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  1. Book: Acrodermatitis Enteropathica

    Beigi, Pooya Khan Mohammad / Maverakis, Emanual

    a clinician's guide

    2015  

    Author's details Pooya Khan Mohammad Beigi ; Emanual Maverakis
    Keywords acrodermatitis ; dermatology ; epidemiology ; Brandt syndrome ; pediatrics ; obstetrics
    Language English
    Size XXI, 156 S. : zahlr. Ill., graph. Darst., 235 mm x 155 mm
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT018722696
    ISBN 978-3-319-17818-9 ; 3-319-17818-0 ; 9783319178196 ; 3319178199
    Database Catalogue ZB MED Medicine, Health

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  2. Article: Maintaining and Restoring Gradients of Ions in the Epidermis: The Role of Ion and Water Channels in Acute Cutaneous Wound Healing.

    Mai, Kevin / Maverakis, Emanual / Li, Jung / Zhao, Min

    Advances in wound care

    2023  Volume 12, Issue 12, Page(s) 696–709

    Abstract: Significance: ...

    Abstract Significance:
    MeSH term(s) Water ; Epidermis ; Wound Healing/physiology ; Ion Channels ; Aquaporins
    Chemical Substances Water (059QF0KO0R) ; Ion Channels ; Aquaporins
    Language English
    Publishing date 2023-06-06
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2650541-1
    ISSN 2162-1934 ; 2162-1918
    ISSN (online) 2162-1934
    ISSN 2162-1918
    DOI 10.1089/wound.2022.0128
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Support Group Participation Among Patients With Alopecia Areata.

    Haughton, Reneé / Herbert, Samantha / Meyer, Summer / Kam, Olivia / Maverakis, Emanual / Kiuru, Maija

    JAMA dermatology

    2024  Volume 160, Issue 3, Page(s) 358–360

    MeSH term(s) Humans ; Alopecia Areata ; Self-Help Groups
    Language English
    Publishing date 2024-02-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2701761-8
    ISSN 2168-6084 ; 2168-6068
    ISSN (online) 2168-6084
    ISSN 2168-6068
    DOI 10.1001/jamadermatol.2023.6037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Targeting interleukin-5 with benralizumab: A novel treatment for drug rash with eosinophilia and systemic symptoms.

    Maverakis, Emanual / Ji-Xu, Antonio / Brüggen, Marie-Charlotte

    Allergy

    2022  Volume 77, Issue 8, Page(s) 2287–2289

    MeSH term(s) Anti-Asthmatic Agents/adverse effects ; Antibodies, Monoclonal, Humanized/adverse effects ; Eosinophilia/drug therapy ; Exanthema/drug therapy ; Humans ; Interleukin-5
    Chemical Substances Anti-Asthmatic Agents ; Antibodies, Monoclonal, Humanized ; Interleukin-5 ; benralizumab (71492GE1FX)
    Language English
    Publishing date 2022-03-08
    Publishing country Denmark
    Document type Editorial
    ZDB-ID 391933-x
    ISSN 1398-9995 ; 0105-4538
    ISSN (online) 1398-9995
    ISSN 0105-4538
    DOI 10.1111/all.15283
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Janus kinase inhibitors and risk of internal malignancy in dermatomyositis.

    Ji-Xu, Antonio / Le, Stephanie T / Maverakis, Emanual

    The Journal of dermatological treatment

    2022  Volume 33, Issue 6, Page(s) 2881–2882

    MeSH term(s) Humans ; Janus Kinase Inhibitors/adverse effects ; Dermatomyositis/drug therapy ; Pyrazoles ; Pyrimidines ; Neoplasms/etiology
    Chemical Substances Janus Kinase Inhibitors ; Pyrazoles ; Pyrimidines
    Language English
    Publishing date 2022-06-16
    Publishing country England
    Document type Letter
    ZDB-ID 1036299-x
    ISSN 1471-1753 ; 0954-6634
    ISSN (online) 1471-1753
    ISSN 0954-6634
    DOI 10.1080/09546634.2022.2089323
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Factors associated with impaired quality of life and support group utilization in autoimmune bullous disease.

    Herbert, Samantha / Haughton, Renee / Artounian, Kimberly / Downing, Lauren / Ji-Xu, Antonio / Maverakis, Emanual

    Journal of the American Academy of Dermatology

    2023  Volume 89, Issue 4, Page(s) 813–815

    MeSH term(s) Humans ; Quality of Life ; Autoimmune Diseases ; Pemphigus
    Language English
    Publishing date 2023-06-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603641-7
    ISSN 1097-6787 ; 0190-9622
    ISSN (online) 1097-6787
    ISSN 0190-9622
    DOI 10.1016/j.jaad.2023.05.062
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Interleukin-23 Regulates Inflammatory Osteoclastogenesis via Activation of CLEC5A(+) Osteoclast Precursors.

    Furuya, Hiroki / Nguyen, Cuong Thach / Gu, Ran / Hsieh, Shie-Liang / Maverakis, Emanual / Adamopoulos, Iannis E

    Arthritis & rheumatology (Hoboken, N.J.)

    2023  Volume 75, Issue 8, Page(s) 1477–1489

    Abstract: Objective: To investigate the role of interleukin-23 (IL-23) in pathologic bone remodeling in inflammatory arthritis.: Methods: In this study we investigated the role of IL-23 in osteoclast differentiation and activation using in vivo gene transfer ... ...

    Abstract Objective: To investigate the role of interleukin-23 (IL-23) in pathologic bone remodeling in inflammatory arthritis.
    Methods: In this study we investigated the role of IL-23 in osteoclast differentiation and activation using in vivo gene transfer techniques in wild-type and myeloid DNAX-activation protein 12-associating lectin-1 (MDL-1)-deficient mice, and by performing in vitro and in vivo osteoclastogenesis assays using spectral flow cytometry, micro-computed tomography analysis, Western blotting, and immunoprecipitation.
    Results: Herein, we show that IL-23 induces the expansion of a myeloid osteoclast precursor population and supports osteoclastogenesis and bone resorption in inflammatory arthritis. Genetic ablation of C-type lectin domain family member 5A, also known as MDL-1, prevents the induction of osteoclast precursors by IL-23 that is associated with bone destruction, as commonly observed in inflammatory arthritis. Moreover, osteoclasts derived from the bone marrow of MDL-1-deficient mice showed impaired osteoclastogenesis, and MDL-1
    Conclusion: Our data show that IL-23 signaling regulates the availability of osteoclast precursors in inflammatory arthritis that could be effectively targeted for the treatment of inflammatory bone loss in inflammatory arthritis.
    MeSH term(s) Mice ; Animals ; Osteoclasts/metabolism ; Osteogenesis ; Interleukin-23 ; X-Ray Microtomography ; Bone Resorption/metabolism ; Arthritis/pathology ; Cell Differentiation ; RANK Ligand/metabolism
    Chemical Substances Interleukin-23 ; RANK Ligand
    Language English
    Publishing date 2023-06-06
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2756371-6
    ISSN 2326-5205 ; 2326-5191
    ISSN (online) 2326-5205
    ISSN 2326-5191
    DOI 10.1002/art.42478
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: A review of topical probiotic therapy for atopic dermatitis.

    Herbert, Samantha / Haughton, Reneé / Nava, Jordan / Ji-Xu, Antonio / Le, Stephanie T / Maverakis, Emanual

    Clinical and experimental dermatology

    2023  Volume 48, Issue 4, Page(s) 319–324

    Abstract: Atopic dermatitis (AD) is a common, chronic skin disorder that is associated with dysbiosis of the skin microbiome along with an impaired skin barrier and abnormal immune signalling. Particularly, AD has been associated with increased abundance of ... ...

    Abstract Atopic dermatitis (AD) is a common, chronic skin disorder that is associated with dysbiosis of the skin microbiome along with an impaired skin barrier and abnormal immune signalling. Particularly, AD has been associated with increased abundance of Staphylococcus aureus and decreased overall bacterial diversity. Topical probiotic formulations are garnering further interest in the treatment of AD and may be derived from commensal bacteria found on healthy epithelium or from exogenous bacteria. Strains chosen for clinical trials have often demonstrated antimicrobial actions to S. aureus in vitro. Multiple randomized clinical trials with topical probiotics have resulted in significant improvements in clinical severity, decreased abundance of S. aureus in treated lesional skin and increased bacterial diversity. Side-effects from available studies have been minimal apart from one patient who developed a furuncle in the treatment area. Topical probiotics have been shown to be safe and potentially efficacious in AD; however, further research including larger, longer-term clinical trials need to be performed before topical probiotics should be recommended to patients.
    MeSH term(s) Humans ; Dermatitis, Atopic/drug therapy ; Staphylococcus aureus ; Skin/microbiology ; Probiotics/therapeutic use ; Epithelium
    Language English
    Publishing date 2023-01-20
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 195504-4
    ISSN 1365-2230 ; 0307-6938
    ISSN (online) 1365-2230
    ISSN 0307-6938
    DOI 10.1093/ced/llac138
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Protein oxidation of fucose environments (POFE) reveals fucose-protein interactions.

    Xie, Yixuan / Chen, Siyu / Alvarez, Michael Russelle / Sheng, Ying / Li, Qiongyu / Maverakis, Emanual / Lebrilla, Carlito B

    Chemical science

    2024  Volume 15, Issue 14, Page(s) 5256–5267

    Abstract: Cell membrane glycoproteins are generally highly fucosylated and sialylated, and post-translational modifications play important roles in the proteins' functions of signaling, binding and cellular processing. For these reasons, methods for measuring ... ...

    Abstract Cell membrane glycoproteins are generally highly fucosylated and sialylated, and post-translational modifications play important roles in the proteins' functions of signaling, binding and cellular processing. For these reasons, methods for measuring sialic acid-mediated protein-protein interactions have been developed. However, determining the role of fucose in these interactions has been limited by technological barriers that have thus far hindered the ability to characterize and observe fucose-mediated protein-protein interactions. Herein, we describe a method to metabolically label mammalian cells with modified fucose, which incorporates a bioorthogonal group into cell membrane glycoproteins thereby enabling the characterization of cell-surface fucose interactome. Copper-catalyzed click chemistry was used to conjugate a proximity labeling probe, azido-FeBABE. Following the addition of hydrogen peroxide (H
    Language English
    Publishing date 2024-03-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2559110-1
    ISSN 2041-6539 ; 2041-6520
    ISSN (online) 2041-6539
    ISSN 2041-6520
    DOI 10.1039/d3sc06432h
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: IL-27 attenuates IL-23 mediated inflammatory arthritis.

    Sarin, Ritu / Gu, Ran / Jalali, Zahra / Maverakis, Emanual / Tsokos, Maria G / Adamopoulos, Iannis E

    Clinical immunology (Orlando, Fla.)

    2023  Volume 251, Page(s) 109327

    Abstract: Interleukin 27 has both pro-inflammatory and anti-inflammatory properties in autoimmunity. The anti-inflammatory effects of IL-27 are linked with inhibition of Th17 differentiation but the IL-27 effect on myeloid cells is less studied. Herein we ... ...

    Abstract Interleukin 27 has both pro-inflammatory and anti-inflammatory properties in autoimmunity. The anti-inflammatory effects of IL-27 are linked with inhibition of Th17 differentiation but the IL-27 effect on myeloid cells is less studied. Herein we demonstrate that IL-27 inhibits IL-23-induced inflammation associated not only with Th17 cells but also with myeloid cell infiltration in the joints and splenic myeloid populations of CD11b
    MeSH term(s) Animals ; Interleukin-27 ; Cytokines ; Arthritis, Experimental ; Inflammation ; Interleukin-23 ; Th17 Cells
    Chemical Substances Interleukin-27 ; Cytokines ; Interleukin-23
    Language English
    Publishing date 2023-04-08
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1459903-x
    ISSN 1521-7035 ; 1521-6616
    ISSN (online) 1521-7035
    ISSN 1521-6616
    DOI 10.1016/j.clim.2023.109327
    Database MEDical Literature Analysis and Retrieval System OnLINE

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