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  1. Article ; Online: Mo

    Crozier, Anthony / Cocks, Matthew / Hesketh, Katie / Miller, Gemma / Mcgregor, Gordon / Thomas, Laura / Jones, Helen

    BMJ open

    2024  Volume 14, Issue 2, Page(s) e076734

    Abstract: Introduction: Cardiac rehabilitation (CR) can reduce cardiovascular mortality and improve health-related quality of life. In the United Kingdom, patient uptake of CR remains low (52%), falling well short of the target in the 2019 National Health Service ...

    Abstract Introduction: Cardiac rehabilitation (CR) can reduce cardiovascular mortality and improve health-related quality of life. In the United Kingdom, patient uptake of CR remains low (52%), falling well short of the target in the 2019 National Health Service long-term plan (85%). Mobile health (mHealth) technologies, offering biometric data to patients and healthcare professionals, may bridge the gap between supervised exercise and physical activity advice, enabling patients to engage in regular long-term physically active lifestyles. This randomised controlled trial (RCT) will evaluate the feasibility of mHealth technology when incorporated into a structured home-based walking intervention, in people with recent myocardial infarction.
    Methods and analysis: This is a feasibility, assessor blinded, parallel group RCT. Participants will be allocated to either CR standard care (control group) or CR standard care+mHealth supported exercise counselling (mHealth intervention group). Feasibility outcomes will include the number of patients approached, screened and eligible; the percentage of patients who decline CR (including reasons for declining), agree to CR and consent to being part of the study; the percentage of patients who enrol in standard CR and reasons for drop out; and the percentage of participants who complete clinical, physical and psychosocial outcomes to identify a suitable primary outcome for a future definitive trial.
    Ethics and dissemination: The trial was approved in the UK by the Northwest-Greater Manchester East Research Ethics Committee (22/NW/0301) and is being conducted in accordance with the Declaration of Helsinki and Good Clinical Practice. Results will be published in peer-reviewed journals and presented at national and international scientific meetings.
    Trial registration numbers: NCT05774587.
    MeSH term(s) Humans ; Cardiac Rehabilitation/methods ; Feasibility Studies ; Exercise ; Quality of Life ; Telemedicine ; Biometry ; Randomized Controlled Trials as Topic
    Language English
    Publishing date 2024-02-12
    Publishing country England
    Document type Clinical Trial Protocol ; Journal Article
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2023-076734
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: A Risk-Based Ecohydrological Approach to Assessing Environmental Flow Regimes

    Mcgregor, GlennB / Jonathan C. Marshall / Jaye S. Lobegeiger / Dean Holloway / Norbert Menke / Julie Coysh

    Environmental management. 2018 Mar., v. 61, no. 3

    2018  

    Abstract: For several decades there has been recognition that water resource development alters river flow regimes and impacts ecosystem values. Determining strategies to protect or restore flow regimes to achieve ecological outcomes is a focus of water policy and ...

    Abstract For several decades there has been recognition that water resource development alters river flow regimes and impacts ecosystem values. Determining strategies to protect or restore flow regimes to achieve ecological outcomes is a focus of water policy and legislation in many parts of the world. However, consideration of existing environmental flow assessment approaches for application in Queensland identified deficiencies precluding their adoption. Firstly, in managing flows and using ecosystem condition as an indicator of effectiveness, many approaches ignore the fact that river ecosystems are subjected to threatening processes other than flow regime alteration. Secondly, many focus on providing flows for responses without considering how often they are necessary to sustain ecological values in the long-term. Finally, few consider requirements at spatial-scales relevant to the desired outcomes, with frequent focus on individual places rather than the regions supporting sustainability. Consequently, we developed a risk-based ecohydrological approach that identifies ecosystem values linked to desired ecological outcomes, is sensitive to flow alteration and uses indicators of broader ecosystem requirements. Monitoring and research is undertaken to quantify flow-dependencies and ecological modelling is used to quantify flow-related ecological responses over an historical flow period. The relative risk from different flow management scenarios can be evaluated at relevant spatial-scales. This overcomes the deficiencies identified above and provides a robust and useful foundation upon which to build the information needed to support water planning decisions. Application of the risk assessment approach is illustrated here by two case studies.
    Keywords case studies ; ecological value ; ecosystems ; laws and regulations ; models ; monitoring ; planning ; relative risk ; resource management ; risk assessment process ; rivers ; water policy ; Queensland
    Language English
    Dates of publication 2018-03
    Size p. 358-374.
    Publishing place Springer US
    Document type Article
    ZDB-ID 1478932-2
    ISSN 1432-1009 ; 0364-152X
    ISSN (online) 1432-1009
    ISSN 0364-152X
    DOI 10.1007/s00267-017-0850-3
    Database NAL-Catalogue (AGRICOLA)

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  3. Book: CELL VOLUME TO AID ANALYSIS AND TECHNIQUE OF SOMATIC CELL COUNTS IN MILK

    SHELDRAKE, R.F. / HOARE, R.J.T. / WOODHOUSE, V.E. / MCGREGOR, G.D.

    1977  

    Institution NEW SOUTH WALES DEPT. OF AGRICULTURE, GLENFIELD (AUSTRALIA). VETERINARY RESEARCH STATION
    Keywords Milchdruese ; Physik ; Gehalt ; Physiologie ; Beurteilung ; Milch ; Teilstueck ; Mastitis ; Bearbeitung ; Herde ; Elektro ; Volumen ; Zelle ; Medizin ; Rind ; Methodik ; Nahrungsmittel
    Document type Book
    Database ELFIS - Nutrition, agriculture and forestry information system

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  4. Article: An examination of the precipitation delivery mechanisms for Dolleman Island, eastern Antarctic Peninsula

    Russell, A / Mcgregor, GR / Marshall, GJ

    Abstract: The variability of size and source of significant precipitation events were studied at an Antarctic ice core drilling site: Dolleman Island (DI), located on the eastern coast of the Antarctic Peninsula. Significant precipitation events that occur at DI ... ...

    Abstract The variability of size and source of significant precipitation events were studied at an Antarctic ice core drilling site: Dolleman Island (DI), located on the eastern coast of the Antarctic Peninsula. Significant precipitation events that occur at DI were temporally located in the European Centre for Medium-Range Weather Forecasting (ECMWF) reanalysis data set, ERA-40. The annual and summer precipitation totals from ERA-40 at DI both show significant increases over the reanalysis period. Three-dimensional backwards air parcel trajectories were then run for 5 d using the ECMWF ERA-15 wind fields. Cluster analyses were performed on two sets of these backwards trajectories: all days in the range 1979–1992 (the climatological time-scale) and a subset of days when a significant precipitation event occurred. The principal air mass sources and delivery mechanisms were found to be the Weddell Sea via lee cyclogenesis, the South Atlantic when there was a weak circumpolar trough (CPT) and the South Pacific when the CPT was deep. The occurrence of precipitation bearing air masses arriving via a strong CPT was found to have a significant correlation with the southern annular mode (SAM); however, the arrival of air masses from the same region over the climatological time-scale showed no such correlation. Despite the dominance in both groups of back trajectories of the westerly circulation around Antarctica, some other key patterns were identified. Most notably there was a higher frequency of lee cyclogenesis events in the significant precipitation trajectories compared to the climatological time-scale. There was also a tendency for precipitation trajectories to come from more northerly latitudes, mostly from 50–70°S. The El Niño Southern Oscillation (ENSO) was found to have a strong influence on the mechanism by which the precipitation was delivered; the frequency of occurrence of precipitation from the east (west) of DI increased during El Niño (La Niña) events.
    Language English
    Document type Article
    Database AGRIS - International Information System for the Agricultural Sciences and Technology

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