LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 5 of total 5

Search options

  1. Article ; Online: Vitamin K

    Xu, Wencheng / Meng, Kehan / Wu, Hongguang / Miura, Taro / Suzuki, Shunsuke / Chiyotanda, Masako / Tanaka, Sachiko / Sugiyama, Kentaro / Kawashima, Hisashi / Hirano, Toshihiko

    Pediatrics international : official journal of the Japan Pediatric Society

    2019  Volume 61, Issue 12, Page(s) 1188–1195

    Abstract: Background: Over 20 kinds of steroids, tacrolimus ointments, and cyclosporine capsules are usually recommended for the treatment of atopic dermatitis (AD), depending on the symptoms of patients. However, several side effects sometimes occur with the ... ...

    Abstract Background: Over 20 kinds of steroids, tacrolimus ointments, and cyclosporine capsules are usually recommended for the treatment of atopic dermatitis (AD), depending on the symptoms of patients. However, several side effects sometimes occur with the extensive use of these agents for the treatment of pediatric AD patients. The purpose of this study was to explore whether vitamin K
    Methods: The immunosuppressive efficacy of vitamin K
    Results: The mean (SD) IC
    Conclusion: Vitamin K
    MeSH term(s) Adult ; Cell Proliferation/drug effects ; Cells, Cultured ; Child ; Child, Preschool ; Cyclosporine/pharmacology ; Dermatitis, Atopic/drug therapy ; Female ; Healthy Volunteers ; Humans ; Immunosuppressive Agents/administration & dosage ; Immunosuppressive Agents/pharmacology ; Leukocytes, Mononuclear/drug effects ; Male ; Methylprednisolone/pharmacology ; Tacrolimus/pharmacology ; Vitamin K 2/administration & dosage ; Vitamin K 2/pharmacology ; Vitamin K 2/therapeutic use
    Chemical Substances Immunosuppressive Agents ; Vitamin K 2 (11032-49-8) ; Cyclosporine (83HN0GTJ6D) ; Tacrolimus (WM0HAQ4WNM) ; Methylprednisolone (X4W7ZR7023)
    Language English
    Publishing date 2019-12-13
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 1470376-2
    ISSN 1442-200X ; 1328-8067
    ISSN (online) 1442-200X
    ISSN 1328-8067
    DOI 10.1111/ped.14014
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 848: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: The effects of vitamin K1 and vitamin K2 on the proliferation, cytokine production and regulatory T-cell frequency in peripheral blood mononuclear cells of paediatric atopic dermatitis patients.

    Meng, Kehan / Xu, Wencheng / Miura, Taro / Suzuki, Shunsuke / Chiyotanda, Masako / Tanaka, Sachiko / Sugiyama, Kentaro / Kawashima, Hisashi / Hirano, Toshihiko

    Experimental dermatology

    2018  Volume 27, Issue 9, Page(s) 1058–1060

    Abstract: We estimated the pharmacological efficacy of vitamin ... ...

    Abstract We estimated the pharmacological efficacy of vitamin K
    MeSH term(s) CD4 Lymphocyte Count ; Cell Proliferation/drug effects ; Cells, Cultured ; Child ; Concanavalin A/pharmacology ; Dermatitis, Atopic/blood ; Dermatitis, Atopic/immunology ; Dermatitis, Atopic/pathology ; Humans ; Interleukin-10/metabolism ; Interleukin-2/metabolism ; Leukocytes, Mononuclear/physiology ; Mitogens/pharmacology ; T-Lymphocytes, Regulatory/pathology ; Vitamin K 1/pharmacology ; Vitamin K 2/pharmacology ; Vitamins/pharmacology
    Chemical Substances IL10 protein, human ; IL2 protein, human ; Interleukin-2 ; Mitogens ; Vitamins ; Concanavalin A (11028-71-0) ; Vitamin K 2 (11032-49-8) ; Interleukin-10 (130068-27-8) ; Vitamin K 1 (84-80-0)
    Language English
    Publishing date 2018-08-03
    Publishing country Denmark
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1130936-2
    ISSN 1600-0625 ; 0906-6705
    ISSN (online) 1600-0625
    ISSN 0906-6705
    DOI 10.1111/exd.13671
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 3508: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article: Simultaneous Determination of Rutin, Luteolin, Quercetin, and Betulinic Acid in the Extract of Disporopsis pernyi (Hua) Diels by UPLC.

    Wang, Yanqi / Li, Shuyi / Han, Dandan / Meng, Kehan / Wang, Miao / Zhao, Chunjie

    Journal of analytical methods in chemistry

    2015  Volume 2015, Page(s) 130873

    Abstract: Disporopsis pernyi (Hua) Diels, which belongs to genus Disporopsis, has been widely used for the treatment of abnormal sweating, chronic cough, and so forth. An ultra-performance liquid chromatography (UPLC) analysis was developed for the determination ... ...

    Abstract Disporopsis pernyi (Hua) Diels, which belongs to genus Disporopsis, has been widely used for the treatment of abnormal sweating, chronic cough, and so forth. An ultra-performance liquid chromatography (UPLC) analysis was developed for the determination of rutin, luteolin, quercetin, and betulinic acid in Disporopsis pernyi (Hua) Diels roots. UPLC analysis was conducted by using a Shim-pack XR-ODS column with gradient elution with the mobile phase of acetonitrile and water containing 0.1% formic acid and with a flow rate of 0.2 mL/min, detected at 210, 254, and 280 nm. The method was precise, with relative standard deviation < 2.0%. The recoveries for the four components in Disporopsis pernyi (Hua) Diels were between 98.5 and 100.9%. The average contents of rutin, luteolin, quercetin, and betulinic acid in roots were 5.63, 2.51, 3.87, and 2.41 μg/g, respectively. The method was accurate and reproducible and it can provide a quantitative basis for quality control of Disporopsis pernyi (Hua) Diels.
    Language English
    Publishing date 2015-12-22
    Publishing country Egypt
    Document type Journal Article
    ZDB-ID 2654178-6
    ISSN 2090-8873 ; 2090-8865
    ISSN (online) 2090-8873
    ISSN 2090-8865
    DOI 10.1155/2015/130873
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Tetrandrine potentiates the glucocorticoid pharmacodynamics via inhibiting P-glycoprotein and mitogen-activated protein kinase in mitogen-activated human peripheral blood mononuclear cells.

    Xu, Wencheng / Meng, Kehan / Tu, Yuanchao / Tanaka, Sachiko / Onda, Kenji / Sugiyama, Kentaro / Hirano, Toshihiko / Yamada, Haruki

    European journal of pharmacology

    2017  Volume 807, Page(s) 102–108

    Abstract: Glucocorticoids play significant roles in treatments of inflammatory and autoimmune diseases. Some patients show a poor or absent response even to high doses of glucocorticoids. The purpose of this study was to explore whether tetrandrine combined with ... ...

    Abstract Glucocorticoids play significant roles in treatments of inflammatory and autoimmune diseases. Some patients show a poor or absent response even to high doses of glucocorticoids. The purpose of this study was to explore whether tetrandrine combined with glucocorticoids could be a new treatment strategy to resolve glucocorticoids resistance. Information on glucocorticoids sensitivity was usually obtained through mitogen-activated human peripheral blood mononuclear cells in cell culture procedures. Thus, human peripheral blood mononuclear cells was chosen as a model to study the immunosuppressive effect of methylprednisolone combined with tetrandrine, including the possible action mechanisms. Tetrandrine decreased the IC
    Language English
    Publishing date 2017-07-15
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 80121-5
    ISSN 1879-0712 ; 0014-2999
    ISSN (online) 1879-0712
    ISSN 0014-2999
    DOI 10.1016/j.ejphar.2017.04.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 522: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Immunosuppressive efficacy of tetrandrine combined with methylprednisolone against mitogen-activated peripheral blood mononuclear cells of haemodialysis patients.

    Xu, Wencheng / Meng, Kehan / Kusano, Junichi / Matsuda, Hiroto / Hara, Yoshikazu / Fujii, Yoshiaki / Suzuki, Shinya / Ando, Eiki / Wang, Xiaoqin / Tu, Yuanchao / Tanaka, Sachiko / Sugiyama, Kentaro / Yamada, Haruki / Hirano, Toshihiko

    Clinical and experimental pharmacology & physiology

    2017  Volume 44, Issue 9, Page(s) 924–931

    Abstract: Immunosuppressive therapy for prevention of acute rejection episode occasionally causes serious adverse effects, and thus it is important to develop new therapeutic approach for renal transplant recipients. This study evaluated the immunosuppressive ... ...

    Abstract Immunosuppressive therapy for prevention of acute rejection episode occasionally causes serious adverse effects, and thus it is important to develop new therapeutic approach for renal transplant recipients. This study evaluated the immunosuppressive pharmacodynamics of tetrandrine (TET) and/or methylprednisolone (MP) in haemodialysis patients in vitro by using the peripheral blood mononuclear cells (PBMCs) isolated from whole blood of haemodialysis patients. The median (range) of MP IC
    Language English
    Publishing date 2017-09
    Publishing country Australia
    Document type Journal Article
    ZDB-ID 189277-0
    ISSN 1440-1681 ; 0305-1870 ; 0143-9294
    ISSN (online) 1440-1681
    ISSN 0305-1870 ; 0143-9294
    DOI 10.1111/1440-1681.12797
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 990: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top