Artikel ; Online: The effect of mother's age on the neonatal cord serum's oxidative stress index and maternal and neonatal outcomes: a case control study.
2024 Band 24, Heft 1, Seite(n) 61
Abstract: Background: One of the main challenges of many societies in reducing and ageing of the population is marriage at an advanced age in women and decrease of producing offspring due to the concern of increasing the probability of maternal and neonatal ... ...
| Abstract | Background: One of the main challenges of many societies in reducing and ageing of the population is marriage at an advanced age in women and decrease of producing offspring due to the concern of increasing the probability of maternal and neonatal outcomes. The mother's oxidative stress conditions during pregnancy affect mothers and their baby's health. Aging is one of the increasing factors of oxidants in the body. Aim of this study is the compartion total antioxidant capacity (TAC), total oxidants status (TOS), oxidative stress index (OSI) values, and maternal and neonatal outcomes in three groups of mothers with different age ranges from 20 to 29, 30 to 34, and 35 to 45 years old. Methods: 164 pregnant women were grouped according to age into three groups: 25 to 30 (group I), 30 to 35 (group II), and 35 to 45 years old (group III). The umbilical cord blood samples were taken to the assay TAC, TOS, and OSI (TOS/TAC). The Kolmogorov-Smirnov test was employed to assess the normal distribution of countinus variables. The one-way ANOVA and Kruskal-Wallis test were used to compare anthropometric and biochemical factors between groups. Results: TAC levels decreased non-significantly (438.2 ± 102; 431.7 ± 99.8; and 428.2 ± 100.26 for groups I, II, and III respectively, P value = 0.99), TOS levels increased significantly (23.93 ± 11.7; 25.4 ± 12.3; and 28.2 ± 12.7 for groups I, II, and III respectively, P value = 0.034), and OSI increased non-significantly with increasing maternal age (0.055 ± 0.044; 0.091 ± 0.031; 0.069 ± 0.005, for groups I, II, and III respectively, P value = 0.14). Increasing age did not significantly affects the maternal and infant birth outcomes. Conclution: The results showed that the increasing the age of the mother up to 45 doesn't have a significant effects on the value of OSI and the maternal and infant outcomes. |
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| Mesh-Begriff(e) | Infant, Newborn ; Humans ; Female ; Pregnancy ; Young Adult ; Adult ; Mothers ; Case-Control Studies ; Oxidative Stress ; Antioxidants/metabolism ; Oxidants |
| Chemische Substanzen | Antioxidants ; Oxidants |
| Sprache | Englisch |
| Erscheinungsdatum | 2024-01-12 |
| Erscheinungsland | England |
| Dokumenttyp | Journal Article |
| ZDB-ID | 2059869-5 |
| ISSN | 1471-2393 ; 1471-2393 |
| ISSN (online) | 1471-2393 |
| ISSN | 1471-2393 |
| DOI | 10.1186/s12884-023-06239-4 |
| Datenquelle | MEDical Literature Analysis and Retrieval System OnLINE |
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