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  1. Article: Herpesviridae and Atypical Bacteria Co-Detections in Lower Respiratory Tract Samples of SARS-CoV-2-Positive Patients Admitted to an Intensive Care Unit.

    Grubelnik, Gašper / Korva, Miša / Kogoj, Rok / Polanc, Tina / Mavrič, Matej / Jevšnik Virant, Monika / Uršič, Tina / Keše, Darja / Seme, Katja / Petrovec, Miroslav / Jereb, Matjaž / Avšič-Županc, Tatjana

    Microorganisms

    2024  Volume 12, Issue 4

    Abstract: Shortly after the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), cases of viral, bacterial, and fungal coinfections in hospitalized patients became evident. This retrospective study investigates the prevalence of multiple ... ...

    Abstract Shortly after the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), cases of viral, bacterial, and fungal coinfections in hospitalized patients became evident. This retrospective study investigates the prevalence of multiple pathogen co-detections in 1472 lower respiratory tract (LRT) samples from 229 SARS-CoV-2-positive patients treated in the largest intensive care unit (ICU) in Slovenia. In addition to SARS-CoV-2, (rt)RT-PCR tests were used to detect cytomegalovirus (CMV), Epstein-Barr virus (EBV), herpes simplex virus 1 (HSV-1), herpes simplex virus 2 (HSV-2), varicella zoster virus (VZV), and atypical bacteria:
    Language English
    Publishing date 2024-03-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms12040714
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Severe immune thrombocytopenia in a critically ill COVID-19 patient.

    Martincic, Ziga / Skopec, Barbara / Rener, Karla / Mavric, Matej / Vovko, Tomaz / Jereb, Matjaz / Lukic, Milica

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

    2020  Volume 99, Page(s) 269–271

    Abstract: The novel coronavirus SARS-CoV-2 can cause a severe and even fatal respiratory illness named COVID-19. Apart from respiratory failure, COVID-19 may be associated with various autoimmune complications. We present a case of a critically ill patient with ... ...

    Abstract The novel coronavirus SARS-CoV-2 can cause a severe and even fatal respiratory illness named COVID-19. Apart from respiratory failure, COVID-19 may be associated with various autoimmune complications. We present a case of a critically ill patient with COVID-19 who developed severe immune thrombocytopenia that was successfully treated with a concomitant use of corticosteroids and intravenous immunoglobulins.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/complications ; Critical Illness ; Humans ; Male ; Middle Aged ; Pandemics ; Platelet Transfusion ; Pneumonia, Viral/complications ; Purpura, Thrombocytopenic, Idiopathic/etiology ; Purpura, Thrombocytopenic, Idiopathic/therapy ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-08-06
    Publishing country Canada
    Document type Case Reports ; Journal Article
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2020.08.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Severe immune thrombocytopenia in a critically ill COVID-19 patient

    Martincic, Ziga / Skopec, Barbara / Rener, Karla / Mavric, Matej / Vovko, Tomaz / Jereb, Matjaz / Lukic, Milica

    Int J Infect Dis

    Abstract: The novel coronavirus SARS-CoV-2 can cause a severe and even fatal respiratory illness named COVID-19. Apart from respiratory failure, COVID-19 may be associated with various autoimmune complications. We present a case of a critically ill patient with ... ...

    Abstract The novel coronavirus SARS-CoV-2 can cause a severe and even fatal respiratory illness named COVID-19. Apart from respiratory failure, COVID-19 may be associated with various autoimmune complications. We present a case of a critically ill patient with COVID-19 who developed severe immune thrombocytopenia that was successfully treated with a concomitant use of corticosteroids and intravenous immunoglobulins.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #696202
    Database COVID19

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  4. Article ; Online: Severe immune thrombocytopenia in a critically ill COVID-19 patient

    Martincic, Ziga / Skopec, Barbara / Rener, Karla / Mavric, Matej / Vovko, Tomaz / Jereb, Matjaz / Lukic, Milica

    International Journal of Infectious Diseases

    2020  Volume 99, Page(s) 269–271

    Keywords Microbiology (medical) ; Infectious Diseases ; General Medicine ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2020.08.002
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Usefulness of presepsin as diagnostic and prognostic marker of sepsis in daily clinical practice.

    Jereb, Matjaz / Mavric, Matej / Skvarc, Miha / Drobnic, Alja / Dolenc, Spela / Strunjas, Natalija Planinc / Luksic, Boris / Kmet, Nina Grasselli

    Journal of infection in developing countries

    2019  Volume 13, Issue 11, Page(s) 1038–1044

    Abstract: Introduction: Sepsis represents a major cause of morbidity and mortality in critically ill patients. Early diagnosis and appropriate treatment have a crucial influence on survival. The aim of this study was to evaluate the diagnostic and prognostic role ...

    Abstract Introduction: Sepsis represents a major cause of morbidity and mortality in critically ill patients. Early diagnosis and appropriate treatment have a crucial influence on survival. The aim of this study was to evaluate the diagnostic and prognostic role of presepsin (sCD14) in patients with sepsis.
    Methodology: Fifty-four consecutive adult patients with sepsis and 26 patients with aseptic meningitis as a control group were included in this prospective observational study. In all patients included in the study, levels of C-reactive protein (CRP), presepsin, lactate, and a count of leukocytes and neutrophils were determined on admission. In those with suspected bacterial infection, two separate blood cultures were obtained and procalcitonin (PCT) concentration was detected. Plasma presepsin and PCT concentrations in septic group patients were followed on days 2, 3 and 7 after enrollment.
    Results: The median presepsin serum concentration in patients with sepsis was 1614 pg/mL and in the control group it was 203 pg/mL (p < 0.001). Presepsin levels in patients with septic shock were higher than in sepsis patients (p < 0.014). The mean presepsin concentrations were higher in deceased than in surviving patients (p = 0.009). The trend of changes in presepsin concentrations in deceased patients was significantly different than in the surviving patients (p = 0.018). There were no statistically significant differences in the concentration of presepsin or other biomarkers in patients with Gram negative or Gram positive bacteria.
    Conclusions: Presepsin may be used as a diagnostic marker of systemic bacterial infection and can predict the severity and outcome of sepsis.
    MeSH term(s) APACHE ; Area Under Curve ; Biomarkers/blood ; Case-Control Studies ; Female ; Humans ; Lactic Acid/blood ; Lipopolysaccharide Receptors/blood ; Male ; Peptide Fragments/blood ; Prognosis ; Sepsis/blood ; Sepsis/diagnosis ; Sepsis/mortality ; Sepsis/therapy
    Chemical Substances Biomarkers ; Lipopolysaccharide Receptors ; Peptide Fragments ; presepsin protein, human ; Lactic Acid (33X04XA5AT)
    Language English
    Publishing date 2019-11-30
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2394024-4
    ISSN 1972-2680 ; 2036-6590
    ISSN (online) 1972-2680
    ISSN 2036-6590
    DOI 10.3855/jidc.11764
    Database MEDical Literature Analysis and Retrieval System OnLINE

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