LIVIVO - Search results -

Search results

Result 1 - 10 of total 42

Search options

Article ; Online: N-803: a double-edged sword in haplo-NK therapy.

Pende, Daniela / Meazza, Raffaella

2022 Volume 139, Issue 8, Page(s) 1122–1124

MeSH term(s)	Killer Cells, Natural ; Recombinant Fusion Proteins
Chemical Substances	ALT-803 ; Recombinant Fusion Proteins
Language	English
Publishing date	2022-02-24
Publishing country	United States
Document type	Editorial ; Comment
ZDB-ID	80069-7
ISSN	1528-0020 ; 0006-4971
ISSN (online)	1528-0020
ISSN	0006-4971
DOI	10.1182/blood.2021014789
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Uh III Zs.140: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MO 364: Show issues

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Report from the Eleventh Killer Immunoglobulin-like Receptor (KIR) Workshop: Novel insights on KIR polymorphism, ligand recognition, expression and function.

Falco, Michela / Sivori, Simona / Meazza, Raffaella / Pende, Daniela

HLA

2019 Volume 94, Issue 2, Page(s) 100–110

Abstract: The Eleventh Killer Immunoglobulin-like Receptor (KIR) Workshop was held in Camogli (Genoa, Italy) in October 2018. This congress brought together 113 participants working on KIR field. Fifty-eight studies have been presented, the majority of which ... ...

Abstract	The Eleventh Killer Immunoglobulin-like Receptor (KIR) Workshop was held in Camogli (Genoa, Italy) in October 2018. This congress brought together 113 participants working on KIR field. Fifty-eight studies have been presented, the majority of which included unpublished data. Thus, KIR workshop, allowing the meeting of people sharing their knowledge and experience in a friendly atmosphere, still represents a special event of fruitful discussion and exchange of novel breakthrough, results, and ideas. In this report, we summarize all the scientific contributions highlighting the most recent advances in KIR field. Forty abstracts presented at the KIR Workshop are published in this issue.
MeSH term(s)	Biological Evolution ; Disease/genetics ; Genetics, Population ; Histocompatibility Testing ; Humans ; Ligands ; Polymorphism, Genetic ; Receptors, KIR/genetics ; Transplantation
Chemical Substances	Ligands ; Receptors, KIR
Language	English
Publishing date	2019-06-24
Publishing country	England
Document type	Congress
ZDB-ID	2845111-9
ISSN	2059-2310 ; 2059-2302
ISSN (online)	2059-2310
ISSN	2059-2302
DOI	10.1111/tan.13608
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 661: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Epitope characterization of a monoclonal antibody that selectively recognizes KIR2DL1 allotypes.

Falco, Michela / Meazza, Raffaella / Alicata, Claudia / Canevali, Paolo / Muntasell, Aura / Bottino, Cristina / Moretta, Lorenzo / Pende, Daniela / Lopez-Botet, Miguel

HLA

2022 Volume 100, Issue 2, Page(s) 107–118

Abstract: Killer immunoglobulin-like receptor (KIR) genes code for a family of inhibitory and activating receptors, finely tuning NK cell function. Numerous studies reported the relevance of KIR allelic polymorphism on KIR expression, ligand affinity, and strength ...

Abstract	Killer immunoglobulin-like receptor (KIR) genes code for a family of inhibitory and activating receptors, finely tuning NK cell function. Numerous studies reported the relevance of KIR allelic polymorphism on KIR expression, ligand affinity, and strength in signal transduction. Although KIR variability, including gene copy number and allelic polymorphism, in combination with HLA class I polymorphism, impacts both KIR expression and NK cell education, only a precise phenotypic analysis can define the size of the different KIR
MeSH term(s)	Alleles ; Antibodies, Monoclonal ; Epitopes ; HLA-C Antigens/genetics ; Humans ; Killer Cells, Natural ; Receptors, KIR ; Receptors, KIR2DL1/genetics
Chemical Substances	Antibodies, Monoclonal ; Epitopes ; HLA-C Antigens ; KIR2DL1 protein, human ; Receptors, KIR ; Receptors, KIR2DL1
Language	English
Publishing date	2022-06-09
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2845111-9
ISSN	2059-2310 ; 2059-2302
ISSN (online)	2059-2310
ISSN	2059-2302
DOI	10.1111/tan.14630
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 661: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: 2B4 dysfunction in XLP1 NK cells: More than inability to control EBV infection.

Pende, Daniela / Meazza, Raffaella / Marcenaro, Stefania / Aricò, Maurizio / Bottino, Cristina

Clinical immunology (Orlando, Fla.)

2018 Volume 204, Page(s) 31–36

Abstract: X-linked lymphoproliferative disease 1 (XLP1) is a monogenic disorder caused by mutations in SH2D1A, resulting in the absence/dysfunction of the signaling lymphocyte activation molecule (SLAM)-associated protein (SAP). Consequently, SLAM receptors as 2B4 ...

Abstract	X-linked lymphoproliferative disease 1 (XLP1) is a monogenic disorder caused by mutations in SH2D1A, resulting in the absence/dysfunction of the signaling lymphocyte activation molecule (SLAM)-associated protein (SAP). Consequently, SLAM receptors as 2B4 (CD244) and NTB-A (SLAMF6), upon ligand engagement, exert inhibitory instead of activating function. This causes an immune dysfunction that is worsened by the selective inability of NK and T cells to kill EBV-infected B cells with dramatic clinical sequelae (e.g. fulminant mononucleosis, hyperinflammation, lymphoma). Here we outline recent findings on the interplay between inhibitory 2B4 and the various activating receptors in NK cells. 2B4 engagement selectively blocks ITAM-dependent activating receptors as NCR and CD16, while it does not affect NKG2D and DNAM-1. Furthermore, inhibitory 2B4 participates to NK cell education, as highlighted by the existence in XLP1 patients of a large subset of fully functional NK cells that lack self-HLA specific inhibitory receptors and exert autoreactivity against mature dendritic cells.
MeSH term(s)	Animals ; Epstein-Barr Virus Infections/immunology ; Humans ; Immunologic Deficiency Syndromes/immunology ; Immunologic Deficiency Syndromes/metabolism ; Killer Cells, Natural/immunology ; Killer Cells, Natural/metabolism ; Lymphoproliferative Disorders/immunology ; Lymphoproliferative Disorders/metabolism ; Male ; Signaling Lymphocytic Activation Molecule Family/immunology ; Signaling Lymphocytic Activation Molecule Family/metabolism
Chemical Substances	CD244 protein, human ; Signaling Lymphocytic Activation Molecule Family
Language	English
Publishing date	2018-11-02
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	1459903-x
ISSN	1521-7035 ; 1521-6616
ISSN (online)	1521-7035
ISSN	1521-6616
DOI	10.1016/j.clim.2018.10.022
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 880: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Donor selection for adoptive immunotherapy with NK cells in AML patients: Comparison between analysis of lytic NK cell clones and phenotypical identification of alloreactive NK cell repertoire.

Meazza, Raffaella / Ruggeri, Loredana / Guolo, Fabio / Minetto, Paola / Canevali, Paolo / Loiacono, Fabrizio / Ciardelli, Sara / Bo, Alessandra / Luchetti, Silvia / Serio, Alberto / Zannoni, Letizia / Retière, Christelle / Colomar-Carando, Natalia / Parisi, Sarah / Curti, Antonio / Lemoli, Roberto M / Pende, Daniela

Frontiers in immunology

2023 Volume 14, Page(s) 1111419

Abstract: Natural killer (NK) cell-based adoptive immunotherapy in leukemia patients is an emerging field of interest based on clinical evidence of efficacy and safety. Elderly acute myeloid leukemia (AML) patients have been successfully treated with NK cells from ...

Abstract	Natural killer (NK) cell-based adoptive immunotherapy in leukemia patients is an emerging field of interest based on clinical evidence of efficacy and safety. Elderly acute myeloid leukemia (AML) patients have been successfully treated with NK cells from HLA-haploidentical donors, especially when high amounts of alloreactive NK cells were infused. The aim of this study was comparing two approaches to define the size of alloreactive NK cells in haploidentical donors for AML patients recruited in two clinical trials with the acronym "NK-AML" (NCT03955848), and "MRD-NK". The standard methodology was based on the frequency of NK cell clones capable of lysing the related patient-derived cells. The alternative approach consisted of the phenotypic identification of freshly derived NK cells expressing, as inhibitory receptors, only the inhibitory KIR(s) specific for the mismatched KIR-Ligand(s) (HLA-C1, HLA-C2, HLA-Bw4). However, in KIR2DS2
MeSH term(s)	Aged ; Humans ; Donor Selection ; Leukocytes, Mononuclear ; Immunotherapy, Adoptive ; Reproducibility of Results ; Leukemia, Myeloid, Acute/therapy ; Killer Cells, Natural ; Clone Cells
Language	English
Publishing date	2023-02-14
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2023.1111419
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Exploiting Natural Killer Cell Engagers to Control Pediatric B-cell Precursor Acute Lymphoblastic Leukemia.

Colomar-Carando, Natalia / Gauthier, Laurent / Merli, Pietro / Loiacono, Fabrizio / Canevali, Paolo / Falco, Michela / Galaverna, Federica / Rossi, Benjamin / Bosco, Frédéric / Caratini, Mélody / Mingari, Maria Cristina / Locatelli, Franco / Vivier, Eric / Meazza, Raffaella / Pende, Daniela

Cancer immunology research

2022 Volume 10, Issue 3, Page(s) 291–302

Abstract: Natural killer (NK) cells represent a promising cell type in antitumor immunotherapy for efficacy and safety, particularly in the treatment of hematologic malignancies. NK cells have been shown to exert antileukemia activity in the context of ... ...

Abstract	Natural killer (NK) cells represent a promising cell type in antitumor immunotherapy for efficacy and safety, particularly in the treatment of hematologic malignancies. NK cells have been shown to exert antileukemia activity in the context of haploidentical hematopoietic stem cell transplantation (haplo-HSCT). Products have been developed to boost the activation of NK cells only when cross-linked by tumor cells, avoiding any off-target effect. Here, we tested the in vitro effect of different NK-cell engagers (NKCE), which trigger either NKp46 or NKp30 together with CD16A, and target either CD19 or CD20 to induce killing of pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL). Target cells were NALM-16 and MHH-CALL-4 cell lines and four primary leukemias, while effector cells were resting NK cells derived from healthy donors and pediatric patients with leukemia after αβT/B-depleted haplo-HSCT. The NK cell-resistant MHH-CALL-4 was efficiently killed using all NKCEs. Boosting of NK activity against MHH-CALL-4 was also evident by degranulation and IFNγ production. Because of the lack of CD20 and high expression of CD19 on primary BCP-ALL, we focused on NKCEs targeting CD19. NKp46- and NKp30-based NKCEs displayed similar potency at inducing NK-cell activity, even when challenged with primary BCP-ALL blasts. Their efficacy was shown also using NK cells derived from transplanted patients. NKCE-induced activation against BCP-ALL can override HLA-specific inhibitory interactions, although the strongest response was observed by the alloreactive NK-cell subset. These data support the therapeutic use of NKp46/CD16A/CD19-NKCE to fight refractory/relapsed leukemia in pretransplantation or posttransplantation settings.
MeSH term(s)	Antigens, CD19/metabolism ; Child ; Hematopoietic Stem Cell Transplantation ; Humans ; Immunotherapy ; Killer Cells, Natural ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/pathology
Chemical Substances	Antigens, CD19
Language	English
Publishing date	2022-01-22
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2732489-8
ISSN	2326-6074 ; 2326-6066
ISSN (online)	2326-6074
ISSN	2326-6066
DOI	10.1158/2326-6066.CIR-21-0843
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 7022: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Characterization of KIR

Meazza, Raffaella / Falco, Michela / Canevali, Paolo / Loiacono, Fabrizio / Colomar-Carando, Natalia / Muntasell, Aura / Rea, Anna / Mingari, Maria Cristina / Locatelli, Franco / Moretta, Lorenzo / Lopez-Botet, Miguel / Pende, Daniela

HLA

2022 Volume 100, Issue 2, Page(s) 119–132

Abstract: The phenotypic identification of different NK cell subsets allows more in-depth characterization of KIR repertoire and function, which are of potential interest in KIR and disease association studies. KIR genes are highly polymorphic, but a great ... ...

Abstract	The phenotypic identification of different NK cell subsets allows more in-depth characterization of KIR repertoire and function, which are of potential interest in KIR and disease association studies. KIR genes are highly polymorphic, but a great homology exists among the various sequences and few monoclonal antibodies (mAbs) specifically recognize a single KIR. This is the case of HP-DM1 which was demonstrated by analysis of cell transfectants and epitope mapping to be exclusively KIR2DL1-specific, covering all allotypes identified to date, except for KIR2DL1022 and 020, and also to react with KIR2DS1*013. Here, we compared in immunofluorescence analyses the staining of HP-DM1 with other available mAbs to precisely identify KIR2DL1
MeSH term(s)	Alleles ; Antibodies, Monoclonal/metabolism ; Genes, MHC Class I ; HLA-C Antigens ; Humans ; Killer Cells, Natural ; Receptors, KIR ; Receptors, KIR2DL1/genetics
Chemical Substances	Antibodies, Monoclonal ; HLA-C Antigens ; KIR2DL1 protein, human ; Receptors, KIR ; Receptors, KIR2DL1
Language	English
Publishing date	2022-05-15
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2845111-9
ISSN	2059-2310 ; 2059-2302
ISSN (online)	2059-2310
ISSN	2059-2302
DOI	10.1111/tan.14640
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 661: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Isolation, Expansion, and Characterization of Natural Killer Cells and Their Precursors as a Tool to Study Cancer Immunosurveillance.

Parodi, Monica / Meazza, Raffaella / Vitale, Chiara / Pietra, Gabriella / Carrega, Paolo / Vitale, Massimo

Methods in molecular biology (Clifton, N.J.)

2018 Volume 1884, Page(s) 87–117

Abstract: This chapter will describe the current methodologies to isolate and expand NK cells from Peripheral Blood (PB) or tissues for "in vitro" studies, including NK cell antitumor immune function. In addition, methods to induce NK cell maturation, ... ...

Abstract	This chapter will describe the current methodologies to isolate and expand NK cells from Peripheral Blood (PB) or tissues for "in vitro" studies, including NK cell antitumor immune function. In addition, methods to induce NK cell maturation, differentiation, and expansion from CD34
MeSH term(s)	Antigens, CD34/metabolism ; Cell Differentiation/immunology ; Cell Separation/instrumentation ; Cell Separation/methods ; Cells, Cultured ; Cytokines/immunology ; Cytokines/metabolism ; Fetal Blood/cytology ; Flow Cytometry/instrumentation ; Flow Cytometry/methods ; Fluorescent Dyes/chemistry ; Humans ; Immunologic Surveillance ; Killer Cells, Natural/immunology ; Killer Cells, Natural/metabolism ; Lymphocyte Subsets/immunology ; Lymphocyte Subsets/metabolism ; Neoplasms/immunology ; Precursor Cells, T-Lymphoid/physiology ; Primary Cell Culture/instrumentation ; Primary Cell Culture/methods
Chemical Substances	Antigens, CD34 ; Cytokines ; Fluorescent Dyes
Language	English
Publishing date	2018-11-16
Publishing country	United States
Document type	Journal Article
ISSN	1940-6029
ISSN (online)	1940-6029
DOI	10.1007/978-1-4939-8885-3_6
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: NK Cell-Based Immunotherapy for Hematological Malignancies.

Sivori, Simona / Meazza, Raffaella / Quintarelli, Concetta / Carlomagno, Simona / Della Chiesa, Mariella / Falco, Michela / Moretta, Lorenzo / Locatelli, Franco / Pende, Daniela

Journal of clinical medicine

2019 Volume 8, Issue 10

Abstract: Natural killer (NK) lymphocytes are an integral component of the innate immune system and represent important effector cells in cancer immunotherapy, particularly in the control of hematological malignancies. Refined knowledge of NK cellular and ... ...

Abstract	Natural killer (NK) lymphocytes are an integral component of the innate immune system and represent important effector cells in cancer immunotherapy, particularly in the control of hematological malignancies. Refined knowledge of NK cellular and molecular biology has fueled the interest in NK cell-based antitumor therapies, and recent efforts have been made to exploit the high potential of these cells in clinical practice. Infusion of high numbers of mature NK cells through the novel graft manipulation based on the selective depletion of T cells and CD19
Language	English
Publishing date	2019-10-16
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm8101702
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: TCRαβ/CD19 cell-depleted HLA-haploidentical transplantation to treat pediatric acute leukemia: updated final analysis.

Merli, Pietro / Algeri, Mattia / Galaverna, Federica / Bertaina, Valentina / Lucarelli, Barbarella / Boccieri, Emilia / Becilli, Marco / Quagliarella, Francesco / Rosignoli, Chiara / Biagini, Simone / Girolami, Elia / Meschini, Antonella / Del Principe, Giovanna / Sborgia, Raffaella / Catanoso, Maria Luigia / Carta, Roberto / Strocchio, Luisa / Pinto, Rita Maria / Buldini, Barbara /

Falco, Michela / Meazza, Raffaella / Pende, Daniela / Andreani, Marco / Li Pira, Giuseppina / Pagliara, Daria / Locatelli, Franco

Blood

2023 Volume 143, Issue 3, Page(s) 279–289

Abstract: Abstract: TCRαβ/CD19 cell depletion is a promising graft manipulation technique frequently used in the context of human leukocyte antigen (HLA)-haploidentical hematopoietic stem cell transplantation (HSCT). We previously reported the results of a phase ... ...

Abstract	Abstract: TCRαβ/CD19 cell depletion is a promising graft manipulation technique frequently used in the context of human leukocyte antigen (HLA)-haploidentical hematopoietic stem cell transplantation (HSCT). We previously reported the results of a phase I-II clinical trial (NCT01810120) to assess the safety and the efficacy of this type of exvivo T-cell depletion in 80 children with acute leukemia, showing promising survival outcomes. We now report an updated analysis on a cohort of 213 children with a longer follow-up (median, 47.6 months for surviving patients). With a 5-year cumulative incidence of nonrelapse mortality of 5.2% (95% confidence interval [CI], 2.8%-8.8%) and a cumulative incidence of relapse of 22.7% (95% CI, 16.9%-29.2%), projected 10-year overall and disease-free survival (DFS) were 75.4% (95% CI, 68.6%-80.9%) and 71.6% (95% CI, 64.4%-77.6%), respectively. Cumulative incidence of both grade II-IV acute and chronic graft-versus-host disease were low (14.7% and 8.1%, respectively). In a multivariable analysis for DFS including type of disease, use of total body irradiation in the conditioning regimen (hazard ratio [HR], 0.5; 95% CI, 0.26-0.98; P = .04), disease status at HSCT (complete remission [CR] ≥3 vs CR 1/2; HR, 2.23; 95% CI, 1.20-4.16; P = .01), and high levels of pre-HSCT minimal residual disease (HR, 2.09; 95% CI, 1.01-4.33; P = .04) were independently associated with outcome. In summary, besides confirming the good outcome results already reported (which are almost superimposable on those of transplant from HLA-matched donors), this clinical update allows the identification of patients at higher risk of treatment failure for whom personalized approaches, aimed at reducing the risk of relapse, are warranted.
MeSH term(s)	Child ; Humans ; Receptors, Antigen, T-Cell, alpha-beta ; Transplantation, Haploidentical/adverse effects ; Graft vs Host Disease ; Leukemia, Myeloid, Acute ; HLA Antigens ; Hematopoietic Stem Cell Transplantation/methods ; Histocompatibility Antigens Class II ; Recurrence ; Transplantation Conditioning/methods ; Retrospective Studies
Chemical Substances	Receptors, Antigen, T-Cell, alpha-beta ; HLA Antigens ; Histocompatibility Antigens Class II
Language	English
Publishing date	2023-09-22
Publishing country	United States
Document type	Journal Article
ZDB-ID	80069-7
ISSN	1528-0020 ; 0006-4971
ISSN (online)	1528-0020
ISSN	0006-4971
DOI	10.1182/blood.2023021336
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Uh III Zs.140: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MO 364: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito