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  1. Article ; Online: A Case of S1Q3T3-A Classic Nonspecific Electrocardiogram Finding.

    Pillai, Rohit / Matos, Jason D

    JAMA internal medicine

    2023  Volume 183, Issue 12, Page(s) 1393–1394

    MeSH term(s) Humans ; Electrocardiography ; Dyspnea
    Language English
    Publishing date 2023-10-30
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2699338-7
    ISSN 2168-6114 ; 2168-6106
    ISSN (online) 2168-6114
    ISSN 2168-6106
    DOI 10.1001/jamainternmed.2023.3623
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Kounis Syndrome After Administration of Ultrasound Enhancing Agent.

    Yopes, Margot C / Larnard, Emily A / Liu, Spencer D / Stout, Jessica L / Matos, Jason D / Osborn, Eric A / Strom, Jordan B

    Circulation. Cardiovascular imaging

    2024  Volume 17, Issue 3, Page(s) e016362

    MeSH term(s) Humans ; Kounis Syndrome ; Myocardial Infarction ; Ultrasonography
    Language English
    Publishing date 2024-02-28
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2435045-X
    ISSN 1942-0080 ; 1941-9651
    ISSN (online) 1942-0080
    ISSN 1941-9651
    DOI 10.1161/CIRCIMAGING.123.016362
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Post-Cardiac Surgery Atrial Fibrillation: Risks, Mechanisms, Prevention, and Management.

    Matos, Jason D / Sellke, Frank W / Zimetbaum, Peter

    Cardiac electrophysiology clinics

    2021  Volume 13, Issue 1, Page(s) 133–140

    Abstract: Atrial fibrillation (AF) is the most common complication of cardiac surgery (CS). There are numerous risk factors, proposed mechanisms, and financial/clinical implications of post-CS AF (PCSAF). Management involves 2 arms: prevention and treatment. This ... ...

    Abstract Atrial fibrillation (AF) is the most common complication of cardiac surgery (CS). There are numerous risk factors, proposed mechanisms, and financial/clinical implications of post-CS AF (PCSAF). Management involves 2 arms: prevention and treatment. This review highlights and summarizes previous literature on PCSAF and challenges the standard dogma regarding anticoagulation, particularly in the short term.
    MeSH term(s) Anticoagulants ; Atrial Fibrillation ; Cardiac Surgical Procedures/adverse effects ; Humans ; Postoperative Complications ; Risk Factors
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2021-01-08
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 1877-9190
    ISSN (online) 1877-9190
    DOI 10.1016/j.ccep.2020.11.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Wide Complex Tachycardia in a Young Woman.

    Raber, Inbar / Matos, Jason D / Buxton, Alfred E

    JACC. Case reports

    2021  Volume 3, Issue 11, Page(s) 1357–1359

    Abstract: A 27-year-old woman presented with palpitations and was found to have episodes of a non-sustained wide complex tachycardia. In this report, we discuss a differential diagnosis for the patient's wide complex tachycardia and the important ECG findings ... ...

    Abstract A 27-year-old woman presented with palpitations and was found to have episodes of a non-sustained wide complex tachycardia. In this report, we discuss a differential diagnosis for the patient's wide complex tachycardia and the important ECG findings which lead to her diagnosis. (
    Language English
    Publishing date 2021-09-01
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2666-0849
    ISSN (online) 2666-0849
    DOI 10.1016/j.jaccas.2021.04.045
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  5. Article ; Online: Atrial Fibrillation.

    Matos, Jason D / Gavin, Michael C / Gelfand, Eli V

    The New England journal of medicine

    2021  Volume 385, Issue 4, Page(s) 383

    MeSH term(s) Atrial Fibrillation ; Humans
    Language English
    Publishing date 2021-07-21
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2103291
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  6. Article ; Online: The spatial ventricular gradient is associated with adverse outcomes in acute pulmonary embolism.

    Stabenau, Hans Friedrich / Marcus, Mason / Matos, Jason D / McCormick, Ian / Litmanovich, Diana / Manning, Warren J / Carroll, Brett J / Waks, Jonathan W

    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc

    2023  Volume 28, Issue 3, Page(s) e13041

    Abstract: Background: The spatial ventricular gradient (SVG) is a vectorcardiographic measurement that reflects cardiac loading conditions via electromechanical coupling.: Objectives: We hypothesized that the SVG is correlated with right ventricular (RV) ... ...

    Abstract Background: The spatial ventricular gradient (SVG) is a vectorcardiographic measurement that reflects cardiac loading conditions via electromechanical coupling.
    Objectives: We hypothesized that the SVG is correlated with right ventricular (RV) strain and is prognostic of adverse events in patients with acute pulmonary embolism (PE).
    Methods: Retrospective, single-center study of patients with acute PE. Electrocardiogram (ECG), imaging, and outcome data were obtained. SVG components were regressed on tricuspid annular plane systolic excursion (TAPSE), qualitative RV dysfunction, and RV/left ventricular (LV) ratio. Odds of adverse outcomes (30-day mortality, vasopressor requirement, or advanced therapy) after PE were regressed on demographics, RV/LV ratios, traditional ECG signs of RV dysfunction, and SVG components using a logit model.
    Results: ECGs from 317 patients (48% male, age 63.1 ± 16.6 years) with acute PE were analyzed; 36 patients (11.4%) experienced an adverse event. Worse RV hypokinesis, larger RV/LV ratio, and smaller TAPSE were associated with smaller SVG X and Y components, larger SVG Z components, and smaller SVG vector magnitude (p < .001 for all). In multivariable logistic regression, odds of adverse events after PE decreased with increasing SVG magnitude and TAPSE (OR 0.32 and 0.54 per standard deviation increase; p = .03 and p = .004, respectively). Receiver operating characteristic (ROC) analysis showed that, when combined with imaging, replacing traditional ECG criteria with the SVG significantly improved the area under the ROC from 0.70 to 0.77 (p = .01).
    Conclusion: The SVG is correlated with RV dysfunction and adverse outcomes in acute PE and has a better prognostic value than traditional ECG markers.
    MeSH term(s) Humans ; Male ; Middle Aged ; Aged ; Female ; Retrospective Studies ; Electrocardiography ; Pulmonary Embolism/diagnostic imaging ; Acute Disease ; Prognosis
    Language English
    Publishing date 2023-01-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1325530-7
    ISSN 1542-474X ; 1082-720X
    ISSN (online) 1542-474X
    ISSN 1082-720X
    DOI 10.1111/anec.13041
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  7. Article: Controversy Surrounding ROCKET-AF: A Call for Transparency, But Should We Be Changing Practice?

    Matos, Jason D / Zimetbaum, Peter J

    Arrhythmia & electrophysiology review

    2016  Volume 5, Issue 1, Page(s) 12–13

    Language English
    Publishing date 2016-07-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2813970-7
    ISSN 2050-3377 ; 2050-3369
    ISSN (online) 2050-3377
    ISSN 2050-3369
    DOI 10.15420/aer.2016.24.2
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  8. Article: Tailored Anticoagulation for Thromboembolic Risk Reduction in Paroxysmal Atrial Fibrillation.

    Matos, Jason D / Waks, Jonathan W / Zimetbaum, Peter J

    The Journal of innovations in cardiac rhythm management

    2018  Volume 9, Issue 4, Page(s) 3116–3125

    Abstract: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, affecting up to six million people in the United States and more than 35 million individuals worldwide. Thromboembolism, including stroke, represents the most common AF-related ... ...

    Abstract Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, affecting up to six million people in the United States and more than 35 million individuals worldwide. Thromboembolism, including stroke, represents the most common AF-related morbidity and mortality and data indicate that anticoagulation can mitigate this risk by 65%. Our understanding of thromboembolism in AF, however, remains incomplete, and the mechanisms by which AF increases thromboembolic risk are areas of ongoing investigation and debate. Current guidelines do not differentiate between the frequency and duration of AF episodes (AF burden) when selecting which patients with AF should be treated with anticoagulation for thromboembolic risk reduction. Recent data, primarily using cardiac implantable electronic devices (CIEDs) such as pacemakers, implantable cardioverter-defibrillators, and implantable loop recorders, however, have challenged this longstanding notion that AF burden does not influence thromboembolic risk. Continuous and automated cardiac rhythm monitoring via CIEDs with accurate and rapid acquisition and transmission of rhythm data also affords the opportunity to study the relationship between AF burden and thromboembolism and novel ways to reduce thromboembolic risk while minimizing the risk associated with chronic anticoagulation use. This manuscript will review the associations between subclinical, CIED-detected atrial arrhythmias and thromboembolic events. It will also discuss the emergence of "tailored anticoagulation," an anticoagulation strategy wherein CIEDs and remote AF monitoring are employed to allow dynamic administration of oral anticoagulation only around episodes of AF, and the holding of anticoagulation during prolonged periods of sinus rhythm when the thromboembolic risk associated with AF is presumably very low.
    Language English
    Publishing date 2018-04-15
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2156-3977
    ISSN 2156-3977
    DOI 10.19102/icrm.2018.090404
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  9. Article ; Online: Adjusting Atrial Size Parameters for Body Surface Area: Does it Affect the Association with Pulmonary Embolism-related Adverse Events?

    Kirkbride, Rachael R / Aviram, Galit / Heidinger, Benedikt H / Liberman, Yuval / Libauske, Aurelija / Liubauskas, Rokas / Tridente, Daniela M / Brook, Alexander / DaBreo, Dominique C / Monteiro Filho, Antonio C / Carroll, Brett J / Matos, Jason D / McCormick, Ian C / Manning, Warren J / Litmanovich, Diana E

    Journal of thoracic imaging

    2024  

    Abstract: Purpose: Small left atrial (LA) volume was recently reported to be one of the best predictors of acute pulmonary embolism (PE)-related adverse events (AE). There is currently no data available regarding the impact that body surface area (BSA)-indexing ... ...

    Abstract Purpose: Small left atrial (LA) volume was recently reported to be one of the best predictors of acute pulmonary embolism (PE)-related adverse events (AE). There is currently no data available regarding the impact that body surface area (BSA)-indexing of atrial measurements has on the association with PE-related adverse events. Our aim is to assess the impact of indexing atrial measurements to BSA on the association between computed tomography (CT) atrial measurements and AE.
    Materials and methods: Retrospective study (IRB: 2015P000425). A database of hospitalized patients with acute PE diagnosed on CT pulmonary angiography (CTPA) between May 2007 and December 2014 was reviewed. Right and left atrial volume, largest axial area, and axial diameters were measured. Patients undergo both echocardiographies (from which the BSA was extracted) and CTPAs within 48 hours of the procedure. The patient's body weight was measured during each admission. LA measurements were correlated to AE (defined as the need for advanced therapy or PE-related mortality at 30 days) before and after indexing for BSA. The area under the ROC curve was calculated to determine the predictive value of the atrial measurements in predicting AE.
    Results: The study included 490 acute PE patients; 62 (12.7%) had AE. There was a significant association of reduced BSA-indexed and non-indexed LA volume (both <0.001), area (<0.001 and 0.001, respectively), and short-axis diameters (both <0.001), and their respective RA/LA ratios (all <0.001) with AE. The AUC values were similar for BSA-indexed and non-indexed LA volume, diameters, and area with LA volume measurements being the best predictor of adverse outcomes (BSA-indexed AUC=0.68 and non-indexed AUC=0.66), followed by non-indexed LA short-axis diameter (indexed AUC=0.65, non-indexed AUC=0.64), and LA area (indexed AUC=0.64, non-indexed AUC=0.63).
    Conclusion: Adjusting for BSA does not substantially affect the predictive ability of atrial measurements on 30-day PE-related adverse events, and therefore, this adjustment is not necessary in clinical practice. While LA volume is the better predictor of AE, LA short-axis diameter has a similar predictive value and is more practical to perform clinically.
    Language English
    Publishing date 2024-04-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632900-7
    ISSN 1536-0237 ; 0883-5993
    ISSN (online) 1536-0237
    ISSN 0883-5993
    DOI 10.1097/RTI.0000000000000781
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  10. Article ; Online: Quality and diagnostic performance of coronary computed tomography angiogram (CCTA): A comparison between pre-liver and pre-kidney transplant patients.

    Kirkbride, Rachael R / Larkin, Emily / Tuttle, Mark K / Nicholson, Michael D / Jiang, Brian G / Liubauskas, Rokas / Matos, Jason D / Gavin, Michael / Litmanovich, Diana E

    European journal of radiology

    2021  Volume 143, Page(s) 109886

    Abstract: Purpose: Assess and compare the quality and diagnostic performance of CCTA between pre-liver and pre-kidney transplant patients, and gauge impact of CCTA on ICA requirements.: Methods: Patients without known coronary artery disease (CAD) were ... ...

    Abstract Purpose: Assess and compare the quality and diagnostic performance of CCTA between pre-liver and pre-kidney transplant patients, and gauge impact of CCTA on ICA requirements.
    Methods: Patients without known coronary artery disease (CAD) were selected for CCTA if considered high-risk or after abnormal stress testing. All pre-liver and pre-kidney CCTAs between March 2018 and August 2020 were retrospectively included. CCTA quality was qualitatively graded as excellent/good/fair/poor, and CAD graded as < or ≥50% stenosis. Heart rate, coronary artery calcium (CAC) scores, and fractional flow reserve CT (FFR
    Results: 162 pre-transplant patients (91 pre-liver, 71 pre-kidney). Pre-kidney patients had poorer CCTA quality (p = 0.04) and higher heart rate (median: 65 bpm vs 60 bpm, p < 0.001). Out of 147 diagnostic CCTAs (pre-liver: 84, pre-kidney: 63), 73 (49.7%) had a ≥50% stenosis (pre-liver: 38 (45.2%), pre-kidney:35 (55.6%)). 12/38 (31.6%) had a significantly reduced FFR
    Conclusion: Diagnostic-quality CCTAs in high-risk pre-transplant patients are achievable and can greatly reduce ICA requirements by excluding significant CAD. CCTA quality is poorer in pre-kidney transplant patients compared to pre-liver, possibly due to higher heart rate.
    MeSH term(s) Computed Tomography Angiography ; Coronary Angiography ; Coronary Artery Disease/diagnostic imaging ; Coronary Stenosis ; Fractional Flow Reserve, Myocardial ; Humans ; Kidney Transplantation ; Liver ; Predictive Value of Tests ; Retrospective Studies ; Tomography, X-Ray Computed
    Language English
    Publishing date 2021-07-31
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 138815-0
    ISSN 1872-7727 ; 0720-048X
    ISSN (online) 1872-7727
    ISSN 0720-048X
    DOI 10.1016/j.ejrad.2021.109886
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