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  1. Book ; Online ; E-Book: Gender differences in the pathogenesis and management of heart disease

    Mehta, Jawahar L. / McSweeney, Jean

    2018  

    Author's details Jawahar L. Mehta, Jean McSweeney editors
    Keywords Medicine ; Cardiology
    Subject code 616.12
    Language English
    Size 1 Online-Ressource (xii, 361 Seiten), Illustrationen
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019775312
    ISBN 978-3-319-71135-5 ; 9783319711348 ; 3-319-71135-0 ; 3319711342
    DOI 10.1007/978-3-319-71135-5
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Percutaneous Patent Foramen Ovale Closure: Stroke and Beyond.

    Randhawa, Sandeep / Mehta, Jawahar L / Dhar, Gaurav

    Current cardiology reviews

    2024  

    Abstract: Over 750,000 individuals suffer from stroke annually in the United States, with 87% of these strokes being ischemic in nature. Roughly 40% of ischemic strokes occur in individuals 60 years of age or under. A quarter of all ischemic strokes have no ... ...

    Abstract Over 750,000 individuals suffer from stroke annually in the United States, with 87% of these strokes being ischemic in nature. Roughly 40% of ischemic strokes occur in individuals 60 years of age or under. A quarter of all ischemic strokes have no identifiable cause despite extensive workup and are deemed cryptogenic in nature. Patent Foramen Ovales (PFO) has been postulated in stroke causation by either paradoxical embolization or platelet activation in the tunnel of the defect. The incidence of PFO is reported to be 15-25% in the general population but rises to 40% in patients with cryptogenic stroke. While the initial trials evaluating PFO closures were non-revealing, subsequent long-term follow-ups, as well as recent trials evaluating PFO closures in cryptogenic stroke patients 60 years of age or under, demonstrated the superiority of percutaneous closure compared to medical therapy alone, leading to FDA approval of PFO closure devices. In this review, we review the diagnosis of PFO, postulated stroke mechanisms, literature supporting PFO closure, patient selection for percutaneous closure, procedural considerations, and associated procedural complications.
    Language English
    Publishing date 2024-03-11
    Publishing country United Arab Emirates
    Document type Journal Article
    ISSN 1875-6557
    ISSN (online) 1875-6557
    DOI 10.2174/011573403X276984240304044109
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book ; Online ; E-Book: Biochemical basis and therapeutic implications of angiogenesis

    Mehta, Jawahar L. / Mathur, Pankaj / Dhalla, Naranjan S.

    (Advances in biochemistry in health and disease ; 6)

    2017  

    Author's details Jawahar L. Mehta, Pankaj Mathur, Naranjan S. Dhalla editors
    Series title Advances in biochemistry in health and disease ; 6
    Collection
    Keywords Medicine ; Cancer research ; Human physiology ; Molecular biology ; Cardiology ; Proteins ; Stem cells
    Subject code 612
    Language English
    Size 1 Online-Ressource (viii, 548 Seiten), Illustrationen
    Edition Second edition
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019441209
    ISBN 978-3-319-61115-0 ; 9783319611143 ; 3-319-61115-1 ; 3319611143
    DOI 10.1007/978-3-319-61115-0
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article ; Online: Suicide, Depression, and Cardiovascular Disease.

    Mehta, Jawahar L

    JACC. Heart failure

    2020  Volume 8, Issue 6, Page(s) 519

    MeSH term(s) Cardiovascular Diseases ; Depression ; Heart Failure ; Humans ; Risk Factors ; Suicide
    Language English
    Publishing date 2020-05-25
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2705621-1
    ISSN 2213-1787 ; 2213-1779
    ISSN (online) 2213-1787
    ISSN 2213-1779
    DOI 10.1016/j.jchf.2020.03.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book: Statins

    Mehta, Jawahar L.

    understanding clinical use

    2004  

    Author's details Jawahar L. Mehta
    Keywords Hypercholesterolemia / drug therapy ; Anticholesteremic Agents / therapeutic use ; Statine
    Subject HMG-COA-Reduktasehemmer ; Hydroxymethylglutaryl-COA-Reductase-Hemmer ; Cholesterol-Synthese-Enzym-Hemmer ; CSE-Hemmer ; Statin-Typ-Blutlipidsenker ; Statin type hypolipidaemics
    Language English
    Size XVII, 334 S. : Ill., graph. Darst.
    Publisher Saunders
    Publishing place Philadelphia, Pa
    Publishing country United States
    Document type Book
    HBZ-ID HT014158947
    ISBN 0-7216-0380-7 ; 978-0-7216-0380-3
    Database Catalogue ZB MED Medicine, Health

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  6. Article ; Online: Spirituality and Outcome in Chronic Diseases.

    Mehta, Jawahar L / Mehta, Paulette

    JACC. Heart failure

    2022  Volume 10, Issue 7, Page(s) 528–529

    MeSH term(s) Chronic Disease ; Heart Failure ; Humans ; Spirituality ; Surveys and Questionnaires
    Language English
    Publishing date 2022-05-04
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2705621-1
    ISSN 2213-1787 ; 2213-1779
    ISSN (online) 2213-1787
    ISSN 2213-1779
    DOI 10.1016/j.jchf.2022.04.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Best time for administration of antihypertensive medications: morning or evening?

    Salah, Husam M / Mehta, Jawahar L

    Lancet (London, England)

    2022  Volume 400, Issue 10361, Page(s) 1383–1385

    MeSH term(s) Humans ; Antihypertensive Agents/therapeutic use ; Hypertension/drug therapy ; Blood Pressure Monitoring, Ambulatory ; Circadian Rhythm ; Blood Pressure
    Chemical Substances Antihypertensive Agents
    Language English
    Publishing date 2022-10-11
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(22)01900-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Response to 'Late repercussions of assisted reproductive technology'.

    Mehta, Jawahar L

    European heart journal

    2019  Volume 40, Issue 44, Page(s) 3656

    MeSH term(s) Adult ; Cardiovascular Diseases ; Female ; Humans ; Infant, Newborn ; Pregnancy ; Premature Birth ; Reproductive Techniques, Assisted
    Language English
    Publishing date 2019-12-04
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehz609
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Prior Statin vs In-Hospital Statin Usage in Severe COVID-19: Review and Meta-Analysis.

    Alhallak, Iad / Paydak, Hakan / Mehta, Jawahar L

    Current problems in cardiology

    2023  Volume 48, Issue 9, Page(s) 101810

    Abstract: Studies have shown that statins can decrease COVID-19 mortality in hospitalized patients. This paper evaluates these studies and reviews the possible mechanism of how statins modulate COVID-19 severity. Meta-analysis of 31 retrospective studies ... ...

    Abstract Studies have shown that statins can decrease COVID-19 mortality in hospitalized patients. This paper evaluates these studies and reviews the possible mechanism of how statins modulate COVID-19 severity. Meta-analysis of 31 retrospective studies demonstrated a reduction in mortality rate among statin users (OR 0.69, 95% CI 0.56-0.86, P = 0.0008) (HR 0.83, 95% CI 0.72-0.95, P = 0.0078). Meta-analysis of 8 randomized control studies demonstrated a nonsignificant reduction in mortality (OR 0.90, 95% CI 0.69-1.18, P = 0.461), including 4 studies with medications other than statins, and 4 studies with only statins (OR 0.88, 95% CI 95% CI 0.64-1.21, P = 0.423). Prolonged statin usage decreases the extracellular localization of ACE2, along with statins' immunomodulating effects and reduction of oxidative stress, decreases COVID-19 mortality. Hospitalized patients with COVID-19 should continue statin treatment if previously prescribed, and patients should not be started on statins, as they do not seem to provide any mortality benefit.
    MeSH term(s) Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/therapeutic use ; Retrospective Studies ; COVID-19 ; Hospitals
    Chemical Substances Hydroxymethylglutaryl-CoA Reductase Inhibitors
    Language English
    Publishing date 2023-05-19
    Publishing country Netherlands
    Document type Meta-Analysis ; Journal Article ; Review
    ZDB-ID 441230-8
    ISSN 1535-6280 ; 0146-2806
    ISSN (online) 1535-6280
    ISSN 0146-2806
    DOI 10.1016/j.cpcardiol.2023.101810
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Meta-analysis of the Effect of Colchicine on Mortality and Mechanical Ventilation in COVID-19.

    Salah, Husam M / Mehta, Jawahar L

    The American journal of cardiology

    2021  Volume 145, Page(s) 170–172

    MeSH term(s) COVID-19/mortality ; COVID-19/therapy ; Colchicine/therapeutic use ; Global Health ; Gout Suppressants/therapeutic use ; Humans ; Pandemics ; Respiration, Artificial/methods ; SARS-CoV-2 ; Survival Rate/trends
    Chemical Substances Gout Suppressants ; Colchicine (SML2Y3J35T)
    Language English
    Publishing date 2021-02-19
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Review
    ZDB-ID 80014-4
    ISSN 1879-1913 ; 0002-9149
    ISSN (online) 1879-1913
    ISSN 0002-9149
    DOI 10.1016/j.amjcard.2021.02.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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