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  1. Article ; Online: Detection of Blastomyces gilchristii via metagenomic sequencing in outbreak-associated soils.

    Linz, Alexandra M / Anderson, Jennifer L / Meece, Jennifer K

    Medical mycology

    2024  Volume 62, Issue 1

    Abstract: Cases of blastomycosis, a serious fungal disease globally rare but endemic to North America, can appear both sporadically and in outbreaks. Tracing these outbreaks to their environment has traditionally used culturing and polymerase chain reaction. Here, ...

    Abstract Cases of blastomycosis, a serious fungal disease globally rare but endemic to North America, can appear both sporadically and in outbreaks. Tracing these outbreaks to their environment has traditionally used culturing and polymerase chain reaction. Here, we present our method for metagenomic detection of Blastomyces in a 2015 outbreak soil sample from central Wisconsin. By sequencing this sample to multiple depths, we simulated the minimum required depth to detect Blastomyces in this outbreak. Our methods and recommendations can be used to identify the sources of blastomycosis during outbreaks and to learn about the ecology of Blastomyces.
    MeSH term(s) Animals ; Blastomyces/genetics ; Blastomycosis/diagnosis ; Blastomycosis/epidemiology ; Blastomycosis/microbiology ; Blastomycosis/veterinary ; Ecology ; Disease Outbreaks
    Language English
    Publishing date 2024-01-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 1421796-x
    ISSN 1460-2709 ; 1369-3786
    ISSN (online) 1460-2709
    ISSN 1369-3786
    DOI 10.1093/mmy/myad140
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 520: Show issues Location:
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  2. Article ; Online: Clinical Presentation of Blastomycosis is Associated With Infecting Species, Not Host Genotype.

    Linz, Alexandra M / Frost, Holly M / Kitchner, Terrie / Anderson, Jennifer L / Meece, Jennifer

    Clinical medicine & research

    2024  Volume 22, Issue 1, Page(s) 6–12

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Humans ; Blastomycosis/diagnosis ; Blastomycosis/genetics ; Blastomyces/genetics ; Genotype ; Ambulatory Care Facilities ; Hotlines
    Language English
    Publishing date 2024-04-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2303793-3
    ISSN 1554-6179 ; 1539-4182
    ISSN (online) 1554-6179
    ISSN 1539-4182
    DOI 10.3121/cmr.2024.1880
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Prevention of Covid-19 with the BNT162b2 and mRNA-1273 Vaccines. Reply.

    Thompson, Mark G / Grant, Lauren / Meece, Jennifer

    The New England journal of medicine

    2021  Volume 385, Issue 19, Page(s) 1819–1821

    MeSH term(s) COVID-19 ; COVID-19 Vaccines ; Humans ; SARS-CoV-2 ; Vaccines
    Chemical Substances COVID-19 Vaccines ; Vaccines ; mRNA-1273 vaccine (EPK39PL4R4) ; BNT162 vaccine (N38TVC63NU)
    Language English
    Publishing date 2021-10-06
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2113575
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Molecular detection of Blastomyces in an air sample from an outbreak associated residence.

    Anderson, Jennifer L / Meece, Jennifer K

    Medical mycology

    2018  Volume 57, Issue 7, Page(s) 897–899

    Abstract: Based on epidemiologic data during a blastomycosis outbreak, exposure within the home was suspected for two case patients that resided together. Soil and air samples were collected from the basement of their residence. Samples were tested for Blastomyces ...

    Abstract Based on epidemiologic data during a blastomycosis outbreak, exposure within the home was suspected for two case patients that resided together. Soil and air samples were collected from the basement of their residence. Samples were tested for Blastomyces by culture and polymerase chain reaction (PCR) to compare with an available clinical isolate. An air sample from the basement of the residence was PCR positive for Blastomyces. Sequence data from the air sample and the outbreak clinical isolate were identified as different Blastomyces spp. Despite this, our findings suggest that the basement was suitable for the growth of Blastomyces and airborne organism was circulating.
    MeSH term(s) Air Microbiology ; Blastomyces/genetics ; Blastomyces/growth & development ; Blastomycosis/microbiology ; Disease Outbreaks ; Housing ; Humans
    Language English
    Publishing date 2018-12-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 1421796-x
    ISSN 1460-2709 ; 1369-3786
    ISSN (online) 1460-2709
    ISSN 1369-3786
    DOI 10.1093/mmy/myy085
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 520: Show issues Location:
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  5. Article: Spontaneous resolution of blastomycosis symptoms caused by

    Anderson, Jennifer L / Frost, Holly M / Meece, Jennifer K

    Medical mycology case reports

    2020  Volume 30, Page(s) 43–45

    Abstract: Given the propensity of blastomycosis to disseminate or reoccur and the inability to predict which infections will experience severe manifestations, nearly all cases of blastomycosis are treated. Although, spontaneous resolution of symptoms is referred ... ...

    Abstract Given the propensity of blastomycosis to disseminate or reoccur and the inability to predict which infections will experience severe manifestations, nearly all cases of blastomycosis are treated. Although, spontaneous resolution of symptoms is referred to generally in the literature, to our knowledge an individual case of this has not been previously reported. We report the spontaneous resolution of blastomycosis symptoms in a 40 year-old Caucasian male.
    Language English
    Publishing date 2020-10-24
    Publishing country Netherlands
    Document type Case Reports
    ISSN 2211-7539
    ISSN 2211-7539
    DOI 10.1016/j.mmcr.2020.10.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Persistent and nonprogressive cutaneous blastomycosis in a pregnant adolescent.

    Anderson, Jennifer L / Hall, Matthew C / Stratman, Erik J / Meece, Jennifer K

    JAAD case reports

    2020  Volume 6, Issue 3, Page(s) 169–171

    Language English
    Publishing date 2020-02-12
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2834220-3
    ISSN 2352-5126
    ISSN 2352-5126
    DOI 10.1016/j.jdcr.2019.08.007
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  7. Article: Incidental findings of blastomycosis lung nodules in five asymptomatic patients.

    Anderson, Jennifer L / Hall, Matthew C / Meece, Jennifer K

    Medical mycology case reports

    2018  Volume 21, Page(s) 63–65

    Abstract: Asymptomatic blastomycosis infections are rarely identified or described in the literature, but are believed to comprise 50% of cases. In this report we describe five sporadic cases of blastomycosis in asymptomatic patients. All of these cases were ... ...

    Abstract Asymptomatic blastomycosis infections are rarely identified or described in the literature, but are believed to comprise 50% of cases. In this report we describe five sporadic cases of blastomycosis in asymptomatic patients. All of these cases were initially identified as incidental findings of lung nodules on CXR or CT. To our knowledge, these are the first detailed descriptions of asymptomatic blastomycosis, occurring as sporadic disease, in the literature.
    Language English
    Publishing date 2018-05-25
    Publishing country Netherlands
    Document type Case Reports
    ISSN 2211-7539
    ISSN 2211-7539
    DOI 10.1016/j.mmcr.2018.05.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Multicenter Clinical Evaluation of Modified Two-Tiered Testing Algorithms for Lyme Disease Using Zeus Scientific Commercial Assays.

    Sfeir, Maroun M / Meece, Jennifer K / Theel, Elitza S / Granger, Dane / Fritsche, Thomas R / Steere, Allen C / Branda, John A

    Journal of clinical microbiology

    2022  Volume 60, Issue 5, Page(s) e0252821

    Abstract: Modified two-tiered testing (MTTT) algorithms for Lyme disease (LD), which involve the sequential use of orthogonal enzyme immunoassays (EIAs) without immunoblotting, are acceptable alternatives to standard two-tiered testing (STTT; EIA followed by ... ...

    Abstract Modified two-tiered testing (MTTT) algorithms for Lyme disease (LD), which involve the sequential use of orthogonal enzyme immunoassays (EIAs) without immunoblotting, are acceptable alternatives to standard two-tiered testing (STTT; EIA followed by immunoblots) provided the EIAs have been FDA-cleared for this intended use. We evaluated four Zeus Scientific LD EIAs used in two distinct MTTT algorithms for FDA review. MTTT 1 used a VlsE1/pepC10 polyvalent EIA followed by a whole-cell sonicate (WCS) polyvalent EIA. MTTT 2 used the same first-tier EIA followed by separate IgM and IgG WCS EIAs. In a retrospective phase, we compared each MTTT algorithm to STTT using archived samples from LD patients or control subjects. In a prospective phase, we used the same algorithms to analyze consecutive excess samples submitted for routine LD serology to three clinical laboratories. For the retrospective phase, MTTTs 1 and 2 were more sensitive (56% and 74%) than STTT (41%;
    MeSH term(s) Algorithms ; Animals ; Antibodies, Bacterial ; Borrelia burgdorferi ; Fishes ; Humans ; Immunoglobulin M ; Lyme Disease ; Prospective Studies ; Retrospective Studies ; Sensitivity and Specificity ; Serologic Tests
    Chemical Substances Antibodies, Bacterial ; Immunoglobulin M
    Language English
    Publishing date 2022-04-14
    Publishing country United States
    Document type Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 390499-4
    ISSN 1098-660X ; 0095-1137
    ISSN (online) 1098-660X
    ISSN 0095-1137
    DOI 10.1128/jcm.02528-21
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1188: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  9. Article ; Online: Surveillance for multidrug resistant Escherichia coli carriage in cattle, dogs and humans reveals predominance of CMY-2, CTX-M-15 and CTX-M-9 groups of β-lactamases.

    Ortiz, Daniel A / Legenza, Laurel M / Olson, Brooke J / Knapp, Cindy C / Killian, Scott B / Meece, Jennifer K / Hall, Matthew C / Fritsche, Thomas R

    Comparative immunology, microbiology and infectious diseases

    2022  Volume 89, Page(s) 101880

    Abstract: Global spread of antimicrobial multidrug resistance (MDR) in human and veterinary medicine relies upon diagnostics, surveillance and stewardship to guide mitigation. Utilizing surveillance of fecal samples from our service area for detecting MDR ... ...

    Abstract Global spread of antimicrobial multidrug resistance (MDR) in human and veterinary medicine relies upon diagnostics, surveillance and stewardship to guide mitigation. Utilizing surveillance of fecal samples from our service area for detecting MDR Escherichia coli carriage in humans (2143), dogs (627), and cattle (130), we found isolates resistant to third/fourth generation cephems present in 3.7 %, 13.1 %, and 51.5 %, respectively. CMY-2, CTX-M-15-like and CTX-M9 group genes in descending order were predominant in all hosts and accounted for 83.3 % of non-wild-type gene targets. MDR carriage mirrored cephem non-susceptibility rates as published in annual antibiograms for humans and dogs; notably, no carbapenem-resistant carriage isolates were detected. Given the scale of MDR E. coli carriage in cattle (14X) and dogs (3.5X) compared to humans, bench-marking of the resistance gene pool by host species utilizing regional One Health surveillance may aid in assessing occupational and geographic risks for acquiring resistance and for monitoring of mitigation strategies.
    MeSH term(s) Animals ; Anti-Bacterial Agents/pharmacology ; Anti-Infective Agents ; Cattle ; Cattle Diseases/epidemiology ; Dog Diseases/epidemiology ; Dogs ; Escherichia coli ; Escherichia coli Infections/epidemiology ; Escherichia coli Infections/veterinary ; Humans ; Microbial Sensitivity Tests/veterinary ; beta-Lactamases/genetics
    Chemical Substances Anti-Bacterial Agents ; Anti-Infective Agents ; beta-Lactamases (EC 3.5.2.6)
    Language English
    Publishing date 2022-09-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 436522-7
    ISSN 1878-1667 ; 0147-9571
    ISSN (online) 1878-1667
    ISSN 0147-9571
    DOI 10.1016/j.cimid.2022.101880
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1443: Show issues Location:
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  10. Article: Racial Differences in Clinical Phenotype and Hospitalization of Blastomycosis Patients.

    Anderson, Jennifer L / Frost, Holly M / King, Jennifer P / Meece, Jennifer K

    Open forum infectious diseases

    2019  Volume 6, Issue 11, Page(s) ofz438

    Abstract: Background: Dimorphic fungal infections, such as blastomycosis, cause significant morbidity and mortality. Historically, blastomycosis studies have focused on non-Hispanic whites, which limits our understanding of the clinical presentation and outcomes ... ...

    Abstract Background: Dimorphic fungal infections, such as blastomycosis, cause significant morbidity and mortality. Historically, blastomycosis studies have focused on non-Hispanic whites, which limits our understanding of the clinical presentation and outcomes for patients of other races and ethnicities. We evaluated whether clinical presentation and disease severity varied across racial and ethnic groups.
    Methods: Blastomycosis patients were identified from Marshfield Clinic Health System and data were abstracted from electronic medical records.
    Results: In total, 477 patients were included. Age differences were observed across race and ethnicity categories (
    Conclusions: Hispanic whites, AIAN, and Asian blastomycosis patients were younger and healthier but more frequently hospitalized. Patients in these racial and ethnic groups may need more aggressive treatment and closer therapeutic monitoring.
    Language English
    Publishing date 2019-10-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2757767-3
    ISSN 2328-8957
    ISSN 2328-8957
    DOI 10.1093/ofid/ofz438
    Database MEDical Literature Analysis and Retrieval System OnLINE

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