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Article ; Online: Recent Advances of MXene-Based Electrochemical Immunosensors

Meiqing Yang / Haozi Lu / Song Liu

Applied Sciences, Vol 12, Iss 5630, p

2022 Volume 5630

Abstract: Electrochemical immunosensors are the largest class of affinity biosensing devices with strong practicability. In recent years, MXenes have become hotspot materials of electrochemical biosensors for their excellent properties, including large specific ... ...

Abstract	Electrochemical immunosensors are the largest class of affinity biosensing devices with strong practicability. In recent years, MXenes have become hotspot materials of electrochemical biosensors for their excellent properties, including large specific surface area, good electrical conductivity, high hydrophilicity and rich functional groups. In this review, we firstly introduce the composition and structure of MXenes, as well as their properties relevant to the construction of biosensors. Then, we summarize the recent advances of MXenes-based electrochemical immunosensors, focusing on the roles of MXenes in various electrochemical immunosensors. Finally, we analyze current problems of MXenes-based electrochemical immunosensors and propose an outlook for this research field.
Keywords	MXenes ; electrochemical immunosensors ; electrode-modified nanomaterials ; labels ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
Language	English
Publishing date	2022-06-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Comprehensive analyses of genetic diversities and population structure of the Guizhou Dong group based on 44 Y-markers

Hongling Zhang / Xiaolan Huang / Xiaoye Jin / Zheng Ren / Qiyan Wang / Meiqing Yang / Ronglan Xu / Xiang Yuan / Daiquan Yang / Hongyan Liu / Wanyi Shen / Huiying Zhang / Yangjie Que / Jiang Huang

PeerJ, Vol 11, p e

2023 Volume 16183

Abstract: Background The non-recombining region of the human Y chromosome (NRY) is a strictly paternally inherited genetic marker and the best material to trace the paternal lineages of populations. Y chromosomal short tandem repeat (Y-STR) is characterized by ... ...

Abstract	Background The non-recombining region of the human Y chromosome (NRY) is a strictly paternally inherited genetic marker and the best material to trace the paternal lineages of populations. Y chromosomal short tandem repeat (Y-STR) is characterized by high polymorphism and paternal inheritance pattern, so it has been widely used in forensic medicine and population genetic research. This study aims to understand the genetic distribution of Y-STRs in the Guizhou Dong population, provide reference data for forensic application, and explore the phylogenetic relationships between the Guizhou Dong population and other comparison populations. Methods Based on the allele profile of 44 Y-markers in the Guizhou Dong group, we estimate their allele frequencies and haplotype frequencies. In addition, we also compare the forensic application efficiency of different Y-STR sets in the Guizhou Dong group. Finally, genetic relationships among Guizhou Dong and other reference populations are dissected by the multi-dimensional scaling and the phylogenetic tree. Results A total of 393 alleles are observed in 312 Guizhou Dong individuals for these Y-markers, with allele frequencies ranging from 0.0032 to 0.9679. The haplotype diversity and discriminatory capacity for these Y-markers in the Guizhou Dong population are 0.99984 and 0.97440, respectively. The population genetic analyses of the Guizhou Dong group and other reference populations show that the Guizhou Dong group has the closest genetic relationship with the Hunan Dong population, and followed by the Guizhou Tujia population. Conclusions In conclusion, these 44 Y-markers can be used as an effective tool for male differentiation in the Guizhou Dong group. The haplotype data in this study not only enrich the Y-STR data of different ethnic groups in China, but also have important significance for population genetics and forensic research.
Keywords	Guizhou Dong ; Forensic features ; Population genetics ; STR ; Y-chromosome ; Medicine ; R ; Biology (General) ; QH301-705.5
Subject code	590
Language	English
Publishing date	2023-09-01T00:00:00Z
Publisher	PeerJ Inc.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Genetic features and phylogenetic relationship analyses of Guizhou Han population residing in Southwest China via 38 X-InDels

Yuhang Feng / Ting Wang / Yunteng Yang / Jiangtao You / Kun He / Hongling Zhang / Qiyan Wang / Meiqing Yang / Jiang Huang / Zheng Ren / Xiaoye Jin

PeerJ, Vol 11, p e

2023 Volume 14964

Abstract: Background The insertion/deletion polymorphism (InDel), an ideal forensic genetic marker with a low spontaneous mutation rate and small amplification product fragments, is widely distributed in the genome, combining the advantages of STR and SNP genetic ... ...

Abstract	Background The insertion/deletion polymorphism (InDel), an ideal forensic genetic marker with a low spontaneous mutation rate and small amplification product fragments, is widely distributed in the genome, combining the advantages of STR and SNP genetic markers. The X-chromosome has high application value in complex paternity testing, and it is an excellent system for evaluating population admixture and studying evolutionary anthropology. However, further research is needed on the population genetics of X-chromosome InDels (X-InDels). Methods In this article, a system composed of 38 X-InDel loci was utilized to analyse and evaluate the forensic parameters of the Guizhou Han population in order to explore its forensic application efficiency. Results The results showed that expected heterozygosities spanned from 0.0189 to 0.5715, and the cumulative power of discrimination of the 32 X-InDels and three linkage blocks was 0.9999999954 and 0.999999999999741 for males and females, respectively. The combined mean exclusion chance of these loci for trios and duos is 0.999999 and 0.999747, respectively. Multiple methods like principal component analysis, Fst genetic distance, and phylogenetic reconstruction were employed for dissecting the genetic structure of the Guizhou Han population by comparing it with previously reported populations. As expected, the studied Han population displayed relatively close genetic affinities with the East Asian populations. At the same time, there were obvious genetic differentiations between the Guizhou Han population and other continental populations that were discerned, especially for the African populations. Conclusions This study further verified the applicability of 38 X-InDels for human personal identification and kinship analyses of Han Chinese, and also showed the application potential of X-InDels in population genetics.
Keywords	Guizhou Han ; Forensic features ; Population genetics ; InDel ; X-chromosome ; Medicine ; R ; Biology (General) ; QH301-705.5
Subject code	590
Language	English
Publishing date	2023-03-01T00:00:00Z
Publisher	PeerJ Inc.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Recent advances of MXenes as electrocatalysts for hydrogen evolution reaction

Saishuai Bai / Meiqing Yang / Jizhou Jiang / Xiaomiao He / Jing Zou / Zhiguo Xiong / Guodong Liao / Song Liu

npj 2D Materials and Applications, Vol 5, Iss 1, Pp 1-

2021 Volume 15

Abstract: Abstract MXenes, an emerging two-dimensional (2D) transition metal carbides, nitrides and carbonitrides, have exhibited great potential as electrocatalysts for hydrogen evolution reaction (HER) due to the excellent characters, including excellent ... ...

Abstract	Abstract MXenes, an emerging two-dimensional (2D) transition metal carbides, nitrides and carbonitrides, have exhibited great potential as electrocatalysts for hydrogen evolution reaction (HER) due to the excellent characters, including excellent structural and chemical stability, superior electrical conductivity, and large active surface area. In this comprehensive study, firstly, the preparation advances of MXenes are systematically summarized. Then, the representative applications of MXenes-based HER electrocatalysts are introduced, from experimental and theoretical aspects. Thirdly, the strategies for improving HER catalytic activity of MXenes are demonstrated, such as optimizing active sites by termination modification and metal-atom doping, increasing active sites by fabricating various nanostructures. Finally, the existing challenges and new opportunities for MXenes-based electrocatalysts are also elucidated. This paper provides reference for the future development of new and efficient MXenes-based electrocatalysts for hydrogen production through water-splitting technology.
Keywords	Materials of engineering and construction. Mechanics of materials ; TA401-492 ; Chemistry ; QD1-999
Subject code	540
Language	English
Publishing date	2021-09-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Genetic Admixture History and Forensic Characteristics of Guizhou Sui People Inferred From Autosomal Insertion/Deletion and Genome-Wide Single-Nucleotide Polymorphisms

Meiqing Yang / Xiaomin Yang / Zheng Ren / Guanglin He / Han Zhang / Qiyang Wang / Yubo Liu / Hongling Zhang / Jingyan Ji / Jing Chen / Jianxin Guo / Jiang Huang / Chuan-Chao Wang

Frontiers in Ecology and Evolution, Vol

2022 Volume 10

Abstract: Insertion-deletion (Indel) serves as one of the important markers in forensic personal identification and parentage testing, especially for cases with degraded samples. However, the genetic diversity and forensic features in ethnolinguistically diverse ... ...

Abstract	Insertion-deletion (Indel) serves as one of the important markers in forensic personal identification and parentage testing, especially for cases with degraded samples. However, the genetic diversity and forensic features in ethnolinguistically diverse southwestern Chinese populations remain to be explored. Sui, one Tai-Kadai-speaking population residing in Guizhou, has a complex genetic history based on linguistic, historic, and anthropological evidence. In this study, we genotyped 30 Indels from 511 Guizhou Sui individuals and obtained approximately 700,000 genome-wide single-nucleotide polymorphisms (SNPs) in 15 representative Sui individuals to comprehensively characterize the genetic diversity, forensic characteristics, and genomic landscape of Guizhou Sui people. The estimated forensic statistically allele frequency spectrum and parameters demonstrated that this Indels panel was polymorphic and informative in Tai-Kadai populations in southern China. Results of principal component analysis (PCA), STRUCTURE, and phylogenetic trees showed that Guizhou Sui had a close genetic relationship with geographically close Tai-Kadai and Hmong-Mien people. Furthermore, genomic analysis based on the Fst and f4-statistics further suggested the genetic affinity within southern Chinese Tai-Kadai-speaking populations and a close relationship with geographically adjoining Guizhou populations. Admixture models based on the ADMIXTURE, f4, three-way qpAdm, and ALDER results demonstrated the interaction between the common ancestor for Tai-Kadai/Austronesian, Hmong-Mien, and Austroasiatic speaking populations played a significant role in the formation of modern Tai-Kadai people. We observed a sex-biased influence in Sui people by finding that the dominant Y chromosomal type was a Hmong-Mien specific lineage O2a2a1a2a1a2-N5 but the mtDNA lineages were commonly found in Tai-Kadai populations. The additional southward expansion of millet farmers in the Yellow River Basin has impacted the gene pool of southern populations including ...
Keywords	Sui ; InDel ; genome-wide data ; genetic profile ; demographic history ; Evolution ; QH359-425 ; Ecology ; QH540-549.5
Subject code	580
Language	English
Publishing date	2022-05-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Genomic Insights Into the Unique Demographic History and Genetic Structure of Five Hmong-Mien-Speaking Miao and Yao Populations in Southwest China

Meiqing Yang / Guanglin He / Zheng Ren / Qiyan Wang / Yubo Liu / Hongling Zhang / Han Zhang / Jing Chen / Jingyan Ji / Jing Zhao / Jianxin Guo / Kongyang Zhu / Xiaomin Yang / Rui Wang / Hao Ma / Chuan-Chao Wang / Jiang Huang

Frontiers in Ecology and Evolution, Vol

2022 Volume 10

Abstract: Southern China was the original center of multiple ancestral populations related to modern Hmong-Mien, Tai-Kadai, Austroasiatic, and Austronesian people. More recent genetic surveys have focused on the fine-scale genetic structure and admixture history ... ...

Abstract	Southern China was the original center of multiple ancestral populations related to modern Hmong-Mien, Tai-Kadai, Austroasiatic, and Austronesian people. More recent genetic surveys have focused on the fine-scale genetic structure and admixture history of southern Chinese populations, but the genetic formation and diversification of Hmong-Mien speakers are far from clear due to the sparse genetic sampling. Here, we reported nearly 700,000 single-nucleotide polymorphisms (SNPs) data from 130 Guizhou Miao and Yao individuals. We used principal component analysis, ADMIXTURE, f-statistics, qpAdm, phylogenetic tree, fineSTRUCTURE, and ALDER to explore the fine-scale population genetic structure and admixture pattern of Hmong-Mien people. The sharing allele patterns showed that our studied populations had a strong genetic affinity with ancient and modern groups from southern and southeastern East Asia. We identified one unique ancestry component maximized in Yao people, which widely existed in other Hmong-Mien-speaking populations in southern China and Southeast Asia and ancient samples of Guangxi. Guizhou Hmong-Mien speakers harbored the dominant proportions of ancestry related to southern indigenous East Asians and minor proportions of northern ancestry related to Yellow River farmers, suggesting the possibility of genetic admixture between Hmong-Mien people and recent southward Sino-Tibetan-related populations. Furthermore, we found a genetic substructure among geographically different Miao and Yao people in Leishan and Songtao. The Yao and Miao people in Leishan harbored more southern East Asian ancestry, but Miao in Songtao received more northern East Asian genetic influence. We observed high mtDNA but low Y-chromosome diversity in studied Hmong-Mien groups, supporting the role of sex-specific residence in influencing human genetic variation. Our data provide valuable clues for further exploring population dynamics in southern China.
Keywords	Hmong-Mien people ; Miao and Yao ; genetic structure ; admixture ; genome-wide SNP data ; Evolution ; QH359-425 ; Ecology ; QH540-549.5
Subject code	950
Language	English
Publishing date	2022-06-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Identity and distribution of weedy Pedicularis kansuensis Maxim. (Orobanchaceae) in Tianshan Mountains of Xinjiang: morphological, anatomical and molecular evidence

Sui, Xiaolin / Airong Li / Kaiyun Guan / Meiqing Yang / Patrick Kuss / Wenjun Li

Journal of Arid Land. 2016 June, v. 8, no. 3

2016

Abstract: Weedy plants affect the biodiversity and ecosystem function as well as the crop and fodder plant production. However, adequate management requires detailed knowledge of the taxonomic identity of these plants. Here, we focused on a hemiparasitic ... ...

Abstract	Weedy plants affect the biodiversity and ecosystem function as well as the crop and fodder plant production. However, adequate management requires detailed knowledge of the taxonomic identity of these plants. Here, we focused on a hemiparasitic Pedicularis species (Orobanchaceae), which occurs at high densities and results in significant biomass reductions in forage grasses in Bayanbulak Grassland of Xinjiang. The identity of this target species is not clear, with conflicting reports in publications and in herbarium collections. Hence, clear and management-relevant information on demography and reproductive ecology is difficult to be obtained from the literature. Therefore, we analyzed field and archival materials collected from Xinjiang in order to clarify the identity and distribution of the target species. Morphological analyses suggested that the populations at Bayanbulak Grassland should be Pedicularis kansuensis Maxim. rather than P. verticillata L. which has been accepted in the available literature. Phylogenetic analysis with a combination of three barcodes (matK, rbcL and trnH-psbA) uniting a clade of P. kansuensis and individuals from Bayanbulak Grassland populations with 100% bootstrap support, confirmed the target species to be P. kansuensis. Anatomical investigations and field observations showed that the target species is an annual or biennial herb, which also fits with the life cycle as P. kansuensis. Based on archive material and field observations, we verified that the distribution of P. kansuensis is mainly concentrated in the Tianshan Mountains of Xinjiang.
Keywords	arid lands ; barcoding ; biodiversity ; biomass ; demography ; ecological function ; forage grasses ; grasslands ; herbaria ; mountains ; Pedicularis ; phylogeny ; China
Language	English
Dates of publication	2016-06
Size	p. 453-461.
Publishing place	Science Press
Document type	Article
ZDB-ID	2730950-2
ISSN	1674-6767
ISSN	1674-6767
DOI	10.1007/s40333-016-0004-0
Database	NAL-Catalogue (AGRICOLA)

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Article: Performance of a zero valent iron-based anaerobic system in swine wastewater treatment

Wu, Donglei / Shuangshuang Zheng / Aqiang Ding / Guodong Sun / Meiqing Yang

Journal of hazardous materials. 2015 Apr. 09, v. 286

2015

Abstract: In this paper, short-term exposure experiments with different ZVI concentrations were conducted to research the effects of ZVI adding on the anaerobic system for treating swine wastewater. Increasing the ZVI dose had a stimulatory effect on COD removal ... ...

Abstract	In this paper, short-term exposure experiments with different ZVI concentrations were conducted to research the effects of ZVI adding on the anaerobic system for treating swine wastewater. Increasing the ZVI dose had a stimulatory effect on COD removal and CH4 production possibly due to a higher corrosion-induced H2 and dissolved ferrous ions, which could stimulate the methanogenesis and thus the biodegradation. In addition, the abiotic corrosion reactions such as flocculation, adsorption and precipitation were inevitable to removal some suspended COD. However, high ZVI doses had a potential risk on microorganism due to the present of large numbers of solid iron species in sludge, which likely encapsulated the cells and even damaged the cellular structure. Taken as a whole, the most enhancing effect induced by ZVI was observed at the rZVI/VSS of 2.63, and the maximum efficiency of per ZVI adding occurred at the rZVI/VSS of 0.74. But the ZVI concentration of 50g/L (the rZVI/VSS was 5.26) was proved too high to facilitate microorganism activity, considering the higher LDH leakage and lower intracellular ATP level than the only sludge system.
Keywords	adenosine triphosphate ; adsorption ; biodegradation ; cell structures ; chemical oxygen demand ; corrosion ; flocculation ; ions ; methane production ; microbial activity ; risk ; sludge ; swine ; wastewater ; wastewater treatment
Language	English
Dates of publication	2015-0409
Size	p. 1-6.
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	1491302-1
ISSN	1873-3336 ; 0304-3894
ISSN (online)	1873-3336
ISSN	0304-3894
DOI	10.1016/j.jhazmat.2014.12.029
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Population genetic analysis of 36 Y-chromosomal STRs yields comprehensive insights into the forensic features and phylogenetic relationship of Chinese Tai-Kadai-speaking Bouyei.

Ya Luo / Yan Wu / Enfang Qian / Qian Wang / Qiyan Wang / Hongling Zhang / Xiaojuan Wang / Han Zhang / Meiqing Yang / Jingyan Ji / Zheng Ren / Ying Zhang / Jing Tang / Jiang Huang

PLoS ONE, Vol 14, Iss 11, p e

2019 Volume 0224601

Abstract: Male-specifically inherited Y-STRs, harboring the features of haploidy and lack of crossing over, have gained considerable attention in population genetics and forensic investigations. Goldeneye® Y-PLUS kit was a recently developed amplification system ... ...

Abstract	Male-specifically inherited Y-STRs, harboring the features of haploidy and lack of crossing over, have gained considerable attention in population genetics and forensic investigations. Goldeneye® Y-PLUS kit was a recently developed amplification system focused on the genetic diversity of 36 Y-chromosomal short tandem repeats (Y-STRs) in East Asians. However, no population data and corresponding forensic features were reported in China. Here, 36 Y-STRs were first genotyped in 400 unrelated healthy Tai-Kadai-speaking Bouyei male individuals. A total of 371 alleles and 396 haplotypes could be detected, and the allelic frequencies ranged from 0.0025 to 0.9875. The haplotype diversity, random match probability and discrimination capacity values were 0.9999, 0.0026 and 0.9900, respectively. The gene diversity (GD) of 36 Y-STR loci in the studied group ranged from 0.0248 (DYS645) to 0.9601 (DYS385a/b). Population comparisons between the Guizhou Bouyei and 80 reference groups were performed via the AMOVA, MDS, and phylogenetic relationship reconstruction. The results showed that the population stratification was almost consistent with the geographic distribution and language-family, both among Chinese and worldwide ethnic groups. Our newly genotyped Bouyei samples show a close affinity with other Tai-Kadai-speaking groups in China and Southeast Asia. Our data may provide useful information for paternal lineage in the forensic application and population genetics, as well as evidence for archaeological and historical research.
Keywords	Medicine ; R ; Science ; Q
Subject code	590
Language	English
Publishing date	2019-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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