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Article: [Reliability and validity of the Chinese version of adverse childhood experiences international questionnaire in parents of preschool children].

Mi, X Y / Hou, S S / Fu, Z Y / Zhou, M / Li, X X / Meng, Z X / Jiang, H F / Zhou, H

Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences

2023 Volume 55, Issue 3, Page(s) 408–414

Abstract: Objective: To test the reliability and validity of the Chinese version of adverse childhood experiences international questionnaire (ACE-IQ) in Chinese parents of preschool children.: Methods: The parents of preschool children in 6 kindergartens in ... ...

Abstract	Objective: To test the reliability and validity of the Chinese version of adverse childhood experiences international questionnaire (ACE-IQ) in Chinese parents of preschool children. Methods: The parents of preschool children in 6 kindergartens in Tongzhou District of Beijing were selected by stratified random cluster sampling, and the Chinese version of ACE-IQ after translation and adaptation was used for survey online. The collected data were randomly divided into two parts. One part of the data ( Results: After deleting four items of collective violence, the Chinese version of ACE-IQ with twenty-five items indicated good structural, criterion and content validity. Analysis results showed that the Chinese version of ACE-IQ presented a seven-factor model dimension, namely emotional neglect, physical neglect, family dysfunction, family violence, emotional and physical abuse, sexual abuse and violence outside the home, and the total score of the binary version of ACE-IQ Chinese version was positively correlated with the total score of childhood trauma questionaire-28 item short form (CTQ-SF, Conclusion: This study has formed a Chinese version of ACE-IQ with 25 items and 7 dimensions, which has good reliability and validity among the parents of preschool children in China. It can be used as an evaluation instrument for measuring the minimum threshold of the adverse childhood experiences in the parents of preschool children in the cultural background of China.
MeSH term(s)	Humans ; Child, Preschool ; Adverse Childhood Experiences ; Reproducibility of Results ; Parents/psychology ; Surveys and Questionnaires ; China ; Psychometrics/methods
Language	Chinese
Publishing date	2023-06-08
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	2452593-5
ISSN	1671-167X
ISSN	1671-167X
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: [Low temperature plasma minimally invasive treatment of children piriform fossa fistula].

Ji, R F / Zhao, Z L / Zhou, Q / Meng, Z X / Ji, W

Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery

2019 Volume 33, Issue 5, Page(s) 461–463

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Abscess ; Child ; Cold Temperature ; Drainage ; Fistula/surgery ; Humans ; Neck ; Plasma Gases/therapeutic use ; Pyriform Sinus/pathology ; Pyriform Sinus/surgery ; Recurrence ; Reoperation ; Treatment Outcome
Chemical Substances	Plasma Gases
Language	Chinese
Publishing date	2019-06-01
Publishing country	China
Document type	Journal Article
ISSN	1001-1781
ISSN	1001-1781
DOI	10.13201/j.issn.1001-1781.2019.05.019
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Article ; Online: Education and Imaging: Gastroenterology: Fatal abdominal compartment syndrome caused by colonic perforation in an adult with Hirschsprung's disease.

Li, T / Meng, Z-X / Zhi, X-T

Journal of gastroenterology and hepatology

2015 Volume 30, Issue 11, Page(s) 1562

MeSH term(s)	Adult ; Colonic Diseases/complications ; Colonic Diseases/diagnostic imaging ; Fatal Outcome ; Hirschsprung Disease/complications ; Hirschsprung Disease/diagnostic imaging ; Humans ; Intestinal Perforation/complications ; Intestinal Perforation/diagnostic imaging ; Intra-Abdominal Hypertension/diagnostic imaging ; Intra-Abdominal Hypertension/etiology ; Male ; Radiography, Thoracic ; Tomography, X-Ray Computed
Language	English
Publishing date	2015-11
Publishing country	Australia
Document type	Case Reports ; Journal Article
ZDB-ID	632882-9
ISSN	1440-1746 ; 0815-9319
ISSN (online)	1440-1746
ISSN	0815-9319
DOI	10.1111/jgh.13003
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Zs.A 2180: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Fabrication of mineralized electrospun PLGA and PLGA/gelatin nanofibers and their potential in bone tissue engineering.

Meng, Z X / Li, H F / Sun, Z Z / Zheng, W / Zheng, Y F

Materials science & engineering. C, Materials for biological applications

2013 Volume 33, Issue 2, Page(s) 699–706

Abstract: Surface mineralization is an effective method to produce calcium phosphate apatite coating on the surface of bone tissue scaffold which could create an osteophilic environment similar to the natural extracellular matrix for bone cells. In this study, we ... ...

Abstract	Surface mineralization is an effective method to produce calcium phosphate apatite coating on the surface of bone tissue scaffold which could create an osteophilic environment similar to the natural extracellular matrix for bone cells. In this study, we prepared mineralized poly(D,L-lactide-co-glycolide) (PLGA) and PLGA/gelatin electrospun nanofibers via depositing calcium phosphate apatite coating on the surface of these nanofibers to fabricate bone tissue engineering scaffolds by concentrated simulated body fluid method, supersaturated calcification solution method and alternate soaking method. The apatite products were characterized by the scanning electron microscopy (SEM), Fourier transform-infrared spectroscopy (FT-IR), and X-ray diffractometry (XRD) methods. A large amount of calcium phosphate apatite composed of dicalcium phosphate dihydrate (DCPD), hydroxyapatite (HA) and octacalcium phosphate (OCP) was deposited on the surface of resulting nanofibers in short times via three mineralizing methods. A larger amount of calcium phosphate was deposited on the surface of PLGA/gelatin nanofibers rather than PLGA nanofibers because gelatin acted as nucleation center for the formation of calcium phosphate. The cell culture experiments revealed that the difference of morphology and components of calcium phosphate apatite did not show much influence on the cell adhesion, proliferation and activity.
MeSH term(s)	Bone and Bones/cytology ; Calcium Phosphates/chemistry ; Cell Adhesion/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Gelatin/chemistry ; Gelatin/pharmacology ; Humans ; Lactic Acid/chemistry ; Lactic Acid/pharmacology ; Nanofibers/chemistry ; Nanotechnology/methods ; Polyglycolic Acid/chemistry ; Polyglycolic Acid/pharmacology ; Tissue Engineering/methods ; Tissue Scaffolds/chemistry
Chemical Substances	Calcium Phosphates ; polylactic acid-polyglycolic acid copolymer ; Polyglycolic Acid (26009-03-0) ; Lactic Acid (33X04XA5AT) ; Gelatin (9000-70-8) ; calcium phosphate (97Z1WI3NDX)
Language	English
Publishing date	2013-03-01
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2012160-X
ISSN	1873-0191 ; 0928-4931
ISSN (online)	1873-0191
ISSN	0928-4931
DOI	10.1016/j.msec.2012.10.021
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Article: [99mTc-MDP bolus in the treatment of bone metastasis].

Meng, Z X

Zhonghua zhong liu za zhi [Chinese journal of oncology

1990 Volume 12, Issue 2, Page(s) 135–137

Abstract: From November 1988 to March 1989, 20 patients with serious multiple bone metastases were treated by high dose 99mTc-MDP bolus. In the adult, 99mTc-MDP at a dose of 200-300 mCi was injected intravenously and repeated at 24-48 hour intervals as a course. ... ...

Abstract	From November 1988 to March 1989, 20 patients with serious multiple bone metastases were treated by high dose 99mTc-MDP bolus. In the adult, 99mTc-MDP at a dose of 200-300 mCi was injected intravenously and repeated at 24-48 hour intervals as a course. The total dose was 1,200 mCi. Subjective response rate was 100% and pain was relieved within 24 hours of the treatment in 55% of patients. The average and mean remission period was 60 days and 61 days, respectively. At least 50% of the treated patients did not require further analgesic treatment any more. Scintillation count rate ratio of the bone lesion to control was reduced by 32.13% after treatment. Repair of the destroyed bone was shown by X-ray films in some cases. No toxicity to the liver, kidney or marrow was observed.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Bone Neoplasms/radiotherapy ; Bone Neoplasms/secondary ; Female ; Humans ; Male ; Middle Aged ; Technetium Tc 99m Medronate/therapeutic use
Chemical Substances	Technetium Tc 99m Medronate (X89XV46R07)
Language	Chinese
Publishing date	1990-03
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	603424-x
ISSN	0253-3766
ISSN	0253-3766
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Zs.MO 321: Show issues

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Article: [Clinical and histological study on breast cancer treated by preoperative mitoxantrone].

Meng, Z X

Zhonghua zhong liu za zhi [Chinese journal of oncology

1990 Volume 12, Issue 4, Page(s) 294–296

Abstract: Fifteen patients with breast cancer treated with mitoxantrone preoperatively from December 1986 to June 1983 were evaluated as to treatment validity and histological response. It was shown that the mass in the breast became reduced 7 days after the start ...

Abstract	Fifteen patients with breast cancer treated with mitoxantrone preoperatively from December 1986 to June 1983 were evaluated as to treatment validity and histological response. It was shown that the mass in the breast became reduced 7 days after the start of treatment. Intact border and halo were formed around the mass and echo level inside the focus was increased even replacing all hypoecho areas by B-ultrasound. Microscopically, cell karyopyknosis, chromosome breaking plus karyorrhexis, mitochondrial destruction, vacuolization, reactive regeneration of a few capillaries and connective tissues were observed in the resected samples. Preoperative treatment with mitoxantrone helps prevent local recurrence and metastasis after tumor resection.
MeSH term(s)	Adult ; Aged ; Breast Neoplasms/drug therapy ; Breast Neoplasms/pathology ; Breast Neoplasms/surgery ; Carcinoma/drug therapy ; Carcinoma/pathology ; Carcinoma/surgery ; Combined Modality Therapy ; Female ; Humans ; Middle Aged ; Mitoxantrone/therapeutic use
Chemical Substances	Mitoxantrone (BZ114NVM5P)
Language	Chinese
Publishing date	1990-07
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	603424-x
ISSN	0253-3766
ISSN	0253-3766
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Zs.B 2277: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
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Article: [Treatment of primary glomerular kidney diseases with cyclophosphamide combined with traditional Chinese medicine--report of 23 cases].

Meng, Z X

Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine

1983 Volume 3, Issue 6, Page(s) 341–342

MeSH term(s)	Adult ; Cyclophosphamide/administration & dosage ; Drug Therapy, Combination ; Female ; Humans ; Kidney Diseases/drug therapy ; Male ; Medicine, Chinese Traditional ; Medicine, East Asian Traditional
Chemical Substances	Cyclophosphamide (8N3DW7272P)
Language	Chinese
Publishing date	1983-11
Publishing country	China
Document type	Journal Article
ISSN	0254-9034
ISSN	0254-9034
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Article ; Online: Immobilizing natural macromolecule on PLGA electrospun nanofiber with surface entrapment and entrapment-graft techniques.

Meng, Z X / Zeng, Q T / Sun, Z Z / Xu, X X / Wang, Y S / Zheng, W / Zheng, Y F

Colloids and surfaces. B, Biointerfaces

2012 Volume 94, Page(s) 44–50

Abstract: Surface entrapment is a convenient method to immobilize the natural macromolecules on the surface of synthetic polymers. In this study, the gelatin modified and sodium alginate/gelatin modified PLGA nanofibrous membranes were fabricated via surface ... ...

Abstract	Surface entrapment is a convenient method to immobilize the natural macromolecules on the surface of synthetic polymers. In this study, the gelatin modified and sodium alginate/gelatin modified PLGA nanofibrous membranes were fabricated via surface entrapment and entrapment-graft techniques. The surface morphology of the each single modified PLGA nanofiber was as smooth as that of untreated PLGA nanofibers. The results of water angle contact measurements and tensile tests showed that the surface entrapment cannot only improve the hydrophilicity but also enhance mechanical properties of the modified nanofibrous membranes. In addition, the sodium alginate/gelatin modified electrospun PLGA nanofibrous membrane exhibited higher hydrophilicity and better biocompatibility than the simply gelatin modified PLGA nanofibrous membrane, which suggested the surface entrapment is a facile and efficient approach to surface modification for electrospun nanofibours membranes.
MeSH term(s)	Alginates/chemistry ; Biocompatible Materials/chemistry ; Electrochemical Techniques ; Gelatin/chemistry ; Glucuronic Acid/chemistry ; Hexuronic Acids/chemistry ; Hydrophobic and Hydrophilic Interactions ; Lactic Acid/chemistry ; Materials Testing ; Microscopy, Electron, Scanning ; Nanofibers/chemistry ; Nanofibers/ultrastructure ; Nanotechnology ; Polyglycolic Acid/chemistry ; Surface Properties ; Tensile Strength ; Tissue Engineering/methods
Chemical Substances	Alginates ; Biocompatible Materials ; Hexuronic Acids ; polylactic acid-polyglycolic acid copolymer ; Polyglycolic Acid (26009-03-0) ; Lactic Acid (33X04XA5AT) ; Glucuronic Acid (8A5D83Q4RW) ; alginic acid (8C3Z4148WZ) ; Gelatin (9000-70-8)
Language	English
Publishing date	2012-06-01
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1500523-9
ISSN	1873-4367 ; 0927-7765
ISSN (online)	1873-4367
ISSN	0927-7765
DOI	10.1016/j.colsurfb.2012.01.017
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Article ; Online: Aberrant activation of liver X receptors impairs pancreatic beta cell function through upregulation of sterol regulatory element-binding protein 1c in mouse islets and rodent cell lines.

Meng, Z X / Yin, Y / Lv, J H / Sha, M / Lin, Y / Gao, L / Zhu, Y X / Sun, Y J / Han, X

Diabetologia

2012 Volume 55, Issue 6, Page(s) 1733–1744

Abstract: Aims/hypothesis: Liver X receptors (LXR) are important transcriptional regulators of lipid and glucose metabolism. Our previous report demonstrated that LXR activation inhibited pancreatic beta cell proliferation through cell cycle arrest. Here we ... ...

Abstract	Aims/hypothesis: Liver X receptors (LXR) are important transcriptional regulators of lipid and glucose metabolism. Our previous report demonstrated that LXR activation inhibited pancreatic beta cell proliferation through cell cycle arrest. Here we explore the role of LXR activation in beta cell insulin secretion and the underlying mechanism that might be involved. Methods: Mouse pancreatic islets or insulin-secreting MIN6 cells were exposed to the LXR agonist, T0901317, and insulin secretion, glucose and fatty acid oxidation, and lipogenic gene expression were assessed. The unsaturated fatty acid eicosapentaenoic acid and the dominant negative sterol regulatory element binding protein 1c (SREBP1c) were used to inhibit endogenous SREBP1c and evaluate the involvement of SREBP1c in beta cell dysfunction induced by LXR activation. Results: Treatment with the LXR agonist decreased beta cell glucose sensitivity and impaired glucose-stimulated insulin secretion in vivo and in vitro. This was accompanied by derangements of beta cell glucose oxygen consumption, glucose oxidation, ATP production and intracellular voltage-gated calcium channel flux. LXR activation also regulated the expression of lipid metabolism-related genes such as Fas, Acc (also known as Acaca) and Cpt1a, and led to intracellular lipid accumulation. Further studies revealed that inhibition of SREBP1c abolished LXR activation-induced lipid accumulation and improved beta cell glucose metabolism, ATP production and insulin secretion. Conclusions/interpretation: Our data reveal that aberrant activation of LXR reproduced the phenomenon of beta cell dysfunction in the development of type 2 diabetes in vitro and in vivo. Upregulation of SREBP1c production and the lipotoxicity mediated by it played a central role in this process.
MeSH term(s)	Animals ; Blotting, Western ; Cell Line ; Cells, Cultured ; Cricetinae ; Electrophysiology ; Hydrocarbons, Fluorinated/pharmacology ; Insulin/metabolism ; Insulin Secretion ; Insulin-Secreting Cells/drug effects ; Insulin-Secreting Cells/metabolism ; Islets of Langerhans/drug effects ; Islets of Langerhans/metabolism ; Liver X Receptors ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Inbred ICR ; Orphan Nuclear Receptors/agonists ; Orphan Nuclear Receptors/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; Sterol Regulatory Element Binding Protein 1/genetics ; Sterol Regulatory Element Binding Protein 1/metabolism ; Sulfonamides/pharmacology
Chemical Substances	Hydrocarbons, Fluorinated ; Insulin ; Liver X Receptors ; Orphan Nuclear Receptors ; Sterol Regulatory Element Binding Protein 1 ; Sulfonamides ; T0901317
Language	English
Publishing date	2012-03-14
Publishing country	Germany
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1694-9
ISSN	1432-0428 ; 0012-186X
ISSN (online)	1432-0428
ISSN	0012-186X
DOI	10.1007/s00125-012-2516-2
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Article: Fabrication and characterization of elastomeric polyester/carbon nanotubes nanocomposites for biomedical application.

Meng, Z X / Zheng, W / Ding, M H / Zhou, H M / Chen, X Q / Chen, J C / Liu, M K / Zheng, Y F

Journal of nanoscience and nanotechnology

2011 Volume 11, Issue 4, Page(s) 3126–3133

Abstract: A novel biodegradable polymer elastomer nanocomposite composing of poly(1,8-octanediol-citrate) (POC) polymer matrix and carbon nanotubes (CNTs) additive was successfully fabricated and systematically investigated using Fourier transform infrared (FT-IR), ...

Abstract	A novel biodegradable polymer elastomer nanocomposite composing of poly(1,8-octanediol-citrate) (POC) polymer matrix and carbon nanotubes (CNTs) additive was successfully fabricated and systematically investigated using Fourier transform infrared (FT-IR), X-ray diffractometer (XRD), differential scanning calorimetry (DSC), tensile test, incubation and cytotoxicity tests. It was found that the addition of CNTs in POC elastomer did not result in any noticeable change in its chemical structure and the amorphous state. However, the tensile strength and elongation at break were greatly improved by the addition of CNTs in POC polymer matrix. It revealed that the swelling ratio and percentage of weight loss of POC/CNTs nanocomposite were lower, compared with the pure POC material. Moreover, the adsorption amount of bovine serum albumin (BSA) increased with an increase of the CNTs mass content in POC matrix revealing the enhanced hydrophilicity of POC/CNTs nanocomposites contributed by the carboxyl of the CNTs. Additionally, the cytotoxicity tests with L929 cell line revealed that the experimental POC/CNTs nanocomposites possessed good in vitro biocompatibility.
MeSH term(s)	Animals ; Cell Line ; Elastomers/chemistry ; Elastomers/toxicity ; Fibroblasts/drug effects ; Materials Testing ; Nanocapsules/chemistry ; Nanocapsules/toxicity ; Particle Size ; Polyesters/chemistry ; Polyesters/toxicity ; Rats ; Serum Albumin, Bovine/chemistry
Chemical Substances	Elastomers ; Nanocapsules ; Polyesters ; Serum Albumin, Bovine (27432CM55Q)
Language	English
Publishing date	2011-04-29
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1533-4880
ISSN	1533-4880
DOI	10.1166/jnn.2011.3761
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