LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Your last searches

  1. AU="McIntyre, Roger"
  2. AU="Adesanya, T M Ayodele"

Search results

Result 1 - 4 of total 4

Search options

  1. Article ; Online: The `WikiGuidelines' smartphone application: Bridging the gaps in availability of evidence-based smartphone mental health applications.

    Zhang, Melvyn W B / Ho, Roger C M / Mcintyre, Roger S

    Technology and health care : official journal of the European Society for Engineering and Medicine

    2016  Volume 24, Issue 4, Page(s) 587–590

    Abstract: Over the past decade, there have been massive advances in technology. These advances in technology have significantly transformed various aspects of healthcare. The advent of E-health and its influence on healthcare practice also implies that there is a ... ...

    Abstract Over the past decade, there have been massive advances in technology. These advances in technology have significantly transformed various aspects of healthcare. The advent of E-health and its influence on healthcare practice also implies that there is a paradigm shift in the way healthcare professionals work. Conventionally, healthcare professionals would have to refer to books and journals for updates in treatment algorithms, but with the advent of technology, they could access this information via the web or via various smartphone applications on the go. In the field of Psychiatry, one of the commonest mental health disorder to date, with significant morbidity and mortality is that of Major depressive disorder. Routinely, clinicians and healthcare professionals are advised to refer to standard guidelines in guiding them with regards to their treatment options. Given the high prevalence of conditions like Major Depressive Disorder, it is thus of importance that whatever guidelines that clinicians and healthcare professionals refer to are constantly kept up to date, so that patients could benefit from latest evidence based therapy and treatment. A review of the current literature highlights that whilst there are a multitude of smartphone applications designed for mental health care, previous systematic review has highlighted a paucity of evidence based applications. More importantly, current literature with regards to provision of treatment information to healthcare professionals and patients are limited to web-based interventions. It is the aim of this technical note to highlight a methodology to which the authors have conceptualized in the implementation of an evidence based mental health guideline applications, known as the `Wiki Guidelines' smartphone application. The authors hope to illustrate the algorithms behind the development of the application, and how it could be easily updated by the guidelines working group.
    MeSH term(s) Depressive Disorder, Major/therapy ; Health Personnel ; Humans ; Mobile Applications ; Practice Guidelines as Topic ; Psychiatry/methods ; Psychiatry/standards ; Smartphone
    Language English
    Publishing date 2016-07-27
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1159961-3
    ISSN 1878-7401 ; 0928-7329
    ISSN (online) 1878-7401
    ISSN 0928-7329
    DOI 10.3233/THC-161141
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: The efficacy of mind-body (Baduanjin) exercise on self-reported sleep quality and quality of life in elderly subjects with sleep disturbances: a randomized controlled trial.

    Fan, Beifang / Song, Weidong / Zhang, Jihui / Er, Yuliang / Xie, Bo / Zhang, Huimin / Liao, Yuhua / Wang, Chengmin / Hu, Xiaohui / Mcintyre, Roger / Lee, Yena

    Sleep & breathing = Schlaf & Atmung

    2020  Volume 24, Issue 2, Page(s) 695–701

    Abstract: Objectives: To examine the efficacy of a 24-week Baduanjin exercise program on self-reported sleep quality and quality of life in community-dwelling elderly subjects with sleep disturbances.: Methods: Community-dwelling elderly men and women meeting ... ...

    Abstract Objectives: To examine the efficacy of a 24-week Baduanjin exercise program on self-reported sleep quality and quality of life in community-dwelling elderly subjects with sleep disturbances.
    Methods: Community-dwelling elderly men and women meeting criteria for sleep disturbances (i.e., Pittsburgh Sleep Quality of Index (PSQI) score ≥ 5) were recruited and randomized to a Baduanjin exercise intervention group or a control group. Participants in the intervention group completed five 45-min exercise sessions per week for 24 weeks, while those in control group were instructed to maintain their usual lifestyle behaviors.
    Results: A total of 139 participants were enrolled and randomized. Sixty-two of 67 participants in the intervention group (response rate of 92.5%) and 57 of 72 participants (response rate of 79.6%) in the control group completed intervention and follow-up. The intervention group reported significant improvements in overall sleep quality after 24 weeks compared with those randomized to control (PSQI endpoint-to-baseline change = - 2.6 ± 4.0 vs. - 0.5 ± 4.2, time × group interaction p = 0.007). Intervention group participants had higher response rates at both week 12 (23.9% vs. 9.7%, p = 0.025) and week 24 (40.3% vs. 15.3%, p = 0.001) when compared with the control group. There was a trend that the intervention group had increased quality of life (The Short Form Health Survey [SF-36] endpoint=tobaseline change 6.3 ± 10.9 vs. 2.2 ± 10.9, time × group interaction p = 0.06) when compared with the control group.
    Conclusions: Baduanjin exercise is an effective and feasible approach to improve self-reported sleep quality but less likely the quality of life in community-dwelling elderly men and women with sleep disturbances.
    Trial registration: Effect of Baduanjin Exercise on the Elderly's Sleep; http://www.chictr.org.cn/listbycreater.aspx; ChiCTR1800014706, registered 1 January 2018.
    MeSH term(s) Aged ; Case-Control Studies ; Feasibility Studies ; Female ; Humans ; Male ; Mind-Body Therapies/methods ; Observer Variation ; Prospective Studies ; Quality of Life/psychology ; Self Report ; Sleep Apnea, Obstructive/psychology ; Sleep Apnea, Obstructive/therapy ; Sleep Wake Disorders/psychology ; Sleep Wake Disorders/therapy ; Treatment Outcome
    Language English
    Publishing date 2020-01-02
    Publishing country Germany
    Document type Comparative Study ; Journal Article ; Randomized Controlled Trial
    ZDB-ID 1500381-4
    ISSN 1522-1709 ; 1520-9512
    ISSN (online) 1522-1709
    ISSN 1520-9512
    DOI 10.1007/s11325-019-01999-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Antidepressant Medications and Weight Change: A Narrative Review.

    Gill, Hartej / Gill, Barjot / El-Halabi, Sabine / Chen-Li, David / Lipsitz, Orly / Rosenblat, Joshua Daniel / Van Rheenen, Tamsyn E / Rodrigues, Nelson B / Mansur, Rodrigo B / Majeed, Amna / Lui, Leanna M W / Nasri, Flora / Lee, Yena / Mcintyre, Roger S

    Obesity (Silver Spring, Md.)

    2020  Volume 28, Issue 11, Page(s) 2064–2072

    Abstract: Antidepressant medications are the first-line treatment option for moderate to severe major depressive disorder. However, most antidepressants have numerous documented adverse events, including cardiometabolic effects and weight gain, which are major ... ...

    Abstract Antidepressant medications are the first-line treatment option for moderate to severe major depressive disorder. However, most antidepressants have numerous documented adverse events, including cardiometabolic effects and weight gain, which are major public health concerns. Antidepressant agents provide varying risk of associated weight gain, including significant within-class differences. Some agents, such as mirtazapine, show significant levels of weight gain, while others, such as bupropion, demonstrate weight-loss effects. Current findings suggest the role of histamine and serotonin off-target appetite-promoting pathways in adverse weight-gain effects. Therefore, controlling for undesired weight effects is an important consideration for the selection of antidepressants.
    MeSH term(s) Antidepressive Agents/adverse effects ; Antidepressive Agents/pharmacology ; Humans ; Weight Gain/drug effects
    Chemical Substances Antidepressive Agents
    Language English
    Publishing date 2020-10-06
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2230457-5
    ISSN 1930-739X ; 1071-7323 ; 1930-7381
    ISSN (online) 1930-739X
    ISSN 1071-7323 ; 1930-7381
    DOI 10.1002/oby.22969
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article: Treatment-resistant depression in primary care across Canada.

    Rizvi, Sakina J / Grima, Etienne / Tan, Mary / Rotzinger, Susan / Lin, Peter / Mcintyre, Roger S / Kennedy, Sidney H

    Canadian journal of psychiatry. Revue canadienne de psychiatrie

    2014  Volume 59, Issue 7, Page(s) 349–357

    Abstract: Objective: Treatment-resistant depression (TRD) represents a considerable global health concern. The goal of the InSight study was to investigate the prevalence of TRD and to evaluate its clinical characterization and management, compared with ... ...

    Abstract Objective: Treatment-resistant depression (TRD) represents a considerable global health concern. The goal of the InSight study was to investigate the prevalence of TRD and to evaluate its clinical characterization and management, compared with nonresistant depression, in primary care centres.
    Methods: Physicians completed a case report on a consecutive series of patients with major depressive disorder (n = 1212), which captured patient demographics and comorbidity, as well as current and past medication.
    Results: Using failure to respond to at least 2 antidepressants (ADs) from different classes as the definition of TRD, the overall prevalence was 21.7%. There were no differences in prevalence between men and women or among ethnicities. Patients with TRD had longer episode duration, were more likely to receive polypharmacy (for example, psychotropic, lipid-lowering, and antiinflammatory agents), and reported more AD related side effects. Higher rates of disability and comorbidity (axes I to III) were associated with treatment resistance. Obesity and being overweight were also associated with treatment resistance. While the selection and sequencing of pharmacotherapy by family physicians in this sample was in line with recommendations from evidence-based treatment guidelines, the wait time to make a change in treatment was 6 to 8 weeks in both groups, which exceeds guideline recommendations.
    Conclusions: These real-world data demonstrate the high prevalence of TRD in primary care settings, and underscore the substantial burden of illness associated with TRD.
    MeSH term(s) Adult ; Antidepressive Agents/adverse effects ; Antidepressive Agents/therapeutic use ; Canada ; Comorbidity ; Cross-Sectional Studies ; Depressive Disorder, Major/diagnosis ; Depressive Disorder, Major/drug therapy ; Depressive Disorder, Major/epidemiology ; Depressive Disorder, Major/psychology ; Depressive Disorder, Treatment-Resistant/diagnosis ; Depressive Disorder, Treatment-Resistant/drug therapy ; Depressive Disorder, Treatment-Resistant/epidemiology ; Depressive Disorder, Treatment-Resistant/psychology ; Drug Substitution ; Drug Therapy, Combination ; Female ; Guideline Adherence ; Health Surveys ; Humans ; Male ; Middle Aged ; Primary Health Care/statistics & numerical data ; Retrospective Studies
    Chemical Substances Antidepressive Agents
    Language English
    Publishing date 2014-07-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 304227-3
    ISSN 1497-0015 ; 0706-7437 ; 0008-4824
    ISSN (online) 1497-0015
    ISSN 0706-7437 ; 0008-4824
    DOI 10.1177/070674371405900702
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top