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  1. Book ; Thesis: Zwangsheirat

    Meier, Yvonne

    Rechtslage in der Schweiz ; Rechtsvergleich mit Deutschland und Österreich

    (Schriftenreihe zum Familienrecht ; 16)

    2010  

    Author's details Yvonne Meier
    Series title Schriftenreihe zum Familienrecht ; 16
    Keywords Rechtsvergleich ; Zwangsheirat ; Österreich ; Schweiz ; Deutschland
    Language German
    Size XLIV, 273 S., graph. Darst.
    Publisher Stämpfli
    Publishing place Bern
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Univ., Diss.--Zürich, 2010
    ISBN 9783727228643 ; 3727228644
    Database Former special subject collection: coastal and deep sea fishing

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  2. Book ; Online ; Thesis: Drug induced liver injury: Relevance of the interindividual differences in expression of the ABC-transporters

    Meier, Yvonne

    2005  

    Author's details by Yvonne Meier
    Language English
    Size Online-Ressource (117 S), Ill
    Publisher ETH
    Publishing place Zürich
    Document type Book ; Online ; Thesis
    Thesis / German Habilitation thesis Diss., Naturwissenschaften, Eidgenössische Technische Hochschule ETH Zürich, Nr. 16178--Zürich, 1617
    Database Former special subject collection: coastal and deep sea fishing

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  3. Book ; Thesis: Drug induced liver injury

    Meier, Yvonne

    relevance of the interindividual differences in expression of the ABC-transporters

    2005  

    Author's details by Yvonne Meier
    Language English
    Size 2 Mikrofiches, Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Eidgen. Techn. Hochschule, Diss.--Zürich, 2005
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  4. Book ; Online: Drug induced liver injury

    Meier, Yvonne

    Relevance of the interindividual differences in expression of the ABC-transporters

    2005  

    Abstract: Diss., Naturwissenschaften, Eidgenössische Technische Hochschule ETH Zürich, Nr. 16178, ... ...

    Abstract Diss., Naturwissenschaften, Eidgenössische Technische Hochschule ETH Zürich, Nr. 16178, 2005
    Keywords NEBENWIRKUNGEN VON ARZNEIMITTELN + BEHANDLUNGSKOMPLIKATIONEN ; LEBERKRANKHEITEN + LEBERSCHÄDEN ; ABC-TRANSPORTER (PROTEINE ; PEPTIDE) ; GENREGULATION ; REGULATION DER GENEXPRESSION (MOLEKULARBIOLOGIE)
    Language English
    Publisher Zürich, ETH
    Publishing country ch
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  5. Article ; Online: International and Racial Differences in Mineral and Bone Disorder Markers and Treatments Over the First 5 Years of Hemodialysis in the Dialysis Outcomes and Practice Patterns Study.

    Chan, Kevin / Karaboyas, Angelo / Morgenstern, Hal / Robinson, Bruce M / Port, Friedrich K / Jacobson, Stefan H / Fukagawa, Masafumi / Meier, Yvonne / Csomor, Philipp A / Pisoni, Ronald L

    Kidney medicine

    2019  Volume 1, Issue 3, Page(s) 86–96

    Abstract: Rationale & objective: Normalization of parathyroid hormone (PTH), serum calcium, and phosphorus levels may prevent coronary and bone disease in hemodialysis (HD) patients. We describe the trajectory of these mineral bone disorder parameters and ... ...

    Abstract Rationale & objective: Normalization of parathyroid hormone (PTH), serum calcium, and phosphorus levels may prevent coronary and bone disease in hemodialysis (HD) patients. We describe the trajectory of these mineral bone disorder parameters and treatments during the first 5 years of HD by international region and race.
    Study design: Prospective cohort study.
    Setting & participants: 33,517 US black/African American, US non-black/African American, European, and Japanese HD patients from the Dialysis Outcomes and Practice Patterns Study (DOPPS) phases 4 to 5 (2009-2015).
    Predictor: Time since HD initiation.
    Outcomes: Monthly cross-sections of mineral bone disorder parameters (PTH, serum calcium, and phosphorus) and medications (cinacalcet, active vitamin D, and phosphate binders).
    Results: Mean PTH levels declined precipitously during the first 4 months of HD in all 4 groups, then steadily increased during the next 4.5 years in the United States/Europe but not in Japan. 3 years after HD initiation (month 36), mean PTH level was highest in US black/African Americans (496 pg/mL), despite greater prescription of cinacalcet (23%) and active vitamin D (85%), and lowest in Japan (151 pg/mL). Mean serum calcium and phosphorus levels increased during the first 4 months of HD. By month 36, the mean calcium level was lower in Japan (8.8 mg/dL) than United States/Europe (9.0-9.1 mg/dL), while the mean phosphorus level was lower in Europe (4.8 mg/dL) than United States/Japan (5.1-5.3 mg/dL).
    Limitations: Lack of data for medication dosages; most patients were not followed from HD onset.
    Conclusions: Large differences exist in the levels, trajectories, and therapies for PTH, calcium, and phosphorus by country and race in the first 5 years of HD. Higher PTH levels were observed in the United States, especially among black/African American patients, despite greater use of cinacalcet and active vitamin D than in Japan or Europe. Potential contributors to differences in PTH levels should be explored to study their impact on PTH management strategies and consequent bone and cardiovascular complications.
    Language English
    Publishing date 2019-05-10
    Publishing country United States
    Document type Journal Article
    ISSN 2590-0595
    ISSN (online) 2590-0595
    DOI 10.1016/j.xkme.2019.04.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: The bile salt export pump.

    Stieger, Bruno / Meier, Yvonne / Meier, Peter J

    Pflugers Archiv : European journal of physiology

    2007  Volume 453, Issue 5, Page(s) 611–620

    Abstract: Canalicular secretion of bile salts mediated by the bile salt export pump Bsep constitutes the major driving force for the generation of bile flow. Bsep is a member of the B-family of the super family of ATP-binding cassette transporters and is ... ...

    Abstract Canalicular secretion of bile salts mediated by the bile salt export pump Bsep constitutes the major driving force for the generation of bile flow. Bsep is a member of the B-family of the super family of ATP-binding cassette transporters and is classified as ABCB11. Bsep has a narrow substrate specificity, which is largely restricted to bile salts. Bsep is extensively regulated at the transcriptional and posttranscriptional level, which directly modulates canalicular bile formation. Pathophysiological alterations of Bsep by either inherited mutations or acquired processes such as inhibition by drugs or disease-related down regulation may lead to a wide spectrum of mild to severe forms of liver disease. Furthermore, many genetic variants of Bsep are known, some of which potentially render individuals susceptible to acquired forms of liver disease.
    MeSH term(s) ATP Binding Cassette Subfamily B Member 11 ; ATP-Binding Cassette Transporters/antagonists & inhibitors ; ATP-Binding Cassette Transporters/genetics ; ATP-Binding Cassette Transporters/physiology ; Amino Acid Sequence ; Animals ; Bile Acids and Salts/metabolism ; Bile Canaliculi/physiology ; Cholestasis, Intrahepatic/genetics ; Gene Expression Regulation ; Humans ; Liver/embryology ; Mice ; Molecular Sequence Data ; RNA-Binding Proteins/physiology ; Rats ; Transcription, Genetic
    Chemical Substances ABCB11 protein, human ; ATP Binding Cassette Subfamily B Member 11 ; Abcb11 protein, mouse ; Bile Acids and Salts ; Fxr1h protein, mouse ; RNA-Binding Proteins
    Language English
    Publishing date 2007-02
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 6380-0
    ISSN 1432-2013 ; 0031-6768
    ISSN (online) 1432-2013
    ISSN 0031-6768
    DOI 10.1007/s00424-006-0152-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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  7. Article ; Online: Renal function in patients with non-dialysis chronic kidney disease receiving intravenous ferric carboxymaltose: an analysis of the randomized FIND-CKD trial.

    Macdougall, Iain C / Bock, Andreas H / Carrera, Fernando / Eckardt, Kai-Uwe / Gaillard, Carlo / Van Wyck, David / Meier, Yvonne / Larroque, Sylvain / Roger, Simon D

    BMC nephrology

    2017  Volume 18, Issue 1, Page(s) 24

    Abstract: Background: Preclinical studies demonstrate renal proximal tubular injury after administration of some intravenous iron preparations but clinical data on renal effects of intravenous iron are sparse.: Methods: FIND-CKD was a 56-week, randomized, open- ...

    Abstract Background: Preclinical studies demonstrate renal proximal tubular injury after administration of some intravenous iron preparations but clinical data on renal effects of intravenous iron are sparse.
    Methods: FIND-CKD was a 56-week, randomized, open-label, multicenter study in which patients with non-dialysis dependent chronic kidney disease (ND-CKD), anemia and iron deficiency without erythropoiesis-stimulating agent therapy received intravenous ferric carboxymaltose (FCM), targeting either higher (400-600 μg/L) or lower (100-200 μg/L) ferritin values, or oral iron.
    Results: Mean (SD) eGFR at baseline was 34.9 (11.3), 32.8 (10.8) and 34.2 (12.3) mL/min/1.73 m
    Conclusion: Intravenous FCM at doses that maintained ferritin levels of 100-200 μg/L or 400-600 μg/L did not negatively impact renal function (eGFR) in patients with ND-CKD over 12 months versus oral iron, and eGFR remained stable. These findings show no evidence of renal toxicity following intravenous FCM over a 1-year period.
    Trial registrations: ClinicalTrials.gov NCT00994318 (first registration 12 October 2009).
    Language English
    Publishing date 2017-01-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041348-8
    ISSN 1471-2369 ; 1471-2369
    ISSN (online) 1471-2369
    ISSN 1471-2369
    DOI 10.1186/s12882-017-0444-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Safety of intravenous ferric carboxymaltose versus oral iron in patients with nondialysis-dependent CKD: an analysis of the 1-year FIND-CKD trial.

    Roger, Simon D / Gaillard, Carlo A / Bock, Andreas H / Carrera, Fernando / Eckardt, Kai-Uwe / Van Wyck, David B / Cronin, Maureen / Meier, Yvonne / Larroque, Sylvain / Macdougall, Iain C

    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

    2017  Volume 32, Issue 9, Page(s) 1530–1539

    Abstract: Background: The evidence base regarding the safety of intravenous (IV) iron therapy in patients with chronic kidney disease (CKD) is incomplete and largely based on small studies of relatively short duration.: Methods: FIND-CKD (ClinicalTrials.gov ... ...

    Abstract Background: The evidence base regarding the safety of intravenous (IV) iron therapy in patients with chronic kidney disease (CKD) is incomplete and largely based on small studies of relatively short duration.
    Methods: FIND-CKD (ClinicalTrials.gov number NCT00994318) was a 1-year, open-label, multicenter, prospective study of patients with nondialysis-dependent CKD, anemia and iron deficiency randomized (1:1:2) to IV ferric carboxymaltose (FCM), targeting higher (400-600 µg/L) or lower (100-200 µg/L) ferritin, or oral iron. A post hoc analysis of adverse event rates per 100 patient-years was performed to assess the safety of FCM versus oral iron over an extended period.
    Results: The safety population included 616 patients. The incidence of one or more adverse events was 91.0, 100.0 and 105.0 per 100 patient-years in the high ferritin FCM, low ferritin FCM and oral iron groups, respectively. The incidence of adverse events with a suspected relation to study drug was 15.9, 17.8 and 36.7 per 100 patient-years in the three groups; for serious adverse events, the incidence was 28.2, 27.9 and 24.3 per 100 patient-years. The incidence of cardiac disorders and infections was similar between groups. At least one ferritin level ≥800 µg/L occurred in 26.6% of high ferritin FCM patients, with no associated increase in adverse events. No patient with ferritin ≥800 µg/L discontinued the study drug due to adverse events. Estimated glomerular filtration rate remained the stable in all groups.
    Conclusions: These results further support the conclusion that correction of iron deficiency anemia with IV FCM is safe in patients with nondialysis-dependent CKD.
    MeSH term(s) Administration, Intravenous ; Administration, Oral ; Aged ; Anemia, Iron-Deficiency/drug therapy ; Anemia, Iron-Deficiency/etiology ; Female ; Ferric Compounds/administration & dosage ; Glomerular Filtration Rate ; Humans ; Iron/administration & dosage ; Male ; Maltose/administration & dosage ; Maltose/analogs & derivatives ; Prospective Studies ; Renal Insufficiency, Chronic/complications ; Time Factors
    Chemical Substances Ferric Compounds ; ferric carboxymaltose (6897GXD6OE) ; Maltose (69-79-4) ; Iron (E1UOL152H7)
    Language English
    Publishing date 2017-03-23
    Publishing country England
    Document type Journal Article ; Multicenter Study ; Randomized Controlled Trial
    ZDB-ID 90594-x
    ISSN 1460-2385 ; 0931-0509
    ISSN (online) 1460-2385
    ISSN 0931-0509
    DOI 10.1093/ndt/gfw264
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2198: Show issues Location:
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  9. Article: Erythropoietic response to oral iron in patients with nondialysis-dependent chronic kidney disease in the FIND-CKD trial
.

    Macdougall, Iain C / Bock, Andreas H / Carrera, Fernando / Eckardt, Kai-Uwe / Gaillard, Carlo / Wyck, David Van / Meier, Yvonne / Larroque, Sylvain / Perrin, Amandine / Roger, Simon D

    Clinical nephrology

    2017  Volume 88, Issue 12, Page(s) 301–310

    Abstract: Aims: To evaluate erythropoietic response rates to oral iron over time in iron-deficient anemic patients with nondialysis-dependent chronic kidney disease (ND-CKD).: Materials and methods: FIND-CKD was a 1-year, randomized, multicenter trial of iron ... ...

    Abstract Aims: To evaluate erythropoietic response rates to oral iron over time in iron-deficient anemic patients with nondialysis-dependent chronic kidney disease (ND-CKD).
    Materials and methods: FIND-CKD was a 1-year, randomized, multicenter trial of iron therapy in patients with ND-CKD, anemia, and iron deficiency, without erythropoiesis-stimulating agent (ESA) therapy. Patients with active infection or C-reactive protein > 20 mg/L were excluded. In this post-hoc analysis, response was defined as ≥ 1 g/dL increase in hemoglobin (Hb) from baseline, before initiation of alternative anemia therapy (i.e., ESA, transfusion, or intravenous iron).
    Results: 308 patients received oral iron (200 mg elemental iron/day). Mean (SD) Hb at baseline was 10.4 (0.7) g/dL. At week 4, Hb data were available from 292 patients without alternative anemia therapy: 63/292 (21.6%) showed a response. Among the 229 nonresponders at week 4, 48.8% showed a cumulative response on ≥ 1 occasion by week 52 (11.1%, 19.9%, 25.9%, and 28.7% had a response at weeks 8, 12, 24, and 52, respectively), and 27.9% had received alternative iron therapy by week 52. Baseline levels of Hb, ferritin, and transferrin saturation were lower in responders than in nonresponders. Neither concomitant medication nor adherence (as assessed by medication count) was substantially different between early responders and nonresponders.
    Conclusion: Four weeks after starting oral iron therapy, only 21.6% of anemic patients with ND-CKD and iron deficiency showed an Hb increase of at least 1 g/dL. Among early nonresponders, < 30% responded at any subsequent time point. Earlier consideration of alternative therapy could improve anemia management in this population.
.
    Language English
    Publishing date 2017-12
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 185101-9
    ISSN 0301-0430
    ISSN 0301-0430
    DOI 10.5414/CN109198
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 873: Show issues Location:
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  10. Book ; Online: Footnotes

    Alexander, Elena / Dunn, Douglas / Gamso, Marjorie / Houston-Jones, Ishmael / Johnston, Jill / King, Kenneth / Meier, Yvonne / Skaggs, Sarah

    Six Choreographers Inscribe the Page

    (Critical Voices in Art, Theory and Culture)

    2013  

    Abstract: First published in ... ...

    Series title Critical Voices in Art, Theory and Culture
    Abstract First published in 1998
    Language English
    Size Online-Ressource (255 p)
    Publisher Taylor and Francis
    Publishing place Hoboken
    Document type Book ; Online
    Note Description based upon print version of record
    ISBN 9789057010422 ; 9057010429
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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