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  1. Article: Universal varicella vaccination. Comment.

    Macartney, Kristine / Mcintyre, Peter

    The Medical journal of Australia

    2005  Volume 183, Issue 5, Page(s) 278–279

    MeSH term(s) Adolescent ; Australia ; Chickenpox/prevention & control ; Chickenpox Vaccine/therapeutic use ; Child ; Herpes Zoster/prevention & control ; Humans ; Immunization Programs/trends ; Infant ; Outcome Assessment (Health Care) ; United States
    Chemical Substances Chickenpox Vaccine
    Language English
    Publishing date 2005-09-05
    Publishing country Australia
    Document type Comment ; Letter
    ZDB-ID 186082-3
    ISSN 1326-5377 ; 0025-729X
    ISSN (online) 1326-5377
    ISSN 0025-729X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Effectiveness of Acellular Pertussis Vaccine in Older Adults: Nested Matched Case-control Study.

    Liu, Bette C / He, Wen-Qiang / Newall, Anthony T / Quinn, Helen E / Bartlett, Mark / Hayen, Andrew / Sheppeard, Vicky / Rose, Nectarios / Macintyre, C Raina / Mcintyre, Peter

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2019  Volume 71, Issue 2, Page(s) 340–350

    Abstract: Background: Despite recommendations that older adults receive acellular pertussis vaccines, data on direct effectiveness in adults aged over 50 years are sparse.: Methods: A case-control study nested within an adult cohort. Cases were identified from ...

    Abstract Background: Despite recommendations that older adults receive acellular pertussis vaccines, data on direct effectiveness in adults aged over 50 years are sparse.
    Methods: A case-control study nested within an adult cohort. Cases were identified from linked pertussis notifications and each matched to 3 controls on age, sex, and cohort recruitment date. Cases and controls were invited to complete a questionnaire, with verification of vaccination status by their primary care provider. Vaccine effectiveness (VE) was estimated by conditional logistic regression, with adjustment for reported contact with children and area of residence.
    Results: Of 1112 notified cases in the cohort, we had complete data for 333 cases and 506 controls. Among 172 PCR-diagnosed cases (mean age, 61 years), 11.2% versus 19.5% of controls had provider-verified pertussis vaccination, on average, 3.2 years earlier. Adjusted VE against PCR-diagnosed pertussis was 52% (95% CI, 15-73%), nonsignificantly higher if vaccinated within 2 years (63%; -5-87%). Adjusted VE was similar in adults born before 1950, presumed primed by natural infection (51%; -8-77%) versus those born 1950 or later who may have received whole-cell pertussis vaccine (53%; -11-80%) (P-heterogeneity = 0.9). Among 156 cases identified by single-point serology, adjusted VE was -55% (-177-13%).
    Conclusions: We found modest protection against PCR-confirmed pertussis among older adults (mean age, 61 years; range, 46-81 years) within 5 years after acellular vaccine. The most likely explanation for the markedly divergent VE estimate from cases identified by single-titer serology is misclassification arising from limited diagnostic specificity in our setting.
    MeSH term(s) Aged ; Aged, 80 and over ; Case-Control Studies ; Child ; Diphtheria-Tetanus-acellular Pertussis Vaccines ; Humans ; Middle Aged ; Pertussis Vaccine ; Vaccination ; Vaccines, Acellular ; Whooping Cough/epidemiology ; Whooping Cough/prevention & control
    Chemical Substances Diphtheria-Tetanus-acellular Pertussis Vaccines ; Pertussis Vaccine ; Vaccines, Acellular
    Language English
    Publishing date 2019-09-10
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciz821
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  3. Article ; Online: Long-term Impact of Pneumococcal Conjugate Vaccines on Invasive Disease and Pneumonia Hospitalizations in Indigenous and Non-Indigenous Australians.

    Meder, Kelley N / Jayasinghe, Sanjay / Beard, Frank / Dey, Aditi / Kirk, Martyn / Cook, Heather / Strachan, Janet / Sintchenko, Vitali / Smith, Helen / Giele, Carolien / Howden, Benjamin / Krause, Vicki / Mcintyre, Peter

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

    2019  Volume 70, Issue 12, Page(s) 2607–2615

    Abstract: Background: Universal pneumococcal conjugate vaccine (PCV) programs began in Indigenous Australian children in 2001 and all children in 2005, changing to 13-valent PCV (PCV13) in 2011. We used laboratory data for invasive pneumococcal disease (IPD) and ... ...

    Abstract Background: Universal pneumococcal conjugate vaccine (PCV) programs began in Indigenous Australian children in 2001 and all children in 2005, changing to 13-valent PCV (PCV13) in 2011. We used laboratory data for invasive pneumococcal disease (IPD) and coded hospitalizations for noninvasive pneumococcal community-acquired pneumonia (PnCAP) to evaluate long-term impact.
    Methods: Annual incidence (per 100 000 population) was calculated for age-specific total IPD, PCV13 non-7-valent PCV (PCV7) serotypes, and PnCAP by Indigenous status. Incidence in the pre-universal PCV7 (2002-2004), early PCV7 (2005-2007), pre-PCV13 (2008 to mid-2011), and post-PCV13 (mid-2011 to 2016) periods was used to calculate incidence rate ratios (IRRs).
    Results: In the total population, all-age incidence of IPD declined from 11.8 pre-PCV7 to 7.1 post-PCV13 (IRR, 0.61 [95% confidence interval {CI}, .59-.63]) but for PnCAP declined among ages <1 year (IRR, 0.34 [95% CI, .25-.45]) and 1-4 years (IRR, 0.50 [95% CI, .43-.57]) but increased significantly among age ≥5 years (IRRs, 1.08-1.14). In Indigenous people, baseline PCV13 non-PCV7 IPD incidence was 3-fold higher, amplified by a serotype 1 epidemic in 2011. By 2015-2016, although incidence of IPD and PnCAP in children aged <5 years decreased by 38%, neither decreased in people aged ≥5 years.
    Conclusions: Fifteen years post-PCV and 5 years post-PCV13, direct and indirect impact on IPD and PnCAP differed by age and between Indigenous and non-Indigenous people, with potential implications for long-term PCV impact in comparable settings.Fifteen years after pneumococcal conjugate vaccine (PCV) introduction and 5 years post-PCV13, direct and indirect impact on invasive pneumococcal disease and pneumococcal community-acquired pneumonia differed by age and between Indigenous and non-Indigenous people, with potential implications for long-term PCV impact in comparable settings.
    MeSH term(s) Australia/epidemiology ; Child ; Child, Preschool ; Heptavalent Pneumococcal Conjugate Vaccine ; Hospitalization ; Humans ; Incidence ; Infant ; Pneumococcal Infections/epidemiology ; Pneumococcal Infections/prevention & control ; Pneumococcal Vaccines ; Pneumonia/epidemiology ; Pneumonia/prevention & control ; Serogroup ; Vaccines, Conjugate
    Chemical Substances Heptavalent Pneumococcal Conjugate Vaccine ; Pneumococcal Vaccines ; Vaccines, Conjugate
    Language English
    Publishing date 2019-08-07
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1099781-7
    ISSN 1537-6591 ; 1058-4838
    ISSN (online) 1537-6591
    ISSN 1058-4838
    DOI 10.1093/cid/ciz731
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  4. Article: Palliative care patients in the emergency department.

    Lawson, Beverley J / Burge, Frederick I / Mcintyre, Paul / Field, Simon / Maxwell, David

    Journal of palliative care

    2009  Volume 24, Issue 4, Page(s) 247–255

    Abstract: Although end-of-life care is not a primary function of the emergency department (ED), in reality, many access this department in the later stages of illness. In this study, ED use by patients registered with the Capital Health Integrated Palliative Care ... ...

    Abstract Although end-of-life care is not a primary function of the emergency department (ED), in reality, many access this department in the later stages of illness. In this study, ED use by patients registered with the Capital Health Integrated Palliative Care Service (CHIPCS) is examined and CHIPCS patient characteristics associated with ED use identified. Overall, 27% of patients made at least one ED visit while registered with CHIPCS; 54% of these resulted in a hospital admission. ED visiting was not associated with time of day or day of the week. Multivariate logistic regression results suggest older patients were significantly less likely to make an ED visit. Making an ED visit was associated with hospital death, rural residence (particularly for women), and having a parent or relative other than a spouse or child as the primary caregiver. Further research may suggest strategies to reduce unnecessary ED visits during the end of life.
    MeSH term(s) Aged ; Aged, 80 and over ; Continuity of Patient Care/organization & administration ; Emergency Service, Hospital/statistics & numerical data ; Female ; Health Care Surveys ; Health Services Accessibility ; Home Care Services/organization & administration ; Humans ; Interinstitutional Relations ; Length of Stay/statistics & numerical data ; Logistic Models ; Long-Term Care/organization & administration ; Male ; Multivariate Analysis ; Nova Scotia/epidemiology ; Palliative Care/organization & administration ; Referral and Consultation/organization & administration ; Residence Characteristics/statistics & numerical data ; Retrospective Studies ; Rural Population/statistics & numerical data ; Survival Rate
    Language English
    Publishing date 2009-02-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639326-3
    ISSN 0825-8597
    ISSN 0825-8597
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 207: Show issues

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  5. Article: Pathogenesis and treatment of macrocytic anemia; information obtained with radioactive vitamin B12.

    CONLEY, C L / KREVANS, J R / MCINTYRE, P A / SACHS, M V

    A.M.A. archives of internal medicine

    2003  Volume 98, Issue 5, Page(s) 541–549

    MeSH term(s) Anemia/etiology ; Anemia, Macrocytic ; Anemia, Pernicious/diagnosis ; Corrinoids ; Gastrointestinal Tract/physiology ; Humans ; Vitamin B 12
    Chemical Substances Corrinoids ; Vitamin B 12 (P6YC3EG204)
    Language English
    Publishing date 2003-08-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 211575-x
    ISSN 1538-3679 ; 0888-2479 ; 0003-9926 ; 0730-188X
    ISSN (online) 1538-3679
    ISSN 0888-2479 ; 0003-9926 ; 0730-188X
    DOI 10.1001/archinte.1956.00250290001001
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  6. Article: DYNAMICS AND TREATMENT OF THE PASSIVE-AGGRESSIVE UNDERACHIEVER.

    MCINTYRE, P M

    American journal of psychotherapy

    1964  Volume 18, Page(s) 95–108

    MeSH term(s) Aggression ; Child ; Humans ; Motivation ; Parent-Child Relations ; Personality ; Personality Disorders ; Psychology, Educational ; Psychotherapy ; Schools
    Language English
    Publishing date 1964-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2950-6
    ISSN 0002-9564
    ISSN 0002-9564
    DOI 10.1176/appi.psychotherapy.1964.18.1.95
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  7. Article: Total body irradiation.

    MCINTYRE, P H

    The American journal of nursing

    1961  Volume 61, Page(s) 62–64

    MeSH term(s) Humans ; Radiotherapy/nursing ; Whole-Body Irradiation
    Language English
    Publishing date 1961-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 390780-6
    ISSN 0002-936X
    ISSN 0002-936X
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  8. Article: Hypokaliemia occurring during para-aminosalicylic acid therapy.

    MCINTYRE, P A

    Bulletin of the Johns Hopkins Hospital

    1953  Volume 92, Issue 3, Page(s) 210–221

    MeSH term(s) Aminosalicylic Acid/adverse effects ; Humans ; Hypokalemia ; Potassium/blood
    Chemical Substances Aminosalicylic Acid (5B2658E0N2) ; Potassium (RWP5GA015D)
    Language English
    Publishing date 1953-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 218291-9
    ISSN 0097-1383
    ISSN 0097-1383
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