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  1. Article ; Online: The Critical Role of Hospitalists for Successful Hospital-SNF Integration Hospitalists and Hospital/SNF Integration.

    Mchugh, John / Shay, Patrick / Flansbaum, Bradley

    Journal of hospital medicine

    2019  Volume 14, Issue 3, Page(s) 192–193

    MeSH term(s) Hospitalists ; Hospitals ; Humans ; Patient Transfer ; Skilled Nursing Facilities
    Language English
    Publishing date 2019-02-27
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2233783-0
    ISSN 1553-5606 ; 1553-5592
    ISSN (online) 1553-5606
    ISSN 1553-5592
    DOI 10.12788/jhm.3161
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6276: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 542: Show issues

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  2. Article ; Online: Assessing neuromuscular junction stability from stimulated EMG in children.

    Pitt, Matthew C / Mchugh, John C / Deeb, Jacquie / Smith, Ralph A

    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology

    2017  Volume 128, Issue 2, Page(s) 290–296

    Abstract: Objective: We present our 9-year experience of stimulated EMG potential analysis using concentric electrodes (SPACE) to evaluate neuromuscular junction (NMJ) disorders in awake children. The technique uses high frequency filtration of stimulated motor ... ...

    Abstract Objective: We present our 9-year experience of stimulated EMG potential analysis using concentric electrodes (SPACE) to evaluate neuromuscular junction (NMJ) disorders in awake children. The technique uses high frequency filtration of stimulated motor unit potentials and applies peak detection software to estimate mean consecutive difference (MCD).
    Methods: SPACE was carried out in orbicularis oculi of 878 children (377 girls; median age 47months) between 2007 and 2015, stimulating the facial nerve with a monopolar cathode. Mean MCD-index (MCD-I) was expressed as a ratio of the measured MCD to the upper normal limit. Diagnostic accuracy was calculated for primary NMJ disorders based on the 660 cases with clinical follow-up data.
    Results: Primary NMJ disorders were present in 106 children, including 46 with genetically confirmed congenital myasthenic syndrome (CMS). Mean MCD-I was two times higher in children with primary NMJ disorders compared to others (205±108μs vs 94±38μs, p<0.005). After excluding children with neuronopathies, an MCD-I >100% had 84% sensitivity and 74% specificity for the primary NMJ disorders. Receiver operating characteristics (ROC) curve identified an MCD-I >115% as providing best diagnostic accuracy with sensitivity of 77% and specificity of 84%.
    Conclusion: SPACE is practicable and safe in unsedated children.
    Significance: In combination with routine EMG, it has high diagnostic accuracy and can facilitate recognition of paediatric NMJ transmission disorders.
    MeSH term(s) Child ; Child, Preschool ; Electrodes ; Electromyography/instrumentation ; Electromyography/methods ; Evoked Potentials, Motor ; Facial Nerve/physiopathology ; Female ; Humans ; Male ; Neuromuscular Diseases/diagnosis ; Neuromuscular Diseases/physiopathology ; Neuromuscular Junction/physiopathology ; Sensitivity and Specificity
    Language English
    Publishing date 2017-02
    Publishing country Netherlands
    Document type Evaluation Studies ; Journal Article
    ZDB-ID 1463630-x
    ISSN 1872-8952 ; 0921-884X ; 1388-2457
    ISSN (online) 1872-8952
    ISSN 0921-884X ; 1388-2457
    DOI 10.1016/j.clinph.2016.11.020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ui II Zs.140: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Correction and transformation of normative neurophysiological data: is there added value in the diagnosis of distal symmetrical peripheral neuropathy?

    Mchugh, John C / Connolly, Sean

    Muscle & nerve

    2011  Volume 44, Issue 6, Page(s) 890–896

    Abstract: Introduction: Despite theoretical advantages, the practical impact of mathematical correction of normative electrodiagnostic data is poorly quantified.: Methods: One hundred five healthy volunteers had clinical and neurophysiological assessment. The ... ...

    Abstract Introduction: Despite theoretical advantages, the practical impact of mathematical correction of normative electrodiagnostic data is poorly quantified.
    Methods: One hundred five healthy volunteers had clinical and neurophysiological assessment. The effects of age, height, gender, weight, and body mass index were explored using stepwise regression modeling. Reference values were derived from raw and adjusted data, which were transformed to allow appropriate use of parametric statistics. The diagnostic accuracy of derived limits was tested in patients at risk of distal symmetric peripheral neuropathy (DSPN) from chemotherapy.
    Results: The variability of our normative data was reduced by up to 69% through the use of regression modeling, but the overall benefits of mathematical correction were marginal. The most accurate reference limits were established using the 2.5th and 97.5th percentiles of the raw data.
    Conclusions: Stepwise statistical regression and mathematical transformation improve the distribution of normative data, but their practical impact for diagnosis of distal symmetrical polyneuropathy is small.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Data Interpretation, Statistical ; Databases, Factual/statistics & numerical data ; Female ; Humans ; Male ; Middle Aged ; Neural Conduction/physiology ; Peripheral Nervous System Diseases/diagnosis ; Peripheral Nervous System Diseases/physiopathology ; Sensory Thresholds/physiology ; Young Adult
    Language English
    Publishing date 2011-12
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 438353-9
    ISSN 1097-4598 ; 0148-639X
    ISSN (online) 1097-4598
    ISSN 0148-639X
    DOI 10.1002/mus.22190
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1449: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 551: Show issues

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