LIVIVO - Search results -

Search results

Result 1 - 10 of total 59

Search options

Article ; Online: Combined in vitro/in silico approaches, molecular dynamics simulations and safety assessment of the multifunctional properties of thymol and carvacrol: A comparative insight.

Akermi, Sarra / Smaoui, Slim / Chaari, Moufida / Elhadef, Khaoula / Gentile, Rocco / Hait, Milan / Roymahapatra, Gourisankar / Mellouli, Lotfi

Chemistry & biodiversity

2024 Volume 21, Issue 2, Page(s) e202301575

Abstract: Bioactive compounds derived from medicinal plants have acquired immense attentiveness in drug discovery and development. The present study investigated in vitro and predicted in silico the antibacterial, antifungal, and antiviral properties of thymol and ...

Abstract	Bioactive compounds derived from medicinal plants have acquired immense attentiveness in drug discovery and development. The present study investigated in vitro and predicted in silico the antibacterial, antifungal, and antiviral properties of thymol and carvacrol, and assessed their safety. The performed microbiological assays against Pseudomonas aeruginosa, Escherichia coli, Salmonella enterica Typhimurium revealed that the minimal inhibitory concentration values ranged from (0.078 to 0.312 mg/mL) and the minimal fungicidal concentration against Candida albicans was 0.625 mg/mL. Molecular docking simulations, stipulated that these compounds could inhibit bacterial replication and transcription functions by targeting DNA and RNA polymerases receptors with docking scores varying between (-5.1 to -6.9 kcal/mol). Studied hydroxylated monoterpenes could hinder C. albicans growth by impeding lanosterol 14α-demethylase enzyme and showed a (ΔG=-6.2 and -6.3 kcal/mol). Computational studies revealed that thymol and carvacrol could target the SARS-Cov-2 spike protein of the Omicron variant RBD domain. Molecular dynamics simulations disclosed that these compounds have a stable dynamic behavior over 100 ns as compared to remdesivir. Chemo-computational toxicity prediction using Protox II webserver indicated that thymol and carvacrol could be safely and effectively used as drug candidates to tackle bacterial, fungal, and viral infections as compared to chemical medication.
MeSH term(s)	Humans ; Thymol/pharmacology ; Thymol/metabolism ; Molecular Dynamics Simulation ; Molecular Docking Simulation ; Monoterpenes/pharmacology ; Monoterpenes/metabolism ; Salmonella typhimurium ; Candida albicans ; Escherichia coli ; Cymenes ; Spike Glycoprotein, Coronavirus
Chemical Substances	Thymol (3J50XA376E) ; carvacrol (9B1J4V995Q) ; spike protein, SARS-CoV-2 ; Monoterpenes ; Cymenes ; Spike Glycoprotein, Coronavirus
Language	English
Publishing date	2024-01-15
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2139001-0
ISSN	1612-1880 ; 1612-1872
ISSN (online)	1612-1880
ISSN	1612-1872
DOI	10.1002/cbdv.202301575
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article: Disclosing the Functional Potency of Three Oxygenated Monoterpenes in Combating Microbial Pathogenesis: From Targeting Virulence Factors to Chicken Meat Preservation.

Akermi, Sarra / Chaari, Moufida / Elhadef, Khaoula / Fourati, Mariam / Chakchouk Mtibaa, Ahlem / Agriopoulou, Sofia / Smaoui, Slim / Mellouli, Lotfi

Foods (Basel, Switzerland)

2024 Volume 13, Issue 6

Abstract: During the last few decades, there has existed an increased interest in and considerable consumer preference towards using natural and safe compounds derived from medicinal plants as alternatives to synthetic preservatives to combat microbial ... ...

Abstract	During the last few decades, there has existed an increased interest in and considerable consumer preference towards using natural and safe compounds derived from medicinal plants as alternatives to synthetic preservatives to combat microbial pathogenicity. In this regard, the present study investigated the possible synergistic interactions of the anti-foodborne bacterial capacity of linalool (L), eucalyptol (E), and camphor (C). The antibacterial synergistic effect was determined against
Language	English
Publishing date	2024-03-21
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2704223-6
ISSN	2304-8158
ISSN	2304-8158
DOI	10.3390/foods13060965
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Total Polyphenol, Flavonoid, and Proanthocyanidin Contents and Biological Activities of Inula Graveolens Collected from Chebba (Tunisia) Salt Marsh

Sellem, Imen / Chakchouk-Mtibaa, Ahlem / Smaoui, Slim / Mellouli, Lotfi

Journal of herbs, spices & medicinal plants. 2021 Oct. 02, v. 27, no. 4

2021

Abstract: The biological activities of Inula graveolens in Chebba (Tunisia) salt marsh were screened. Total polyphenol (TPP), flavonoid (TF), and proanthocyanidin (TPC) contents were determined and the correlation between the phytochemistry and the antioxidant, ... ...

Abstract	The biological activities of Inula graveolens in Chebba (Tunisia) salt marsh were screened. Total polyphenol (TPP), flavonoid (TF), and proanthocyanidin (TPC) contents were determined and the correlation between the phytochemistry and the antioxidant, antimicrobial, and anti-enzymatic activities was assessed. The polyphenols in the solvent extracts suggested that salinity stress may enhance the production of bioactive compounds. Antiradical activities and a potent acetylcholinesterase inhibitory power were observed. I. graveolens extracts were antimicrobial against Salmonella typhimurium, Micrococcus luteus, and Staphylococcus aureus. Total flavonoids correlated with the activity against M. luteus, while the total polyphenols content was not correlated with the antimicrobial activity.
Keywords	Dittrichia graveolens ; Micrococcus luteus ; Salmonella Typhimurium ; Staphylococcus aureus ; acetylcholinesterase ; antimicrobial properties ; antioxidants ; flavonoids ; proanthocyanidins ; salt marshes ; salt stress ; solvents ; Tunisia
Language	English
Dates of publication	2021-1002
Size	p. 426-444.
Publishing place	Taylor & Francis
Document type	Article
ZDB-ID	1122804-0
ISSN	1540-3580 ; 1049-6475
ISSN (online)	1540-3580
ISSN	1049-6475
DOI	10.1080/10496475.2021.1947928
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Cologne/Königswinter

Zs.A 3868: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Chemometric Multivariate Analyses of Kernel Biometric Techniques and Shell Morphological Attributes for Analyzing Pistacia vera L. Genotypes Variability

Ennouri, Karim / Smaoui, Slim / Ben Hlima, Hajer / Ben Ayed, Rayda / Ben Braiek, Olfa / Mellouli, Lotfi / Triki, Mohamed Ali

Erwerbsobstbau. 2022 June, v. 64, no. 2

2022

Abstract: In this study, the corresponding correlations, interdependencies, and relationships of nine traits of pistachio (Pistacia vera L.) kernels were established. Here, the percentage of dehiscent shells, shell homogeneity, shell apex, position of suture ... ...

Title translation	Chemometrische multivariate Analysen von biometrischen Eigenschaften des Kerns und morphologischen Attributen der Schale zur Bestimmung der Variabilität von Genotypen bei Pistacia vera L.
Abstract	In this study, the corresponding correlations, interdependencies, and relationships of nine traits of pistachio (Pistacia vera L.) kernels were established. Here, the percentage of dehiscent shells, shell homogeneity, shell apex, position of suture opening, suture opening, number of pistachio kernels/100 g, (length/width) pistachio kernel ratio, pistachio kernel flavour and fat content of pistachio kernel were studied.The evaluation of experimental data was performed by applying a chemometric approach: Principal Component Analysis (PCA), Bayesian Networks method and Network Meta-Analysis. In this regard, based on PCA the first principal component of shell and kernel had high loadings for shell homogeneity. By using Bayesian Networks method, dendrogram of selected pistachio varieties demonstrate a high similitude existing between varieties. Furthermore, the of shell and kernel dendrogram of studied pistachio varieties demonstrated that all studied accessions could be separated into four distinct groups. Based on cluster analysis, a detailed comparison between the varieties demonstrated that the accession named ‘KERMAN’ showed a significant similarity with the Tunisian genotype ‘ELGUETAR’. In this line, Network Meta-Analysis exhibited the different interdependencies between morphological parameters, and the hierarchical clustering via heat maps displayed relationships between studied factors.These results showed a potential use of desired characteristics at least in some infra-specific studies in Pistacia vera L. The findings of this study will help plant growers by highlighting hidden and eventual relationships between Pistacia vera L. varieties.
Keywords	Bayesian theory ; Pistacia vera ; biometry ; chemometrics ; cluster analysis ; flavor ; genotype ; heat ; lipid content ; meta-analysis ; pistachios ; principal component analysis
Language	English
Dates of publication	2022-06
Size	p. 283-290.
Publishing place	Springer Berlin Heidelberg
Document type	Article
ZDB-ID	519117-8
ISSN	1439-0302 ; 0014-0309
ISSN (online)	1439-0302
ISSN	0014-0309
DOI	10.1007/s10341-021-00635-w
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

Z 1227: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: In-Depth Study of

Akermi, Sarra / Smaoui, Slim / Fourati, Mariam / Elhadef, Khaoula / Chaari, Moufida / Chakchouk Mtibaa, Ahlem / Mellouli, Lotfi

BioMed research international

2022 Volume 2022, Page(s) 3368883

Abstract: Questions have been raised apropos the emerging problem of microbial resistance, which may pose a great hazard to the human health. Among biosafe compounds are essential oils which captured consumer draw due to their multifunctional properties compared ... ...

Abstract	Questions have been raised apropos the emerging problem of microbial resistance, which may pose a great hazard to the human health. Among biosafe compounds are essential oils which captured consumer draw due to their multifunctional properties compared to chemical medication drugs. Here, we examined the chemical profile and the mechanism(s) of action of the
MeSH term(s)	Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Humans ; Listeria monocytogenes ; Microbial Sensitivity Tests ; Molecular Docking Simulation ; Oils, Volatile/chemistry ; Oils, Volatile/pharmacology ; Staphylococcus aureus ; Thymol/pharmacology ; Thymus Plant/chemistry
Chemical Substances	Anti-Bacterial Agents ; Oils, Volatile ; Thymol (3J50XA376E)
Language	English
Publishing date	2022-07-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	2698540-8
ISSN	2314-6141 ; 2314-6133
ISSN (online)	2314-6141
ISSN	2314-6133
DOI	10.1155/2022/3368883
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Variability in Phytochemical Contents and Biological Potential of Pomegranate (Punica granatum) Peel Extracts: Toward a New Opportunity for Minced Beef Meat Preservation

Fourati, Mariam / Smaoui, Slim / Ben Hlima, Hajer / Elhadef, Khaoula / Chakchouk Mtibaa, Ahlem / Mellouli, Lotfi

Journal of food quality. 2020 Sept. 30, v. 2020

2020

Abstract: Extraction of Tunisian pomegranate peels was employed with different solvents such as ethyl acetate, acetonitrile, and water. Total phenolic and flavonoids contents, antioxidant activity, and antibacterial capacity against five foodborne pathogenic ... ...

Abstract	Extraction of Tunisian pomegranate peels was employed with different solvents such as ethyl acetate, acetonitrile, and water. Total phenolic and flavonoids contents, antioxidant activity, and antibacterial capacity against five foodborne pathogenic bacteria were evaluated. The highest values of polyphenols (351 mg gallic acid equivalent/g), flavonoids (104 mg quercetin/g), and DPPH and ABTS inhibition were recorded in the ethyl acetate extract followed by the aqueous extract. The latter present the maximum antibacterial potential against S. enterica, P. aeruginosa, and E. coli. The potential use of the lyophilized aqueous extract (AE), used for safety reason and being rich in phenolic, as biopreservative in minced beef meat was described. AE was incorporated at 0.1, 0.5, and 1% and compared with 0.1% butylated hydroxytoluene (BHT). During 21 days at 4°C, AE at 1% could appreciably retard the microflora proliferation (p<0.05), the accumulation of MetMb and the carbonyl group (p<0.05), slowing down the loss of sulphydryl proteins (p<0.05), and led to a decrease (p<0.05) in primary (peroxide value and conjugated dienes) and secondary lipid oxidation (TBARS) in treated meat. By the 14ᵗʰ day, AE-treated minced meat obtained higher sensory scores than untreated and BHT samples. Based on these results, lipid and protein oxidation changes and sensorial attributes were useful in discriminating meat samples by overall acceptability prediction. Generally, AE at 1% presented the potent preservative effect that could be utilized as an application on meat-substituting synthetic antioxidant.
Keywords	Escherichia coli ; Punica granatum ; acetonitrile ; antibacterial properties ; antioxidant activity ; antioxidants ; butylated hydroxytoluene ; ethyl acetate ; food quality ; freeze drying ; gallic acid ; lipid peroxidation ; lipids ; microorganisms ; minced beef ; oxidation ; peroxide value ; polyphenols ; pomegranates ; prediction ; quercetin
Language	English
Dates of publication	2020-0930
Publishing place	Hindawi
Document type	Article
Note	NAL-AP-2-clean
ZDB-ID	2175284-9
ISSN	1745-4557 ; 0146-9428
ISSN (online)	1745-4557
ISSN	0146-9428
DOI	10.1155/2020/8853196
Database	NAL-Catalogue (AGRICOLA)

Order via subito

Article: Recent advancements in encapsulation of bioactive compounds as a promising technique for meat preservation

Smaoui, Slim / Ben Hlima, Hajer / Ben Braïek, Olfa / Ennouri, Karim / Mellouli, Lotfi / Mousavi Khaneghah, Amin

Meat science. 2021 Nov., v. 181

2021

Abstract: Encapsulation is currently considered as one the most valuable methods for preserving aromatic compounds or hiding odors, enhancing their thermal and oxidative stability, and expanding their food applications. Indeed, this current article was aimed to ... ...

Abstract	Encapsulation is currently considered as one the most valuable methods for preserving aromatic compounds or hiding odors, enhancing their thermal and oxidative stability, and expanding their food applications. Indeed, this current article was aimed to provide an overview regarding the encapsulation of plant bioactive compounds and the spray-drying and extrusion processes with a focused discussion regarding the encountered challenges for meat and meat product preservation. Furthermore, different ranges of carbohydrates as wall materials (carriers) besides the process conditions' effects on the encapsulation effectiveness and the particle size of the encapsulated bioactive compounds have been discussed. The encapsulation of these compounds ameliorates the quality of the stored meat products by further delaying in microflora growth and lipid/protein oxidation. Therefore, the innovative technologies for plant active compounds encapsulation offer a prospective alternative for natural preservation development in the meat industry.
Keywords	encapsulation ; extrusion ; lipids ; livestock and meat industry ; meat ; meat science ; microorganisms ; oxidation ; oxidative stability ; particle size ; spray drying
Language	English
Dates of publication	2021-11
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	753319-6
ISSN	1873-4138 ; 0309-1740
ISSN (online)	1873-4138
ISSN	0309-1740
DOI	10.1016/j.meatsci.2021.108585
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

Z 4037: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article: Application of essential oils in meat packaging: A systemic review of recent literature

Smaoui, Slim / Ben Hlima, Hajer / Tavares, Loleny / Ennouri, Karim / Ben Braiek, Olfa / Mellouli, Lotfi / Abdelkafi, Slim / Mousavi Khaneghah, Amin

Food control. 2022 Feb., v. 132

2022

Abstract: During preparation, processing, and distribution, the spoilage of meat products has been causing a negative economic impact in the meat industries. In addition, lipid/protein oxidation and deterioration resulting from microorganisms' development are ... ...

Abstract	During preparation, processing, and distribution, the spoilage of meat products has been causing a negative economic impact in the meat industries. In addition, lipid/protein oxidation and deterioration resulting from microorganisms' development are other concerns verified during the storage of meat and meat derivatives. In this sense, the meat industry has designed biopolymers-based materials containing biomolecules as active packaging to diminish losses and improve the shelf-life of these products. Here, we examined the loading of essential oils in the active films and coatings. Their impact on the chemico–physio–mechanico properties and antioxidant and antibacterial potential of the numerous biopolymer films for packaging meat and derived products are discussed. The potential use of essential oils incorporated into biopolymer network matrices of these films was also evaluated. This review also covers the biological effects of different types of edible films and the influence of these functional packaging on improving meat product quality. Interestingly, active films containing essential oil present a future approach and an environmentally friendly solution in the meat industry. In general, active food packaging revealed suitable technology to improve meat quality and reduce waste in the food industry.
Keywords	antibacterial properties ; antioxidants ; biopolymers ; economic impact ; essential oils ; food industry ; food safety ; lipids ; livestock and meat industry ; meat ; meat quality ; oxidation ; shelf life ; spoilage ; wastes
Language	English
Dates of publication	2022-02
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	1027805-9
ISSN	0956-7135
ISSN	0956-7135
DOI	10.1016/j.foodcont.2021.108566
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

Z 5255: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: A New Endophytic Fusarium Oxysporum Gibberellic Acid: Optimization of Production Using Combined Strategies of Experimental Designs and Potency on Tomato Growth under Stress Condition.

Ben Rhouma, Marwa / Kriaa, Mouna / Ben Nasr, Yosri / Mellouli, Lotfi / Kammoun, Radhouane

BioMed research international

2020 Volume 2020, Page(s) 4587148

Abstract: This study reports the potential of the endophytic fungi identified as ... ...

Abstract	This study reports the potential of the endophytic fungi identified as a
MeSH term(s)	Chlorophyll/metabolism ; Chromatography, High Pressure Liquid ; Fermentation/drug effects ; Fusarium/chemistry ; Fusarium/growth & development ; Fusarium/metabolism ; Gibberellins/chemistry ; Gibberellins/isolation & purification ; Gibberellins/pharmacology ; Lycopersicon esculentum/drug effects ; Lycopersicon esculentum/growth & development ; Plant Growth Regulators/biosynthesis ; Plant Growth Regulators/isolation & purification ; Salinity ; Stress, Physiological/drug effects
Chemical Substances	Gibberellins ; Plant Growth Regulators ; Chlorophyll (1406-65-1) ; gibberellic acid (BU0A7MWB6L)
Language	English
Publishing date	2020-03-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	2698540-8
ISSN	2314-6141 ; 2314-6133
ISSN (online)	2314-6141
ISSN	2314-6133
DOI	10.1155/2020/4587148
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Recent advancements in encapsulation of bioactive compounds as a promising technique for meat preservation.

Smaoui, Slim / Ben Hlima, Hajer / Ben Braïek, Olfa / Ennouri, Karim / Mellouli, Lotfi / Mousavi Khaneghah, Amin

Meat science

2021 Volume 181, Page(s) 108585

Abstract	Encapsulation is currently considered as one the most valuable methods for preserving aromatic compounds or hiding odors, enhancing their thermal and oxidative stability, and expanding their food applications. Indeed, this current article was aimed to provide an overview regarding the encapsulation of plant bioactive compounds and the spray-drying and extrusion processes with a focused discussion regarding the encountered challenges for meat and meat product preservation. Furthermore, different ranges of carbohydrates as wall materials (carriers) besides the process conditions' effects on the encapsulation effectiveness and the particle size of the encapsulated bioactive compounds have been discussed. The encapsulation of these compounds ameliorates the quality of the stored meat products by further delaying in microflora growth and lipid/protein oxidation. Therefore, the innovative technologies for plant active compounds encapsulation offer a prospective alternative for natural preservation development in the meat industry.
MeSH term(s)	Food Preservation/methods ; Meat/analysis ; Meat/microbiology ; Meat Products/analysis ; Meat Products/microbiology ; Oxidation-Reduction ; Particle Size ; Phytochemicals
Chemical Substances	Phytochemicals
Language	English
Publishing date	2021-05-29
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	753319-6
ISSN	1873-4138 ; 0309-1740
ISSN (online)	1873-4138
ISSN	0309-1740
DOI	10.1016/j.meatsci.2021.108585
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Bonn / Germany

Z 4037: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED