Artikel: Multiomics atlas-assisted discovery of transcription factors enables specific cell state programming.
bioRxiv : the preprint server for biology
2023
Abstract: The same types of cells can assume diverse states with varying functionalities. Effective cell therapy can be achieved by specifically driving a desirable cell state, which requires the elucidation of key transcription factors (TFs). Here, we integrated ... ...
| Abstract | The same types of cells can assume diverse states with varying functionalities. Effective cell therapy can be achieved by specifically driving a desirable cell state, which requires the elucidation of key transcription factors (TFs). Here, we integrated epigenomic and transcriptomic data at the systems level to identify TFs that define different CD8 One sentence summary: Multiomics atlas enables the systematic identification of cell-state specifying transcription factors for therapeutic cell state programming. |
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| Sprache | Englisch |
| Erscheinungsdatum | 2023-12-05 |
| Erscheinungsland | United States |
| Dokumenttyp | Preprint |
| DOI | 10.1101/2023.01.03.522354 |
| Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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