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  1. Article ; Online: Studies of Local DNA Backbone Conformation and Conformational Disorder Using Site-Specific Exciton-Coupled Dimer Probe Spectroscopy.

    Marcus, Andrew H / Heussman, Dylan / Maurer, Jack / Albrecht, Claire S / Herbert, Patrick / von Hippel, Peter H

    Annual review of physical chemistry

    2023  Volume 74, Page(s) 245–265

    Abstract: The processes of genome expression, regulation, and repair require direct interactions between proteins and DNA at specific sites located at and near single-stranded-double-stranded DNA (ssDNA-dsDNA) junctions. Here, we review the application of recently ...

    Abstract The processes of genome expression, regulation, and repair require direct interactions between proteins and DNA at specific sites located at and near single-stranded-double-stranded DNA (ssDNA-dsDNA) junctions. Here, we review the application of recently developed spectroscopic methods and analyses that combine linear absorbance and circular dichroism spectroscopy with nonlinear 2D fluorescence spectroscopy to study the local conformations and conformational disorder of the sugar-phosphate backbones of ssDNA-dsDNA fork constructs that have been internally labeled with exciton-coupled cyanine (iCy3)
    MeSH term(s) DNA/chemistry ; Nucleic Acid Conformation ; DNA, Single-Stranded ; Spectrometry, Fluorescence ; Phosphates ; Sugars
    Chemical Substances DNA (9007-49-2) ; DNA, Single-Stranded ; Phosphates ; Sugars
    Language English
    Publishing date 2023-01-25
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, N.I.H., Extramural
    ZDB-ID 1470474-2
    ISSN 1545-1593 ; 0066-426X
    ISSN (online) 1545-1593
    ISSN 0066-426X
    DOI 10.1146/annurev-physchem-090419-041204
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Studies of DNA 'Breathing' by Polarization-Sweep Single-Molecule Fluorescence Microscopy of Exciton-Coupled (iCy3)

    Maurer, Jack / Albrecht, Claire S / Herbert, Patrick / Heussman, Dylan / Chang, Anabel / von Hippel, Peter H / Marcus, Andrew H

    The journal of physical chemistry. B

    2023  Volume 127, Issue 50, Page(s) 10730–10748

    Abstract: Local fluctuations of the sugar-phosphate backbones and bases of DNA (often called DNA 'breathing') play a variety of critical roles in controlling the functional interactions of the DNA genome with the protein complexes that regulate it. Here, we ... ...

    Abstract Local fluctuations of the sugar-phosphate backbones and bases of DNA (often called DNA 'breathing') play a variety of critical roles in controlling the functional interactions of the DNA genome with the protein complexes that regulate it. Here, we present a single-molecule fluorescence method that we have used to measure and characterize such conformational fluctuations at and near biologically important positions in model DNA replication fork constructs labeled with exciton-coupled cyanine [(iCy3)
    MeSH term(s) DNA/metabolism ; Molecular Conformation ; DNA Replication ; Spectrometry, Fluorescence ; Microscopy, Fluorescence
    Chemical Substances DNA (9007-49-2)
    Language English
    Publishing date 2023-12-07
    Publishing country United States
    Document type Journal Article
    ISSN 1520-5207
    ISSN (online) 1520-5207
    DOI 10.1021/acs.jpcb.3c06463
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Spectroscopic approaches for studies of site-specific DNA base and backbone 'breathing' using exciton-coupled dimer-labeled DNA.

    Marcus, Andrew H / Matsika, Spiridoula / Heussman, Dylan / Sorour, Mohammed I / Maurer, Jack / Albrecht, Claire S / Enkhbaatar, Lulu / Herbert, Patrick / Kistler, Kurt A / von Hippel, Peter H

    ArXiv

    2024  

    Abstract: DNA regulation and repair processes require direct interactions between proteins and DNA at specific sites. Local fluctuations of the sugar-phosphate backbones and bases of DNA (a form of DNA 'breathing') play a central role in such processes. Here we ... ...

    Abstract DNA regulation and repair processes require direct interactions between proteins and DNA at specific sites. Local fluctuations of the sugar-phosphate backbones and bases of DNA (a form of DNA 'breathing') play a central role in such processes. Here we review the development and application of novel spectroscopic methods and analyses - both at the ensemble and single-molecule levels - to study structural and dynamic properties of exciton-coupled cyanine and fluorescent nucleobase analogue dimer-labeled DNA constructs at key positions involved in protein-DNA complex assembly and function. The exciton-coupled dimer probes act as 'sensors' of the local conformations adopted by the sugar-phosphate backbones and bases immediately surrounding the dimer probes. These methods can be used to study the mechanisms of protein binding and function at these sites.
    Language English
    Publishing date 2024-03-27
    Publishing country United States
    Document type Preprint
    ISSN 2331-8422
    ISSN (online) 2331-8422
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book ; Conference proceedings: Heat exchanger technologies for the global environment

    Maurer, Jack R

    presented at the 1994 International Joint Power Generation Conference, Phoenix, Arizona, October 2-6, 1994

    (PWR ; 25)

    1994  

    Institution American Society of Mechanical Engineers / Power Division
    International Joint Power Generation Conference
    Event/congress International Joint Power Generation Conference (1994, 1994.10.02-06, PhoenixAriz.)
    Author's details sponsored by the Power Division, ASME
    Series title PWR ; 25
    Keywords Heat exchangers/Congresses
    Language English
    Size V, 173 S, ill
    Publisher American Society of Mechanical Engineers
    Publishing place New York, NY
    Document type Book ; Conference proceedings
    Note Includes bibliographical references and index
    ISBN 0791813819 ; 9780791813812
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  5. Book ; Conference proceedings: Developments in the power industry

    Maurer, Jack R

    heat exchanger technologies and materials ; presented at The 1993 International Joint Power Generation Conference Kansas City, Missouri October 17 - 22, 1993

    (PWR ; 23)

    1993  

    Institution American Society of Mechanical Engineers / Power Division
    International Joint Power Generation Conference
    Event/congress International Joint Power Generation Conference (1993.10.17-22, KansasCityM.)
    Author's details sponsored by The Power Division, ASME. Ed. by Jack R. Maurer
    Series title PWR ; 23
    Keywords Heat exchangers/Congresses
    Language English
    Size V, 115 S, Ill., graph Darst
    Publisher ASME
    Publishing place New York
    Document type Book ; Conference proceedings
    ISBN 0791809986 ; 9780791809983
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  6. Book ; Conference proceedings: Practical aspects and performance of heat exchanger components and materials

    Maurer, Jack R

    presented at the 1992 International Joint Power Generation Conference, Atlanta, Georga, October 18 - 22, 1992

    (PWR ; vol. 19)

    1992  

    Institution American Society of Mechanical Engineers / Power Division
    International Joint Power Generation Conference
    Event/congress International Joint Power Generation Conference (JPGC) (1992, 1992.10.18-22, AtlantaGa.)
    Author's details sponsored by the Power Division, ASME. Ed. by Jack R. Maurer
    Series title PWR ; vol. 19
    Keywords Heat exchangers/Congresses
    Language English
    Size v, 119 p, ill, 28 cm
    Publisher American Society of Mechanical Engineers
    Publishing place New York
    Document type Book ; Conference proceedings
    Note Includes bibliographical references and index
    ISBN 0791807959 ; 9780791807958
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  7. Book ; Conference proceedings: Practical aspects and performance of heat exchanger components and materials

    Maurer, Jack R

    presented at the 1991 International Joint Power Generation Conference

    (PWR ; 14)

    1991  

    Institution American Society of Mechanical Engineers / Power Division
    Event/congress International Joint Power Generation Conference (JPGC) ^[part (1991, 1991.10.06-10, SanDiegoCalif.)
    Author's details sponsored by the Heat Exchanger Committee of the Power Division, ASME; edited by Jack R. Maurer
    Series title PWR ; 14
    Keywords Heat exchangers/Congresses
    Language English
    Size v, 61 p, ill, 28 cm
    Publisher American Society of Mechanical Engineers
    Publishing place New York, N.Y
    Document type Book ; Conference proceedings
    Note Committee's 3. volume and the 11. year sponsoring sessions at the JPGC. - Includes bibliographical references and index
    ISBN 0791808211 ; 9780791808214
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  8. Book ; Conference proceedings: Performance monitoring and replacement of heat exchanger components and materials

    Maurer, Jack R

    papers

    (PWR ; 12)

    1990  

    Institution American Society of Mechanical Engineers (ASME) / Power Division
    Event/congress International Joint Power Generation Conference (JPGC) ^[part (1990, 1990.10.21-25, BostonMass.)
    Author's details sponsored by the Heat Exchanger Committee, the Power Division, ASME; edited by Jack R. Maurer
    Series title PWR ; 12
    Keywords Heat exchangers/Congresses
    Language English
    Size v, 63 p, ill, 28 cm
    Publisher ASME
    Publishing place New York, N.Y
    Document type Book ; Conference proceedings
    Note Committee's 2. volume. - Includes bibliographical references
    ISBN 0791805328 ; 9780791805329
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  9. Book ; Conference proceedings: Improved performance of heat exchanger systems through design, condition management and auxiliary interaction

    Maurer, Jack R

    Session papers

    (PWR ; 6)

    1989  

    Institution American Society of Mechanical Engineers / Power Division
    Event/congress Joint Power Generation Conference ^[Part (1989, 1989.10.22-26, DallasTex.)
    Author's details Jack R. Maurer [Hrsg.]. American Society of Mechanical Engineers / Power Division / Heat Exchanger Committee; American Society of Mechanical Engineers / Power Division / Steam Turbine and Related Auxiliaries Committee
    Series title PWR ; 6
    Size V, 58 S
    Publisher ASME
    Publishing place New York
    Document type Book ; Conference proceedings
    ISBN 0791803805 ; 9780791803806
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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