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Article ; Online: Study on the effect of digital economy development on carbon emissions: evidence from 30 provinces in China.

Tian, Jinyu / Meng, Zhe

Environmental science and pollution research international

2023 Volume 30, Issue 60, Page(s) 126088–126103

Abstract: Currently, China is moving towards the era of the digital economy, which is gradually becoming a new engine of high-quality development. In the "double carbon" strategy context, the digital economy is characterized by low carbon emissions and high ... ...

Abstract	Currently, China is moving towards the era of the digital economy, which is gradually becoming a new engine of high-quality development. In the "double carbon" strategy context, the digital economy is characterized by low carbon emissions and high permeability, making it essential for carbon emission reduction. There needs to be more empirical research on the digital economy and carbon emissions. Given this, this study empirically examines the impact of digital economy development on carbon emissions intensity and its mechanisms in a multidimensional way based on the panel data of 30 provincial-level administrative regions in China from 2011 to 2019, utilizing a fixed-effects model, a mediated-effects model, a spatial Durbin model, and other methods. The study results show that (1) the digital economy can significantly reduce carbon emissions intensity. (2) The digital economy can indirectly affect the intensity of carbon emissions through industrial structure, energy structure, and environmental regulation. (3) The development of the local digital economy has a positive spillover effect on the carbon emissions intensity of neighbouring places. However, the overall effect is negative. This paper reveals some new features of the digital economy and carbon emissions intensity, which provides a reference for advancing the country's construction and realizing China's "double carbon" goal.
MeSH term(s)	Economic Development ; China ; Carbon ; Empirical Research ; Industry ; Carbon Dioxide
Chemical Substances	Carbon (7440-44-0) ; Carbon Dioxide (142M471B3J)
Language	English
Publishing date	2023-11-27
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-023-31019-0
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Article ; Online: A Cu hollow fiber with coaxially grown Bi nanosheet arrays as an integrated gas-penetrable electrode enables high current density and durable formate electrosynthesis.

Meng, Zhe / Wang, Fang / Zhang, Zhengguo / Min, Shixiong

Nanoscale

2024 Volume 16, Issue 5, Page(s) 2295–2302

Abstract: While high current density formate ( ... ...

Abstract	While high current density formate (HCOO
Language	English
Publishing date	2024-02-01
Publishing country	England
Document type	Journal Article
ZDB-ID	2515664-0
ISSN	2040-3372 ; 2040-3364
ISSN (online)	2040-3372
ISSN	2040-3364
DOI	10.1039/d3nr05982k
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Article ; Online: Effects of ankle-foot orthoses on gait parameters in post-stroke patients with different Brunnstrom stages of the lower limb: a single-center crossover trial.

Wu, Fangchao / Meng, Zhe / Yang, Kezhen / Li, Jianhua

European journal of medical research

2024 Volume 29, Issue 1, Page(s) 235

Abstract: Background: Ankle-foot orthoses (AFO) can improve gait posture and walking ability in post-stroke patients. However, the effect of AFO on gait parameters in post-stroke patients according to the Brunnstrom stage of stroke recovery of the lower limbs ... ...

Abstract	Background: Ankle-foot orthoses (AFO) can improve gait posture and walking ability in post-stroke patients. However, the effect of AFO on gait parameters in post-stroke patients according to the Brunnstrom stage of stroke recovery of the lower limbs remains unclear. The study aimed to investigate whether stroke patients with different Brunnstrom stages benefit from wearing AFO. Methods: Twenty-five post-stroke participants included 18 men (50 ± 13 years) and 7 women (60 ± 15 years). The patients were divided based on Brunnstrom stage III or IV of the lower limbs. All patients underwent the gait and timed up and go (TUG) test using a gait analysis system while walking barefoot or with an AFO. The spatiotemporal and asymmetric parameters were analyzed. Results: All 25 patients completed the study. Significant differences were observed between barefoot and AFO use in TUG time (P < 0.001) but not walking velocity (P > 0.05). The main effect of the swing time ratio was significant in both groups (P < 0.05); however, the main effects of stride length, stance time, and gait asymmetry ratio were nonsignificant (P > 0.05). For barefoot versus AFO, the main effects of stride length (P < 0.05) and swing time (P < 0.01) ratios were significant, whereas those of stance time and gait asymmetry ratio were nonsignificant (P > 0.05). Conclusions: Post-stroke patients with lower Brunnstrom stages benefitted more from AFO, particularly in gait asymmetry.
MeSH term(s)	Male ; Humans ; Female ; Ankle ; Foot Orthoses ; Stroke Rehabilitation ; Cross-Over Studies ; Biomechanical Phenomena ; Gait Disorders, Neurologic ; Stroke/complications ; Stroke/therapy ; Gait ; Ankle Joint
Language	English
Publishing date	2024-04-15
Publishing country	England
Document type	Journal Article
ZDB-ID	1329381-3
ISSN	2047-783X ; 0949-2321
ISSN (online)	2047-783X
ISSN	0949-2321
DOI	10.1186/s40001-024-01835-2
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Article ; Online: Time-lag effects of NDVI responses to climate change in the Yamzhog Yumco Basin, South Tibet

Meng Zhe / Xueqin Zhang

Ecological Indicators, Vol 124, Iss , Pp 107431- (2021)

2021

Abstract: Vegetation dynamics and their response to climate change is critical for determining the mechanisms of climate-derived variations in terrestrial ecosystems. Here, the Normalized Difference Vegetation Index (NDVI) and monthly temperature and precipitation ...

Abstract	Vegetation dynamics and their response to climate change is critical for determining the mechanisms of climate-derived variations in terrestrial ecosystems. Here, the Normalized Difference Vegetation Index (NDVI) and monthly temperature and precipitation data were employed to examine the spatiotemporal patterns in vegetation dynamics and investigate the time-lag effects of vegetation responses to climate variables in the Yamzhog Yumco Basin, South Tibet, during 2000–2018. The results reveal that the annual average growing season NDVI in the basin was 0.28, with lower values in the mountainous regions and higher values broadly distributed in the lake and river zones. An increasing NDVI trend was observed in nearly 62% of the total vegetation area, with significant changes observed in the western and southern boundaries of the basin. The vegetation areas in the eastern part of basin exhibited a decreasing NDVI trend. The growing season NDVI was positively correlated with temperature and precipitation, with temperature being the primary driving factor for vegetation growth across the entire basin. The cumulative temperature and precipitation of the current and previous months had the strongest impact on NDVI variations. The correlation coefficients between the NDVI, and temperature and precipitation were greater than 0.6 in approximately 72% and 60% of the vegetation area, respectively, with Lag 0–1 accounting for most of these larger correlation coefficients. Future development targets for grassland conservation projects, such as the reasonable livestock capacity, should consider the time-lag effects on vegetation dynamics.
Keywords	NDVI ; Climate change ; Time-lag effects ; Yamzhog Yumco Basin ; Ecology ; QH540-549.5
Subject code	550
Language	English
Publishing date	2021-05-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: The triglyceride glucose index was U-shape associated with all-cause mortality in population with cardiovascular diseases.

Li, Haiyu / Jiang, Yaohui / Su, Xin / Meng, Zhe

Diabetology & metabolic syndrome

2023 Volume 15, Issue 1, Page(s) 181

Abstract: Background: The triglyceride and glucose (TyG) index has been considered a simple surrogate marker of insulin resistance, related to a high risk of mortality. However, few studies have investigated the specific relationship between the TyG index and all- ...

Abstract	Background: The triglyceride and glucose (TyG) index has been considered a simple surrogate marker of insulin resistance, related to a high risk of mortality. However, few studies have investigated the specific relationship between the TyG index and all-cause mortality among population with cardiovascular diseases. Methods: 2,072 participants with cardiovascular diseases were enrolled from the National Health and Nutrition Examination Survey (NHANES) 1999-2014. The TyG index was calculated as log [fasting triglycerides (mg/dL) x fasting glucose (mg/dL)/2]. Outcomes were all-cause mortality and cardiovascular mortality. The baseline levels of TyG associated with the risk of mortality were evaluated on a continuous scale (restricted cubic splines) and by a priori defined quantile categories with Cox regression models. Results: After a follow-up of 16.8 years, 791 all-cause deaths and 184 cardiovascular deaths occurred. Restricted cubic splines showed that the association between levels of TyG index and the risk of all-cause mortality was non-linear (p < 0.001) and the TyG index associated with the lowest risk of all-cause mortality ranges 8.83 to 9.06 in individuals with cardiovascular diseases. Compared with the reference quartile of 8.84 ~ 9.29, the multivariate-adjusted hazards ratios and 95% confidence intervals were 1.40 (1.13-1.74; p = 0.002) in the lowest quartile and 1.08 (0.88, 1.32; p = 0.475) in the highest quartile for all-cause mortality. However, TyG was not associated with cardiovascular mortality. Conclusions: TyG index was U-shape associated with the risk of all-cause mortality in participants with cardiovascular diseases and the level associated with the lowest risk ranged 8.83 to 9.06.
Language	English
Publishing date	2023-09-07
Publishing country	England
Document type	Journal Article
ZDB-ID	2518786-7
ISSN	1758-5996
ISSN	1758-5996
DOI	10.1186/s13098-023-01153-3
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Article ; Online: 64 picosecond time resolved time-correlated single photon counting imaging.

Yang, Jia-Zhi / Zhang, An-Ning / Wu, Qing-Yuan / Li, Jian / Meng, Zhe / Zhao, Qing

The Review of scientific instruments

2024 Volume 95, Issue 2

Abstract: High-speed imaging of dynamic scenes is a challenging and important task in many applications. However, conventional imaging methods based on charge coupled devices or complementary metal oxide semiconductors have limitations in temporal resolution and ... ...

Abstract	High-speed imaging of dynamic scenes is a challenging and important task in many applications. However, conventional imaging methods based on charge coupled devices or complementary metal oxide semiconductors have limitations in temporal resolution and photon sensitivity. To address this problem, we propose a novel high-speed imaging scheme that combines single-pixel imaging with single photon detection and time-correlated single photon counting. Our scheme can achieve high-speed imaging with 64 ps resolution by repeating the motion scenes and using binary outputs from single photon detectors. We demonstrate our scheme by reconstructing the switching process of a digital micro-mirror device and a liquid crystal spatial light modulator. Our scheme can be further improved to 1 ps resolution by using a more accurate time-correlated single photon counting system. Moreover, our scheme can adapt to different speed scenes by adjusting the temporal resolution and reducing the sampling time. Our high temporal resolution imaging scheme further expands the application areas of single-pixel imaging and provides solutions for scenes requiring single photon detection and higher temporal resolution, such as reproducible chemical reaction processes imaging, cellular or sub-cellular bio imaging, single-molecule imaging of rotary motors, high-speed equipment inspection, and other periodic high-speed scenes imaging.
Language	English
Publishing date	2024-02-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	209865-9
ISSN	1089-7623 ; 0034-6748
ISSN (online)	1089-7623
ISSN	0034-6748
DOI	10.1063/5.0174067
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Article ; Online: TIRPnet: Risk prediction of traditional Chinese medicine ingredients based on a deep neural network.

Wei, Jianxiang / Dai, Jimin / Sun, Yuehong / Meng, Zhe / Ma, Hengyuan / Zhou, Yujin

Journal of ethnopharmacology

2024 Volume 325, Page(s) 117860

Abstract: Ethnopharmacological relevance: Traditional Chinese medicine (TCM) has a history of over 3000 years of medical practice. Due to the complex ingredients and unclear pharmacological mechanism of TCM, it is very difficult to predict its risks. With the ... ...

Abstract	Ethnopharmacological relevance: Traditional Chinese medicine (TCM) has a history of over 3000 years of medical practice. Due to the complex ingredients and unclear pharmacological mechanism of TCM, it is very difficult to predict its risks. With the increase in the number and severity of spontaneous reports of adverse drug reactions (ADRs) of TCM, its safety has received widespread attention. Aim of the study: In this study, we proposed a framework based on deep learning to predict the probability of adverse reactions caused by TCM ingredients and validated the model using real-world data. Materials and methods: The spontaneous reporting data from Jiangsu Province of China was selected as the research data, which included 72,561 ADR reports of TCMs. All the ingredients of these TCMs were collected from the medical website and correlated with the corresponding ADRs. Then, a risk prediction model was constructed based on a deep neural network (DNN), named TIRPnet. Based on one-hot encoded data, our model achieved the optimal performance by fine-tuning some hyperparameters. The ten most commonly used TCM ingredients and their ADRs were collected as the test set to evaluate their performance as objective criteria. Results: TIRPnet was constructed as a 7-layer DNN. The experimental results showed that TIRPnet performs excellently in all indicators, with a sensitivity of 0.950, specificity of 0.995, accuracy of 0.994, precision of 0.708, and F1 of 0.811. Conclusions: The proposed TIRPnet owns the ability to predict the ADRs of a single TCM ingredient by learning a large number of TCM-related spontaneous reports, which can help doctors design safe prescriptions and provide technical support for the pharmacovigilance of TCM.
MeSH term(s)	Humans ; Medicine, Chinese Traditional/adverse effects ; Drug-Related Side Effects and Adverse Reactions ; Neural Networks, Computer ; China ; Drugs, Chinese Herbal/adverse effects
Chemical Substances	Drugs, Chinese Herbal
Language	English
Publishing date	2024-02-03
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	134511-4
ISSN	1872-7573 ; 0378-8741
ISSN (online)	1872-7573
ISSN	0378-8741
DOI	10.1016/j.jep.2024.117860
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Article ; Online: Identification of a novel phenotype of external ear deformity related to Coffin-Siris syndrome-9 and literature review.

Wu, Ruohao / Tang, Wenting / Li, Pinggan / Meng, Zhe / Li, Xiaojuan / Liang, Liyang

American journal of medical genetics. Part A

2024 , Page(s) e63626

Abstract: De novo germline variants of the SRY-related HMG-box 11 gene (SOX11) have been reported to cause Coffin-Siris syndrome-9 (CSS-9), a rare congenital disorder associated with multiple organ malformations, including ear anomalies. Previous clinical and ... ...

Abstract	De novo germline variants of the SRY-related HMG-box 11 gene (SOX11) have been reported to cause Coffin-Siris syndrome-9 (CSS-9), a rare congenital disorder associated with multiple organ malformations, including ear anomalies. Previous clinical and animal studies have found that intragenic pathogenic variant or haploinsufficiency in the SOX11 gene could cause inner ear malformation, but no studies to date have documented the external ear malformation caused by SOX11 deficiency. Here, we reported a Chinese male with unilateral microtia and bilateral sensorineural deafness who showed CSS-like manifestations, including dysmorphic facial features, impaired neurodevelopment, and fingers/toes malformations. Using trio-based whole-exome sequencing, a de novo missense variant in SOX11 (NM_003108.4: c.347A>G, p.Y116C) was identified and classified as pathogenic variant as per American College of Medical Genetics guidelines. Moreover, a systematic search of the literature yielded 12 publications that provided data of 55 SOX11 intragenic variants affecting various protein-coding regions of SOX11 protein. By quantitatively analyzing phenotypic spectrum information related to these 56 SOX11 variants (including our case), we found variants affecting different regions of SOX11 protein (high-mobility group [HMG] domain and non-HMG regions) appear to influence the phenotypic spectrum of organ malformations in CSS-9; variants altering the HMG domain were more likely to cause the widest range of organ anomalies. In summary, this is the first report of CSS with external ear malformation caused by pathogenic variant in SOX11, indicating that the SOX11 gene may be not only essential for the development of the inner ear but also critical for the morphogenesis of the external ear. In addition, thorough clinical examination is recommended for patients who carry pathogenic SOX11 variants that affect the HMG domain, as these variants may cause the widest range of organ anomalies underlying this condition.
Language	English
Publishing date	2024-04-09
Publishing country	United States
Document type	Case Reports
ZDB-ID	2108614-X
ISSN	1552-4833 ; 0148-7299 ; 1552-4825
ISSN (online)	1552-4833
ISSN	0148-7299 ; 1552-4825
DOI	10.1002/ajmg.a.63626
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Article ; Online: Association between ankle-brachial blood pressure index with all-cause and cardiovascular mortality in adults without arterial stiffness.

Meng, Zhe / Jiang, Yaohui / Xu, Chang / Zheng, Huifen / Li, Haiyu

BMC geriatrics

2023 Volume 23, Issue 1, Page(s) 635

Abstract: Purpose: To explore the relationship between ankle-brachial blood pressure index (ABPI) and all-cause or cardiovascular mortality in adults without arterial stiffness.: Methods: A total of 6784 participants without arterial stiffness were enrolled ... ...

Abstract	Purpose: To explore the relationship between ankle-brachial blood pressure index (ABPI) and all-cause or cardiovascular mortality in adults without arterial stiffness. Methods: A total of 6784 participants without arterial stiffness were enrolled from National Health and Nutrition Examination Survey 1999-2004. The hazard ratio (HR) and 95% confidence interval (CI) of ABPI associating with the risk of all-cause and cardiovascular mortality was calculated by Cox proportional regression models adjusted for demographic and traditional risk factors. Dose-response relationship was explored with restricted cubic spines. Results: After an average follow-up of 12.1 years, 1844 all-cause deaths and 299 cardiovascular deaths occurred. Compared with the lowest ABPI quartile, the second quartile was associated with the lowest risk of all-cause mortality (HR 0.89, 95%CI 0.79-0.98; p = 0.036) and cardiovascular mortality (HR 0.75, 95%CI 0.56-0.98; p = 0.048). Besides, dose-response analysis revealed that ABPI was nonlinearly correlated to all-cause mortality (p for nonlinearity < 0.001) and linearly correlated to cardiovascular mortality (p for nonlinearity = 0.459). Conclusions: The relationship between ABPI and all-cause and cardiovascular mortality followed a L-shape curve. A lower ABPI was independently associated with an increased risk of all-cause and cardiovascular mortality in adults without arterial stiffness.
MeSH term(s)	Humans ; Blood Pressure ; Cardiovascular Diseases ; Vascular Stiffness ; Ankle/blood supply ; Nutrition Surveys ; Ankle Brachial Index/adverse effects ; Risk Factors
Language	English
Publishing date	2023-10-09
Publishing country	England
Document type	Journal Article
ZDB-ID	2059865-8
ISSN	1471-2318 ; 1471-2318
ISSN (online)	1471-2318
ISSN	1471-2318
DOI	10.1186/s12877-023-04332-z
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Article: Construction of pyrroles, furans and thiophenes

Meng, Zhe / Yan, Jun / Ning, Chao / Shi, Min / Wei, Yin

Chemical science

2023 Volume 14, Issue 28, Page(s) 7648–7655

Abstract: Pyrroles, furans, and thiophenes are important structural motifs in biologically active substances, pharmaceuticals and functional materials. In this paper, we disclose an efficient synthetic strategy for the rapid construction of multisubstituted ... ...

Abstract	Pyrroles, furans, and thiophenes are important structural motifs in biologically active substances, pharmaceuticals and functional materials. In this paper, we disclose an efficient synthetic strategy for the rapid construction of multisubstituted pyrroles, furans, and thiophenes
Language	English
Publishing date	2023-06-13
Publishing country	England
Document type	Journal Article
ZDB-ID	2559110-1
ISSN	2041-6539 ; 2041-6520
ISSN (online)	2041-6539
ISSN	2041-6520
DOI	10.1039/d3sc01542d
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