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  1. Article ; Conference proceedings: Complicated Barrett’s Lesions and Subsequent Endoscopic Eradication Therapy: A Single Centre Irish Experience

    Lloyd, A. / Moran, C. / Mcdonald, C. / Murphy, T.

    Endoscopy

    2024  Volume 56, Issue S 02

    Event/congress ESGE Days 2024, Berlin, Germany, 2024-04-25
    Language English
    Publishing date 2024-04-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/s-0044-1783622
    Database Thieme publisher's database

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  2. Article ; Online: Current concepts in the management of radial head fractures: a national survey and review of the literature.

    Barakat, A / Mcdonald, C / Singh, H

    Annals of the Royal College of Surgeons of England

    2022  Volume 105, Issue 5, Page(s) 469–475

    Abstract: Introduction: This study aims to report on current practice in the management of radial head fractures (RHFs) in the United Kingdom and to review the literature to identify areas for future investigation.: Methods: A 12-question online survey was ... ...

    Abstract Introduction: This study aims to report on current practice in the management of radial head fractures (RHFs) in the United Kingdom and to review the literature to identify areas for future investigation.
    Methods: A 12-question online survey was sent to 500 surgeon members of the British Elbow and Shoulder Society in 2021. Questions focused on clinical assessment, indications for surgical treatment and willingness to participate in future studies. Descriptive statistical analysis summarised the responses.
    Results: The response rate was 20.4% (
    Discussion: There is considerable variability in the management of RHF among an experienced cohort of surgeons. With the interest declared by the participating surgeons, there is a call for a well-designed sufficiently powered RCT.
    MeSH term(s) Humans ; Radial Head and Neck Fractures ; Radius Fractures/surgery ; Fracture Fixation ; Arthroplasty ; Elbow Joint/surgery ; Treatment Outcome ; Fracture Fixation, Internal ; Randomized Controlled Trials as Topic
    Language English
    Publishing date 2022-10-14
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 80044-2
    ISSN 1478-7083 ; 0035-8843
    ISSN (online) 1478-7083
    ISSN 0035-8843
    DOI 10.1308/rcsann.2022.0109
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Early oral cancer management during the COVID-19 period.

    Lyons, A / Mcdonald, C / Kanatas, A / Rogers, S N

    The British journal of oral & maxillofacial surgery

    2020  Volume 58, Issue 8, Page(s) 885–887

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Humans ; Mouth Neoplasms/surgery ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-08-13
    Publishing country Scotland
    Document type Editorial
    ZDB-ID 605685-4
    ISSN 1532-1940 ; 0266-4356
    ISSN (online) 1532-1940
    ISSN 0266-4356
    DOI 10.1016/j.bjoms.2020.06.043
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  4. Article: Stakeholder views on the design of National Health Service perinatal mental health services: 360-degree survey.

    Scott, John / Mcdonald, Christopher / McRobbie, Sarah / Watt, Blair / Young, Judith / Morris, Jane

    BJPsych bulletin

    2023  Volume 48, Issue 1, Page(s) 18–24

    Abstract: Aims and method: At the start of a new community perinatal mental health service in Scotland we sought the opinions and aspirations of professional and lay stakeholders. A student elective project supported the creation of an anonymous 360-degree online ...

    Abstract Aims and method: At the start of a new community perinatal mental health service in Scotland we sought the opinions and aspirations of professional and lay stakeholders. A student elective project supported the creation of an anonymous 360-degree online survey of a variety of staff and people with lived experience of suffering from or managing perinatal mental health problems. The survey was designed and piloted with trainees and volunteer patients.
    Results: A rich variety of opinions was gathered from the 60 responses, which came from a reasonably representative sample. Respondents provided specific answers to key questions and wrote free-text recommendations and concerns to inform service development.
    Clinical implications: There is clear demand for the new expanded service, with strong support for provision of a mother and baby unit in the North of Scotland. The digital survey method could be adapted to generate future surveys to review satisfaction with service development and generate ideas for further change.
    Language English
    Publishing date 2023-05-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2816886-0
    ISSN 2056-4708 ; 2056-4694
    ISSN (online) 2056-4708
    ISSN 2056-4694
    DOI 10.1192/bjb.2023.26
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Early oral cancer management during the COVID-19 period

    Lyons, A. / Mcdonald, C. / Kanatas, A. / Rogers, S.N.

    British Journal of Oral and Maxillofacial Surgery

    2020  Volume 58, Issue 8, Page(s) 885–887

    Keywords Surgery ; Oral Surgery ; Otorhinolaryngology ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 605685-4
    ISSN 1532-1940 ; 0266-4356
    ISSN (online) 1532-1940
    ISSN 0266-4356
    DOI 10.1016/j.bjoms.2020.06.043
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article: Management of Displaced Intra-Articular Calcaneal Fractures: A Comparative Study of Open and Minimally Invasive Surgery.

    Islam, Amirul / Mcdonald, Charles / Aljawadi, Ahmed / Niazi, Noman / Pillai, Anand

    Cureus

    2020  Volume 12, Issue 8, Page(s) e9547

    Abstract: Objectives The ideal treatment of displaced intra-articular calcaneal fractures continues to be a subject of debate. The aim of the study was to compare the radiological outcome, cumulative radiation exposure, surgical time, time to surgery, wound ... ...

    Abstract Objectives The ideal treatment of displaced intra-articular calcaneal fractures continues to be a subject of debate. The aim of the study was to compare the radiological outcome, cumulative radiation exposure, surgical time, time to surgery, wound healing times and cost involved in minimally invasive surgery (MIS) and open reduction internal fixation (ORIF) for calcaneal fractures. Methods This was a retrospective study of 39 calcaneum operated in our unit during 2012 to 2019, of which 20 had undergone ORIF and 19 had been operated upon following MIS. Results A total of 39 calcanea (37 patients) were operated, of which 20 had open procedure and 19 had MIS procedure, including one bilateral surgery in each group. Mean age of the patients in the MIS group was 42.18 years (range: 15-68 years) and that of the patients in the open group was 43 years (range: 21-75 years). Of the fractures, 53.84% (n = 21) was Sanders type III, 28.20% (n = 11) was type II and 17.94% (n = 7) was type IV. There was no statistically significant difference in the mean correction of Bohler's angle and Gissane's angle between the groups. The mean cost for implant used for each open procedure was £882.79, and the implant cost for each MIS procedure was £142.89. Mean utilisation of cumulative X-ray dose was significantly higher in MIS (0.764 mGy) in comparison to open surgery (0.392 mGy). The average surgical time for MIS was 64.9 minutes and that of open surgery was 106.3 minutes. Average waiting time for MIS was 6.6 days and that for ORIF was 9.8 days. Wound healing was quicker (average 13.4 days) in MIS than ORIF (average 17.2 days). All these differences were statistically significant. Conclusions Minimally invasive calcaneal fracture surgery is quicker and cheaper and can be performed earlier. It is associated with early wound healing, although it requires higher cumulative radiation dose.
    Language English
    Publishing date 2020-08-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.9547
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Underrepresentation of Minorities and Underreporting of Race and Ethnicity in Crohn's Disease Clinical Trials.

    Sedano, Rocio / Hogan, Malcolm / Mcdonald, Cassandra / Aswani-Omprakash, Tina / Ma, Christopher / Jairath, Vipul

    Gastroenterology

    2021  Volume 162, Issue 1, Page(s) 338–340.e2

    MeSH term(s) Adult ; Clinical Trials as Topic ; Crohn Disease/diagnosis ; Crohn Disease/ethnology ; Crohn Disease/therapy ; Ethnic and Racial Minorities ; Female ; Health Status Disparities ; Healthcare Disparities/ethnology ; Humans ; Male ; Minority Health/ethnology ; Patient Selection ; Race Factors ; Research Subjects
    Language English
    Publishing date 2021-09-27
    Publishing country United States
    Document type Letter ; Systematic Review
    ZDB-ID 80112-4
    ISSN 1528-0012 ; 0016-5085
    ISSN (online) 1528-0012
    ISSN 0016-5085
    DOI 10.1053/j.gastro.2021.09.054
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 572: Show issues

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  9. Article ; Online: Genetic and inflammatory effects on childhood trauma and cognitive functioning in patients with schizophrenia and healthy participants.

    Corley, Emma / Patlola, Saahithh Redddi / Laighneach, Aodán / Corvin, Aiden / McManus, Ross / Kenyon, Marcus / Kelly, John P / Mckernan, Declan P / King, Sinead / Hallahan, Brian / Mcdonald, Colm / Morris, Derek W / Donohoe, Gary

    Brain, behavior, and immunity

    2023  Volume 115, Page(s) 26–37

    Abstract: Recent studies have reported a negative association between exposure to childhood trauma, including physical neglect, and cognitive functioning in patients with schizophrenia. Childhood trauma has been found to influence immune functioning, which may ... ...

    Abstract Recent studies have reported a negative association between exposure to childhood trauma, including physical neglect, and cognitive functioning in patients with schizophrenia. Childhood trauma has been found to influence immune functioning, which may contribute to the risk of schizophrenia and cognitive symptoms of the disorder. In this study, we aimed to test the hypothesis that physical neglect is associated with cognitive ability, and that this association is mediated by a combined latent measure of inflammatory response, and moderated by higher genetic risk for schizophrenia. The study included 279 Irish participants, comprising 102 patients and 177 healthy participants. Structural equation modelling was used to perform mediation and moderation analyses. Inflammatory response was measured via basal plasma levels of IL-6, TNF-α, and CRP, and cognitive performance was assessed across three domains: full-scale IQ, logical memory, and the emotion recognition task. Genetic variation for schizophrenia was estimated using a genome-wide polygenic score based on genome-wide association study summary statistics. The results showed that inflammatory response mediated the association between physical neglect and all measures of cognitive functioning, and explained considerably more variance than any of the inflammatory markers alone. Furthermore, genetic risk for schizophrenia was observed to moderate the direct pathway between physical neglect and measures of non-social cognitive functioning in both patient and healthy participants. However, genetic risk did not moderate the mediated pathway associated with inflammatory response. Therefore, we conclude that the mediating role of inflammatory response and the moderating role of higher genetic risk may independently influence the association between adverse early life experiences and cognitive function in patients and healthy participants.
    MeSH term(s) Humans ; Schizophrenia ; Genome-Wide Association Study ; Adverse Childhood Experiences ; Healthy Volunteers ; Cognition/physiology
    Language English
    Publishing date 2023-09-23
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639219-2
    ISSN 1090-2139 ; 0889-1591
    ISSN (online) 1090-2139
    ISSN 0889-1591
    DOI 10.1016/j.bbi.2023.09.013
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    Zs.MO 327: Show issues

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  10. Article ; Online: Schizophrenia moderates the relationship between white matter integrity and cognition.

    Castro-de-Araujo, Luis F S / Allin, Mathew / Picchioni, Marco M / Mcdonald, Colm / Pantelis, Christos / Kanaan, Richard A A

    Schizophrenia research

    2018  Volume 199, Page(s) 250–256

    Abstract: Cognitive impairment is a primary feature of schizophrenia, with alterations in several cognitive domains appearing in the pre-morbid phase of the disorder. White matter microstructure is also affected in schizophrenia and considered to be related to ... ...

    Abstract Cognitive impairment is a primary feature of schizophrenia, with alterations in several cognitive domains appearing in the pre-morbid phase of the disorder. White matter microstructure is also affected in schizophrenia and considered to be related to cognition, but the relationship of the two is unclear. As interaction between cognition and white matter structure involves the interplay of several brain structures and cognitive abilities, investigative methods which can examine the interaction of multiple variables are preferred. A multiple-groups structural equation model (SEM) was used to assess the relationship between diffusion tension imaging data (fractional anisotropy of selected white matter tracts) and cognitive abilities of 196 subjects - 135 healthy subjects and 61 patients with schizophrenia. It was found that multiple-indicators, multiple-causes model best fitted the data analysed. Schizophrenia moderated the relation of white matter function on cognition with a large effect size. This paper extends previous work on modelling intelligence within a SEM framework by incorporating neurological elements into the model, and shows that white matter microstructure in patients with schizophrenia interacts with cognitive abilities.
    MeSH term(s) Adult ; Brain/diagnostic imaging ; Cognition ; Cognition Disorders/diagnostic imaging ; Cognition Disorders/etiology ; Diffusion Tensor Imaging ; Female ; Humans ; Male ; Schizophrenia/diagnostic imaging ; Schizophrenic Psychology ; White Matter/diagnostic imaging
    Language English
    Publishing date 2018-03-28
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639422-x
    ISSN 1573-2509 ; 0920-9964
    ISSN (online) 1573-2509
    ISSN 0920-9964
    DOI 10.1016/j.schres.2018.03.033
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 543: Show issues

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