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Article: Utilization of a Silicone Rubber Membrane for Passive Oxygen Supply in a Microbial Fuel Cell Treating Carbon and Nitrogen from Synthetic Coke-Oven Wastewater

Wang, Fengyu / Matsubara, Hirokazu / Nittami, Tadashi / Fujita, Masafumi

Applied biochemistry and biotechnology. 2019 Sept., v. 189, no. 1

2019

Abstract: This study firstly introduced a silicone rubber membrane (SRM) into microbial fuel cell (MFC) for passive oxygen supply to simultaneously remove phenol and nitrogen from synthetic coke-oven wastewater diluted with seawater. Passive oxygen transport with ... ...

Abstract	This study firstly introduced a silicone rubber membrane (SRM) into microbial fuel cell (MFC) for passive oxygen supply to simultaneously remove phenol and nitrogen from synthetic coke-oven wastewater diluted with seawater. Passive oxygen transport with biofilm on the membrane was improved by ~ 18-fold in comparison with the one without a biofilm. In addition, although the oxygen supply was passive, nitrification accounted for 34% of those aeration conditions. It was also found that silicone rubber membrane can control NO2−–N and/or NO3−–N production. A dual-chamber MFC treating the synthetic coke-oven wastewater achieved a maximum power density of 54 mW m−2 with a coulombic efficiency of 2.7%. We conclude that silicone rubber membrane is effective for sustainable coke-oven wastewater treatment in MFCs.
Keywords	aeration ; artificial membranes ; biofilm ; carbon ; microbial fuel cells ; nitrate nitrogen ; nitrification ; nitrite nitrogen ; nitrogen ; oxygen ; phenol ; rubber ; seawater ; silicone ; wastewater ; wastewater treatment
Language	English
Dates of publication	2019-09
Size	p. 217-232.
Publishing place	Springer US
Document type	Article
ZDB-ID	392344-7
ISSN	0273-2289
ISSN	0273-2289
DOI	10.1007/s12010-019-02994-3
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Utilization of a Silicone Rubber Membrane for Passive Oxygen Supply in a Microbial Fuel Cell Treating Carbon and Nitrogen from Synthetic Coke-Oven Wastewater.

Wang, Fengyu / Matsubara, Hirokazu / Nittami, Tadashi / Fujita, Masafumi

Applied biochemistry and biotechnology

2019 Volume 189, Issue 1, Page(s) 217–232

Abstract	This study firstly introduced a silicone rubber membrane (SRM) into microbial fuel cell (MFC) for passive oxygen supply to simultaneously remove phenol and nitrogen from synthetic coke-oven wastewater diluted with seawater. Passive oxygen transport with biofilm on the membrane was improved by ~ 18-fold in comparison with the one without a biofilm. In addition, although the oxygen supply was passive, nitrification accounted for 34% of those aeration conditions. It was also found that silicone rubber membrane can control NO
MeSH term(s)	Bioelectric Energy Sources ; Carbon/administration & dosage ; Membranes, Artificial ; Nitrogen/administration & dosage ; Oxygen/administration & dosage ; Silicone Elastomers/chemistry
Chemical Substances	Membranes, Artificial ; Silicone Elastomers ; Carbon (7440-44-0) ; Nitrogen (N762921K75) ; Oxygen (S88TT14065)
Language	English
Publishing date	2019-04-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	392344-7
ISSN	1559-0291 ; 0273-2289
ISSN (online)	1559-0291
ISSN	0273-2289
DOI	10.1007/s12010-019-02994-3
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Article ; Online: Tuberculosis osteomyelitis in an old fused hip; activated by prednisolone, salazosulfapyridine, and low-dose methotrexate therapy in a patient with rheumatoid arthritis.

Okada, Fumi / Fukushi, Jun-Ichi / Matsubara, Hirokazu / Ishitani, Ei-Ichi / Sonoda, Yasuo / Katsuki, Ichiro

Modern rheumatology case reports

2020 Volume 4, Issue 2, Page(s) 171–175

Abstract: Osteoarticular tuberculosis can occur in patients with rheumatoid arthritis (RA) receiving immunosuppressive therapy. Here, we describe a case of tubercular osteomyelitis in an old fused hip of a patient with RA who received prednisolone, ... ...

Abstract	Osteoarticular tuberculosis can occur in patients with rheumatoid arthritis (RA) receiving immunosuppressive therapy. Here, we describe a case of tubercular osteomyelitis in an old fused hip of a patient with RA who received prednisolone, salazosulfapyridine (SASP), and low-dose methotrexate (MTX). A 77-year-old man with a 4-year history of RA was admitted with a complaint of general fatigue. His symptoms of RA had been well controlled with a combination of prednisolone, SASP, and low-dose MTX. Because the laboratory data showed an increase in serum C-reactive protein levels, we suspected pneumonia. There was expansion of a pre-existing consolidation in the right lower lobe of his lung on chest computed tomography, and the sputum culture was positive for
MeSH term(s)	Aged ; Antirheumatic Agents/administration & dosage ; Antirheumatic Agents/adverse effects ; Antirheumatic Agents/therapeutic use ; Antitubercular Agents/therapeutic use ; Arthritis, Rheumatoid/complications ; Arthritis, Rheumatoid/drug therapy ; Drug Therapy, Combination ; Humans ; Immunosuppressive Agents/administration & dosage ; Immunosuppressive Agents/adverse effects ; Immunosuppressive Agents/therapeutic use ; Male ; Methotrexate/administration & dosage ; Osteomyelitis/diagnosis ; Osteomyelitis/drug therapy ; Osteomyelitis/etiology ; Prednisolone/administration & dosage ; Sulfasalazine/administration & dosage ; Treatment Outcome ; Tuberculosis, Osteoarticular/diagnosis ; Tuberculosis, Osteoarticular/drug therapy ; Tuberculosis, Osteoarticular/etiology
Chemical Substances	Antirheumatic Agents ; Antitubercular Agents ; Immunosuppressive Agents ; Sulfasalazine (3XC8GUZ6CB) ; Prednisolone (9PHQ9Y1OLM) ; Methotrexate (YL5FZ2Y5U1)
Language	English
Publishing date	2020-03-13
Publishing country	England
Document type	Case Reports ; Journal Article
ISSN	2472-5625
ISSN (online)	2472-5625
DOI	10.1080/24725625.2020.1739194
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Article: Anterolateral rotatory instability

Tashiro, Yasutaka / Okazaki, Ken / Murakami, Koji / Matsubara, Hirokazu / Osaki, Kanji / Iwamoto, Yukihide / Nakashima, Yasuharu

World journal of orthopedics

2017 Volume 8, Issue 12, Page(s) 913–921

Abstract: Aim: To quantitatively assess rotatory and anterior-posterior instability : Methods: Single-bundle ACL reconstruction with BTB autograft was performed on 50 patients with a mean age of 28 years using the trans-tibial (TT) (: Results: A total of 40 ...

Abstract	Aim: To quantitatively assess rotatory and anterior-posterior instability Methods: Single-bundle ACL reconstruction with BTB autograft was performed on 50 patients with a mean age of 28 years using the trans-tibial (TT) ( Results: A total of 40 patients (80%) were finally followed up. Femoral tunnel positions were shallower ( Conclusion: Anterolateral rotatory instability significantly correlated shallow femoral tunnel positions after ACL reconstruction using BTB autografts. Clinical outcomes, rotatory and anterior-posterior stability were overall satisfactory in both techniques, but the TT technique located femoral tunnels in shallower and higher positions, and tibial tunnels in more posterior positions than the TP technique, thus increased the anterolateral rotation. Anatomic ACL reconstruction with BTB autografts may restore knee function and stability.
Language	English
Publishing date	2017-12-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	2649712-8
ISSN	2218-5836
ISSN	2218-5836
DOI	10.5312/wjo.v8.i12.913
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Article ; Online: Overestimation of femoral tunnel length during anterior cruciate ligament reconstruction using the retrograde outside-in drilling technique.

Okazaki, Ken / Osaki, Kanji / Nishikawa, Kazutaka / Matsubara, Hirokazu / Tashiro, Yasutaka / Iwamoto, Yukihide

Archives of orthopaedic and trauma surgery

2016 Volume 136, Issue 8, Page(s) 1159–1163

Abstract: Purpose: When the femoral tunnel socket is reamed in an oblique direction from the wall of inter-condylar notch in anterior cruciate ligament (ACL) reconstruction, the tunnel length can be shorter at the periphery than at the centre. Because surgeons ... ...

Abstract	Purpose: When the femoral tunnel socket is reamed in an oblique direction from the wall of inter-condylar notch in anterior cruciate ligament (ACL) reconstruction, the tunnel length can be shorter at the periphery than at the centre. Because surgeons can manipulate the direction of tunnel in the outside-in femoral tunnel drilling technique, this length mismatch would vary depending on the direction of the tunnel. The purpose of this study was to investigate this length mismatch when reamed in various directions. Methods: In total of thirteen points were defined as femoral drilling entry points on concentric lines with 0, 1, 2, and 3 cm radius from the lateral epicondyle of a three-dimensional bone model from 40 subjects. Femoral tunnel drilling was simulated on the models by connecting the centre of the ACL footprint with each defined point on the lateral femoral surface. The mismatch length was measured between the centre and the shortest peripheral side of the tunnel socket. Results: When the distance between the drilling entry point on the lateral femoral surface and the lateral epicondyle was increased to anterior proximal direction, there was a significant increase in the mismatch length. The mismatch length became more than 2 mm when the entry point was located more than 2 cm away from the lateral epicondyle. Conclusions: When the drilling entry point is set far away from the lateral epicondyle, a significant increase was observed in tunnel length mismatch between the centre of the tunnel and its shortest peripheral side. Because the tunnel length is measured with a guide pin introduced at the centre of the tunnel before reaming in retrograde outside-in technique, this length mismatch could cause an overestimation of the tunnel length. Surgeons should recognise this mismatch when preparing the length of graft and socket to optimise the graft insertion length into the socket.
MeSH term(s)	Adolescent ; Adult ; Anterior Cruciate Ligament Reconstruction/methods ; Female ; Femur/diagnostic imaging ; Femur/surgery ; Humans ; Imaging, Three-Dimensional ; Male ; Middle Aged ; Models, Biological ; Osteotomy ; Young Adult
Language	English
Publishing date	2016-08
Publishing country	Germany
Document type	Journal Article
ZDB-ID	80407-1
ISSN	1434-3916 ; 0003-9330 ; 0344-8444
ISSN (online)	1434-3916
ISSN	0003-9330 ; 0344-8444
DOI	10.1007/s00402-016-2492-y
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Article ; Online: Influences of knee flexion angle and portal position on the location of femoral tunnel outlet in anterior cruciate ligament reconstruction with anteromedial portal technique.

Osaki, Kanji / Okazaki, Ken / Tashiro, Yasutaka / Matsubara, Hirokazu / Iwamoto, Yukihide

Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA

2013 Volume 23, Issue 3, Page(s) 777–784

Abstract: Purpose: To evaluate the influences of knee flexion angle and portal position on the location of femoral tunnel outlet in anterior cruciate ligament (ACL) reconstruction with the anteromedial (AM) portal technique.: Methods: We recruited 6 volunteers ...

Abstract	Purpose: To evaluate the influences of knee flexion angle and portal position on the location of femoral tunnel outlet in anterior cruciate ligament (ACL) reconstruction with the anteromedial (AM) portal technique. Methods: We recruited 6 volunteers with 12 normal knees. Each knee was flexed 120° or 135° and scanned with an open MRI. A 3D knee model was created. Virtual femoral tunnels were created on the footprint of the AM bundle and the posterolateral (PL) bundle of the ACL from three arthroscopic portals: the standard AM portal, the far medial and low portal, and the far medial and high (FMH) portal. The location of the femoral tunnel outlet was evaluated by comparing to the dissected cadaveric knee. Results: Both increased flexion angle and lowering the drilling portal have a similar influence on the femoral tunnel outlet by moving them anterior and distally. Medialization of the portal moves them posteriorly and distally. PL tunnels created on the 120° knee model are more likely to be located under the lateral head of the gastrocnemius especially when they are drilled through the AM or FMH portals. Conclusion: If the femoral tunnel outlet is located under the soft tissue such as gastrocnemius attachment, suspension fixation devices may lapse into fixation failure by sitting on the soft tissue rather than the cortex bone surface. It is more desirable to drill in 135° knee flexion rather than 120°, and through a lower portal, to avoid creating the femoral tunnel outlet under soft tissues.
MeSH term(s)	Adult ; Anterior Cruciate Ligament/surgery ; Anterior Cruciate Ligament Reconstruction/methods ; Arthroscopy ; Female ; Femur/surgery ; Humans ; Knee Joint/physiology ; Knee Joint/surgery ; Magnetic Resonance Imaging ; Male ; Posture ; Range of Motion, Articular
Language	English
Publishing date	2013-10-09
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1159064-6
ISSN	1433-7347 ; 0942-2056
ISSN (online)	1433-7347
ISSN	0942-2056
DOI	10.1007/s00167-013-2705-7
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Article ; Online: Detection of early cartilage deterioration associated with meniscal tear using T1ρ mapping magnetic resonance imaging.

Matsubara, Hirokazu / Okazaki, Ken / Takayama, Yukihisa / Osaki, Kanji / Matsuo, Yoshio / Honda, Hiroshi / Iwamoto, Yukihide

BMC musculoskeletal disorders

2015 Volume 16, Page(s) 22

Abstract: Background: In patients with degenerative meniscal tears, subclinical cartilage degeneration may be present even if gross morphological changes are not evident. The aim of this study was to detect occult cartilage degeneration using T1ρ MRI mapping in ... ...

Abstract	Background: In patients with degenerative meniscal tears, subclinical cartilage degeneration may be present even if gross morphological changes are not evident. The aim of this study was to detect occult cartilage degeneration using T1ρ MRI mapping in patients with meniscal tears without obvious radiographic osteoarthritis (OA). Methods: A total of 22 subjects with degenerative meniscal tears in the early stages of osteoarthritis [Kellgren-Lawrence (KL) grade of 0-2] and 19 healthy subjects as the control group were examined. The femoral condyle was divided into four 30° wedges (-30°-0° anteriorly, 0°-30°, 30°-60° and 60°-90° posteriorly), and each area of cartilage was further divided into superficial and deep layers of equal thickness. The tibial side was divided into anterior and posterior areas with superficial and deep layers in each. The mean T1ρ values (ms) in each area were calculated. Results: On the femoral side, T1ρ values of the superficial and deep regions (-30°-0°, 0°-30° and 30°-60°) in the meniscal tear group were significantly higher than those in the control group [superficial (-30°-0°): 49.0 ± 4.0 (meniscal tear group) vs 45.1 ± 2.1 (control group), deep (-30°-0°): 45.2 ± 3.3 vs 39.5 ± 5.0, superficial (0°-30°): 54.5 ± 5.3 vs 47.4 ± 5.7, deep (0°-30°): 46.8 ± 4.0 vs 40.7 ± 6.3, superficial (30°-60°): 50.5 ± 3.1 vs 47.1 ± 5.7]. On the tibial side, the meniscal tear group had significantly higher T1ρ values superficially in both anterior and posterior regions compared with the control group [superficial (anterior): 52.0 ± 4.3 vs 46.7 ± 5.4, superficial (posterior): 53.1 ± 5.1 vs 46.0 ± 4.9]. Moreover, these significant differences were observed when comparing patients in the meniscal tear group with KL grades of 0 or 1 and the control group. Conclusions: Our study suggested that early biochemical changes in cartilage associated with degenerative meniscal tears occur first in the superficial zones in areas of contact during slight flexion. Characterising the early relationship between cartilage degeneration and degenerative meniscal tears using T1ρ MRI mapping may be of clinical benefit and provide further evidence linking meniscal injury to OA.
MeSH term(s)	Adult ; Aged ; Cartilage, Articular/pathology ; Case-Control Studies ; Female ; Humans ; Knee Injuries/complications ; Knee Injuries/pathology ; Magnetic Resonance Imaging/methods ; Male ; Middle Aged ; Osteoarthritis, Knee/etiology ; Risk Factors ; Tibial Meniscus Injuries
Language	English
Publishing date	2015-02-10
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1471-2474
ISSN (online)	1471-2474
DOI	10.1186/s12891-015-0487-4
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Article ; Online: Asymmetry in Femoral Tunnel Socket Length During Anterior Cruciate Ligament Reconstruction With Transportal, Outside-In, and Modified Transtibial Techniques.

Osaki, Kanji / Okazaki, Ken / Matsubara, Hirokazu / Kuwashima, Umito / Murakami, Koji / Iwamoto, Yukihide

Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association

2015 Volume 31, Issue 12, Page(s) 2365–2370

Abstract: Purpose: To investigate the mismatch between the length at the center and the length on the shortest and longest peripheral sides of the femoral tunnel socket, reamed with the transportal (TP), outside-in (OI), and modified transtibial (TT) techniques, ... ...

Abstract	Purpose: To investigate the mismatch between the length at the center and the length on the shortest and longest peripheral sides of the femoral tunnel socket, reamed with the transportal (TP), outside-in (OI), and modified transtibial (TT) techniques, in anterior cruciate ligament (ACL) reconstruction. Methods: Femoral tunnel drilling was simulated on 3-dimensional bone models from 40 subjects. The tunnel directions used with the TP, OI, and modified TT techniques were previously described. By use of the resulting angle, a femoral tunnel socket of 9 mm in diameter was drilled from the center of the femoral ACL insertion. The virtual femoral tunnel was extracted, and the length mismatch was measured between the center and the shortest and longest peripheral sides of the tunnel socket. Results: The mean socket length mismatch between the center and the shortest peripheral part of the femoral tunnel socket was 4.2 ± 0.9 mm with the TP technique, 5.2 ± 1.3 mm with the OI technique, and 3.2 ± 0.8 mm with the modified TT technique. The mean socket length mismatch between the center and the longest peripheral part of the femoral tunnel socket was 3.5 ± 0.9 mm with the TP technique, 4.8 ± 1.5 mm with the OI technique, and 3.3 ± 1.2 mm with the modified TT technique. The length mismatch was significantly higher when the tunnel socket was created by the OI technique (P < .01). Conclusions: A length mismatch with the tunnel socket exists after reaming with either the TP, OI, or modified TT technique. In particular, there was a significant increase in length mismatch when the tunnel socket was created by the OI technique, and the length mismatch would easily become greater than 5 mm. The surgeon should recognize this mismatch when it is created and measure the femoral tunnel socket. Clinical relevance: In anatomic ACL reconstruction, a mismatch between the length at the center and the length at periphery of the femoral tunnel socket occurs, and this is increased particularly when using the OI technique. The discrepancy in tunnel length between its center and its periphery could cause an overestimation of the tunnel length that could result in an error in length during graft preparation.
MeSH term(s)	Adolescent ; Adult ; Anterior Cruciate Ligament/surgery ; Anterior Cruciate Ligament Injuries ; Anterior Cruciate Ligament Reconstruction/methods ; Female ; Femur/surgery ; Humans ; Knee Joint/surgery ; Male ; Middle Aged ; Tibia/surgery ; Tomography, X-Ray Computed/methods ; Young Adult
Language	English
Publishing date	2015-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	632528-2
ISSN	1526-3231 ; 0749-8063
ISSN (online)	1526-3231
ISSN	0749-8063
DOI	10.1016/j.arthro.2015.06.026
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Article ; Online: Intercondylar roof impingement after anatomic double-bundle anterior cruciate ligament reconstruction in patients with knee hyperextension.

Matsubara, Hirokazu / Okazaki, Ken / Tashiro, Yasutaka / Toyoda, Kazutaka / Uemura, Munenori / Hashizume, Makoto / Iwamoto, Yukihide

The American journal of sports medicine

2013 Volume 41, Issue 12, Page(s) 2819–2827

Abstract: Background: Although an anatomically placed graft in anterior cruciate ligament (ACL) reconstruction is reported to have a low risk of roof impingement, which may cause deterioration of the graft or an extension deficit, the incidence of roof ... ...

Abstract	Background: Although an anatomically placed graft in anterior cruciate ligament (ACL) reconstruction is reported to have a low risk of roof impingement, which may cause deterioration of the graft or an extension deficit, the incidence of roof impingement by these grafts has not been evaluated in hyperextensible knees. Purpose: To evaluate the incidence of roof impingement by the native ACL in hyperextensible knees and to examine the risk of roof impingement by anatomic placement of the ACL graft in hyperextensible knees. Study design: Controlled laboratory study. Methods: Twelve patients were selected for a hyperextensible knee group (group A), defined as having hyperextension of the knee of greater than 10°. Twelve patients were recruited to a normal extension knee group (group B) with normal extension of the knee of less than 5° of hyperextension. Magnetic resonance imaging (MRI) scans of the knee positioned in 30° of flexion and full extension were acquired from all patients. The shape of the native ACL at full extension was compared between the groups. A 3-dimensional (3D) bone model was created from the acquired 2D MRI scans. A virtual anatomic double-bundle ACL reconstruction in each patient and a virtual anatomic single-bundle reconstruction in the patients in group A were performed using the 3D MRI bone models. The volume of the overlap between the graft and roof was calculated to evaluate graft impingement in each instance. Results: The MRI scans showed posterior bowing of the native ACL in the group A knees. The simulated double-bundle ACL reconstruction showed that the overlapped volume was significantly greater in patients in group A than in patients in group B (P < .05). However, the overlap of the simulated single-bundle ACL reconstruction was significantly less than for the double-bundle ACL reconstruction (P < .05). Conclusion: To reduce the risk of roof impingement by the graft, single-bundle ACL reconstruction with the graft placed at the center of the footprint might be the better method for patients with a hyperextensible knee than an anatomic double-bundle ACL reconstruction. Clinical relevance: It is recommended that surgeons cautiously consider roof impingement after anatomic double-bundle ACL reconstruction in patients with a hyperextensible knee.
MeSH term(s)	Adolescent ; Adult ; Anterior Cruciate Ligament/surgery ; Anterior Cruciate Ligament Reconstruction/adverse effects ; Female ; Humans ; Image Processing, Computer-Assisted ; Joint Diseases/etiology ; Knee Injuries/surgery ; Knee Joint/surgery ; Magnetic Resonance Imaging/methods ; Male ; Middle Aged ; Postoperative Complications ; Range of Motion, Articular ; Young Adult
Language	English
Publishing date	2013-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	197482-8
ISSN	1552-3365 ; 0363-5465
ISSN (online)	1552-3365
ISSN	0363-5465
DOI	10.1177/0363546513505073
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Article: Characterization of Biochemical Cartilage Change After Anterior Cruciate Ligament Injury Using T1ρ Mapping Magnetic Resonance Imaging.

Osaki, Kanji / Okazaki, Ken / Takayama, Yukihisa / Matsubara, Hirokazu / Kuwashima, Umito / Murakami, Koji / Doi, Toshio / Matsuo, Yoshio / Honda, Hiroshi / Iwamoto, Yukihide

Orthopaedic journal of sports medicine

2015 Volume 3, Issue 5, Page(s) 2325967115585092

Abstract: Background: Patients with anterior cruciate ligament (ACL)-injured knees are at an increased risk of posttraumatic osteoarthritis (OA). OA changes secondary to ACL injuries have many variations, and when and where early cartilage degenerative change ... ...

Abstract	Background: Patients with anterior cruciate ligament (ACL)-injured knees are at an increased risk of posttraumatic osteoarthritis (OA). OA changes secondary to ACL injuries have many variations, and when and where early cartilage degenerative change begins has not yet been established. Purpose: To characterize the location of cartilage degeneration after ACL injury associated with time since injury using T1rho (T1ρ) mapping. Study design: Cross-sectional study; Level of evidence, 3. Methods: In this study, 49 knees with ACL injuries and 14 normal knees from uninjured volunteers were imaged with a 3.0-T magnetic resonance scanner. Three regions of interest (ROIs) were defined in the cartilage at the weightbearing area of the femoral condyles (anterior, middle, and posterior zones). Two ROIs were defined in the tibial plateau (anterior and posterior zones). The T1ρ values within the ROIs were measured. Patients were allocated into 3 groups based on time since injury: <12 weeks (group A; 28 patients), 12 weeks to 2 years (group B; 14 patients), and >2 years to 5 years (group C; 7 patients). Results: Mean T1ρ values were significantly greater in the anterior and middle ROIs of the medial femoral condyle in group C compared with those in other groups (P < .05). Patients with medial meniscus injury, for whom the time since injury was ≥12 weeks, exhibited significantly greater T1ρ values in the middle areas of the medial femoral condyle versus normal knees and ACL-injured knees without medial meniscus injury. Conclusion: The risk of cartilage degeneration in the area of the femoral condyle that contacts the tibia during small degrees of flexion increased when the time since injury was longer than 2 years. In addition, medial meniscus injury was associated with cartilage degeneration at the medial femoral condyle in the chronic phase. Clinical relevance: Cartilage degeneration occurs more than 2 years after ACL injury and increases with medial meniscus injury. Early intervention may be desirable for meniscus injury.
Language	English
Publishing date	2015-05-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	2706251-X
ISSN	2325-9671
ISSN	2325-9671
DOI	10.1177/2325967115585092
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