin Neoplasms/surgery ; Young Adult
    Sprache Englisch
    Erscheinungsdatum 2018-05-23
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 412254-9
    ISSN 1365-4632 ; 0011-9059 ; 1461-1244
    ISSN (online) 1365-4632
    ISSN 0011-9059 ; 1461-1244
    DOI 10.1111/ijd.14042
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  9. Artikel ; Online: Characterization of nanophotonic soft contact lenses based on poly (2-hydroxyethyl methacrylate) and fullerene

    Debeljković Aleksandra D. / Matija Lidija R. / Koruga Đuro Lj.

    Hemijska Industrija, Vol 67, Iss 6, Pp 861-

    2013  Band 870

    Abstract: This work presents comparative research of characteristics of a basic and new nanophotonic material, the latter of which was obtained by incorporation fullerene, C60, in the base material for soft contact lenses. The basic (SL38) and nanophotonic ... ...

    Abstract This work presents comparative research of characteristics of a basic and new nanophotonic material, the latter of which was obtained by incorporation fullerene, C60, in the base material for soft contact lenses. The basic (SL38) and nanophotonic materials (SL38-A) for soft contact lenses were obtained by radical polymerization of 2-hydroxyethyl methacrylate and 2-hydroxyethyl methacrylate and fullerene, which were derived by the technology in the production lab of the company Soleko (Milan, Italy). The materials were used for production of soft contact lenses in the company Optix (Belgrade, Serbia) for the purposes of this research. Fullerene was used due to its apsorption transmission characteristics in ultraviolet, visible and near infrared spectrum. For the purposes of material characterization for potential application as soft contact lenses, network parameters were calculated and SEM analysis of the materials was performed while the optical properties of the soft contact lenses were measured by a Rotlex device. The values of the diffusion exponent, n, close to 0.5 indicated Fick's kinetics corresponding to diffusion. The investigated hydrogels could be classified as nonporous hydrogels. With Rotlex device, values of optical power and map of defects were showed. The obtained values of optical power and map of defects showed that the optical power of synthesized nanophotonic soft contact lens is identical to the nominal value while this was not the case for the basic lens. Also, the quality of the nanophotonic soft contact lens is better than the basic soft contact lens. Hence, it is possible to synthesize new nanophotonic soft contact lenses of desired optical characteristics, implying possibilities for their application in this field.
    Schlagwörter nanophotonic soft contact lenses ; PHEMA ; fullerenes ; optical power ; Chemistry ; QD1-999 ; Science ; Q
    Thema/Rubrik (Code) 670
    Sprache Englisch
    Erscheinungsdatum 2013-01-01T00:00:00Z
    Verlag Association of Chemical Engineers, Belgrade
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  10. Artikel ; Online: Electrical properties of human skin as aging biomarkers.

    Simić-Krstić, Jovana B / Kalauzi, Aleksandar J / Ribar, Srdjan N / Matija, Lidija R / Misevic, Gradimir N

    Experimental gerontology

    2014  Band 57, Seite(n) 163–167

    Abstract: A non-invasive bioimpedance spectroscopy (BIS) and Cole-Cole impedance model parameters (R0, R∞, τ and α) were used to analyze electrical properties of intact and stripped human skin for both gender subjects divided into younger and older age groups. R0, ...

    Abstract A non-invasive bioimpedance spectroscopy (BIS) and Cole-Cole impedance model parameters (R0, R∞, τ and α) were used to analyze electrical properties of intact and stripped human skin for both gender subjects divided into younger and older age groups. R0, R∞ and τ significantly increased while α significantly decreased with age in stripped skin for both genders (p<0.031). Using pooled data with respect to age, gender and skin stripping, R0, R∞ and τ values were shown to increase with age (p<0.0034), R0, τ and α were different between genders (p<0.024) and R0, R∞ and τ decreased with skin stripping (p<0.000008). All of four Cole-Cole parameters were age dependent with specific differences observed for genders and intact and stripped skin layers. Therefore, Cole-Cole parameters, obtained by non-invasive BIS measurements, are a new type of age dependent biomarkers.
    Mesh-Begriff(e) Adult ; Aged ; Aged, 80 and over ; Aging/physiology ; Biomarkers ; Electric Impedance ; Electrophysiological Phenomena ; Female ; Humans ; Male ; Middle Aged ; Skin Physiological Phenomena ; Young Adult
    Chemische Substanzen Biomarkers
    Sprache Englisch
    Erscheinungsdatum 2014-09
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 390992-x
    ISSN 1873-6815 ; 0531-5565
    ISSN (online) 1873-6815
    ISSN 0531-5565
    DOI 10.1016/j.exger.2014.06.001
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