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Article ; Online: Experimental study on the thermal performance of ultra-thin flat heat pipes with novel multiscale striped composite wick structures

Menghao Wang / Yinchuang Yang / Yiwei Sun / Jian Li / Menglong Hao

Heliyon, Vol 9, Iss 10, Pp e20840- (2023)

2023

Abstract: The rapid development of power-intensive and flexible electronic devices requires thinner heat-dissipation devices with better thermal performance. Ultra-thin flat heat pipe (UTFHP) with striped wick structure is a promising candidate for this ... ...

Abstract	The rapid development of power-intensive and flexible electronic devices requires thinner heat-dissipation devices with better thermal performance. Ultra-thin flat heat pipe (UTFHP) with striped wick structure is a promising candidate for this application, but its wick structure and thermal performance have not yet been thoroughly studied and optimized for the small concentrated heat source, which is commonly encountered in electronics. In this study, several concentrated striped composite wick (CSCW) structures for 0.6 mm thick UTFHPs are proposed and experimentally investigated. The CSCW consists of copper foam with striped passages converging in the heating zone and double layers of copper screen mesh. The thermal performance of UTFHPs with various composite wick structures is experimentally evaluated. UTFHPs with the proposed structures are also compared with a UTFHP with a more conventional parallel passage composite wick structure. Experimental results show that the CSCW with the hollow structure at the evaporation section is preferred, due to the directed liquid working medium reflux and a large vapor-liquid evaporation interface. Besides, the passage width of the copper foam significantly affects the thermal performance. With the best-performing wick structure, the UTFHP gives the lowest thermal resistance of 0.79 °C/W at a heat load of 23.34 W. Its effective thermal conductivity is approximately 7 times that of copper. The proposed striped wick structure for UTFHPs provides an alternative to handle the hot-spot challenge of electronic devices.
Keywords	Ultra-thin flat heat pipe ; Striped composite wick ; Multiscale ; Thermal resistance ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
Subject code	621
Language	English
Publishing date	2023-10-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Identification of potential key genes associated with termination phase of rat liver regeneration through microarray analysis

Haitham Salameen / Menghao Wang / Jianping Gong

Journal of Men's Health, Vol 18, Iss 1, p

2021 Volume 002

Abstract: Background and objective: Liver regeneration (LR) is a complex process influenced by various genes and pathways, the majority of the of research on LR focus on the initiation and proliferation phase while studies on termination phase is lacking. We aimed ...

Abstract	Background and objective: Liver regeneration (LR) is a complex process influenced by various genes and pathways, the majority of the of research on LR focus on the initiation and proliferation phase while studies on termination phase is lacking. We aimed to identify potential genes and reveal the underlying the molecular mechanisms involved in the precise regulation of liver size during the termination phase of LR. Materials and methods: We obtained the rat liver tissue gene datasets (GSE63742) collected following partial hepatectomy (PH) from the Gene Expression Omnibus (GEO) of the National Center for Biotechnology Information (NCBI), from which, this study screened the late stage LR samples (7 days post-PH) using the R/Bioconductor packages for the identification of differentially expressed genes (DEGs). Afterwards, we performed enrichment analysis using the database for annotation visualization and integrated discovery (DAVID) online tool. Moreover, the Search Tool for the Retrieval of Interacting proteins (STRING) database was employed to construct protein-protein interaction (PPI) networks based on those identified DEGs; the PPI network was then used by Cytoscape software to predict hub genes and nodes. Animal experimentation (Rat PH model) was performed to acquire liver tissues which were then used for western blot analysis to verify our results. Results: The present study identified together 74 significant DEGs, among which, 51 showed up-regulation while 23 presented as down-regulated. As revealed by KEGG pathway enrichment analysis, DEGs were mostly related to pathways such as retinol metabolism, steroid hormone synthesis, transforming growth factor-β (TGF-β) and mitogen-activated protein kinase (MAPK) signaling. In addition, as suggested by GO enrichment analysis, DEGs were mostly related to the cyclooxygenase P450 pathway, negative regulation of Notch signaling pathway, aromatase activity, steroid hydroxylase activity, exosomes, and extracellular domain. Analyses based on STRING database and Cytoscape ...
Keywords	liver regeneration ; differentially expressed genes ; enrichment analysis ; protein-protein interaction networks ; Medicine (General) ; R5-920
Subject code	570
Language	English
Publishing date	2021-06-01T00:00:00Z
Publisher	MRE Press
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A new non-stationary standardised streamflow index using the climate indices and the optimal anthropogenic indices as covariates in the Wei River Basin, China

Mingming Ren / Shanhu Jiang / Liliang Ren / Baisha Weng / Menghao Wang / Hao Cui / Chong-Yu Xu

Journal of Hydrology: Regional Studies, Vol 51, Iss , Pp 101649- (2024)

2024

Abstract: Study region: Catchment area above the Huaxian station along the Wei River Basin, China. Study focus: This study attempts to construct a new Non-stationary Standardized Streamflow Index (NSSI) applicable to the variable streamflow sequence of the Wei ... ...

Abstract	Study region: Catchment area above the Huaxian station along the Wei River Basin, China. Study focus: This study attempts to construct a new Non-stationary Standardized Streamflow Index (NSSI) applicable to the variable streamflow sequence of the Wei River Basin based on the climate index and the optimal anthropogenic index, and analyse the drought characteristics of the basin. The climate index is used to quantify climate change factors and three anthropogenic indices are used to quantify the factor of human activities, including the reservoir index, the human-induced index calculated based on the Variable Infiltration Capacity (VIC) hydrological model and the Long Short-Term Memory (LSTM) model machine learning approach, respectively. New hydrological insights for the region: The human-induced index based on the LSTM model is more suitable for quantifying anthropogenic factors in the Wei River Basin. The NSSI performs better than the SSI in drought identification. The NSSI based on the LSTM model can capture more frequent severe drought and extreme drought events. The frequency of severe drought and extreme drought is higher in summer and autumn than in the others. The NSSI can better characterize the hydrological drought processes under a non-stationary condition, thus it can provide a more effective reference for regional drought assessment and related policy-making from the perspective of a changing environment.
Keywords	Non-stationary standardized streamflow index ; Hydrological drought ; Climate index ; Anthropogenic index ; Physical geography ; GB3-5030 ; Geology ; QE1-996.5
Subject code	550
Language	English
Publishing date	2024-02-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Exploration on the Improvement of Cognitive Function and Inflammatory Response in Perimenopausal Patients with Mild Cognitive Impairment by Self-Prepared Ningshen Prescription

Wei Yang / Yumei Ye / Yan Cai / Guiyan Wang / Menghao Wang / Xiaodan Zhang

Evidence-Based Complementary and Alternative Medicine, Vol

2022 Volume 2022

Abstract: Objective. To investigate the improvement of cognitive function and inflammatory response in perimenopausal patients with MCI by kidney-tonifying, blood-activating, and mind-nourishing. Methods. 80 perimenopausal patients with MCI who met the diagnostic ... ...

Abstract	Objective. To investigate the improvement of cognitive function and inflammatory response in perimenopausal patients with MCI by kidney-tonifying, blood-activating, and mind-nourishing. Methods. 80 perimenopausal patients with MCI who met the diagnostic criteria were divided into a therapy group (n = 40) and a control group (n = 40) according to the treatment method. The control group was given nimodipine (Bayer Pharmaceuticals) 30 mg, 3 times/day orally, while the therapy group was given a decoction of self-prepared Ningshen prescription on the top of the control group (glossy privet fruit, mulberry, aizoon stonecrop, dan-shen root, tuber fleeceflower stem, cyperus rotundus, citron). Patients in the 2 groups were assessed on the MocA scale, ADL scale, and TCM symptom score before and after 2 months of treatment, respectively, to observe whether there was any change in the scale scores and in the levels of inflammatory factors (hs-CRP, Hcy, and IL-1β) Pre- and posttherapy in the 2 groups. Observe the improvement of clinical symptoms and their safety in both groups (liver and kidney function indicators such as ALT, AST and Cr, dizziness, headache, decrease in blood pressure, flushing, and gastrointestinal reactions). Results. The efficacy of the therapy group was better than that of the control group; the MocA scale and ADL scale scores improved and the TCM symptom score decreased in both groups posttherapy, with the MocA scale and ADL scale scores improving more and the TCM symptom score decreasing more in the therapy group compared with the control group during the same period (p<0.05). The serum levels of hs-CRP, Hcy, and IL-1β decreased in both groups posttherapy, with the serum levels of hs-CRP, Hcy, and IL-1β decreasing more in the therapy group compared to the control group during the same period (p<0.05). The difference in adverse events between the two groups was not statistically significant when compared by a chi-square test (p>0.05). The differences in ALT, AST, and Cr levels between the ...
Keywords	Other systems of medicine ; RZ201-999
Subject code	616
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Dynamics and potential synchronization of regional precipitation concentration and drought-flood abrupt alternation under the influence of reservoir climate

Hao Cui / Shanhu Jiang / Liliang Ren / Weihua Xiao / Fei Yuan / Menghao Wang / Linyong Wei

Journal of Hydrology: Regional Studies, Vol 42, Iss , Pp 101147- (2022)

2022

Abstract: Study region: Three Gorges Reservoir area, the largest reservoir area in China Study focus: The frequency and intensity of extreme weather events increase with climate warming, and the local climate effects in the large reservoir area may also change the ...

Abstract	Study region: Three Gorges Reservoir area, the largest reservoir area in China Study focus: The frequency and intensity of extreme weather events increase with climate warming, and the local climate effects in the large reservoir area may also change the local precipitation structure. Therefore, based on the precipitation sequence data in the Three Gorges Reservoir (TGR) area from 1959 to 2019, the proposed multi-time-scale mutual information entropy (MTSMIE) method was used to reveal the cyclic synchronous changes of drought-flood abrupt alternation and precipitation concentration. New hydrological insights: The results demonstrate that (1) the spatial distribution of the precipitation concentration index in the TGR area has obvious regional variability. On the temporal scale, the precipitation concentration increased by 5.5% and decreased by 8.2% after impoundment at the head and tail of the TGR, respectively. (2) The frequency of drought-to-flood (DTF) events from the head of the reservoir area to the tail of the reservoir area presents a ''more-less'' feature. The frequency of DTF events after impoundment was less than that before the impoundment of the reservoir. However, the flood-to-drought (FTD) events are the opposite. (3) The period of reliable research and monitoring of DFAA and precipitation concentration in the Three Gorges region is about 15–17 years through the MTSMIE method.
Keywords	Precipitation concentration ; Spatiotemporal distribution ; Drought-flood abrupt alternation ; MTSMIE ; Three Gorges Reservoir ; Physical geography ; GB3-5030 ; Geology ; QE1-996.5
Subject code	910 ; 550
Language	English
Publishing date	2022-08-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Quantifying the impact of climate change and human activities on the eco-hydrological regimes of the Weihe River Basin, Northwest China

Shanhu Jiang / Yating Liu / Menghao Wang / Yongwei Zhu / Hao Cui / Shuping Du / Chong-Yu Xu

Hydrology Research, Vol 54, Iss 1, Pp 49-

2023 Volume 64

Abstract: Climate change and anthropogenic interventions have obviously altered the eco-hydrological regimes. A quantitative evaluation and attribution of the eco-hydrological alterations are urgently required. In this study, we evaluated the various attributions ... ...

Abstract	Climate change and anthropogenic interventions have obviously altered the eco-hydrological regimes. A quantitative evaluation and attribution of the eco-hydrological alterations are urgently required. In this study, we evaluated the various attributions of eco-hydrological regimes in the Weihe River Basin (WRB). Firstly, the trends and change-point analysis of hydrological elements were examined, and the natural streamflow was reproduced based on the variable infiltration capacity model. Then, the most ecologically relevant hydrological indicators (ERHIs) were selected and combined with the eco-deficit and eco-surplus indicators to assess the degree of eco-hydrological regime alterations. Finally, the relative contributions to eco-hydrological alterations were quantified using the ‘simulated–observed comparison’ method. The results showed that (1) the streamflow of the WRB exhibited significant decreasing trends (p < 0.01), and a significant change point (p < 0.01) of the streamflow series was identified in 1990. (2) Seven representative indicators of hydrological alteration were selected as ERHIs. (3) During the human-induced period (1991–2017), human activities were the dominant factors in the eco-hydrological alterations as well as the variations of the ERHI indexes and the eco-deficit and eco-surplus metrics. Overall, the proposed framework may improve the understanding of the driving forces of eco-hydrological regime alterations under a changing environment. HIGHLIGHTS The principal component analysis was used to remove redundancy and correlation among the indicators of hydrological alterations and determine the ecologically relevant hydrological indicators.; A combination of ERHIs and eco-metrics to assess the eco-hydrological regime alterations at different time scales is used.; The effects of climate change and anthropogenic activities on the eco-hydrological regime alterations were quantitatively distinguished.;
Keywords	changing environment ; eco-deficit ; eco-hydrological regime ; eco-surplus ; weihe river basin ; River ; lake ; and water-supply engineering (General) ; TC401-506 ; Physical geography ; GB3-5030
Subject code	550
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	IWA Publishing
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: An integrated approach for identification and quantification of ecological drought in rivers from an ecological streamflow perspective

Shanhu Jiang / Menghao Wang / Liliang Ren / Yating Liu / Le Zhou / Hao Cui / Chong-Yu Xu

Ecological Indicators, Vol 143, Iss , Pp 109410- (2022)

2022

Abstract: Although various studies have investigated the impacts of climate variability and human activities on drought, researches specifically analysing the impact on ecological drought are still limited. A deep understanding of the climatic and anthropogenic ... ...

Abstract	Although various studies have investigated the impacts of climate variability and human activities on drought, researches specifically analysing the impact on ecological drought are still limited. A deep understanding of the climatic and anthropogenic effects on ecological drought processes is crucial for ecological regulation and management in the changing environments. In the present study, an integrated approach for comprehensive understanding and quantification of ecological drought in rivers was proposed which first applied the nonparametric kernel density estimation (KDE) method to calculate the most suitable ecological streamflow (MSES) for a river ecosystem. Then, the variable threshold level method based on the MSES for each month and the run theory method were applied to identify the ecological drought duration and deficit volumes. Finally, a quantification approach based on hydrological model simulation was proposed to attribute the impacts of climate variability and human activities on ecological drought. The proposed approach was applied on two catchments, Xianyang (XY) and Huaxian (HX) within the Weihe River Basin (WRB) in northern China. Comparison results obtained using the two empirical methods revealed that the MSES calculated using the KDE method was reasonable and can be used for ecological drought identification. The identification results showed that both the median and upper quartile values of the drought duration and deficit volumes during the disturbed period (1991–2017) were greater than those during the undisturbed period (1961–1990). Quantification results showed that human activities were the dominant factor aggravating ecological drought in the WRB after 1990. The contribution rates of climate variability and human activities toward ecological drought variations were 25.6% and 74.4%, respectively, for the XY station and 42.7% and 57.3%, respectively, for the HX station. Although the WRB was selected as a case study, the proposed approach can also be applied to other regions to ...
Keywords	Ecological streamflow ; Variable threshold method ; Ecological drought ; Climate change ; Human activities ; Ecology ; QH540-549.5
Subject code	910
Language	English
Publishing date	2022-10-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Preliminary Utility of the Retrospective IMERG Precipitation Product for Large-Scale Drought Monitoring over Mainland China

Linyong Wei / Shanhu Jiang / Liliang Ren / Linqi Zhang / Menghao Wang / Zheng Duan

Remote Sensing, Vol 12, Iss 2993, p

2020 Volume 2993

Abstract: This study evaluated the suitability of the latest retrospective Integrated Multi-satellitE Retrievals for Global Precipitation Measurement V06 (IMERG) Final Run product with a relatively long period (beginning from June 2000) for drought monitoring over ...

Abstract	This study evaluated the suitability of the latest retrospective Integrated Multi-satellitE Retrievals for Global Precipitation Measurement V06 (IMERG) Final Run product with a relatively long period (beginning from June 2000) for drought monitoring over mainland China. First, the accuracy of IMERG was evaluated by using observed precipitation data from 807 meteorological stations at multiple temporal (daily, monthly, and yearly) and spatial (pointed and regional) scales. Second, the IMERG-based standardized precipitation index (SPI) was validated and analyzed through statistical indicators. Third, a light–extreme–light drought-event process was adopted as the case study to dissect the latent performance of IMERG-based SPI in capturing the spatiotemporal variation of drought events. Our results demonstrated a sufficient consistency and small error of the IMERG precipitation data against the gauge observations with the regional mean correlation coefficient (CC) at the daily (0.7), monthly (0.93), and annual (0.86) scales for mainland China. The IMERG possessed a strong capacity for estimating intra-annual precipitation changes; especially, it performed well at the monthly scale. There was a strong agreement between the IMERG-based SPI values and gauge-based SPI values for drought monitoring in most regions in China (with CCs above 0.8). In contrast, there was a comparatively poorer capability and notably higher heterogeneity in the Xinjiang and Qinghai-Tibet Plateau regions with more widely varying statistical metrics. The IMERG featured the advantage of satisfactory spatiotemporal accuracy in terms of depicting the onset and extinction of representative drought disasters for specific consecutive months. Furthermore, the IMERG has obvious drought monitoring abilities, which was also complemented when compared with the Remotely Sensed Information using Artificial Neural Networks Climate Data Record (PERSIANN-CDR), Climate Hazards Group Infrared Precipitation with Stations (CHIRPS), and Tropical Rainfall Measuring ...
Keywords	retrospective IMERG ; standardized precipitation index ; drought monitoring ; mainland China ; Science ; Q
Subject code	910
Language	English
Publishing date	2020-09-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: IL-4 Alleviates Ischaemia-Reperfusion Injury by Inducing Kupffer Cells M2 Polarization via STAT6-JMJD3 Pathway after Rat Liver Transplantation

Minghua Deng / Jingyuan Wang / Hao Wu / Menghao Wang / Ding Cao / Jinzheng Li / Yakun Wu / Jianping Gong

BioMed Research International, Vol

2020 Volume 2020

Abstract: Background. Liver ischaemia-reperfusion injury (IRI) remains a problem in liver transplantation. Interleukin-4 (IL-4) has been found to reduce liver IRI, but the exact mechanism remains unclear. Methods. Donor livers were infused with recombinant IL-4 or ...

Abstract	Background. Liver ischaemia-reperfusion injury (IRI) remains a problem in liver transplantation. Interleukin-4 (IL-4) has been found to reduce liver IRI, but the exact mechanism remains unclear. Methods. Donor livers were infused with recombinant IL-4 or normal saline during cold storage, and the hepatocellular apoptosis and the inflammatory response were detected. The effect of IL-4 treatment on Kupffer cells (KCs) polarization and expression of the STAT6-JMJD3 pathway was evaluated in vivo and in vitro. KCs in donor livers were depleted by clodronate liposome treatment or JMJD3 was inhibited by GSK-J4 before liver transplantation to determine whether the protective effect of IL-4 treatment was dependent on KCs. Results. IL-4 treatment decreased sALT and sAST levels and alleviated hepatocellular apoptosis and inflammation at 6 h after liver transplantation. IL-4 treatment induced KCs alternatively activated (M2) polarization in vitro and in vivo, and the expression of STAT6 and JMJD3 was increased. JMJD3 knockdown abolished KCs M2 polarization and reduced the antiapoptotic and anti-inflammatory effects induced by IL-4 treatment in vitro. In addition, the protection of IL-4 treatment against IRI induced by liver transplantation was significantly reduced after the depletion of KCs or the inhibition of JMJD3 in donor livers. Conclusions. IL-4 treatment-induced KCs M2 polarization was dependent on the STAT6-JMJD3 pathway and protected liver grafts from IRI after liver transplantation.
Keywords	Medicine ; R
Subject code	610
Language	English
Publishing date	2020-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Wellbore temperature distribution during circulation stage when well-kick occurs in a continuous formation from the bottom-hole

Zhang, Zheng / Youming Xiong / Yun Gao / Liming Liu / Menghao Wang / Geng Peng

Energy. 2018 Dec. 01, v. 164

2018

Abstract: In the exploration and development of deep reservoir resources, the occurrence of well kick will have a very important impact on wellbore temperature distribution during circulation. This study aims to investigate the wellbore temperature distribution ... ...

Abstract	In the exploration and development of deep reservoir resources, the occurrence of well kick will have a very important impact on wellbore temperature distribution during circulation. This study aims to investigate the wellbore temperature distribution during circulation when well kick occurs in a continuous formation from the bottom-hole. A transient temperature model was established by the first law of thermodynamics. The finite volume method was used to discretize the model and the under-relaxation iterative method was used for numerical calculation. The validity of the model has been verified by the previous typical models and actual measured temperatures. The calculation results showed that the highest temperature of annulus fluid was at the bottom-hole and annulus fluid temperature increased as the formation high-temperature fluid continuously enters the annulus when well kick occurred. The occurrence of well kick led to a significant increase in outlet fluid temperature and bottom-hole fluid temperature. The occurrence of well kick changed the formation radial temperature distribution and the temperature difference distribution between the annulus fluid and the drilling fluid inside the drill string. The flow rate of the well kick and the location of the well kick occurred also had an important impact on wellbore temperature distribution.
Keywords	models ; temperature ; thermodynamics
Language	English
Dates of publication	2018-1201
Size	p. 964-977.
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	2019804-8
ISSN	0360-5442 ; 0360-5442
ISSN (online)	0360-5442
ISSN	0360-5442
DOI	10.1016/j.energy.2018.09.048
Database	NAL-Catalogue (AGRICOLA)

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