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  1. Article ; Online: Association Between Neighborhood Deprivation and Number of Rheumatology Providers.

    Mbonu, Ikechukwu / Tai, Shannon / Bartels, Christie M / Putman, Michael

    Arthritis care & research

    2022  Volume 75, Issue 1, Page(s) 9–13

    Abstract: Objective: Geographic disparities in the distribution and practice patterns of rheumatology providers may negatively impact patients with rheumatic diseases. The objective of this study was to describe the distribution of rheumatologists with respect to ...

    Abstract Objective: Geographic disparities in the distribution and practice patterns of rheumatology providers may negatively impact patients with rheumatic diseases. The objective of this study was to describe the distribution of rheumatologists with respect to the Area Deprivation Index (ADI) and to identify differences in practice patterns among Medicare Part D rheumatologist prescribers.
    Methods: We identified 5,882 rheumatologists who served a mean ± SD of 280 ± 208 Medicare Part D beneficiaries per year. In a Poisson regression model of the number of rheumatologists and the ADI of their practice location, for every increase of 10 on the ADI scale (range 0-100; higher = higher deprivation), there were 20.3% fewer rheumatologists (P < 0.001), resulting in 2.1 times as many rheumatologists per 100,000 people in the first ADI quintile when compared to the fifth ADI quintile.
    Results: The number of rheumatologists peaked in 2016 and decreased steadily thereafter across all quintiles. The prescribing rate per 100 beneficiaries was significantly different between quintiles across all studied drug classes except for opioids, but the trends were inconsistent and of unclear clinical significance.
    Conclusion: Rheumatologists tended to practice in areas with less deprivation, resulting in twice as many rheumatologists per 100,000 people in the quintile of lowest deprivation as opposed to the quintile with the highest deprivation. Public policy makers should be aware of these data and take steps to mitigate disparities in access to care as the rheumatology workforce shrinks.
    MeSH term(s) Aged ; Humans ; United States/epidemiology ; Rheumatology ; Medicare ; Rheumatologists ; Rheumatic Diseases ; Workforce
    Language English
    Publishing date 2022-11-18
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 645059-3
    ISSN 2151-4658 ; 0893-7524 ; 2151-464X
    ISSN (online) 2151-4658
    ISSN 0893-7524 ; 2151-464X
    DOI 10.1002/acr.25036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Cul de Sac : An Unusual Presentation of Giant Cell Arteritis.

    Osuorji, Chinenye / Ojumah, Naomi / Adedoyin, Oluwafeyi / Okoye, Okechukwu / Mbonu, Ikechukwu

    Cureus

    2021  Volume 13, Issue 7, Page(s) e16361

    Abstract: Giant cell arteritis (GCA), previously referred to as temporal arteritis, continues to pose significant diagnostic challenges to clinicians as it could have unusual and atypical presentations. We present the case of a 69-year-old Caucasian male who had ... ...

    Abstract Giant cell arteritis (GCA), previously referred to as temporal arteritis, continues to pose significant diagnostic challenges to clinicians as it could have unusual and atypical presentations. We present the case of a 69-year-old Caucasian male who had presented with painful scrotal swelling and bilateral arm pain and was eventually diagnosed with GCA based on histological findings. His symptoms resolved completely with the initiation of high-dose steroids. It is important to note that some clinical manifestations of GCA could be subtle, atypical, and maybe entirely extracranial. A high index of suspicion is helpful when diagnosing patients who present with non-specific or constitutional symptoms as delay in diagnosis or treatment in these patients could result in severe adverse outcomes.
    Language English
    Publishing date 2021-07-13
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.16361
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Authorship Trends in the Rheumatology Literature, 1990-2020.

    Mbonu, Ikechukwu V / Nemesh, Iryna / Suelzer, Elizabeth / Thorgerson, Abigail / Putman, Michael

    The Journal of rheumatology

    2021  Volume 48, Issue 9, Page(s) 1493–1494

    MeSH term(s) Authorship ; Humans ; Publishing ; Rheumatology
    Language English
    Publishing date 2021-05-01
    Publishing country Canada
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 194928-7
    ISSN 1499-2752 ; 0315-162X
    ISSN (online) 1499-2752
    ISSN 0315-162X
    DOI 10.3899/jrheum.210164
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Atypical Presentation of Small Lymphocytic Lymphoma with Pericardial Effusion.

    Nnaoma, Christopher / Chika-Nwosuh, Ogechukwu / Mbonu, Ikechukwu / Sossou, Christoph W / Okonkwo, Christian C / Isedeh, Anthony

    The American journal of case reports

    2019  Volume 20, Page(s) 1128–1131

    Abstract: BACKGROUND Small lymphocytic lymphoma (SLL) is a low-grade B-cell non-Hodgkin lymphoma and is the solid tumor equivalent of chronic lymphocytic leukemia (CLL) that is found in the peripheral blood. SLL typically presents with lymphadenopathy and is ... ...

    Abstract BACKGROUND Small lymphocytic lymphoma (SLL) is a low-grade B-cell non-Hodgkin lymphoma and is the solid tumor equivalent of chronic lymphocytic leukemia (CLL) that is found in the peripheral blood. SLL typically presents with lymphadenopathy and is rarely associated with cardiac involvement. This report is of a case of lymphomatous pericardial effusion in a 61-year-old woman who presented with dyspnea. CASE REPORT A 61-year-old woman presented to the emergency department with a three-month history of worsening shortness of breath on exertion. Her symptoms progressed to shortness of breath at rest, with night sweats and chills. She had no weight loss. She was found to have a pericardial effusion, and an urgent pericardiocentesis was performed to prevent cardiac tamponade. Analysis of the pericardial fluid was consistent with a diagnosis of SLL. A bone marrow biopsy and a biopsy of a renal mass were consistent with a diagnosis of SLL. She was treated with rituximab and bendamustine with granulocyte-colony stimulating factor (G-CSF) support and was discharged home. CONCLUSIONS A case is presented of a rare association between SLL and pericardial effusion with a favorable outcome following urgent pericardiocentesis to prevent cardiac tamponade followed by chemotherapy.
    MeSH term(s) Computed Tomography Angiography ; Dyspnea/etiology ; Female ; Humans ; Leukemia, Lymphocytic, Chronic, B-Cell/diagnosis ; Middle Aged ; Pericardial Effusion/diagnostic imaging ; Pericardial Effusion/etiology ; Tomography, X-Ray Computed
    Language English
    Publishing date 2019-07-31
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2517183-5
    ISSN 1941-5923 ; 1941-5923
    ISSN (online) 1941-5923
    ISSN 1941-5923
    DOI 10.12659/AJCR.915576
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A Case of Systemic Lupus Erythematosus Presenting as Autoimmune Myelofibrosis.

    Mbonu, Ikechukwu / Sossou, Christoph / Nnaoma, Christopher B / Sun, Xinlai / Schleicher, Lori / Xiong, Wen

    The American journal of case reports

    2019  Volume 20, Page(s) 937–940

    Abstract: BACKGROUND Systemic lupus erythematosus (SLE) is characterized by multiorgan involvement and presence of autoantibodies. SLE has a broad range of presentations and manifestations, and as such, its course and organ involvement are unpredictable. The ... ...

    Abstract BACKGROUND Systemic lupus erythematosus (SLE) is characterized by multiorgan involvement and presence of autoantibodies. SLE has a broad range of presentations and manifestations, and as such, its course and organ involvement are unpredictable. The disease results from the interaction of genes, environment, and random effects combining to lead to a loss of tolerance to self-antigens and active autoimmunity. Autoimmune myelofibrosis is a type of non-malignant bone marrow fibrosis that occurs in the presence of systemic autoimmune disease. Cytopenias such as anemia, leukopenia, and thrombocyotopenia are common manifestations of SLE; however, myelofibrosis is a less common and far less recognized complication of SLE. CASE REPORT We report a case of a young African American female who presented with severe anemia and leukopenia, subsequently diagnosed with myelofibrosis and then eventually SLE. The identification of myelofibrosis in SLE is critical as it can be a devastating condition when untreated. Fortunately, autoimmune myelofibrosis in SLE is reversible with treatment of the underlying condition. CONCLUSIONS Autoimmune myelofibrosis is a rare complication of SLE. Autoimmune myelofibrosis could be the first and only presenting feature of SLE. It is sensible to recognize this relationship, as prompt diagnosis and treatment is crucial. Corticosteroids have been shown to be useful in treating both SLE and the associated autoimmune myelofibrosis.
    MeSH term(s) Anemia/etiology ; Autoimmunity ; Diagnosis, Differential ; Female ; Humans ; Leukopenia/etiology ; Lupus Erythematosus, Systemic/complications ; Lupus Erythematosus, Systemic/diagnosis ; Primary Myelofibrosis/etiology ; Thrombocytopenia/etiology ; Young Adult
    Language English
    Publishing date 2019-07-01
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2517183-5
    ISSN 1941-5923 ; 1941-5923
    ISSN (online) 1941-5923
    ISSN 1941-5923
    DOI 10.12659/AJCR.916001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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