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  1. Article ; Online: Acute aortic occlusion presenting as paraplegia: a catastrophic complication in an elective surgical patient.

    Mcclain, Robert L / Pai, Sher-Lu

    A & A case reports

    2013  Volume 1, Issue 4, Page(s) 64–66

    Abstract: Acute aortic occlusion by massive thoracoabdominal thrombi has been reported as a serious complication in patients undergoing major vascular or cardiac surgical procedures. However, this complication occurs rarely after ambulatory procedures. In this ... ...

    Abstract Acute aortic occlusion by massive thoracoabdominal thrombi has been reported as a serious complication in patients undergoing major vascular or cardiac surgical procedures. However, this complication occurs rarely after ambulatory procedures. In this case report, we describe a patient who experienced paraplegia after an elective laparoscopic cholecystectomy in whom acute aortic thromboembolic occlusion was subsequently diagnosed. We emphasize the importance of accurate neurologic and cardiovascular history taking and examination throughout the perioperative period along with the appropriate diagnostic studies to expeditiously arrive at a diagnosis of such a rare complication.
    Language English
    Publishing date 2013-11-15
    Publishing country United States
    Document type Journal Article
    ISSN 2325-7237
    ISSN (online) 2325-7237
    DOI 10.1097/ACC.0b013e3182973a4f
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Anesthetic pharmacology and perioperative considerations for the end stage liver disease patient.

    Mcclain, Robert L / Ramakrishna, Harish / Aniskevich, Stephen / Cartwright, Joseph A / Phar, Leah G Ward / Pai, Sher-Lu / Rodrigues, Eduardo S / Martin, Archer K / Shine, Timothy S

    Current clinical pharmacology

    2014  Volume 10, Issue 1, Page(s) 35–46

    Abstract: The number of patients with end stage liver disease is growing worldwide. This is likely a result of advances in medical science that have allowed these patients to lead longer lives since the incidence of diseases such as alcoholic cirrhosis and viral ... ...

    Abstract The number of patients with end stage liver disease is growing worldwide. This is likely a result of advances in medical science that have allowed these patients to lead longer lives since the incidence of diseases such as alcoholic cirrhosis and viral hepatitis have remained stable or even decreased in recent years, at least in more developed nations. Many of these patients will require anesthetic care at some point. The understanding and application of basic principles of pharmacokinetics is paramount to the practice of anesthesia. An understanding of pharmacokinetic principles provides the anesthesiologist with a scientific foundation for achieving therapeutic objectives associated with the use of any drug; however, pathologic conditions often alter the expected kinetic profile of many drugs. Anesthesia providers caring for these patients must be aware of the altered pharmacokinetics that may occur in these patients. We review normal liver physiology, pathophysiology of liver disease in general, and how liver failure affects the pharmacokinetics and pharmacodynamics of anesthetic agents; providing some specific examples.
    MeSH term(s) Anesthesiology/methods ; Anesthetics/administration & dosage ; Anesthetics/pharmacokinetics ; Animals ; End Stage Liver Disease/epidemiology ; End Stage Liver Disease/physiopathology ; End Stage Liver Disease/surgery ; Humans ; Liver Transplantation/methods
    Chemical Substances Anesthetics
    Language English
    Publishing date 2014-01-27
    Publishing country United Arab Emirates
    Document type Journal Article ; Review
    ZDB-ID 2250809-0
    ISSN 2212-3938 ; 1574-8847
    ISSN (online) 2212-3938
    ISSN 1574-8847
    DOI 10.2174/1574884709666140212110036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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