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  1. Article ; Online: International Prognostic Modeling: A Platform for Collaborative Approach for Patients With Mesothelioma.

    Medina, Cristian G / Xu, Yuan / Ripley, R Taylor

    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

    2023  Volume 18, Issue 12, Page(s) 1618–1620

    MeSH term(s) Humans ; Prognosis ; Lung Neoplasms/therapy ; Mesothelioma, Malignant ; Mesothelioma/therapy ; Pleural Neoplasms/therapy
    Language English
    Publishing date 2023-11-20
    Publishing country United States
    Document type Editorial
    ZDB-ID 2432037-7
    ISSN 1556-1380 ; 1556-0864
    ISSN (online) 1556-1380
    ISSN 1556-0864
    DOI 10.1016/j.jtho.2023.09.1441
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6664: Show issues Location:
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    Zs.MO 652: Show issues

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  2. Article: The Role of Surgery for Oligometastatic Non-Small Cell Lung Cancer.

    Euhus, Caleb J / Ripley, Taylor R / Medina, Cristian G

    Cancers

    2022  Volume 14, Issue 10

    Abstract: Oligometastatic non-small cell lung cancer (NSCLC) is metastatic disease that refers to a limited number of metastatic sites. It is analogous to an intermediate stage of NSCLC, between localized and widely metastatic disease, even though no staging ... ...

    Abstract Oligometastatic non-small cell lung cancer (NSCLC) is metastatic disease that refers to a limited number of metastatic sites. It is analogous to an intermediate stage of NSCLC, between localized and widely metastatic disease, even though no staging criteria establishes this distinction. Oligometastatic NSCLC describes a patient subgroup with limited metastasis to one or a few organs. These patients seem to have a more indolent cancer than those with diffuse metastasis. For these select patients with oligometastatic disease, the use of palliative systemic therapy over local aggressive treatment may be a missed opportunity to improve survival. The clear definition of this subgroup and identification of the best treatment remains the current challenge in the management of the disease. Surgery was the early cornerstone in the treatment of limited disease; however, as modalities such as chemotherapy, stereotactic radiosurgery, and immunotherapy have matured, the role of excision is less clearly defined. There are sparse randomized controlled trials comparing the efficacy of different treatment modalities in patients with oligometastatic NSCLC. However, there is a growing body of retrospective research detailing the prognostic factors that characterize the role of surgery in the management of these patients. This article clarifies the context and definition of the term oligometastatic, as it applies to NSCLC, and reviews the current results in the use of surgery for its management.
    Language English
    Publishing date 2022-05-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers14102524
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Arbuscular mycorrhizal fungi enhance monoterpene production in red clover (Trifolium pratense L.): a potential tool for pest control

    Medina, Cristián / Mutis, Ana / Bardehle, Leonardo / Hormazabal, Emilio / Borie B., Fernando / Aguilera, Paula / Ortega, Fernando / Quiroz, Andrés

    Natural Product Research. 2023 Mar. 19, v. 37, no. 6 p.981-984

    2023  

    Abstract: The possibility of modifying terpene production in plants is a defensive strategy that has been studied in conjunction with their biosynthetic pathways. A biotic factor such as Arbuscular Mycorrhizal Fungi (AMF) could modify terpene production in ... ...

    Abstract The possibility of modifying terpene production in plants is a defensive strategy that has been studied in conjunction with their biosynthetic pathways. A biotic factor such as Arbuscular Mycorrhizal Fungi (AMF) could modify terpene production in Trifolium pratense L. In this work, the enzymatic production of monoterpenes in Superqueli INIA cultivar with two AMF was evaluated via HeadSpace-Gas Chromatography (HS-GC). A significant increase of (S)-limonene was found in plants inoculated with Claroideoglomus claroideum as well as with the AMF mix (genera Scutellospora, Acaulospora and Glomus). Moreover, significant increases in other monoterpenes such as (-)-β-pinene, myrcene, linalool, were observed. Results showed higher monoterpene production capacities in the Superqueli-INIA cultivar, suggesting the participation of monoterpene synthases (MTS). The significant rise of (S)-limonene in red clover plants inoculated with AMF suggests this strategy could be implemented in an agronomical manage for controlling the H. obscurus, the primary pest.
    Keywords Acaulospora ; Claroideoglomus claroideum ; Glomus ; Scutellospora ; Trifolium pratense ; biosynthesis ; biotic factors ; chromatography ; cultivars ; linalool ; myrcene ; pest control ; pests ; research ; vesicular arbuscular mycorrhizae ; Red clover ; monoterpenes ; (S)-limonene ; arbuscular mycorrhizal fungi
    Language English
    Dates of publication 2023-0319
    Size p. 981-984.
    Publishing place Taylor & Francis
    Document type Article ; Online
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2022.2094375
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Arbuscular mycorrhizal fungi enhance monoterpene production in red clover (

    Medina, Cristian / Mutis, Ana / Bardehle, Leonardo / Hormazabal, Emilio / Borie, Fernando / Aguilera, Paula / Ortega, Fernando / Quiroz, Andrés

    Natural product research

    2022  Volume 37, Issue 6, Page(s) 981–984

    Abstract: The possibility of modifying terpene production in plants is a defensive strategy that has been studied in conjunction with their biosynthetic pathways. A biotic factor such as Arbuscular Mycorrhizal Fungi (AMF) could modify terpene production ... ...

    Abstract The possibility of modifying terpene production in plants is a defensive strategy that has been studied in conjunction with their biosynthetic pathways. A biotic factor such as Arbuscular Mycorrhizal Fungi (AMF) could modify terpene production in
    MeSH term(s) Mycorrhizae/metabolism ; Trifolium/metabolism ; Trifolium/microbiology ; Monoterpenes ; Limonene ; Fungi/metabolism ; Terpenes/metabolism ; Plants/metabolism ; Pest Control
    Chemical Substances Monoterpenes ; Limonene (9MC3I34447) ; Terpenes
    Language English
    Publishing date 2022-06-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2022.2094375
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Pleurectomy and decortication are associated with better survival for bicavitary cytoreductive surgery for mesothelioma compared with extrapleural pneumonectomy.

    Ripley, R Taylor / Holmes, Hudson M / Whitlock, Richard S / Groth, Shawn S / Medina, Cristian G / Choi, Eugene A / Burt, Bryan M / Sugarbaker, Paul H

    The Journal of thoracic and cardiovascular surgery

    2022  Volume 165, Issue 5, Page(s) 1722–1730

    Abstract: Objectives: Mesothelioma is a nearly uniformly fatal tumor. Multimodality therapy including cytoreductive surgery and chemotherapy is associated with long-term survival in some patients. Cytoreductive surgery for thoracic disease includes a lung-sparing ...

    Abstract Objectives: Mesothelioma is a nearly uniformly fatal tumor. Multimodality therapy including cytoreductive surgery and chemotherapy is associated with long-term survival in some patients. Cytoreductive surgery for thoracic disease includes a lung-sparing operation called an "extended pleurectomy/decortication" or a lung-sacrificing surgery called an "extrapleural pneumonectomy." The benefit of cytoreductive surgery for bicavitary disease (chest and abdomen) is poorly understood. Our objective was to evaluate the long-term survivals for patients undergoing cytoreductive surgery for bicavitary disease and to determine whether any prognostic factors were associated with outcome.
    Methods: We reviewed our Institutional Review Board-approved, institutional, International Association for the Study of Lung Cancer Mesothelioma Staging Project database. Inclusion criteria were all patients who underwent cytoreductive surgery for bicavitary disease. Overall survival was calculated by Kaplan-Meier methodology. All International Association for the Study of Lung Cancer database elements were evaluated by univariable analysis.
    Results: From February 2014 to August 2021, 440 patients with mesothelioma were evaluated. Fourteen patients (3%) underwent cytoreductive surgery of both chest and abdomen as a planned 2-stage operation. Most patients (13/14; 93%) underwent chest surgery before abdomen surgery. For the entire cohort, the median overall survival was 33.6 months with a 5-year survival of 20%. Extended pleurectomy/decortication was associated with a better outcome compared with extrapleural pneumonectomy, with median overall survivals of 58.2 versus 13.5 months, respectively.
    Conclusions: For a highly selected group of patients with bicavitary mesothelioma, long-term survival can be achieved with an aggressive, staged surgical approach. The patients who undergo extended pleurectomy/decortication with preservation of the lung appear to have more favorable outcomes compared with patients undergoing extrapleural pneumonectomy.
    MeSH term(s) Humans ; Pneumonectomy/adverse effects ; Pneumonectomy/methods ; Cytoreduction Surgical Procedures/adverse effects ; Pleural Neoplasms ; Treatment Outcome ; Retrospective Studies ; Mesothelioma, Malignant ; Mesothelioma ; Lung Neoplasms/surgery
    Language English
    Publishing date 2022-12-14
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 3104-5
    ISSN 1097-685X ; 0022-5223
    ISSN (online) 1097-685X
    ISSN 0022-5223
    DOI 10.1016/j.jtcvs.2022.11.035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uk I Zs.104: Show issues Location:
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  6. Article ; Online: Electron energy loss and angular asymmetry induced by elastic scattering in superfluid helium nanodroplets.

    Asmussen, Jakob D / Sishodia, Keshav / Bastian, Björn / Abid, Abdul R / Ben Ltaief, Ltaief / Pedersen, Henrik B / De, Subhendu / Medina, Cristian / Pal, Nitish / Richter, Robert / Fennel, Thomas / Krishnan, Sivarama / Mudrich, Marcel

    Nanoscale

    2023  Volume 15, Issue 34, Page(s) 14025–14031

    Abstract: Helium nanodroplets are ideal model systems to unravel the complex interaction of condensed matter with ionizing radiation. Here we study the effect of purely elastic electron scattering on angular and energy distributions of photoelectrons emitted from ... ...

    Abstract Helium nanodroplets are ideal model systems to unravel the complex interaction of condensed matter with ionizing radiation. Here we study the effect of purely elastic electron scattering on angular and energy distributions of photoelectrons emitted from He nanodroplets of variable size (10-10
    Language English
    Publishing date 2023-09-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2515664-0
    ISSN 2040-3372 ; 2040-3364
    ISSN (online) 2040-3372
    ISSN 2040-3364
    DOI 10.1039/d3nr03295g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: [Is the scientific name important in medical journals?: Experience in a Colombian university Is the scientific name important in medical journals?]

    Ortiz-Martinez, Yeimer / Pulido-Medina, Cristian

    Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina)

    2017  Volume 74, Issue 2, Page(s) 168–169

    Abstract: ...

    Abstract .
    MeSH term(s) Authorship/standards ; Colombia ; Humans ; Information Storage and Retrieval/methods ; Names ; Periodicals as Topic ; Universities
    Language Spanish
    Publishing date 2017
    Publishing country Argentina
    Document type Journal Article
    ZDB-ID 390127-0
    ISSN 1853-0605 ; 0014-6722 ; 0301-7281
    ISSN (online) 1853-0605
    ISSN 0014-6722 ; 0301-7281
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Optimization of enzymatic parameters for the production of formononetin from red clover (

    Muñoz, María Teresa / Maldonado, Vanessa / Herrera, Wence / Mutis, Ana / Bardehle, Leonardo / Medina, Cristian / Hormazábal, Emilio / Ortega, Fernando / Quiroz, Andrés

    Natural product research

    2021  Volume 36, Issue 18, Page(s) 4719–4724

    Abstract: Trifolium ... ...

    Abstract Trifolium pratense
    MeSH term(s) Isoflavones/chemistry ; Trifolium/chemistry ; Trifolium/metabolism
    Chemical Substances Isoflavones ; formononetin (295DQC67BJ)
    Language English
    Publishing date 2021-11-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2185747-7
    ISSN 1478-6427 ; 1478-6419
    ISSN (online) 1478-6427
    ISSN 1478-6419
    DOI 10.1080/14786419.2021.2002324
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Insecticidal, Repellent and Antifeedant Activity of Essential Oils from

    Espinoza, Javier / Medina, Cristian / Aniñir, Washington / Escobar-Bahamondes, Paul / Ungerfeld, Emilio / Urzúa, Alejandro / Quiroz, Andrés

    Molecules (Basel, Switzerland)

    2021  Volume 26, Issue 22

    Abstract: Haematobia ... ...

    Abstract Haematobia irritans
    MeSH term(s) Animals ; Cattle ; Cupressaceae/chemistry ; Insect Repellents/chemistry ; Insect Repellents/pharmacology ; Insecticides/chemistry ; Insecticides/pharmacology ; Muscidae/metabolism ; Myrtaceae/chemistry ; Oils, Volatile/chemistry ; Oils, Volatile/pharmacology ; Plant Leaves/chemistry
    Chemical Substances Insect Repellents ; Insecticides ; Oils, Volatile
    Language English
    Publishing date 2021-11-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules26226936
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 81: Show issues

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  10. Article ; Online: Epipericardial Fat Necrosis: Sonographic Findings and Their Correlation With Computed Tomography.

    Díaz, Jorge / Alegría, Julia / Pérez, Daniel / Medina, Cristián

    Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine

    2016  Volume 35, Issue 10, Page(s) 2279–2283

    Abstract: Epipericardial fat necrosis is a rare cause of chest pain. It presents as pleuritic pain in an otherwise healthy patient. Computed tomography has proved to be the most effective diagnostic imaging technique because of its ability to reveal typical ... ...

    Abstract Epipericardial fat necrosis is a rare cause of chest pain. It presents as pleuritic pain in an otherwise healthy patient. Computed tomography has proved to be the most effective diagnostic imaging technique because of its ability to reveal typical alterations in the cardiophrenic space. As far as we know, sonographic findings concerning this entity have not been reported in the literature. We report 4 cases admitted to our institutional emergency department with chest pain. Among other tests, chest wall sonography was requested in these patients and showed special findings that should be evaluated with chest computed tomography.
    MeSH term(s) Adult ; Diagnosis, Differential ; Fat Necrosis/diagnostic imaging ; Female ; Humans ; Male ; Middle Aged ; Pericardium/diagnostic imaging ; Reproducibility of Results ; Tomography, X-Ray Computed ; Ultrasonography ; Young Adult
    Language English
    Publishing date 2016-10
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 604829-8
    ISSN 1550-9613 ; 0278-4297
    ISSN (online) 1550-9613
    ISSN 0278-4297
    DOI 10.7863/ultra.15.11087
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 495: Show issues

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