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  1. Article: Herb-Induced Liver Injury by Ayurvedic Ashwagandha as Assessed for Causality by the Updated RUCAM: An Emerging Cause.

    Bokan, Goran / Glamočanin, Tanja / Mavija, Zoran / Vidović, Bojana / Stojanović, Ana / Björnsson, Einar S / Vučić, Vesna

    Pharmaceuticals (Basel, Switzerland)

    2023  Volume 16, Issue 8

    Abstract: Herb-induced liver injury (HILI) caused by herbal supplements, natural products, and products used in traditional medicine are important for differential diagnoses in patients with acute liver injury without an obvious etiology. The root ... ...

    Abstract Herb-induced liver injury (HILI) caused by herbal supplements, natural products, and products used in traditional medicine are important for differential diagnoses in patients with acute liver injury without an obvious etiology. The root of
    Language English
    Publishing date 2023-08-10
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2193542-7
    ISSN 1424-8247
    ISSN 1424-8247
    DOI 10.3390/ph16081129
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Identification of gene candidates associated with Irritable bowel syndrome

    Milovac Irina / Vidović Vanja / Ramić Jasmin / Lojo-Kadrić Naida / Hadžić Maida / Mavija Zoran / Vidović Stojko / Pojskić Lejla

    Scripta Medica, Vol 53, Iss 4, Pp 327-

    2022  Volume 331

    Abstract: Background/Aim: Irritable bowel syndrome (IBS) belongs to the gastrointestinal disorders characterised by abdominal discomfort and pain, altered constipation, diarrhoea and stomach distension. The aim was to assess relationship between the selected ... ...

    Abstract Background/Aim: Irritable bowel syndrome (IBS) belongs to the gastrointestinal disorders characterised by abdominal discomfort and pain, altered constipation, diarrhoea and stomach distension. The aim was to assess relationship between the selected genetic polymorphisms with IBS, their combined genotype effect as well as to assess a difference in the distribution of allele and genotype frequencies of selected loci between case and control group. Methods: This was a prospective study which included 29 participants, 20 individuals diagnosed with IBS based on Rome III criteria and 9 healthy individuals. The study analysed the selected genetic polymorphisms as possible risk factors for IBS according to the model of the case-control study. Genotyping was performed for FKBP5, DRD2 and DAT polymorphisms qualified as risk factors for IBS in previous researches. Results: The results revealed a significant association between DAT polymorphism with IBS, both, at the allelic level (p = 0.006) and genotype level (p = 0.031). Individuals with 434 allelic variant in the genotype have six time higher probability for developing IBS, in comparison to the individuals without this allelic variant. The statistical association between other analysed polymorphism and IBS was not reached. The analysis of combined effects of selected polymorphisms revealed no association with IBS, except FKBP5 and DAT which result was at the level of statistical significance (p = 0.05). Conclusion: Further analysis which would include DAT polymorphism with larger sample size, as well as other genes involved in dopamine neurotransmitter system would be of great interest to define closer conclusion of IBS aetiology.
    Keywords irritable bowel syndrome ; polymorphisms ; fkbp5 ; drd2 ; dat ; Medicine ; R
    Subject code 616
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Medical Society of the Republic of Srpska, Banja Luka, University of Banja Luka. Faculty of Medicine
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Comparison of abdominal puncture and diuretics during ascites treatment

    Mavija Zoran / Mavija Milka

    Scripta Medica, Vol 45, Iss 2, Pp 51-

    2014  Volume 55

    Abstract: In clinical practice, ascites treatment is, in majority of cases, unsatisfactory and followed by multiple complications. During the therapy, some side effects, in relation to therapeutic method, may occur. The aim of the study was to compare the level of ...

    Abstract In clinical practice, ascites treatment is, in majority of cases, unsatisfactory and followed by multiple complications. During the therapy, some side effects, in relation to therapeutic method, may occur. The aim of the study was to compare the level of tolerance and effectiveness of ascites therapy in applying abdominal puncture versus diuretics between two groups of patients to establish connection and differences in applied treatments. Patients and methods. There were 60 patients examined with ascites 3+ and 4+ divided into two equal groups. First group was treated by abdominal puncture several times a week while patients in the other group were administered diuretics either monotherapeutically or in combination. Majority of patients (86.7%) experienced no side effects after applied therapeutic protocol. 6,7% of patients experienced abdominal pain, 3.3% of them had cramps, ailment 1.7% and nausea 1.7% with no statistic difference between two groups of patients (p>0.05). Registered side effects were mild (5%) to moderate (8.3%), while only 1.7% of patients treated by abdominal puncture experienced leaking of ascitic fluid at the puncture site. Conclusion. No major statistic difference between groups of patients was recorded in relation to side effects and complications in applied ascites therapy (p>0.05). Abdominal puncture and diuretics were both equally well tolerated in hospital conditions. Potential risk in ascites therapy can be reduced to the smallest possible extent by intensive observation of the patient.
    Keywords ascites ; abdominal puncture ; diuretics ; effectiveness of therapy ; Medicine ; R
    Subject code 610 ; 616
    Language English
    Publishing date 2014-01-01T00:00:00Z
    Publisher Medical Society of the Republic of Srpska, Banja Luka, University of Banja Luka. Faculty of Medicine
    Document type Article ; Online
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  4. Article ; Online: Efficacy of two different antibiotic solutions in preservation of fresh amniotic membrane

    Vesna Ljubojević, Sanja Jovičić, Milka Mavija, Zoran Vujković

    Biomedicinska istraživanja, Vol 11, Iss 1, Pp 20-

    2020  Volume 28

    Abstract: Summary Introduction. The amniotic membrane is used in transplant surgery, ophthalmology and dermatology. Various methods have been developed to preserve amniotic membrane: hypothermic storage, cryopreservation, lyophilization. Transplantation of fresh ... ...

    Abstract Summary Introduction. The amniotic membrane is used in transplant surgery, ophthalmology and dermatology. Various methods have been developed to preserve amniotic membrane: hypothermic storage, cryopreservation, lyophilization. Transplantation of fresh amniotic membrane showed low inflammatory response. The efficient antibiotic solutions are carefully chosen for the hypothermic storage of amniotic membranes. The aim of this study was to compare the efficacy of two antibiotic solutions for the hypothermic amniotic membrane preservation and the structure of the amniotic membrane after the preservation process. Methods. Fifteen amniotic membranes were prepared and hypothermically stored in penicillin solution in BSS (2000 IU/ml) while the remaining fifteen in an antibiotic solution containing: benzylpenicillin (50 µg/ml), gentamicin (100 µg/ml), ciprofloxacin (200 µg/ml) and fluconazole (100 µg/ml). All amniotic membranes were microbiologically tested after preparation and after hypothermic storage for two weeks. Histological analysis of thirty amniotic membranes was performed after the process of preservation. Results. Fifteen amniotic membranes were sterile after hypothermic preservation in the penicillin solution. Also, fifteen amniotic membranes were sterile after hypothermic preservation in the solution of antibacterial agents (penicillin, gentamicin, ciprofloxacin) and antifungal agent fluconazole. The amniotic membrane had a normal structure and thickness of 35.33±11.03 μm. Conclusion. Both antibiotic solutions, one that contains only penicillin and one that contains multiple antibacterial agents and fluconazole, provide sterility of fresh hypothermically stored amniotic membranes for two weeks. In the preparation of fresh hypothermically stored amniotic membrane, a solution with multiple antibiotics is preferred. The normal tissue structure of the amniotic membrane was histologically confirmed after the process of preservation.
    Keywords amniotic membrane ; preservation ; tissue ; histological characteristics ; Medicine ; R
    Subject code 571
    Language Bosnian
    Publishing date 2020-06-01T00:00:00Z
    Publisher University of East Sarajevo
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: EUS-guided drainage of debris-containing pancreatic pseudocysts by using combined endoprosthesis and a nasocystic drain.

    Zerem, Enver / Pavlović-Čalić, Nada / Mavija, Zoran

    Gastrointestinal endoscopy

    2014  Volume 79, Issue 4, Page(s) 694–695

    MeSH term(s) Cyst Fluid ; Drainage/methods ; Endosonography/methods ; Female ; Humans ; Male ; Pancreatic Pseudocyst/surgery ; Stents ; Ultrasonography, Interventional/methods
    Language English
    Publishing date 2014-04
    Publishing country United States
    Document type Comment ; Letter
    ZDB-ID 391583-9
    ISSN 1097-6779 ; 0016-5107
    ISSN (online) 1097-6779
    ISSN 0016-5107
    DOI 10.1016/j.gie.2013.10.036
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  6. Article ; Online: COVID-19 infection in patients with malignant diseases

    Gojković Zdenka / Đokanović Dejan / Nikić Gordan / Jović-Đokanović Olja / Mavija Zoran / Rakita Ivanka / Jungić Saša / Vještica Milka / Berendika Jelena / Višekruna Tamara

    Vojnosanitetski Pregled, Vol 77, Iss 11, Pp 1235-

    2020  Volume 1236

    Abstract: ... ...

    Abstract nema
    Keywords nema ; Medicine (General) ; R5-920
    Language English
    Publishing date 2020-01-01T00:00:00Z
    Publisher Military Health Department, Ministry of Defance, Serbia
    Document type Article ; Online
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  7. Article ; Online: Prognostic value of acute fluid collections diagnosed by ultrasound in the early assessment of severity of acute pancreatitis.

    Zerem, Enver / Imamović, Goran / Latić, Ferid / Mavija, Zoran

    Journal of clinical ultrasound : JCU

    2013  Volume 41, Issue 4, Page(s) 203–209

    Abstract: Purpose: To evaluate the prognostic value of acute fluid collections (AFC) diagnosed by conventional transabdominal ultrasound in the early assessment of severity acute pancreatitis (AP).: Methods: We studied 128 consecutive patients with AP between ... ...

    Abstract Purpose: To evaluate the prognostic value of acute fluid collections (AFC) diagnosed by conventional transabdominal ultrasound in the early assessment of severity acute pancreatitis (AP).
    Methods: We studied 128 consecutive patients with AP between March 2006 and March 2011. The predictor was the number of AFC. Outcome measure was the occurrence of complications. Abdominal sonogram, contrast-enhanced CT, and pancreatitis-specific clinical and laboratory findings were performed.
    Results: AFC were associated with complications (p < 0.0001), Balthazar grade (p = 0.004), Ranson score (p < 0.0001), and the majority of clinical, radiologic, and biochemical parameters for predicting complications of AP (p < 0.05). Univariate logistic regression also revealed significant association between the number of AFC and the occurrence of complications (OR 4.4; 95% CI 2.5-7.6). After the adjustment for covariates, AFC remained prognostic for complications and a cutoff point of >1 AFC was prognostic of their occurrence with 88% sensitivity and 82% specificity.
    Conclusions: AFC are related to the clinical course of AP and can predict its severity
    MeSH term(s) Acute Disease ; Adult ; Ascites/diagnostic imaging ; Ascites/etiology ; Female ; Humans ; Logistic Models ; Male ; Middle Aged ; Multivariate Analysis ; Pancreatitis/complications ; Pancreatitis/diagnostic imaging ; Prognosis ; ROC Curve ; Severity of Illness Index ; Tomography, X-Ray Computed ; Ultrasonography
    Language English
    Publishing date 2013-05
    Publishing country United States
    Document type Clinical Trial ; Journal Article
    ZDB-ID 189393-2
    ISSN 1097-0096 ; 0091-2751
    ISSN (online) 1097-0096
    ISSN 0091-2751
    DOI 10.1002/jcu.21995
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    Zs.A 1186: Show issues Location:
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  8. Article ; Online: Is irrigation necessary during endoscopic necrosectomy of pancreatic necroses?

    Zerem, Enver / Imamović, Goran / Mavija, Zoran

    Surgical endoscopy

    2012  Volume 26, Issue 10, Page(s) 2995–6; author reply 2997

    MeSH term(s) Endoscopy, Digestive System/methods ; Endosonography/methods ; Female ; Humans ; Male ; Pancreas/pathology ; Pancreatitis/surgery
    Language English
    Publishing date 2012-04-26
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 639039-0
    ISSN 1432-2218 ; 0930-2794
    ISSN (online) 1432-2218
    ISSN 0930-2794
    DOI 10.1007/s00464-012-2257-9
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    Zs.A 2214: Show issues Location:
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  9. Article ; Online: Comments on the article about correlation between computerized tomography and surgery in acute pancreatitis.

    Zerem, Enver / Imamović, Goran / Mavija, Zoran / Haračić, Bahrija

    World journal of gastroenterology

    2011  Volume 17, Issue 3, Page(s) 407–408

    Abstract: We read with great interest the article by Vege et al published in issue 34 of World J Gastroenterol 2010. The article evaluates the ability of contrast-enhanced computerized tomography (CECT) to characterize the nature of peripancreatic collections ... ...

    Abstract We read with great interest the article by Vege et al published in issue 34 of World J Gastroenterol 2010. The article evaluates the ability of contrast-enhanced computerized tomography (CECT) to characterize the nature of peripancreatic collections found at surgery. The results of their study indicate that most of the peripancreatic collections seen on CECT in patients with severe acute pancreatitis who require operative intervention contain necrotic tissue and CECT has a limited role in differentiating various types of collections. However, there are some points that need to be addressed, including data about the stage of acute pancreatitis in which CECT was done and the time span between CECT examination and surgery.
    MeSH term(s) Acute Disease ; Humans ; Necrosis/pathology ; Pancreatitis/diagnostic imaging ; Pancreatitis/pathology ; Pancreatitis/surgery ; Tomography, X-Ray Computed/methods
    Language English
    Publishing date 2011-01-05
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2185929-2
    ISSN 2219-2840 ; 1007-9327
    ISSN (online) 2219-2840
    ISSN 1007-9327
    DOI 10.3748/wjg.v17.i3.407
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