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  1. AU="Mehta, Kedar"
  2. AU="Nelly A. Khachatryan"
  3. AU=Albensi Benedict C.
  4. AU=McRae Simon
  5. AU="Shorubalko, Ivan"
  6. AU="Stewart, Rodney A"
  7. AU="Bakthavatsalu, Maheshwar"
  8. AU="Fussner, Steven"
  9. AU="Dolsten, Mikael"
  10. AU="Sarnyai, Zoltán"
  11. AU=Dongaonkar Ranjeet M
  12. AU="Singh, Leher"
  13. AU="Sevilla Porras, Marta"
  14. AU="Fuller, Chris K"
  15. AU="Vandeloo, Judith"
  16. AU="Meyers, Amanda"
  17. AU="Jiménez-Bambague, Eliana M"
  18. AU="Turner, J C"
  19. AU="Moore, C J" AU="Moore, C J"
  20. AU="Leresche, Téa"
  21. AU=Astrom Siv AU=Astrom Siv
  22. AU="Di Meglio, Florent"
  23. AU=Simon H U
  24. AU=Croucher P I
  25. AU="Jasti, Madhu"

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  1. Artikel ; Online: Prevalence of risk factors and estimation of 10-year risk for cardiovascular diseases among male adult population of Tamil Nadu India-an insight from the National Family Health Survey-5.

    Sasikumar, Midhun / Marconi, Sam David / Dharmaraj, Aravind / Mehta, Kedar / Das, Milan / Goel, Sonu

    Indian heart journal

    2023  Band 75, Heft 4, Seite(n) 251–257

    Abstract: Objective: Cardiovascular diseases (CVD) are one of the most addressed preventable diseases of public health importance. However, the risk estimates and use of these risk scores for CVD prevention are the least explored areas. So, in this study, we ... ...

    Abstract Objective: Cardiovascular diseases (CVD) are one of the most addressed preventable diseases of public health importance. However, the risk estimates and use of these risk scores for CVD prevention are the least explored areas. So, in this study, we explored the different categories of Framingham heart study (FHS) 10-year-CVD risk score and their associated factors among the adult male population in Tamil Nadu, India.
    Methods: We used the risk factor level data for male adults aged 18 years and above from the National Family Health Survey (NFHS-5) of Tamil Nadu state, India. Sociodemographic variables, behavioral factors, and physiological/biochemical factors were considered as the risk factor and were estimated using the world health organization (WHO) STEPS categories. FHS 10-year-CVD risk score was calculated using a body-mass index-based published Cox regression equation.
    Results: Out of 2289 adult males, only 1.12% of the participants had a 10-year CVD risk score greater than 30% and ∼4% of the total participants require statin treatment (FRS-CVD risk score ≥20). Educational status (aOR:14.21, 95 CI: 4.36-46.22- no formal schooling when compared to 10th and above standard), weekly fruit intake (aOR:0.51, 95 CI: 0.27-0.97 when compared to daily fruit intake) and abdominal obesity (aOR:2.43, 95 CI: 1.58-3.74) were found to be associated with higher FRS scores when adjusted for all other factors not involved in FRS calculation.
    Conclusion: Widespread use of this score needs to be encouraged in clinical practices and patients with a higher risk of CVD events should be counselled for lifestyle modifications and compliance with treatment for decreasing the burden due to CVDs.
    Mesh-Begriff(e) Adult ; Humans ; Male ; Cardiovascular Diseases/epidemiology ; India/epidemiology ; Prevalence ; Risk Factors ; Health Surveys
    Sprache Englisch
    Erscheinungsdatum 2023-06-17
    Erscheinungsland India
    Dokumenttyp Journal Article
    ZDB-ID 604366-5
    ISSN 2213-3763 ; 0019-4832
    ISSN (online) 2213-3763
    ISSN 0019-4832
    DOI 10.1016/j.ihj.2023.06.003
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: Hypertension and its association with body mass index among the Indian population. Findings from a nationwide survey (NFHS-4), 2015-16.

    Sharma, Shailja / Singh, Harshvardhan / Mehta, Kedar / Verma, Madhur / Goel, Sonu

    Journal of family medicine and primary care

    2022  Band 11, Heft 9, Seite(n) 5826–5833

    Abstract: Background: Globally, hypertension (HTN) and obesity are two cardinal causes of morbidity and mortality. The Asian population shows comorbidities associated with obesity at a much lower body mass index (BMI) than the western population.: Aim: The ... ...

    Abstract Background: Globally, hypertension (HTN) and obesity are two cardinal causes of morbidity and mortality. The Asian population shows comorbidities associated with obesity at a much lower body mass index (BMI) than the western population.
    Aim: The primary objective of the present study was to evaluate the association between BMI and HTN among the adult population.
    Material and methods: We did a cross-sectional secondary data analysis of the NFHS-4 datasets, conducted during 2015-16. We included the adult population, that is, ≥19 years of age (93,040 men and 5,46,066 women), and excluded adolescents and pregnant women from our analysis. HTN was the primary dependent variable, while BMI was the primary predictor variable. Other covariates included age, education, place of residence, wealth index, use of alcohol and tobacco, and diabetes. Weighted analysis was done to depict our results.
    Results: Around 18.7% of men and 13.5% of women were hypertensive, of which 53.86% of males and 38.7% females were either overweight or obese. The odds of living with HTN among obese men and women increased with age, wealth, use of alcohol and tobacco, and comorbidities such as diabetes. The prevalence of HTN was higher even among the underweight adults living with diabetes and those consuming alcohol and tobacco.
    Conclusion: We reaffirm the significant association between BMI and HTN among adults. The use of the Asian classification of BMI for India and its neighboring countries to assess the burden of obesity would help in planning better interventions. A community-based targeted approach would help in controlling and reducing the prevalence of HTN.
    Sprache Englisch
    Erscheinungsdatum 2022-10-14
    Erscheinungsland India
    Dokumenttyp Journal Article
    ZDB-ID 2735275-4
    ISSN 2278-7135 ; 2249-4863
    ISSN (online) 2278-7135
    ISSN 2249-4863
    DOI 10.4103/jfmpc.jfmpc_168_22
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel: In Search for the Optimal Forest Use Behaviour: Riparian Forest Use in Central Asia, Using the Example of Ak-Tal, Naryn, Kyrgyzstan

    Missall, Siegmund / Welp, Martin / Mehta, Kedar / Degembaeva, Nadira / Akmatov, Kuban / Zörner, Wilfried

    Forests. 2022 Aug. 08, v. 13, no. 8

    2022  

    Abstract: Riparian forests are rare and valuable ecosystems in Central Asia, both due to their significance for biodiversity and to their provision of vital ecosystem services to local residents. However, the actual forest use behaviour is under-researched, ... ...

    Abstract Riparian forests are rare and valuable ecosystems in Central Asia, both due to their significance for biodiversity and to their provision of vital ecosystem services to local residents. However, the actual forest use behaviour is under-researched, official figures may not be trustworthy, and the question of over-use is up in the air. This paper sets out to shed light on riparian forest use behaviour by local residents using the example of Ak-Tal Village upon the Naryn River in Kyrgyzstan: Which economic use patterns do they practice (focusing on fuel wood and pasture)? Which other ecosystem services do they recognise? Is there forest over-exploitation? To answer these questions, this study builds on local knowledge, by applying the methods of focus group discussions and a household survey. Results show an extreme discrepancy between official wood consumption figures (50–60 m³ p.a.) and figures based on household wood consumption (310–404 m³ p.a.). The forest also serves as an important winter pasture over the seven months between October and April (stocking density 0.61 livestock units/ha), but payments for these ecosystem services are low, with annually 40 KGS/ha. Local residents are aware of additional material and nonmaterial ecosystem services of the riparian forest. Opinions diverge upon the question if there is forest over-exploitation, potentially because different stakeholders have different concepts of an optimal forest status. Consequently, optimal forest use behaviour can only be defined by the local users themselves, e.g., in a future stakeholder dialogue.
    Schlagwörter air ; biodiversity ; ecosystems ; focus groups ; fuelwood ; household surveys ; livestock ; pastures ; riparian forests ; rivers ; stakeholders ; villages ; Kyrgyzstan
    Sprache Englisch
    Erscheinungsverlauf 2022-0808
    Erscheinungsort Multidisciplinary Digital Publishing Institute
    Dokumenttyp Artikel
    ZDB-ID 2527081-3
    ISSN 1999-4907
    ISSN 1999-4907
    DOI 10.3390/f13081254
    Datenquelle NAL Katalog (AGRICOLA)

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  4. Artikel ; Online: Expanded principles of ethics and its implementation during COVID-19 vaccine trials: A scoping evidence based research synthesis.

    Kumar, Vaibhav / Aranha, Venetia / Rajgarhia, Rajni / Royal, Abhishek / Mehta, Kedar

    Human vaccines & immunotherapeutics

    2021  Band 17, Heft 11, Seite(n) 3843–3849

    Abstract: The COVID-19 pandemic will subside only through the emergence and distribution of an efficacious vaccine. The two main aspects that should be maintained in equilibrium: the dire necessity for speedy vaccine research and the need for safeguarding the ... ...

    Abstract The COVID-19 pandemic will subside only through the emergence and distribution of an efficacious vaccine. The two main aspects that should be maintained in equilibrium: the dire necessity for speedy vaccine research and the need for safeguarding the research subjects, which is of utmost concern in research ethics. This opens up a discussion of what norms to follow during the clinical trials while developing the vaccine. As of now, various companies like Moderna, Pfizer, University of Oxford, Astra-Zeneca and so on have moved beyond the safety, efficacy and immunogenic studies. This narrative review explores and discusses the key principles of ethics: a principle of autonomy, beneficence, non-maleficence, and justice along with its ten general expanded principles. Furthermore, it delves into the different types of vaccines, their mechanisms, side effects, limitations, and advantages.
    Mesh-Begriff(e) COVID-19 ; COVID-19 Vaccines ; Humans ; Pandemics ; SARS-CoV-2
    Chemische Substanzen COVID-19 Vaccines
    Sprache Englisch
    Erscheinungsdatum 2021-07-15
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2664176-8
    ISSN 2164-554X ; 2164-5515
    ISSN (online) 2164-554X
    ISSN 2164-5515
    DOI 10.1080/21645515.2021.1947101
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Efficacy and safety of colchicine in COVID-19: a meta-analysis of randomised controlled trials.

    Mehta, Kedar Gautambhai / Patel, Tejas / Chavda, Paragkumar D / Patel, Parvati

    RMD open

    2021  Band 7, Heft 3

    Abstract: Background: Colchicine, an anti-inflammatory drug is prescribed nowadays for COVID-19. In this meta-analysis, we evaluated efficacy and safety of colchicine in patients with COVID-19.: Methods: We searched databases for randomised controlled studies ... ...

    Abstract Background: Colchicine, an anti-inflammatory drug is prescribed nowadays for COVID-19. In this meta-analysis, we evaluated efficacy and safety of colchicine in patients with COVID-19.
    Methods: We searched databases for randomised controlled studies evaluating efficacy and/or safety of colchicine as compared with supportive care in patients with COVID-19. The efficacy outcomes were mortality, ventilatory support, intensive care unit (ICU) admission and length of hospital stay. The safety outcomes were adverse events, serious adverse events and diarrhoea. A meta-analytical summary was estimated using random effects model through Mantle-Hanzle method. An I
    Results: Out of 69 full texts assessed, 6 studies (16148 patients with COVID-19) were included in meta-analysis. Patients receiving colchicine did not show significant reduction in mortality (risk difference, RD -0.00 (95% CI -0.01 to 0.01), I
    Conclusion: The moderate quality evidence suggests no benefit of addition of colchicine to the standard care regimen in patients with COVID-19.
    Mesh-Begriff(e) COVID-19 ; Colchicine/adverse effects ; Humans ; SARS-CoV-2
    Chemische Substanzen Colchicine (SML2Y3J35T)
    Sprache Englisch
    Erscheinungsdatum 2021-11-22
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 2812592-7
    ISSN 2056-5933 ; 2056-5933
    ISSN (online) 2056-5933
    ISSN 2056-5933
    DOI 10.1136/rmdopen-2021-001746
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel: Screening Vaccinees for Non-Communicable Diseases and Risk Factors at a Covid-19 Vaccination Center in Vadodara, Gujarat.

    Chavda, Paragkumar D / Mehta, Kedar G / Pandya, Chandresh M / Patel, Bharat H / Shah, Paras / Shah, Zalak

    Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine

    2022  Band 47, Heft 3, Seite(n) 400–404

    Abstract: Context: Adult population visiting COVID vaccination center is a potential teachable moment for screening and preventive advice on non-communicable diseases.: Objectives: The objective of this study was to assess the proportion of vaccinees ... ...

    Abstract Context: Adult population visiting COVID vaccination center is a potential teachable moment for screening and preventive advice on non-communicable diseases.
    Objectives: The objective of this study was to assess the proportion of vaccinees volunteering for screening and to know the proportion of newly detected hypertensives and diabetics among the screened vaccinees at COVID-19 vaccination center.
    Setting and design: This descriptive, cross-sectional, operational research study was carried out at the COVID vaccination center at a medical college in central Gujarat from July to September 2021.
    Methods: After receiving the vaccine, the vaccinee was offered screening through a community-based assessment checklist for risk factors of non-communicable diseases, blood pressure, and blood sugar measurement. Those volunteering for this screening received a slip mentioning their risk score, blood pressure and blood sugar reading, and relevant health information and disease prevention advice. The study variables were acceptability (proportion of vaccinees volunteering for screening) and yield (newly detected hypertensives and diabetics among those screened).
    Results: Among vaccinees, 27.7% volunteered for risk scoring and blood pressure measurement, whereas 8.3% volunteered for blood sugar measurement. Around 15.5% of vaccinees had high-risk scores as per the community-based assessment checklist. The yield of freshly detected high blood pressure and high blood sugar was 19.3% and 10.5%, respectively. The yield was similar even among vaccinees under 30 years of age.
    Conclusions: Vaccinees demonstrated interest in undergoing screening for non-communicable diseases. Yield indicates that such screening is worth the effort.
    Sprache Englisch
    Erscheinungsdatum 2022-10-10
    Erscheinungsland India
    Dokumenttyp Journal Article
    ZDB-ID 2085330-0
    ISSN 1998-3581 ; 0970-0218
    ISSN (online) 1998-3581
    ISSN 0970-0218
    DOI 10.4103/ijcm.ijcm_1321_21
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel: Effects of Ultrasound-Guided Lower Extremity Nerve Blocks for Below-Knee Procedures in the Emergency Department of a Tertiary Care Hospital, Central Gujarat.

    Patel, Shreyas K / Parikh, Rina / Gupta, Himanshu / Pancholi, Krunalkumar / Saxena, A K / Chawada, Bansari / Shringarpure, Kalpita S / Mehta, Kedar / Chavda, Parag

    Cureus

    2023  Band 15, Heft 7, Seite(n) e41450

    Abstract: Background and objectives Ultrasound-guided femoral and popliteal sciatic nerve blocks are useful adjuncts for many below-knee procedures like debridement, amputation, etc. The objectives of the study were to find the efficacy and feasibility of the ... ...

    Abstract Background and objectives Ultrasound-guided femoral and popliteal sciatic nerve blocks are useful adjuncts for many below-knee procedures like debridement, amputation, etc. The objectives of the study were to find the efficacy and feasibility of the ultrasound-guided combined femoral and popliteal sciatic nerve block for below-knee procedures in the Emergency Medicine Department (ED). Methodology This prospective clinical study was carried out over three months in ED. A total of 30 patients undergoing below-knee procedures were included in the study. Femoral and popliteal sciatic nerve blocks were administered to each patient using the high-frequency linear ultrasound probe by emergency physicians trained in ultrasound. The effect of blocks, amount of local anesthetic (LA) used, duration of the procedure, and post-block analgesia were recorded. Patients were monitored for possible complications, if any. Data were entered and analyzed using a Microsoft Excel worksheet. Results The average volume of LAs required was around 34.5 cc for both blocks combined. No complications like vascular puncture or nerve injury were reported during the study. The time taken to complete the procedure was around 33 minutes, and the average time to achieve sensory block was around 9 minutes after completing the procedure. Conclusions An ultrasound-guided combined femoral and popliteal sciatic nerve block is an effective and feasible procedure and thus should be considered in ED for below-knee procedures.
    Sprache Englisch
    Erscheinungsdatum 2023-07-06
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.41450
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Outcomes and Challenges in the Programmatic Implementation of Tuberculosis Preventive Therapy among Household Contacts of Pulmonary TB Patients: A Mixed-Methods Study from a Rural District of Karnataka, India.

    Samudyatha, U C / Soundappan, Kathirvel / Ramaswamy, Gomathi / Mehta, Kedar / Kumar, Chandan / Jagadeesh, M / Prasanna Kamath, B T / Singla, Neeta / Thekkur, Pruthu

    Tropical medicine and infectious disease

    2023  Band 8, Heft 12

    Abstract: The National TB Elimination Programme (NTEP) of India is implementing tuberculosis preventive treatment (TPT) for all household contacts (HHCs) of pulmonary tuberculosis patients (index patients) aged ... 5 years with TB ... ...

    Abstract The National TB Elimination Programme (NTEP) of India is implementing tuberculosis preventive treatment (TPT) for all household contacts (HHCs) of pulmonary tuberculosis patients (index patients) aged <5 years and those HHCs aged >5 years with TB infection (TBI). We conducted an explanatory mixed-methods study among index patients registered in the Kolar district, Karnataka during April-December 2022, to assess the TPT cascade and explore the early implementation challenges for TPT provision. Of the 301 index patients, contact tracing home visits were made in 247 (82.1%) instances; a major challenge was index patients' resistance to home visits fearing stigma, especially among those receiving care from the private sector. Of the 838 HHCs, 765 (91.3%) were screened for TB; the challenges included a lack of clarity on HHC definition and the non-availability of HHCs during house visits. Only 400 (57.8%) of the 692 eligible HHCs underwent an IGRA test for TBI; the challenges included a shortage of IGRA testing logistics and the perceived low risk among HHCs. As HHCs were unaware of their IGRA results, a number of HHCs actually eligible for TPT could not be determined. Among the 83 HHCs advised of the TPT, 81 (98%) initiated treatment, of whom 63 (77%) completed treatment. Though TPT initiation and completion rates are appreciable, the NTEP needs to urgently address the challenges in contact identification and IGRA testing.
    Sprache Englisch
    Erscheinungsdatum 2023-11-30
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ISSN 2414-6366
    ISSN (online) 2414-6366
    DOI 10.3390/tropicalmed8120512
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel ; Online: Multidrug-resistant

    Vidal, Juana L / Clavijo, Viviana / Castellanos, Luis R / Kathiresan, Jeyashree / Kumar, Ajay M V / Mehta, Kedar / Chaparro-Gutiérrez, Jenny J

    Revista panamericana de salud publica = Pan American journal of public health

    2023  Band 47, Seite(n) e46

    Abstract: Objectives: To determine the proportion of : Methods: This was a laboratory-based cross-sectional study of routine data on fecal samples received from pig farms in all nine subregions of Antioquia state, Colombia. : Results: Of 653 samples tested, ...

    Abstract Objectives: To determine the proportion of
    Methods: This was a laboratory-based cross-sectional study of routine data on fecal samples received from pig farms in all nine subregions of Antioquia state, Colombia.
    Results: Of 653 samples tested, 149 (23%) were positive for
    Conclusions: The proportion of
    Sprache Englisch
    Erscheinungsdatum 2023-04-19
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 1376934-0
    ISSN 1680-5348 ; 1020-4989
    ISSN (online) 1680-5348
    ISSN 1020-4989
    DOI 10.26633/RPSP.2023.46
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel: Pharmacy based surveillance for identifying missing tuberculosis cases: A mixed methods study from South India.

    Frederick, Asha / Das, Mrinalini / Mehta, Kedar / Kumar, Ganesh / Satyanarayana, Srinath

    The Indian journal of tuberculosis

    2020  Band 68, Heft 1, Seite(n) 51–58

    Abstract: Background: No Indian studies have assessed the implementation of recent policy on pharmacy based surveillance and its contribution in TB notification. So, this study was conducted with objectives to describe: a) pharmacy based TB surveillance and TB ... ...

    Abstract Background: No Indian studies have assessed the implementation of recent policy on pharmacy based surveillance and its contribution in TB notification. So, this study was conducted with objectives to describe: a) pharmacy based TB surveillance and TB notification, and b) experiences of pharmacy based surveillance implementation from the programme managers and pharmacists perspective.
    Methods: A mixed methods study-quantitative (cross-sectional) and qualitative (in-depth interviews) in two selected districts Dharmapuri and Salem districts of Tamil Nadu State, India.
    Results: In 2018, 45 (11%) of 397 pharmacies in Dharmapuri and 90 (6%) of 1457 pharmacies in Salem districts reported sale of anti-TB drugs to 1307 and 1673 persons respectively. Upon validation through direct patient contact 942 (72%) persons in Dharmapuri and 863 (52%) persons were identified as previously 'un-notified' TB patients. These patients constituted 20% and 29% of the total TB cases notified in Dharmapuri and Salem respectively. The enablers for implementing this activity were: understanding the importance of notification, availability of resources (manpower, computers) to record, report and validate the patient data, repeated trainings and partnerships. The barriers were: patients' hesitancy to share their details to pharmacists (confidentiality), cumbersome recording and reporting process, difficulties in recording patient details during high workload busy business hours.
    Conclusion: This process contributed about one-fourth of the TB patients notified in these districts. Its implementation needs to be strengthened and should be scaled up in other parts of the country.
    Mesh-Begriff(e) Antitubercular Agents/economics ; Antitubercular Agents/therapeutic use ; Commerce/statistics & numerical data ; Cross-Sectional Studies ; Humans ; India/epidemiology ; Interviews as Topic ; National Health Programs ; Outcome Assessment, Health Care ; Pharmaceutical Services ; Population Surveillance ; Tuberculosis, Pulmonary/drug therapy ; Tuberculosis, Pulmonary/epidemiology
    Chemische Substanzen Antitubercular Agents
    Sprache Englisch
    Erscheinungsdatum 2020-09-25
    Erscheinungsland India
    Dokumenttyp Journal Article
    ZDB-ID 603129-8
    ISSN 0019-5707 ; 0019-5705
    ISSN 0019-5707 ; 0019-5705
    DOI 10.1016/j.ijtb.2020.09.017
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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