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  1. AU="Matos, Stênio Gonçalves da Silva"
  2. AU="Robinson, James B"
  3. AU="An, Dowon"
  4. AU="Mohammad Shahrooei"
  5. AU="Brandjes, Dees P M"
  6. AU="Zou, J Z"
  7. AU="Kamal Dahan Alsultan"
  8. AU="Ayres-Silva, Jackline P"
  9. AU="Devrim, Fatma"
  10. AU="Michael J Horzewski"
  11. AU="Mumtaz, Nazia"
  12. AU="Elsa R. Treffeisen"
  13. AU="Ram, Natalie"
  14. AU="Azzaoui, Kamal"
  15. AU="Clowney, Billy"
  16. AU="Andrews, Lawrence C."
  17. AU="Arias, Andrés Hugo"
  18. AU="Yeo, B K"
  19. AU="Sultan, Mahmoud H"
  20. AU="Kou, Z Q"
  21. AU="Lamm, L"
  22. AU="Truxius, Lidia"
  23. AU="Xingyi Guo"
  24. AU="Gang Lin"
  25. AU="Oka, T"
  26. AU="Frank-Pearce, Summer G"
  27. AU="Hairi Li"
  28. AU="Park, SungHee"
  29. AU="Pascual-Carreras, Eudald"
  30. AU=Joffe Ari R
  31. AU="Buccafurri, Francesco"
  32. AU="Naomi H. Philip"
  33. AU="P. Naina"
  34. AU="Sigal, Leonard H"
  35. AU="Xu, T" AU="Xu, T"
  36. AU="Mazlout, Adam"
  37. AU="Novak, Cheryl B"
  38. AU="Ren, Zhongmin"
  39. AU="Nadhira Houhou-Fidouh"
  40. AU="Seiffert, Jacqui"
  41. AU=Zhang Zizhen
  42. AU="Bhupender Singh Negi"

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  1. Artikel ; Online: Exposure of adult zebrafish (Danio rerio) to SARS-CoV-2 at predicted environmentally relevant concentrations: Outspreading warns about ecotoxicological risks to freshwater fish.

    Luz, Thiarlen Marinho da / Guimarães, Abraão Tiago Batista / Matos, Stênio Gonçalves da Silva / de Souza, Sindoval Silva / Gomes, Alex Rodrigues / Rodrigues, Aline Sueli de Lima / Durigon, Edison Luiz / Charlie-Silva, Ives / Freitas, Ítalo Nascimento / Islam, Abu Reza Md Towfiqul / Rahman, Md Mostafizur / Silva, Abner Marcelino / Malafaia, Guilherme

    The Science of the total environment

    2023  Band 880, Seite(n) 163269

    Abstract: While the multifaceted social, economic, and public health impacts associated with the COVID-19 pandemic are known, little is known about its effects on non-target aquatic ecosystems and organisms. Thus, we aimed to evaluate the potential ecotoxicity of ... ...

    Abstract While the multifaceted social, economic, and public health impacts associated with the COVID-19 pandemic are known, little is known about its effects on non-target aquatic ecosystems and organisms. Thus, we aimed to evaluate the potential ecotoxicity of SARS-CoV-2 lysate protein (SARS.CoV2/SP02.2020.HIAE.Br) in adult zebrafish (Danio rerio) at predicted environmentally relevant concentrations (0.742 and 2.226 pg/L), by 30 days. Although our data did not show locomotor alterations or anxiety-like or/and anxiolytic-like behavior, we noticed that exposure to SARS-CoV-2 negatively affected habituation memory and social aggregation of animals in response to a potential aquatic predator (Geophagus brasiliensis). An increased frequency of erythrocyte nuclear abnormalities was also observed in animals exposed to SARS-CoV-2. Furthermore, our data suggest that such changes were associated with a redox imbalance [↑ROS (reactive oxygen species), ↑H
    Mesh-Begriff(e) Animals ; Humans ; Zebrafish/physiology ; SARS-CoV-2 ; Oxidative Stress ; Acetylcholinesterase/metabolism ; Ecosystem ; Pandemics ; COVID-19 ; Fresh Water ; Water Pollutants, Chemical/analysis
    Chemische Substanzen Acetylcholinesterase (EC 3.1.1.7) ; Water Pollutants, Chemical
    Sprache Englisch
    Erscheinungsdatum 2023-04-05
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2023.163269
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Exposure to microcrystallized cellulose affects the health of tadpoles and sheds light on the threat these materials pose to amphibians.

    Souza, Sindoval Silva de / Gomes, Alex Rodrigues / Guimarães, Abraão Tiago Batista / Matos, Letícia Paiva de / Mendonça, Juliana Dos Santos / Luz, Thiarlen Marinho da / Matos, Stênio Gonçalves da Silva / Rodrigues, Aline Sueli de Lima / Senthil-Nathan, Sengottayan / Rakib, Md Refat Jahan / Kamaraj, Chinnaperumal / Rocha, Thiago Lopes / Islam, Abu Reza Md Towfiqul / Malafaia, Guilherme

    Environmental pollution (Barking, Essex : 1987)

    2023  Band 343, Seite(n) 123236

    Abstract: The increasing use of cellulose-based materials (CBMs) has provided beneficial applications in different sectors. However, its release into environments may represent an ecological risk, therefore demanding that ecotoxicological studies be conducted to ... ...

    Abstract The increasing use of cellulose-based materials (CBMs) has provided beneficial applications in different sectors. However, its release into environments may represent an ecological risk, therefore demanding that ecotoxicological studies be conducted to understand the risks (current and future) of CBM pollution. Thus, we evaluated the possible effects of microcrystalline cellulose (CMs) in Physalaemus cuvieri tadpoles. After seven days of exposure to CMs (at 58.29 and 100 mg/L), the animals were subjected to behavioral evaluation, and different biomarkers (biometric and biochemical) were evaluated. Although our data do not point to a neurotoxic effect of CMs (inferred by the absence of behavioral changes and changes in AChE and BChE activity), animals exposed to CMs showed differences in body condition. Furthermore, we noticed an increase in the frequency of erythrocyte nuclear abnormalities and DNA damage, which were correlated with the ingestion of CMs. We noticed that the antioxidant activity of tadpoles exposed to CMs (inferred by SOD, CAT, and DPPH radical scavenging activity) was insufficient to control the increase in ROS and MDA production. Furthermore, exposure to CMs induced a predominant Th2-specific immune response, marked by suppressed IFN-γ and increased IL-10 levels, with a consequent reduction in NO levels. Principal component analysis and IBRv-2 indicate, in general, a primarily more toxic response to animals exposed to the highest CM concentration. Therefore, our study evidence that CMs affect the health of P. cuvieri tadpoles and sheds light on the threat these materials pose to amphibians.
    Mesh-Begriff(e) Animals ; Larva ; Anura/physiology ; Antioxidants/pharmacology ; Water Pollutants, Chemical/toxicity
    Chemische Substanzen Antioxidants ; Water Pollutants, Chemical
    Sprache Englisch
    Erscheinungsdatum 2023-12-29
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 280652-6
    ISSN 1873-6424 ; 0013-9327 ; 0269-7491
    ISSN (online) 1873-6424
    ISSN 0013-9327 ; 0269-7491
    DOI 10.1016/j.envpol.2023.123236
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  3. Artikel ; Online: Exposure of adult zebrafish (Danio rerio) to SARS-CoV-2 at predicted environmentally relevant concentrations: Outspreading warns about ecotoxicological risks to freshwater fish

    Luz, Thiarlen Marinho da / Guimarães, Abraão Tiago Batista / Matos, Stênio Gonçalves da Silva / de Souza, Sindoval Silva / Gomes, Alex Rodrigues / Rodrigues, Aline Sueli de Lima / Durigon, Edison Luiz / Charlie-Silva, Ives / Freitas, Ítalo Nascimento / Islam, Abu Reza Md. Towfiqul / Rahman, Md. Mostafizur / Silva, Abner Marcelino / Malafaia, Guilherme

    Science of the Total Environment. 2023 July, v. 880 p.163269-

    2023  

    Abstract: While the multifaceted social, economic, and public health impacts associated with the COVID-19 pandemic are known, little is known about its effects on non-target aquatic ecosystems and organisms. Thus, we aimed to evaluate the potential ecotoxicity of ... ...

    Abstract While the multifaceted social, economic, and public health impacts associated with the COVID-19 pandemic are known, little is known about its effects on non-target aquatic ecosystems and organisms. Thus, we aimed to evaluate the potential ecotoxicity of SARS-CoV-2 lysate protein (SARS.CoV2/SP02.2020.HIAE.Br) in adult zebrafish (Danio rerio) at predicted environmentally relevant concentrations (0.742 and 2.226 pg/L), by 30 days. Although our data did not show locomotor alterations or anxiety-like or/and anxiolytic-like behavior, we noticed that exposure to SARS-CoV-2 negatively affected habituation memory and social aggregation of animals in response to a potential aquatic predator (Geophagus brasiliensis). An increased frequency of erythrocyte nuclear abnormalities was also observed in animals exposed to SARS-CoV-2. Furthermore, our data suggest that such changes were associated with a redox imbalance [↑ROS (reactive oxygen species), ↑H₂O₂ (hydrogen peroxide), ↓SOD (superoxide dismutase), and ↓CAT (catalase)], cholinesterasic effect [↑AChE (acetylcholinesterase) activity], as well as the induction of an inflammatory immune response [↑NO (nitric oxide), ↑IFN-γ (interferon-gamma), and ↓IL-10 (interleukin-10)]. For some biomarkers, we noticed that the response of the animals to the treatments was not concentration-dependent. However, principal component analysis (PCA) and the “Integrated Biomarker Response” index (IBRv2) indicated a more prominent ecotoxicity of SARS-CoV-2 at 2.226 pg/L. Therefore, our study advances knowledge about the ecotoxicological potential of SARS-CoV-2 and reinforces the presumption that the COVID-19 pandemic has negative implications beyond its economic, social, and public health impacts.
    Schlagwörter COVID-19 infection ; Danio rerio ; Geophagus brasiliensis ; Severe acute respiratory syndrome coronavirus 2 ; acetylcholinesterase ; adults ; aggregation behavior ; biomarkers ; catalase ; ecotoxicology ; environment ; erythrocytes ; freshwater fish ; habituation ; hydrogen peroxide ; immune response ; interferon-gamma ; interleukin-10 ; memory ; nitric oxide ; principal component analysis ; public health ; superoxide dismutase ; Ecotoxicity ; New coronavirus ; Environmental toxicology
    Sprache Englisch
    Erscheinungsverlauf 2023-07
    Erscheinungsort Elsevier B.V.
    Dokumenttyp Artikel ; Online
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2023.163269
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  4. Artikel ; Online: Toxicity of carbon nanofibers in earthworms (Lumbricus terrestris) naturally infected with Monocystis sp.

    Montalvão, Mateus Flores / Gomes, Alex Rodrigues / Guimarães, Abraão Tiago Batista / Rodrigues, Aline Sueli de Lima / Matos, Letícia Paiva de / Mendonça, Juliana Dos Santos / da Luz, Thiarlen Marinho / Matos, Stênio Gonçalves da Silva / Rahman, M Safiur / Ragavendran, Chinnasamy / Senthil-Nathan, Sengottayan / Guru, Ajay / Rakib, Md Refat Jahan / Mubarak, Nabisab Mujawar / Rahman, Md Mostafizur / Rocha, Thiago Lopes / Islam, Abu Reza Md Towfiqul / Malafaia, Guilherme

    The Science of the total environment

    2023  Band 906, Seite(n) 167712

    Abstract: Although the ecotoxicity of carbon-based nanomaterials (CBNs) is known, the potential effect of carbon nanofibers (CNFs) on edaphic organisms has been insufficiently explored. Thus, we aimed at the ecotoxicity of CNFs (at 10 and 100 mg/kg) in Lumbricus ... ...

    Abstract Although the ecotoxicity of carbon-based nanomaterials (CBNs) is known, the potential effect of carbon nanofibers (CNFs) on edaphic organisms has been insufficiently explored. Thus, we aimed at the ecotoxicity of CNFs (at 10 and 100 mg/kg) in Lumbricus terrestris earthworms naturally infected with Monocystis sp. After 28 days of exposure, treatments did not affect the survival rate. However, we observed a significant loss of body biomass, and Monocystis sp. infection in seminal vesicles was potentiated by exposure to CNFs. Earthworms exposed to CNFs showed a redox imbalance in the seminal vesicle, muscle, and intestine and an alteration in nitric oxide production in these organs. In muscles, we also noticed a significant reduction in AChE activity in earthworms exposed to CNFs. The histopathological analyses revealed the treatments' significant effect on the structures of the different evaluated tissues. Although we did not notice a concentration-response for several of the biomarkers, when taken together and after the application of Integrated Biomarker Response (IBR) and principal component analysis (PCA), we noticed that the response of earthworms to CNFs at 100 mg/kg showed a more significant deviation from the unexposed group. This was mainly determined by inhibiting antioxidant activity in the seminal vesicle, biochemical biomarkers assessed in muscle and intestine, and histomorphometric muscle biomarkers from earthworms exposed to CNFs at 100 mg/kg. Thus, we demonstrate that CNFs increase the parasite load of Monocystis sp. of adult L. terrestris earthworms and induce biochemical and histopathological changes, especially at 100 mg/kg. Our results point to the additional impact these nanomaterials can have on the health of earthworms, signaling the need for greater attention to their disposal and ecotoxicological effects on soil organisms.
    Mesh-Begriff(e) Animals ; Carbon ; Oligochaeta/physiology ; Nanofibers/toxicity ; Biomarkers ; Soil ; Soil Pollutants/toxicity
    Chemische Substanzen Carbon (7440-44-0) ; Biomarkers ; Soil ; Soil Pollutants
    Sprache Englisch
    Erscheinungsdatum 2023-10-11
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2023.167712
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Verfügbar in ZB MED Köln/Königswinter

    Zs.A 949: Hefte anzeigen Standort:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
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  5. Artikel ; Online: Cellulose microcrystalline: A promising ecofriendly approach to control Culex quinquefasciatus larvae.

    Souza, Sindoval Silva de / Gomes, Alex Rodrigues / Guimarães, Abraão Tiago Batista / Rodrigues, Aline Sueli de Lima / de Matos, Letícia Paiva / Dos Santos Mendonça, Juliana / da Luz, Thiarlen Marinho / Matos, Stênio Gonçalves da Silva / Rahman, M Safiur / Ragavendran, Chinnasamy / Senthil-Nathan, Sengottayan / Guru, Ajay / Rakib, Md Refat Jahan / Mubarak, Nabisab Mujawar / Rahman, Md Mostafizur / Rocha, Thiago Lopes / Islam, Abu Reza Md Towfiqul / Malafaia, Guilherme

    The Science of the total environment

    2023  Band 901, Seite(n) 165952

    Abstract: The growing use of synthetic chemical compounds/substances in vector control of mosquitoes, associated with their adverse effects on the environment and non-target organisms, has demanded the development of eco-friendly alternatives. In this context, ... ...

    Abstract The growing use of synthetic chemical compounds/substances in vector control of mosquitoes, associated with their adverse effects on the environment and non-target organisms, has demanded the development of eco-friendly alternatives. In this context, this study aimed to evaluate the larvicidal action of different cellulose microcrystalline (CMs) concentrations and investigate their toxicity mechanisms in Culex quinquefasciatus fourth instar larvae as a model species. Probit analysis revealed that the median lethal concentrations (LC
    Sprache Englisch
    Erscheinungsdatum 2023-08-01
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2023.165952
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Cellulose microcrystalline: A promising ecofriendly approach to control Culex quinquefasciatus larvae

    Souza, Sindoval Silva de / Gomes, Alex Rodrigues / Guimarães, Abraão Tiago Batista / Rodrigues, Aline Sueli de Lima / de Matos, Letícia Paiva / dos Santos Mendonça, Juliana / da Luz, Thiarlen Marinho / Matos, Stênio Gonçalves da Silva / Rahman, M. Safiur / Ragavendran, Chinnasamy / Senthil-Nathan, Sengottayan / Guru, Ajay / Rakib, Md. Refat Jahan / Mubarak, Nabisab Mujawar / Rahman, Md. Mostafizur / Rocha, Thiago Lopes / Islam, Abu Reza Md. Towfiqul / Malafaia, Guilherme

    Science of the Total Environment. 2023 Nov., v. 901 p.165952-

    2023  

    Abstract: The growing use of synthetic chemical compounds/substances in vector control of mosquitoes, associated with their adverse effects on the environment and non-target organisms, has demanded the development of eco-friendly alternatives. In this context, ... ...

    Abstract The growing use of synthetic chemical compounds/substances in vector control of mosquitoes, associated with their adverse effects on the environment and non-target organisms, has demanded the development of eco-friendly alternatives. In this context, this study aimed to evaluate the larvicidal action of different cellulose microcrystalline (CMs) concentrations and investigate their toxicity mechanisms in Culex quinquefasciatus fourth instar larvae as a model species. Probit analysis revealed that the median lethal concentrations (LC₅₀) for 24 h and 36 h exposure were 100 and 58.29 mg/L, respectively. We also showed that such concentrations induced a redox imbalance in the larvae, marked by an increase in the production of reactive oxygen species (ROS) and thiobarbituric acid reactive substances (TBARS), as well as a reduction in the activity of superoxide dismutase (SOD) and catalase (CAT). Furthermore, different alterations in the external morphology of the larvae were associated with the ingestion of CMs. On the other hand, exposure of adult zebrafish (Danio rerio) to LC₅₀24h and LC₅₀36h for seven days did not induce any behavioral changes or alterations mutagenic, genotoxic, biochemical, or in the production of cytokines IFN-γ and IL-10. Thus, taken together, our study demonstrates for the first time that the use of CMs can constitute a promising strategy in the control of C. quinquefasciatus larvae, combining insecticidal efficiency with an “eco-friendly” approach in the fight against an important mosquito vector of several human diseases.
    Schlagwörter Culex quinquefasciatus ; Danio rerio ; adults ; catalase ; cellulose ; environment ; humans ; ingestion ; instars ; interleukin-10 ; larvicides ; mosquito vectors ; mutagens ; probit analysis ; reactive oxygen species ; superoxide dismutase ; toxicity ; vector control ; Larvicide assay ; Mosquitoes ; Eco-friendly particles ; Zebrafish ; Ecotoxicity
    Sprache Englisch
    Erscheinungsverlauf 2023-11
    Erscheinungsort Elsevier B.V.
    Dokumenttyp Artikel ; Online
    ZDB-ID 121506-1
    ISSN 1879-1026 ; 0048-9697
    ISSN (online) 1879-1026
    ISSN 0048-9697
    DOI 10.1016/j.scitotenv.2023.165952
    Datenquelle NAL Katalog (AGRICOLA)

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