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  1. Article: Teaching Microbiology by Celebrating Traditional Foods and Cultures from Morocco and Perú.

    Meléndez, Johana

    Journal of microbiology & biology education

    2019  Volume 20, Issue 1

    Abstract: According to a report published by the Center for Community College Student Engagement and others, global learning is considered one of the high-impact practices used to increase student engagement and motivation to learn. Engagement and motivation have ... ...

    Abstract According to a report published by the Center for Community College Student Engagement and others, global learning is considered one of the high-impact practices used to increase student engagement and motivation to learn. Engagement and motivation have also been linked to increased learning gains and improvement in the overall learning experience. Furthermore, global learning helps students explore other people's cultures and worldviews, which is an important skill for students to gain in order to compete and adapt to solve the problems of our global society. Here, I discuss two class activities that faculty can adopt to implement global learning in their courses, with the purpose of engaging and motivating students to learn microbiology while celebrating some traditions from Morocco and Perú. Students researched traditional fermented foods and drinks from Perú and Morocco. Then, they answered guided questions to help them link the food items to microbiological concepts learned in class. For example: normal flora and fermentation were learned as students researched the process of making a Peruvian drink called "
    Language English
    Publishing date 2019-04-26
    Publishing country United States
    Document type Journal Article
    ISSN 1935-7877
    ISSN 1935-7877
    DOI 10.1128/jmbe.v20i1.1685
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  2. Article: Senescence and fibrosis in salivary gland aging and disease.

    Nelson, Deirdre A / Kazanjian, Isabella / Melendez, J Andres / Larsen, Melinda

    Journal of oral biology and craniofacial research

    2024  Volume 14, Issue 3, Page(s) 231–237

    Abstract: Salivary gland hypofunction is highly prevalent in aged and diseased individuals leading to significant discomfort and morbidity. One factor that contributes to salivary gland hypofunction is cellular aging, or senescence. Senescent cells can impair ... ...

    Abstract Salivary gland hypofunction is highly prevalent in aged and diseased individuals leading to significant discomfort and morbidity. One factor that contributes to salivary gland hypofunction is cellular aging, or senescence. Senescent cells can impair gland function by secreting paracrine-acting growth factors and cytokines, known as senescence-associated secretory phenotype (SASP) factors. These SASP factors stimulate inflammation, propagate the senescent phenotype through the bystander effect, and stimulate fibrosis. As senotherapeutics that target senescent cells have shown effectiveness in limiting disease manifestations in other conditions, there is interest in the use of these drugs to treat salivary gland hypofunction. In this review, we highlight the contribution of senescence and fibrosis to salivary gland pathologies. We also discuss therapeutic approaches to eliminate or modulate the senescent SASP phenotype for treating age-related salivary gland diseases and extending health span.
    Language English
    Publishing date 2024-03-13
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2212-4268
    ISSN 2212-4268
    DOI 10.1016/j.jobcr.2024.02.009
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  3. Article ; Online: Multispectral Mid-Infrared Camera System for Accurate Stand-Off Temperature and Column Density Measurements on Flames.

    Meléndez, Juan / Guarnizo, Guillermo

    Sensors (Basel, Switzerland)

    2021  Volume 21, Issue 24

    Abstract: Accurate measurement of temperature in flames is a challenging problem that has been successfully addressed by hyperspectral imaging. This technique is able to provide maps of not only temperature T (K) but also of column density Q (ppm·m) of the main ... ...

    Abstract Accurate measurement of temperature in flames is a challenging problem that has been successfully addressed by hyperspectral imaging. This technique is able to provide maps of not only temperature T (K) but also of column density Q (ppm·m) of the main chemical species. Industrial applications, however, require cheaper instrumentation and faster and simpler data analysis. In this work, the feasibility and performance of multispectral imaging for the retrieval of T and QCO2 in flames are studied. Both the hyperspectral and multispectral measurement methods are described and applied to a standard flame, with known T and QCO2, and to an ordinary Bunsen flame. Hyperspectral results, based on emission spectra with 0.5 cm-1 resolution, were found in previous works to be highly accurate, and are thus considered as the ground truth to compare with multispectral measurements of a mid-IR camera (3 to 5 μm) with a six interference filter wheel. Maps of T and Q obtained by both methods show that, for regions with T ≳1300 K, the average of relative errors in multispectral measurements is ∼5% for T (and can be reduced to ∼2.5% with a correction based on a linear regression) and ∼20% for Q. Results obtained with four filters are very similar; results with two filters are also similar for T but worse for Q.
    Language English
    Publishing date 2021-12-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s21248395
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  4. Article ; Online: Fast Quantification of Air Pollutants by Mid-Infrared Hyperspectral Imaging and Principal Component Analysis.

    Meléndez, Juan / Guarnizo, Guillermo

    Sensors (Basel, Switzerland)

    2021  Volume 21, Issue 6

    Abstract: An imaging Fourier-transform spectrometer in the mid-infrared (1850-6667 cm-1) has been used to acquire transmittance spectra at a resolution of 1 cm-1 of three atmospheric pollutants with known column densities (Q): methane (258 ppm·m), nitrous oxide ( ... ...

    Abstract An imaging Fourier-transform spectrometer in the mid-infrared (1850-6667 cm-1) has been used to acquire transmittance spectra at a resolution of 1 cm-1 of three atmospheric pollutants with known column densities (Q): methane (258 ppm·m), nitrous oxide (107.5 ppm·m) and propane (215 ppm·m). Values of Q and T have been retrieved by fitting them with theoretical spectra generated with parameters from the HITRAN database, based on a radiometric model that takes into account gas absorption and emission, and the instrument lineshape function. A principal component analysis (PCA) of experimental data has found that two principal components are enough to reconstruct gas spectra with high fidelity. PCA-processed spectra have better signal-to-noise ratio without loss of spatial resolution, improving the uniformity of retrieval. PCA has been used also to speed up retrieval, by pre-calculating simulated spectra for a range of expected Q and T values, applying PCA to them and then comparing the principal components of experimental spectra with those of the simulated ones to find the gas Q and T values. A reduction in calculation time by a factor larger than one thousand is achieved with improved accuracy. Retrieval can be further simplified by obtaining T and Q as quadratic functions of the two first principal components.
    Language English
    Publishing date 2021-03-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s21062092
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  5. Article ; Online: Erratum: Large-scale kinetic roughening behavior of coffee-ring fronts [Phys. Rev. E 106, 044801 (2022)].

    Barreales, B G / Meléndez, J J / Cuerno, R / Ruiz-Lorenzo, J J

    Physical review. E

    2024  Volume 109, Issue 3-2, Page(s) 39901

    Abstract: This corrects the article DOI: 10.1103/PhysRevE.106.044801. ...

    Abstract This corrects the article DOI: 10.1103/PhysRevE.106.044801.
    Language English
    Publishing date 2024-04-18
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 2844562-4
    ISSN 2470-0053 ; 2470-0045
    ISSN (online) 2470-0053
    ISSN 2470-0045
    DOI 10.1103/PhysRevE.109.039901
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  6. Article ; Online: Virtual Spectral Selectivity in a Modulated Thermal Infrared Emitter with Lock-In Detection.

    Santalices, David / Meléndez, Juan / Briz, Susana

    Sensors (Basel, Switzerland)

    2022  Volume 22, Issue 14

    Abstract: The need for affordable low-power devices has led MEMS-based thermal emitters to become an interesting option for optical gas sensors. Since these emitters have a low thermal mass, they can be easily modulated and combined with a lock-in amplifier for ... ...

    Abstract The need for affordable low-power devices has led MEMS-based thermal emitters to become an interesting option for optical gas sensors. Since these emitters have a low thermal mass, they can be easily modulated and combined with a lock-in amplifier for detection. In this paper, we show that the signal measured by a lock-in amplifier from a thermal emitter that varies its temperature periodically can have different spectral profiles, depending on the reference signal used. These virtual emitters appear because the Fourier series expansion of the emitted radiance, as a function of time, has different coefficients for each wavelength, and this spectral signature, which is different for each harmonic, can be retrieved using a reference signal that corresponds to its frequency. In this study, the effect is first proved theoretically and then is measured experimentally. For this purpose, we performed measurements with an IR camera provided with six different spectral filters of a modulated emitter, in combination with lock-in amplification via software. Finally, we show a potential application of this effect using multiple virtual emitters to gain spectral selectivity and distinguish between two gases, CO2 and CH4.
    Language English
    Publishing date 2022-07-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s22145451
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  7. Article ; Online: Vaginal hysterectomy and training.

    Melendez, Joan

    International urogynecology journal

    2015  Volume 26, Issue 4, Page(s) 621

    MeSH term(s) Female ; Humans ; Hysterectomy, Vaginal/trends ; Uterine Diseases/surgery
    Language English
    Publishing date 2015-04
    Publishing country England
    Document type Comment ; Letter
    ZDB-ID 1050631-7
    ISSN 1433-3023 ; 0937-3462
    ISSN (online) 1433-3023
    ISSN 0937-3462
    DOI 10.1007/s00192-014-2611-7
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3070: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  8. Article ; Online: Re: Laparoscopic morcellation: an acceptable risk or an Achilles heel? Are there safer alternatives to morcellation?

    Melendez, J / Yoong, W

    BJOG : an international journal of obstetrics and gynaecology

    2015  Volume 122, Issue 9, Page(s) 1275

    MeSH term(s) Contraindications ; Female ; Humans ; Hysterectomy/adverse effects ; Laparoscopy ; Leiomyoma/surgery ; Surgical Instruments ; Uterine Myomectomy/methods ; Uterine Neoplasms/surgery
    Language English
    Publishing date 2015-08
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2000931-8
    ISSN 1471-0528 ; 0306-5456 ; 1470-0328
    ISSN (online) 1471-0528
    ISSN 0306-5456 ; 1470-0328
    DOI 10.1111/1471-0528.13492
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    In stock of ZB MED Cologne/Königswinter

    Um I Zs.121: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
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  9. Article: The importance of estradiol for body weight regulation in women.

    Vigil, Pilar / Meléndez, Jaime / Petkovic, Grace / Del Río, Juan Pablo

    Frontiers in endocrinology

    2022  Volume 13, Page(s) 951186

    Abstract: Obesity in women of reproductive age has a number of adverse metabolic effects, including Type II Diabetes (T2D), dyslipidemia, and cardiovascular disease. It is associated with increased menstrual irregularity, ovulatory dysfunction, development of ... ...

    Abstract Obesity in women of reproductive age has a number of adverse metabolic effects, including Type II Diabetes (T2D), dyslipidemia, and cardiovascular disease. It is associated with increased menstrual irregularity, ovulatory dysfunction, development of insulin resistance and infertility. In women, estradiol is not only critical for reproductive function, but they also control food intake and energy expenditure. Food intake is known to change during the menstrual cycle in humans. This change in food intake is largely mediated by estradiol, which acts directly upon anorexigenic and orexigenic neurons, largely in the hypothalamus. Estradiol also acts indirectly with peripheral mediators such as glucagon like peptide-1 (GLP-1). Like estradiol, GLP-1 acts on receptors at the hypothalamus. This review describes the physiological and pathophysiological mechanisms governing the actions of estradiol during the menstrual cycle on food intake and energy expenditure and how estradiol acts with other weight-controlling molecules such as GLP-1. GLP-1 analogs have proven to be effective both to manage obesity and T2D in women. This review also highlights the relationship between steroid hormones and women's mental health. It explains how a decline or imbalance in estradiol levels affects insulin sensitivity in the brain. This can cause cerebral insulin resistance, which contributes to the development of conditions such as Parkinson's or Alzheimer's disease. The proper use of both estradiol and GLP-1 analogs can help to manage obesity and preserve an optimal mental health in women by reducing the mechanisms that trigger neurodegenerative disorders.
    MeSH term(s) Humans ; Female ; Estradiol ; Insulin Resistance ; Diabetes Mellitus, Type 2 ; Glucagon-Like Peptide 1 ; Obesity ; Drug-Related Side Effects and Adverse Reactions
    Chemical Substances Estradiol (4TI98Z838E) ; Glucagon-Like Peptide 1 (89750-14-1)
    Language English
    Publishing date 2022-11-07
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2022.951186
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  10. Article ; Online: Universal interface fluctuations in the contact process.

    Barreales, B G / Meléndez, J J / Cuerno, R / Ruiz-Lorenzo, J J

    Physical review. E

    2023  Volume 108, Issue 4-1, Page(s) 44801

    Abstract: We study the interface representation of the contact process at its directed-percolation critical point, where the scaling properties of the interface can be related to those of the original particle model. Interestingly, such a behavior happens to be ... ...

    Abstract We study the interface representation of the contact process at its directed-percolation critical point, where the scaling properties of the interface can be related to those of the original particle model. Interestingly, such a behavior happens to be intrinsically anomalous and more complex than that described by the standard Family-Vicsek dynamic scaling Ansatz of surface kinetic roughening. We expand on a previous numerical study by Dickman and Muñoz [Phys. Rev. E 62, 7632 (2000)10.1103/PhysRevE.62.7632] to fully characterize the kinetic roughening universality class for interface dimensions d=1,2, and 3. Beyond obtaining scaling exponent values, we characterize the interface fluctuations via their probability density function (PDF) and covariance, seen to display universal properties which are qualitatively similar to those recently assessed for the Kardar-Parisi-Zhang (KPZ) and other important universality classes of kinetic roughening. Quantitatively, while for d=1 the interface covariance seems to be well described by the KPZ, Airy_{1} covariance, no such agreement occurs in terms of the fluctuation PDF or the scaling exponents.
    Language English
    Publishing date 2023-11-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2844562-4
    ISSN 2470-0053 ; 2470-0045
    ISSN (online) 2470-0053
    ISSN 2470-0045
    DOI 10.1103/PhysRevE.108.044801
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