Article ; Online: Optimizing
Cardiovascular and interventional radiology
2022 Volume 45, Issue 7, Page(s) 958–969
Abstract: Purpose: To determine how particle density affects dose distribution and outcomes after lobar radioembolization.: Methods: Matched pairs of patients, treated with glass versus resin microspheres, were selected by propensity score matching (114 ... ...
| Abstract | Purpose: To determine how particle density affects dose distribution and outcomes after lobar radioembolization. Methods: Matched pairs of patients, treated with glass versus resin microspheres, were selected by propensity score matching (114 patients), in this single-institution retrospective study. For each patient, tumor and liver particle density (particles/cm Results: As more particles were delivered, doses on Conclusion: The number of particles delivered can be chosen to maximize the tumor dose and minimize the liver dose, based on tumor vascularity. Optimizing the particle density resulted in improved LPFS and overall survival. |
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| MeSH term(s) | Carcinoma, Hepatocellular/diagnostic imaging ; Carcinoma, Hepatocellular/radiotherapy ; Embolization, Therapeutic/methods ; Humans ; Liver Neoplasms/diagnostic imaging ; Liver Neoplasms/radiotherapy ; Microspheres ; Retrospective Studies ; Technetium Tc 99m Aggregated Albumin ; Tomography, Emission-Computed, Single-Photon ; Yttrium Radioisotopes/therapeutic use |
| Chemical Substances | Technetium Tc 99m Aggregated Albumin ; Yttrium Radioisotopes |
| Language | English |
| Publishing date | 2022-04-22 |
| Publishing country | United States |
| Document type | Journal Article |
| ZDB-ID | 603082-8 |
| ISSN | 1432-086X ; 0342-7196 ; 0174-1551 |
| ISSN (online) | 1432-086X |
| ISSN | 0342-7196 ; 0174-1551 |
| DOI | 10.1007/s00270-022-03139-6 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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