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  1. AU="Meier, Dieter"
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  1. Book: Out of Chaos

    Meier, Dieter

    ein autobiografisches Bilderbuch ; [inkl. Das Kapitel Yello]

    2011  

    Author's details Dieter Meier
    Keywords Artists
    Language German
    Size 328 S., überw. Ill.
    Edition 1. Aufl.
    Publisher Edel Germany
    Publishing place Hamburg
    Document type Book
    ISBN 3841901034 ; 9783841901033
    Database Former special subject collection: coastal and deep sea fishing

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  2. Book ; Thesis: Immunselektion von Oligodendrozyten mit magnetischen Kügelchen

    Meier, Dieter H.

    Determination von Parametern zur Antikörperbindung und Bedingungen der Zellbindung ; Kultivation der immunselektionierten Oligodendrozyten

    1982  

    Size Getr. Zählung : Ill.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Heidelberg, Univ., Diss., 1983
    HBZ-ID HT003254292
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    83 E 698 order for loan Magazin

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  3. Book ; Online ; Thesis: Screening for novel antimicrobial agents and elucidation of the corresponding mechanisms

    Meier, Dieter [Verfasser] / Kalscheuer, Rainer [Akademischer Betreuer] / Proksch, Peter [Gutachter]

    2020  

    Author's details Dieter Meier ; Gutachter: Peter Proksch ; Betreuer: Rainer Kalscheuer
    Keywords Biowissenschaften, Biologie ; Life Science, Biology
    Subject code sg570
    Language English
    Publisher Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf
    Publishing place Düsseldorf
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

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  4. Book ; Online: Leitung, Besteuerung und Finanzierung der jugoslawischen Industrieunternehmungen im Vergleich mit deutschen Aktiengesellschaften

    Meier, Dieter

    1968  

    Abstract: PDie Südosteuropa-Studien werden von der in München ansässigen Südosteuropa-Gesellschaft, der wichtigsten Wissenschaftsorganisation der Südosteuropa-Forschung im deutschsprachigen Raum, herausgegeben. Sie dienen der vertieften und interdisziplinären ... ...

    Abstract PDie Südosteuropa-Studien werden von der in München ansässigen Südosteuropa-Gesellschaft, der wichtigsten Wissenschaftsorganisation der Südosteuropa-Forschung im deutschsprachigen Raum, herausgegeben. Sie dienen der vertieften und interdisziplinären wissenschaftlichen Darstellung wichtiger Themen aus der Südosteuropa-Forschung. Auch Fragen zur aktuellen politischen und sozio-ökonomischen Entwicklung in der Region Südosteuropa werden aufgegriffen. Herausgeber der Einzelbände sind renommierte Repräsentanten der deutschen und internationalen Südosteuropa-Forschung./P
    Size 1 electronic resource (116 p.)
    Publisher Peter Lang International Academic Publishing Group
    Document type Book ; Online
    Note German ; Open Access
    HBZ-ID HT020100926
    ISBN 9783631739990 ; 3631739990
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Article ; Online: The genome of Ricinus communis encodes a single glycolate oxidase with different functions in photosynthetic and heterotrophic organs.

    Schmitz, Jessica / Hüdig, Meike / Meier, Dieter / Linka, Nicole / Maurino, Veronica G

    Planta

    2020  Volume 252, Issue 6, Page(s) 100

    Abstract: Main conclusion: The biochemical characterization of glycolate oxidase in Ricinus communis hints to different physiological functions of the enzyme depending on the organ in which it is active. Enzymatic activities of the photorespiratory pathway are ... ...

    Abstract Main conclusion: The biochemical characterization of glycolate oxidase in Ricinus communis hints to different physiological functions of the enzyme depending on the organ in which it is active. Enzymatic activities of the photorespiratory pathway are not restricted to green tissues but are present also in heterotrophic organs. High glycolate oxidase (GOX) activity was detected in the endosperm of Ricinus communis. Phylogenetic analysis of the Ricinus L-2-hydroxy acid oxidase (Rc(L)-2-HAOX) family indicated that Rc(L)-2-HAOX1 to Rc(L)-2-HAOX3 cluster with the group containing streptophyte long-chain 2-hydroxy acid oxidases, whereas Rc(L)-2-HAOX4 clusters with the group containing streptophyte GOX. Rc(L)-2-HAOX4 is the closest relative to the photorespiratory GOX genes of Arabidopsis. We obtained Rc(L)-2-HAOX4 as a recombinant protein and analyze its kinetic properties in comparison to the Arabidopsis photorespiratory GOX. We also analyzed the expression of all Rc(L)-2-HAOXs and conducted metabolite profiling of different Ricinus organs. Phylogenetic analysis indicates that Rc(L)-2-HAOX4 is the only GOX encoded in the Ricinus genome (RcGOX). RcGOX has properties resembling those of the photorespiratory GOX of Arabidopsis. We found that glycolate, the substrate of GOX, is highly abundant in non-green tissues, such as roots, embryo of germinating seeds and dry seeds. We propose that RcGOX fulfills different physiological functions depending on the organ in which it is active. In autotrophic organs it oxidizes glycolate into glyoxylate as part of the photorespiratory pathway. In fast growing heterotrophic organs, it is most probably involved in the production of serine to feed the folate pathway for special demands of those tissues.
    MeSH term(s) Alcohol Oxidoreductases/genetics ; Genome, Plant/genetics ; Photosynthesis/genetics ; Phylogeny ; Ricinus/classification ; Ricinus/enzymology ; Ricinus/genetics
    Chemical Substances Alcohol Oxidoreductases (EC 1.1.-) ; glycollate oxidase (EC 1.1.3.15)
    Language English
    Publishing date 2020-11-10
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 208909-9
    ISSN 1432-2048 ; 0032-0935 ; 1866-2749
    ISSN (online) 1432-2048
    ISSN 0032-0935 ; 1866-2749
    DOI 10.1007/s00425-020-03504-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Bonn / Germany

    Z 46/303: Show issues

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  6. Article ; Online: (Some) current concepts in antibacterial drug discovery.

    van Geelen, Lasse / Meier, Dieter / Rehberg, Nidja / Kalscheuer, Rainer

    Applied microbiology and biotechnology

    2018  Volume 102, Issue 7, Page(s) 2949–2963

    Abstract: The rise of multidrug resistance in bacteria rendering pathogens unresponsive to many clinical drugs is widely acknowledged and considered a critical global healthcare issue. There is broad consensus that novel antibacterial chemotherapeutic options are ... ...

    Abstract The rise of multidrug resistance in bacteria rendering pathogens unresponsive to many clinical drugs is widely acknowledged and considered a critical global healthcare issue. There is broad consensus that novel antibacterial chemotherapeutic options are extremely urgently needed. However, the development pipeline of new antibacterial drug lead structures is poorly filled and not commensurate with the scale of the problem since the pharmaceutical industry has shown reduced interest in antibiotic development in the past decades due to high economic risks and low profit expectations. Therefore, academic research institutions have a special responsibility in finding novel treatment options for the future. In this mini review, we want to provide a broad overview of the different approaches and concepts that are currently pursued in this research field.
    MeSH term(s) Academies and Institutes/trends ; Anti-Bacterial Agents ; Drug Discovery ; Drug Industry/trends
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2018-02-17
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 392453-1
    ISSN 1432-0614 ; 0171-1741 ; 0175-7598
    ISSN (online) 1432-0614
    ISSN 0171-1741 ; 0175-7598
    DOI 10.1007/s00253-018-8843-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2229: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Das Spiel und sein Material als Grundlage von Symbolisierung und Übertragung in der analytischen Kinderpsychotherapie mit Fallbeispielen

    Meier, Dieter

    (In: Wiesse, Jörg (Ed.), Psychoanalyse und Kindheit (S. 94-113). Göttingen: Vandenhoeck & Ruprecht (Serie: Psychoanalytische Blätter, Band 28))

    2008  

    Abstract: Die Bedeutung des Spiels in der analytischen Kinderpsychotherapie wird erörtert. Nach einleitenden Anmerkungen zu J. Huizingas "Homo ludens - Vom Ursprung der Kultur im Spiel" (1956) wird zunächst der Begriff des Spiels im psychoanalytischen Kontext ... ...

    Title translation Games and their material as a fundament of symbolization and transference in analytical child psychotherapy with illustrative case reports
    Series title In: Wiesse, Jörg (Ed.), Psychoanalyse und Kindheit (S. 94-113). Göttingen: Vandenhoeck & Ruprecht (Serie: Psychoanalytische Blätter, Band 28)
    Abstract Die Bedeutung des Spiels in der analytischen Kinderpsychotherapie wird erörtert. Nach einleitenden Anmerkungen zu J. Huizingas "Homo ludens - Vom Ursprung der Kultur im Spiel" (1956) wird zunächst der Begriff des Spiels im psychoanalytischen Kontext geklärt. Spieltherapie wird verstanden als die Möglichkeit, schrittweise das innere konflikthafte Geschehen projektiv nach außen zu bringen, auf Spielmaterial oder spielerische Inszenierungen zu übertragen, wobei das Übertragungsgeschehen mehr oder minder als in der Übertragung befindliches Agieren gesehen werden kann. Nach dieser definitorischen Standortbestimmung werden einige Aspekte, die in Hinsicht auf Anwendung und Bedeutung der Spieltherapie besonders wichtig erscheinen, besprochen. Im Mittelpunkt steht dabei das Spiel als Repräsentanz der inneren Welt des Kindes bzw. des kindlichen Patienten. Anschließend wird der Versuch unternommen, verschiedene Spielmaterialien zu sammeln, nach verschiedenen Kriterien der Objekt- und Subjektbezogenheit zu ordnen und mögliche Erscheinungsweisen im therapeutischen Kontext zu diskutieren. Anhand von Fallvignetten wird das Spiel und das Spielmaterial als Ausdruck verschiedener Übertragungsmodi auf verschiedenen Entwicklungs- und Strukturebenen analysiert.
    Keywords Child Psychotherapy ; Childhood Play Behavior ; Kinderpsychotherapie ; Play Therapy ; Psychoanalysis ; Psychoanalytische Therapie ; Psychotherapeutic Transference ; Spieltherapie ; Spielverhalten bei Kindern ; Übertragung (Psychotherapie)
    Language German
    Document type Article
    Database PSYNDEX

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  8. Article ; Online: Polyketide Derivatives from Mangrove Derived Endophytic Fungus

    Yu, Xiaoqin / Müller, Werner E G / Meier, Dieter / Kalscheuer, Rainer / Guo, Zhiyong / Zou, Kun / Umeokoli, Blessing O / Liu, Zhen / Proksch, Peter

    Marine drugs

    2020  Volume 18, Issue 2

    Abstract: Chemical investigation of secondary metabolites from the endophytic ... ...

    Abstract Chemical investigation of secondary metabolites from the endophytic fungus
    MeSH term(s) Endophytes ; Fermentation ; Fungi/metabolism ; Magnetic Resonance Spectroscopy ; Models, Molecular ; Molecular Structure ; Polyketides/chemistry ; Polyketides/metabolism ; Rhizophoraceae/microbiology
    Chemical Substances Polyketides
    Language English
    Publishing date 2020-02-23
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175190-0
    ISSN 1660-3397 ; 1660-3397
    ISSN (online) 1660-3397
    ISSN 1660-3397
    DOI 10.3390/md18020129
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Natural brominated phenoxyphenols kill persistent and biofilm-incorporated cells of MRSA and other pathogenic bacteria

    van Geelen, Lasse / Kaschani, Farnusch / Sazzadeh, Shabnam S / Adeniyi, Emmanuel T / Meier, Dieter / Proksch, Peter / Pfeffer, Klaus / Kaiser, Markus / Ioerger, Thomas R / Kalscheuer, Rainer

    Applied microbiology and biotechnology. 2020 July, v. 104, no. 13

    2020  

    Abstract: Due to a high unresponsiveness to chemotherapy, biofilm formation is an important medical problem that frequently occurs during infection with many bacterial pathogens. In this study, the marine sponge-derived natural compounds 4,6-dibromo-2-(2′,4′- ... ...

    Abstract Due to a high unresponsiveness to chemotherapy, biofilm formation is an important medical problem that frequently occurs during infection with many bacterial pathogens. In this study, the marine sponge-derived natural compounds 4,6-dibromo-2-(2′,4′-dibromophenoxy)phenol and 3,4,6-tribromo-2-(2′,4′-dibromophenoxy)phenol were found to exhibit broad antibacterial activity against medically relevant gram-positive and gram-negative pathogens. The compounds were not only bactericidal against both replicating and stationary phase–persistent planktonic cells of methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa; they also killed biofilm-incorporated cells of both species while not affecting biofilm structural integrity. Moreover, these compounds were active against carbapenemase-producing Enterobacter sp. This simultaneous activity of compounds against different growth forms of both gram-positive and gram-negative bacteria is rare. Genome sequencing of spontaneous resistant mutants and proteome analysis suggest that resistance is mediated by downregulation of the bacterial EIIBC phosphotransferase components scrA and mtlA in MRSA likely leading to a lower uptake of the molecules. Due to their only moderate cytotoxicity against human cell lines, phenoxyphenols provide an interesting new scaffold for development of antimicrobial agents with activity against planktonic cells, persisters and biofilm-incoporated cells of ESKAPE pathogens. KEY POINTS: • Brominated phenoxyphenols kill actively replicating and biofilm-incorporated bacteria. • Phosphotransferase systems mediate uptake of brominated phenoxyphenols. • Downregulation of phosphotransferase systems mediate resistance.
    Keywords Enterobacter ; Pseudomonas aeruginosa ; antibacterial properties ; biofilm ; biotechnology ; bromination ; cytotoxicity ; drug therapy ; genome ; humans ; methicillin-resistant Staphylococcus aureus ; plankton ; proteome
    Language English
    Dates of publication 2020-07
    Size p. 5985-5998.
    Publishing place Springer Berlin Heidelberg
    Document type Article
    ZDB-ID 392453-1
    ISSN 1432-0614 ; 0171-1741 ; 0175-7598
    ISSN (online) 1432-0614
    ISSN 0171-1741 ; 0175-7598
    DOI 10.1007/s00253-020-10654-4
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Bonn / Germany

    Z 79/727: Show issues

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  10. Book: Entwicklung eines Verfahrens zur Fertigung laserstrukturierter metallisierter Folien für die Mikroelektronik

    Eger, Lutz / Meier, Dieter

    Abschlussbericht zu einem gemeinsamen Entwicklungsprojekt, gefördert von der Deutschen Bundesstiftung Umweltschutz unter dem Aktenzeichen 18961

    2005  

    Institution LPKF Laser & Electronics AG
    Author's details LPKF Laser & Electronics AG. Dieter Meier (Projektleiter). Unter Mitarb. von: Lutz Eger
    Language German
    Size 70 S, Ill., graph. Darst.
    Publishing place Garbsen
    Document type Book
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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