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  1. Article ; Online: Tunable terahertz hyperbolic metamaterial slabs and super-resolving hyperlenses.

    Zhang, Hui / Jiao, Zhiyong / Mcleod, Euan

    Applied optics

    2020  Volume 59, Issue 22, Page(s) G64–G70

    Abstract: Terahertz (THz) optics offer the potential to image through objects that are opaque for visible wavelengths and provide unique spectroscopic signatures for a variety of materials and quantum processes. However, the resolution of THz images suffers from ... ...

    Abstract Terahertz (THz) optics offer the potential to image through objects that are opaque for visible wavelengths and provide unique spectroscopic signatures for a variety of materials and quantum processes. However, the resolution of THz images suffers from the long wavelength of THz light compared to visible. Hyperbolic metamaterials provide a possible solution through the creation of super-resolving lenses and offer greater flexibility in effective refractive index than can be provided by natural materials. Most hyperbolic metamaterials function in a narrow bandwidth due to their resonant nature. In search of a broadband material, we simulate a temperature-tunable hyperbolic metamaterial composed of a multilayer stack of alternating layers of high-density polyethylene (HDPE) and indium antimonide (InSb). At a single temperature, negative effective medium permittivity is found over a small bandwidth of 0.09 THz, but by tuning over a 40°C temperature range the bandwidth is increased dramatically to 1.0 THz. Furthermore, we compute the transmission and negative refraction through the multilayer stack and simulate the imaging properties of curved hyperlens stacks using slits as test objects, achieving resolutions as small as 20 µm at 130 µm wavelength, far below the half-wavelength diffraction limit.
    Language English
    Publishing date 2020-08-04
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4522
    ISSN (online) 1539-4522
    DOI 10.1364/AO.391952
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Computational sensing of herpes simplex virus using a cost-effective on-chip microscope.

    Ray, Aniruddha / Daloglu, Mustafa Ugur / Ho, Joslynn / Torres, Avee / Mcleod, Euan / Ozcan, Aydogan

    Scientific reports

    2017  Volume 7, Issue 1, Page(s) 4856

    Abstract: Caused by the herpes simplex virus (HSV), herpes is a viral infection that is one of the most widespread diseases worldwide. Here we present a computational sensing technique for specific detection of HSV using both viral immuno-specificity and the ... ...

    Abstract Caused by the herpes simplex virus (HSV), herpes is a viral infection that is one of the most widespread diseases worldwide. Here we present a computational sensing technique for specific detection of HSV using both viral immuno-specificity and the physical size range of the viruses. This label-free approach involves a compact and cost-effective holographic on-chip microscope and a surface-functionalized glass substrate prepared to specifically capture the target viruses. To enhance the optical signatures of individual viruses and increase their signal-to-noise ratio, self-assembled polyethylene glycol based nanolenses are rapidly formed around each virus particle captured on the substrate using a portable interface. Holographic shadows of specifically captured viruses that are surrounded by these self-assembled nanolenses are then reconstructed, and the phase image is used for automated quantification of the size of each particle within our large field-of-view, ~30 mm
    MeSH term(s) Cost-Benefit Analysis ; Herpes Simplex/diagnosis ; Holography/methods ; Image Processing, Computer-Assisted/economics ; Image Processing, Computer-Assisted/methods ; Microscopy/economics ; Microscopy/methods ; Sensitivity and Specificity ; Simplexvirus/isolation & purification
    Language English
    Publishing date 2017-07-07
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-017-05124-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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