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  1. Article ; Online: Discordant expression of maternal SLE in twin pregnancy with a single fetal AV block: A case report.

    Mehdi, M Q / Franco Fuenmayor, M E / Aly, A M

    Journal of neonatal-perinatal medicine

    2022  

    Abstract: There are multiple manifestations in the neonatal period for infants born to mothers with systematic lupus erythematosus (SLE), ranging from cardiac, hematologic and dermatologic abnormalities. Cardiac complications may arise in utero in the form of ... ...

    Abstract There are multiple manifestations in the neonatal period for infants born to mothers with systematic lupus erythematosus (SLE), ranging from cardiac, hematologic and dermatologic abnormalities. Cardiac complications may arise in utero in the form of heart block with a resulting increase in fetal mortality. The fetal conduction system is suspected to be affected by transplacental maternal antibodies, however additional environmental and fetal factors appear to play a role. We describe a rare case of a dichorionic-diamniotic twin pregnancy in which only one twin developed a complete heart block progressing to hydrops fetalis and fetal demise.
    Language English
    Publishing date 2022-04-25
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2435387-5
    ISSN 1878-4429 ; 1934-5798
    ISSN (online) 1878-4429
    ISSN 1934-5798
    DOI 10.3233/NPM-210819
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Intussusception in a child with COVID-19 in the USA

    Bazuaye-Ekwuyasi, E. A. / Camacho, A. C. / Saenz Rios, F. / Torck, A. / Choi, W. J. / Aigbivbalu, E. E. / Mehdi, M. Q. / Shelton, K. J. / Radhakrishnan, G. L. / Radhakrishnan, R. S. / Swischuk, L. E.

    Emerg Radiol

    Abstract: COVID-19, caused by the novel coronavirus strain SARS-CoV-2 that emerged in late 2019, has resulted in a global pandemic COVID-19 was initially believed to occur less frequently in children with relatively mild disease However, severe disease and varied ... ...

    Abstract COVID-19, caused by the novel coronavirus strain SARS-CoV-2 that emerged in late 2019, has resulted in a global pandemic COVID-19 was initially believed to occur less frequently in children with relatively mild disease However, severe disease and varied presentations have been reported in infected children, one of such being intussusception There have only been three reported cases of intussusception in the pediatric population infected with COVID-19 In this paper, we will discuss the management and treatment of a novel fourth case of COVID-19-associated intussusception This case is the first reported in the USA and suggests that COVID-19 may be implicated in the development of intussusception Pediatricians should consider the possibility of intussusception when a child with COVID-19 presents with abdominal pain
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #834006
    Database COVID19

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  3. Article ; Online: Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection

    Nepogodiev D. / Bhangu A. / Glasbey J.C. / Li E. / Omar O.M. / Simoes J.F. / Abbott T.E. / Alser O. / Arnaud A.P. / Bankhead-Kendall B.K. / Breen K.A. / Cunha M.F. / Davidson G.H. / Di Saverio S. / Gallo G. / Griffiths E.A. / Gujjuri R.R. / Hutchinson P.J. / Kaafarani H.M. /
    Lederhuber H. / Loffler M.W. / Mashbari H.N. / Minaya-Bravo A. / Morton D.G. / Moszkowicz D. / Pata F. / Tsoulfas G. / Venn M.L. / Cox D. / Roslani A.C. / Alakaloko F. / de Vries J.-P.P. / Aaraj M.A. / Abbott S.J. / Abdalla M.O. / Abdelaal A.S. / Ademuyiwa A.O. / Aherne T.M. / Ali O.M. / Alkadeeki G.Z. / Almeida A.C. / Alrahawy M.M. / Ambler G.K. / Alameer E. / Andreani S.M. / De Andres-Asenjo B. / Antonanzas L.L. / Aoun S.G. / Ashoush F.M. / Augestad K.M. / Avellana R.B. / Ayeni F.A. / Ayorinde J.O. / Babu B.H. / Baig M.M. / Bajomo O.M. / Baker O.J. / Baker M.P. / Baldwin A.J. / Ban V.S. / Baron R.D. / Barranquero A.G. / Barry C.P. / DI Bartolomeo A. / Bass G.A. / Bath M.F. / Batjer H.H. / Beamish A.J. / Belgaumkar A.P. / Bence M.N. / Benson R.A. / Bernal-Sprekelsen J.C. / Bhama A.R. / Bhavaraju A.V. / Biffl W.L. / Blundell C.M. / Boddy A.P. / Borgstein A.B. / Bosanquet D.C. / Bosch K.D. / Bouhuwaish A.E. / Bozkurt M.A. / Brathwaite C.E. / Brown B.C. / Brown O.D. / Brown A.K. / Buarque I.L. / Bueno-Canones A.D. / Bulugma M.R. / Burke J.R. / Byrne M.H. / Cagigal-Ortega E.P. / Callcut R.A. / DI Candido F. / Canova M.E. / Carlos W.J. / Caruana E.J. / Cato L.D. / Catton A.B. / Ceretti A.P. / Chase T.J. / Chiara F.D. / Chowdhury A.H. / Chung E.A. / Cicerchia P.M. / Clough E.C. / Coleman N.L. / Collins C.G. / Collins M.L. / Colonna E.T. / Comini L.V. / Coughlin P.A. / Cruzado L.F.-G. / Davidson B.R. / Davies R.J. / Davies E.J. / Davis N.F. / Dawson B.E. / Dean B.J. / Delgado M.G.-C. / Diaz J.J. / Dickson K.E. / Diez-Alonso M.M. / Dixon J.R. / Doe M.J. / Drake T.D. / Drake F.T. / Duffy J.P. / Dunne D.F. / Dunne N.J. / Duran-Munoz-Cruzado V.M. / Durst A.Z. / Eardley N.J. / Edwards J.G. / Elfallal A.H. / Elfiky M.M. / Elliott J.A. / Emile S.H. / Emslie K.M. / Endorf F.W. / Engel J.L. / Enjuto D.T. / Etchill E.W. / Evans J.P. / Fahey B.A. / Faria C.S. / Feo C.V. / Ferguson H.J. / Fernandez B.D. / Fernandez A.G. / Fernandez A.J. / Fernandez-Pacheco B.C. / Fitzgerald J.E. / Fonsi G.B. / Font R.F. / Fowler A.L. / Fretwell K.R. / Fructuoso L.S. / Fusai G.K. / Garcia M.H. / Garcia-Urena M.A. / Gill C.K. / Gisbertz S.S. / Del Giudice R. / Giuffrida M.C. / Di Giuseppe M. / Gomez M.F. / Guariglia C.A. / Hainsworth A.J. / Hall B.J. / Hall J.R. / Hammond J.S. / Haqqani M.H. / Harrison E.M. / Hazelton J.P. / van Heinsbergen M. / Hill A.D. / Hing C.B. / Hirji S.A. / Ho M.W. / Holbrook C.M. / Holme T.J. / Hopkins J.C. / Hopkinson D.N. / Hossain F.S. / Hudson V.E. / Hughes J.L. / Hwang E.S. / Ibrahim M.A. / Isolani S.M. / Jenkinson M.D. / Jenny H.E. / Jeyaretna D.S. / Jones R.P. / Jones A.P. / Jonker P.K. / Jonsson M.L. / Joyce D.P. / Kalkwarf K.J. / Kamarajah S.K. / El Kassas M. / Kavanagh D.O. / Keatley J.M. / Khalefa M.A. / Khan J.S. / Kirmani B.H. / Kisiel A.P. / Kouris S.M. / Kowal M.R. / Labib P.L. / Larkin J.O. / Lauscher J.C. / Leclercq W.K. / Ledesma F.S. / Leite-Moreira A.M. / Leung E.Y. / Lewis S.E. / Lima M.J. / Lin D.J. / Liu H.H. / Lowery A.J. / Lozano S.M. / Luney C.R. / Maia M.M. / Mariani N.M. / Marino M.V. / Marra A.A. / Marsh C.L. / Martin R.C. / McCluney S.J. / McIntyre R.C. / Mckay S.C. / McKevitt K.L. / Meagher A.D. / Mehdi M.Q. / Mehigan B.J. / Gonzalez-De Miguel M. / De Miguel-Ardevines M.-C. / Mills S.J. / Mohan H.M. / Moir J.A. / Monson J.R. / Monteiro J.M. / Montella M.T. / Montesinos C.S. / Morgom M.M. / Moura F.S. / Muguerza J.M. / Murphy S.H. / De Nardi P. / Naumann D.N. / Neary P.C. / Neely D.T. / Ng-Kamstra J.S. / Ngu A.W. / Nguyen T.A. / Nita G.E. / Nunes Q.M. / Nygaard R.M. / O'Meara L.B. / O'Neill J.R. / Okafor B.U. / Olson S.A. / Oo A.Y. / Ormazabal P.C. / Osorio A.L. / Pachl M.J. / Parry J.T. / Patel P.K. / Perez-Sanchez L.E. / Pevidal A.N. / Pezzuto A.P. / Philp M.M. / Pinkney T.D. / Pollok J.M. / Povey M.G. / Poza A.A. / Rajgor A.D. / Rao J.N. / Raptis D.A. / Rice H.E. / Ridgway P.F. / Rivas A.M. / Rodriguez-Sanjuan J.C. / Rogers L.J. / Da Roit A. / Rollett R.A. / Romera J.L. / Rooney S.M. / Roxo V.I. / Le Roy B. / Rubio E.E. / Ruiz C.C. / Ruiz M.L. / Ryan E.J. / Saad A.R. / Saeed S.A. / Salama H.A. / Salamah A.A. / Sampietro G.M. / Sarma D.R. / Schaffer K.B. / Schnitzbauer A.A. / Scurrah R.J. / Serevina O.L. / Serralheiro P.A. / Sewards J.M. / Shackcloth M.J. / Shaw A.V. / Sheel A.R. / Sica G.S. / De Simone V. / Singh A.A. / Singh R.P. / Skelly B.L. / Smith H.G. / Sohail A.H. / Spalding D.R. / Springford L.R. / Ssentongo A.E. / Steinkamp P.J. / Stevens K.A. / Stewart G.D. / Stylianides N.A. / Sullivan T.B. / Taher A.S. / Tamimy M.S. / Tang A.M. / Tebala G.D. / Tejero-Pintor F.J. / Thaha M.A. / Thomas A.J. / De Toma G. / La Torre F. / Torres A.J. / Townshend D.N. / Trout I.M. / Tucker S.C. / Ubhi H.K. / Vega V.A. / Velmahos G.C. / Velopulos C.G. / Viswanath Y.K. / Vivas A.A. / Wade R.G. / Wadley M.S. / Wall J.J. / Walters A.M. / Warren O.J. / Weerasinghe C.K. / Wilkin R.J. / Williams K.J. / Winter S.C. / Wormald J.C. / Wright F.L. / Xyda S.E. / Young A.L. / Youssef M.M. / Yousuf F.B. / El Youzouri H. / Zappa M.A. / Abate E. / Abdalaziz H. / Abdelkarim M. / Abdou H. / Aboelkassem-Ibrahim A. / Abuown A. / Acebes-Garcia F. / Acharya M. / Adamina M. / Addae-Boateng E. / Aftab R. / Agarwal A. / Aguilar J. / Ahmed Y. / Aitken E. / Al-Azzawi M. / Al-Embideen S. / Al-Masri M. / Al-Najjar H. / Al-Sukaini A. / Alam R. / Alderson D. / Aliyeva Z. / Aljanadi F. / Almasri M. / Alonso-Ortuno P. / Altintoprak F. / Amira G. / Amjad R. / Anania G. / Andabaka T. / Angelou D. / Annamalai S. / Annessi V. / Anthoney J. / Anwar S. / Anwer M. / Aragon-Chamizo J. / Ardito A. / Arigoni M. / Armao T. / Arminio A. / Armstrong L. / Arnaud A. / Asaad P. / Ashcroft J. / Ashmore C. / Asqalan A. / Asti E. / Aubry E. / Aytac E. / Ayuso-Herrera E. / Baeza M. / Bailon-Cuadrado M. / Bakmaz B. / Baldi C. / Baldini E. / Baldo S. / Ballabio M. / Baloyiannis I. / Baltazar G. / Bambina F. / Bandiera A. / Barlow E. / Barmasse R. / Barmpagianni C. / Baronio G. / Barra F. / Bartsch A.-M. / Basgaran A. / Basha A. / Bashkirova V. / Bastazza M. / Baumber R. / Belcher E. / Belvedere A. / Benitez-Linero I. / Bergeat D. / Bernasconi M. / Bhalla A. / Bhutiani N. / Bianco F. / Bisagni P. / Blake I. / Blanco-Colino R. / Blazquez-Martin A. / Boal M. / Bonavina L. / Bonavina G. / Bond-Smith G. / Booth K. / Borges F. / Borghi F. / Bouchagier K. / Bourke G. / Boyle E. / Brachini G. / Brain J. / Brar A. / Breckles L. / Bretagnol F. / Brixton G. / Bruzzaniti P. / Bueser T. / Burnside N. / Caballero A. / Calcerrada-Alises E. / Callahan M. / Camarero E. / Campagnaro T. / Campanelli M. / Candiani M. / Cantalejo-Diaz M. / Cao H. / Capelli P. / Capizzi V. / Carcano G. / Carissimi F. / Carlini M. / Carlucci M. / Carmichael H. / Carrasco M. / Carrillo M. / Carvello M. / Casati M. / Castoro C. / Catalan V. / Cavaleiro S. / Cellerino P. / Centinaio G. / Cernei C. / Cerro C. / Cervellera M. / Chakrabortee S. / Chamberlain S. / Chan J. / Chang G. / Chaudhry D. / Chebaro A. / Chen D. / Chetty G. / Chia Z. / Chiappini A. / Chiarugi M. / Chidambaram S. / Chiozza M. / Cholewa H. / Chong C. / Choolani-Bhojwani E. / Christoforidis D. / Chui K. / Chung C. / Cirillo B. / Citterio D. / Clermidi P. / Coccolini F. / Colletti G. / Compagnoni B. / Concepcion-Martin V. / Confalonieri M. / Connolly H. / Conso C. / Conti L. / Cooper Z. / Cordera F. / Corral J. / Costa M. / Costanzi A. / Cotsoglou C. / Cozza V. / Cuming T. / Curtis M. / Cuschieri J. / D'Agruma M. / D'Andrea G. / Daliya P. / Dare O. / Darko E. / Day A. / Dehal A. / Dehart D. / Delgado-Oliver E. / Denning M. / Desai A. / Desender L. / Dester S. / Diaz-Garcia A. / Diaz-Pena P. / Dousset B. / Doussot A. / Duchateau N. / Duff S. / Dunning J. / Duque-Mallen V. / Dziakova J. / Egan B. / Egan R. / El-Ali A. / Elfeki H. / Elhadi M. / Eljareh M. / Elkady R. / Elkhafeefi F. / Elmore U. / Elmoslemany T. / Emmerson O. / Enemosah I. / English C. / English W. / Escartin J. / Estaire-Gomez M. / Evans L. / Evans J. / Exley R. / Fabbri N. / Falco G. / Familiari P. / Fancellu A. / Farik S. / Farrell T. / Fehervari M. / Fell A. / Fernandez-Camunas A. / Fernandez-Marin R. / Fernandez-Martinez M. / Ferrara F. / Ferrari G. / Ferrero S. / Findlay L. / Fiore M. / Fiori E. / Flatman M. / Flindall I. / Flor B. / Fontana T. / Ford S. / Ford D. / Forlani S. / Francone E. / Frattaruolo C. / Frio F. / Gagliano A. / Gagliardi F. / Gahunia S. / Gaino F. / Gala T. / Galfrascoli E. / Galimberti L. / Gallagher P. / Galleano R. / Galvan-Perez A. / Gammeri E. / Ganau M. / Garces-Garcia R. / Garulli G. / Gascon-Ferrer I. / Gattolin A. / Gaujoux S. / Gentilli S. / Georgiades F. / Ghanbari A. / Ghosh D. / Giacometti M. / Giblin A.-V. / Gilbert C. / Gimenez C. / Giorgakis E. / Gipponi M. / Glen P. / Goatly G. / Gobatti D. / Godbole C. / Gohil K. / Gomez M. / Gomez-Rosado J.-C. / Gonullu E. / Gonzalez-Gonzalez E. / Gordini L. / Gracia I. / Gracia-Roche C. / Granieri S. / Green S. / Grivon M. / Grove T. / Guaglio M. / Guaitoli E. / Guglielmi A. / Guha S. / Gustavino C. / Habeeb A. / Hagger R. / Hakmi H. / Halkias C. / Hall C. / Hampton M. / Handa S. / Hansen L. / Haq I. / Harky A. / Harries R. / Harrison J. / Hasan R. / Hawari M. / Hawkin P. / Hebblethwaite B. / Henriques S. / Heritage E. / Hernandez-Juara P. / Herrero-Lopez M. / Hervieux E. / Heyd B. / Higgs S. / Hitchman L. / Ho B. / Hogan A. / Holzle F. / Hossain T. / Hurt L. / Hutchinson P. / Iacob G. / Iannone I. / Ibrahim S. / Iovino D. / Isik A. / Jafarova S. / Jamil T. / Jayaraju U. / Jenner E. / Jimenez-Higuera E. / Jimeno J. / Jones M. / Judkins N. / Kalavrezos N. / Kalidindi V. / Kalkat M. / Kamal M. / Kamphues C. / Kang C. / Kara Y. / Karam E. / Karim A. / Kashora F. / Kearney D. / Khajuria A. / Khan U. / Khan A. / Khatri C. / Kinnaman G. / Kinross J. / Kler A. / Klimopoulos S. / Kocatas A. / Kolias A. / Konigsrainer A. / Konsten J. / Kontovounisios C. / Kourdouli A. / Krishnan E. / Kristinsson S. / Kruijff S. / Kudsk-Iversen S. / Kufeji D. / Kugler N. / Kulkarni R. / Kurihara H. / Laface L. / Lakkis Z. / Lami M. / Landaluce-Olavarria A. / Lapolla P. / Lawani I. / Lawday S. / Lazaro A. / Lecolle K. / Leventoglu S. / Li Z. / Liew I. / Lisi G. / Lizzi V. / Lo T. / Lomiento D. / Longhi M. / Lostis E. / Lostoridis E. / Loubani M. / Lowy-Benoliel A. / Lucianetti A. / Luke L. / Lunevicius R. / Luraghi M. / Lye G. / Mabrouk I. / Macchi A. / MacDonald L. / Machairas N. / Madonini M. / Magowan D. / Maisonneuve E. / Majkowska A. / Majkowski L. / Mak J. / Malabarba S. / Malerba M. / Mannan S. / Manson J. / Mansuri A. / Mantoglu B. / Manu N. / Maqsood A. / Marano A. / Marchbank A. / Marcos-Santos P. / Marrano E. / Martin J. / Martin E. / Martin G. / Martin-Albo L. / Martin-Roman L. / Martinelli F. / Martinez-dePaz F. / Martinez-German A. / Martinez-Pinedo C. / Martins R. / Marwan H. / Marzi F. / Mathieu P. / Matute-Najarro M.-S. / Maw A. / Mazingi D. / Mazzaferro V. / McCanny A. / McKenzie K. / McLarty N. / McPherson I. / Medina E. / Mediratta S. / Medone M. / Mehra G. / Mele S. / Melero-Cortes L. / Mendoza-Moreno F. / Meneghini S. / Mercante G. / Merdrignac A. / Merola S. / Metallidis S. / Michel M. / Migliore M. / Mihanovic J. / Miller D. / Mingoli A. / Minto G. / Mirabella A. / Misra N. / Mitrasinovic S. / Miu V. / Moawad N. / Mochet S. / Modabber A. / Mohammad A. / Mohan M. / Moliner-Sanchez C. / Mongelli F. / Monteleone M. / Montuori M. / Moore R. / Mora-Guzman I. / Morales X. / Morales D. / Morelli L. / Morgan R. / Morris C. / Mortini P. / Mosca A. / Motter D. / Moug S. / Mukherjee S. / Najdy M. / Nakas A. / Namazov I. / Naredla P. / Nasef E. / Nassa H. / Nath R. / Navarro-Sanchez A. / Nazarian S. / Negri G. / Nehra D. / Neil-Dwyer J. / Neri J. / Newton K. / Nikaj H. / Niquen M. / Nobile S. / Nogueiro J. / Ntirenganya F. / Nugent M. / Nunez J. / Ocana J. / Okechukwu V. / Oliva-Mompean F. / Oliveira A. / Ollat D. / Onos L. / Osagie-Clouard L. / Osman K. / Ottolina J. / Ourieff J. / Outani O. / Oyewole B. / Ozben V. / Pacheco-Sanchez D. / Padilla-Valverde D. / Pai M. / Paiella S. / Paisley S. / Palini G. / Palmeri M. / Panahi P. / Parente A. / Parlanti D. / Parmar C. / Pascual A. / Patel M. / Pathak A. / Patil S. / Pattyn P. / Peckham-Cooper A. / Pedrazzani C. / Pellino G. / Peluso C. / Pereira A. / Pereira-Neves A. / Perez-Diaz M.D. / Perez-Gonzalez M. / Perez-Saborido B. / Perivoliotis K. / Perkins C. / Peros G. / Perotto O. / Perra T. / Petrone P. / Phenix G. / Picazo S. / Picon-Rodriguez R. / Piloni M. / Pingarron-Martin L. / Pinotti E. / Pisanu A. / Pizzini P. / Pockney P. / Podda M. / Podolsky D. / Poggioli G. / Pompili C. / Pontari M. / Porcu A. / Potter R. / Price C. / Pruvot F.-R. / Pujol-Muncunill R. / Puppo A. / Quante M. / Quintana-Villamandos B. / Qureshi A. / Radenkovic D. / Rakvin I. / Ramallo-Solis I. / Ramcharan S. / Ramos D. / Ramos-Bonilla A. / Ramzi J. / Rathinam S. / Rausa E. / Ravaioli M. / Ravindran S. / Raymond T. / Razik A. / Redfern J. / Reguera-Rosal J. / Rela M. / Rey-Biel J. / Rey-Valcarcel C. / Ribolla M. / Richards T. / Richmond M. / Righini E. / Rio-Gomez J. / Riyat H. / Rizvi S. / Roberts K. / Roberts M. / Robertson S. / Robertson R. / Robin-Valle A. / Rochon M. / Rojo M. / Rolli L. / Romano S. / Ross E. / Ross H. / Rossborough C. / Rottoli M. / Ruiz-Grande F. / Ruiz-Martin I. / Ruiz-Soriano M. / Ruzzenente A. / Ryska O. / Saez C. / Sagnotta A. / Sahnan K. / Sahni A. / Salim A. / Sallam I. / Salvia R. / Samadov E. / Sammarco G. / Sampaio-Alves M. / Sanchez-Arteaga A. / Sanchez-Fuentes M.-N. / Sanchez-Pelaez D. / Sanchez-Perez C. / Sanchez-Rubio M. / Sancho-Muriel J. / Sanders J. / Santero-Ramirez M.-P. / Santora T. / Santoro A. / Santos I. / Santos-Sousa H. / Sapienza P. / Sartarelli L. / Sarveswaran J. / Sasia D. / Saudemont A. / Saudi-Moro S. / Saxena S. / Saxena D. / Sayasneh A. / Scalabre A. / Schache A. / Schiavina R. / Schineis C. / Schreckenbach T. / Scorza A. / Scott L. / Seegert S. / Seguin-Givelet A. / Senent-Boza A. / Seymour K. / Shabana A. / Shah K. / Shah J. / Shah P. / Shah S. / Shakir T. / Shalaby M. / Shankar S. / Shaw R. / Shehata S. / Shenfine A. / Sheridan K. / Sherief A. / Sherief M. / Sherif M. / Shinkwin M. / Shu S. / Siaw-Acheampong K. / Sileri P. / Singh A. / Singh S. / Sinha S. / Sinha D. / Siragusa L. / Sivaprakasam R. / Sivayoganathan S. / Smillie R. / Smith C. / Smith A. / Sochorova D. / Soggiu F. / Sohrabi C. / Solari F. / Solli P. / Soreide K. / Spinelli A. / Spoletini D. / Spriano G. / Sravanam S. / Ssentongo P. / Stanger S. / Stavroulias D. / Steel B. / Stella M. / Stewart R. / Stringer S. / Sulen N. / Sundar S. / Sundhu M. / Suri A. / Syed A. / Szatmary P. / Tabiri S. / Tadross D. / Taglietti L. / Tansey R. / Tartaglia D. / Tawheed A. / Tayeh S. / Teles T. / Testa V. / Tewari N. / Thoenissen P. / Thomas K. / Thomin A. / Thrush J. / Tierney S. / Tiwari A. / Toh S. / Toledo E. / Tonini V. / Torkington J. / Torquati A. / Torzilli G. / Totty J. / Tourountzi P. / Tousidonis M. / Townend P. / Townsend C. / 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G.S. / Mateo-Sierra O. / Martinez-Perez C. / Serrano Gonzalez J. / Hernandez Bartolome M.A. / Diaz Perez D. / Gutierrez Samaniego M. / Galindo Jara P. / Sharma N. / Smart N.J. / Keller D.S.

    an international cohort study

    2020  

    Abstract: Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and ... ...

    Abstract Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods: This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings: This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 81·7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28–2·40], p<0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65–3·22], p<0·0001), American Society of Anesthesiologists grades 3–5 versus grades 1–2 (2·35 [1·57–3·53], p<0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01–2·39], p=0·046), emergency versus elective surgery (1·67 [1·06–2·63], p=0·026), and major versus minor surgery (1·52 [1·01–2·31], p=0·047). Interpretation: Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. Funding: National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research.
    Keywords Adult ; Aged ; Betacoronavirus ; Coronavirus Infections ; Elective Surgical Procedures ; Emergency Medical Services ; Female ; Hospital Mortality ; Humans ; Male ; Middle Aged ; Pandemics ; Pneumonia ; Viral ; Postoperative Complications ; Respiratory Tract Diseases ; Retrospective Studies ; Surgical Procedures ; Operative ; Young Adult ; covid19
    Subject code 610 ; 616
    Language English
    Publishing country it
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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