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  1. AU="Mengliang Ye"
  2. AU=Tosi Gian Marco
  3. AU=Zaffran Stephane
  4. AU=Major E O
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  6. AU="Karlsen, Allan E"
  7. AU="Andrea Russo"
  8. AU="Yang, Liuliu"
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  10. AU="Montani, Rosana S"
  11. AU=Zhou Peiyuan AU=Zhou Peiyuan
  12. AU="Rachel Rossiter"
  13. AU="Hiovain-Asikainen, Katri"
  14. AU="Zehl, Martin"
  15. AU="Schmidt, Joel T"
  16. AU="Nguyen Quoc Hung"
  17. AU="Lucia Landoni"
  18. AU="Singh, Pawan"
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  26. AU="Lauren A Holt"
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  28. AU="Santos, Bryan" AU="Santos, Bryan"
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  30. AU="Havva Keskin"
  31. AU="Gomis, Susantha"
  32. AU="Castro, Vanda"
  33. AU="Josiah, S M"
  34. AU="Yanjun Guo"
  35. AU="Klapp, Sabine H L"
  36. AU="Cipolat, Lauriane"
  37. AU="Rhee, Hwanseok"
  38. AU="El-Khatabi, K"
  39. AU="Lee, Seung Hee"
  40. AU=Torres Antoni
  41. AU="Baldacini, Mathieu"
  42. AU="Stahl, Alexander"
  43. AU="Karimbumkara, Seena Narayanan"
  44. AU="Welz Mirosław"
  45. AU="Jintao Ding"
  46. AU="Mei-Fang Chen"

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  1. Artikel ; Online: Epidemiological and Clinical Characteristics of Influenza Outbreaks Among Children in Chongqing, China

    Xuchen Meng / Han Zhao / Rong Ou / Qing Zeng / Huiqun Lv / Hua Zhu / Mengliang Ye

    Frontiers in Public Health, Vol

    2022  Band 10

    Abstract: Influenza is a global serious public health threat. Seasonal influenza among children in Chongqing has been a heavy health burden. To date, few studies have examined the spatial and temporal characteristics of influenza. This research sheds new light on ... ...

    Abstract Influenza is a global serious public health threat. Seasonal influenza among children in Chongqing has been a heavy health burden. To date, few studies have examined the spatial and temporal characteristics of influenza. This research sheds new light on correlating them with influenza outbreaks with data of over 5 years (2014–2018). All cluster outbreaks among preschool and school-age children reported in Chongqing were collected through the Public Health Emergency Management Information System. The demographical, epidemiological, and clinical data of the cases were analyzed. From 2014 to 2018, a total of 111 preschool- and school-based influenza-like illness outbreaks involving 3,549 cases were identified. Several clinical symptoms that were analyzed in this study showed significant contrast between influenza A and B. Spatial autocorrelation analysis over the 5-year data detected Xiushan district being the most likely cluster. The exploration of the spatial distribution and clinical characteristics of influenza cluster of children in Chongqing could help the effective implementation of health policies. Future studies should be conducted to monitor the outbreaks of influenza among children.
    Schlagwörter influenza ; epidemiological characteristics ; preschool and school-age children ; influenza outbreak ; spatial autocorrelation analysis (SAA) ; Public aspects of medicine ; RA1-1270
    Sprache Englisch
    Erscheinungsdatum 2022-04-01T00:00:00Z
    Verlag Frontiers Media S.A.
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  2. Artikel ; Online: Condom Use and Related Factors among Rural and Urban Men Who Have Sex With Men in Western China

    Ling Hu / Yetao Luo / Xiaoni Zhong / Rongrong Lu / Yang Wang / Manoj Sharma / Mengliang Ye

    American Journal of Men's Health, Vol

    Based on Information-Motivation-Behavioral Skills Model

    2020  Band 14

    Abstract: This study aimed to determine the differences in condom use and related factors among rural–urban men who have sex with men (MSM) in Western China. A cross-sectional survey was conducted in Chongqing, Sichuan, and Guangxi, which recruited MSM by non- ... ...

    Abstract This study aimed to determine the differences in condom use and related factors among rural–urban men who have sex with men (MSM) in Western China. A cross-sectional survey was conducted in Chongqing, Sichuan, and Guangxi, which recruited MSM by non-probability sampling. Data were collected through an anonymous, standardized, and self-reported questionnaire guided by an information–motivation–behavioral skills model. Structural equation model was applied to analyze the related factors. Out of the 1141 MSM included in this analysis, 856 (75%) and 285 (25%) were from urban and rural areas, respectively. The median age was 27 years for both groups. Self-reported consistent condom use for anal sex in the past 6 months was 57.58%. The rate of consistent condom use was lower in rural MSM than in urban MSM (50.88% vs. 59.81%, p = .008). Behavioral skills, HIV/AIDS intervention services, and response costs had direct positive and negative influences on condom use, respectively. By contrast, motivation and information exhibited indirect influence. All the factors were mediated by behavioral skills in rural and urban MSM, except for the information that had no effect among urban MSM but had an indirect effect among rural MSM. These findings suggest that service providers should pay attention to substantial rural–urban differences and design different AIDS prevention and intervention strategies targeting rural and urban MSM.
    Schlagwörter Medicine ; R
    Thema/Rubrik (Code) 150
    Sprache Englisch
    Erscheinungsdatum 2020-02-01T00:00:00Z
    Verlag SAGE Publishing
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  3. Artikel ; Online: Epidemiological Characteristics and Spatiotemporal Analysis of Acute Hemorrhagic Conjunctivitis from 2004 to 2018 in Chongqing, China

    Dan Jing / Han Zhao / Rong Ou / Hua Zhu / Ling Hu / Mohan Giri / Mengliang Ye

    Scientific Reports, Vol 10, Iss 1, Pp 1-

    2020  Band 8

    Abstract: Abstract Chongqing is one of the five provinces in China that has the highest incidence of acute hemorrhagic conjunctivitis (AHC). Data of AHC cases from 2004 to 2018 were obtained from National Notifiable Diseases Reporting Information System (NNDRIS). ... ...

    Abstract Abstract Chongqing is one of the five provinces in China that has the highest incidence of acute hemorrhagic conjunctivitis (AHC). Data of AHC cases from 2004 to 2018 were obtained from National Notifiable Diseases Reporting Information System (NNDRIS). Descriptive statistical methods were used to analyze the epidemiological characteristics; incidence maps were used to reflect incidence trends in each district; spatial autocorrelation was used to identify hotspot regions and spatiotemporal patterns of AHC outbreaks; spatiotemporal scan were conducted to identify AHC clusters. A total of 30,686 cases were reported with an annual incidence of 7.04 per 100,000. The incidence rates were high in 2007 and 2014, and large epidemics were observed in 2010 with the seasonal peak in September. Individuals aged 10–19 years, males, students and farmers were the prime high-risk groups. Except for 2012 and 2013, the spatial distribution of AHC did not exhibit significant global spatial autocorrelation. Local indicators of spatial association showed that the high-risk regions are Chengkou and Wuxi. The spatiotemporal scan indicated that all clusters occurred in September 2010, and the high-incidence clusters were mainly distributed in the northeast of Chongqing. The results could assist public health agencies to consider effective preventive measures based on epidemiological factors and spatiotemporal clusters in different regions.
    Schlagwörter Medicine ; R ; Science ; Q
    Sprache Englisch
    Erscheinungsdatum 2020-06-01T00:00:00Z
    Verlag Nature Publishing Group
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  4. Artikel ; Online: Changing trends of HIV, syphilis, HCV infections and behavioural factors among female sex workers in Chongqing, China

    Hua Zhu / Guohui Wu / Rongrong Lu / Hongfang Qiu / Dan Jing / Mengliang Ye

    BMJ Open, Vol 10, Iss

    findings from six serial surveillance surveys

    2020  Band 10

    Abstract: Objectives To explore the prevalence and changing trends of HIV, syphilis, hepatitis C virus (HCV) infections and risk behaviours among female sex workers (FSWs) and to provide reference and theoretical basis for formulating targeted interventions.Design ...

    Abstract Objectives To explore the prevalence and changing trends of HIV, syphilis, hepatitis C virus (HCV) infections and risk behaviours among female sex workers (FSWs) and to provide reference and theoretical basis for formulating targeted interventions.Design Six consecutive cross-sectional surveys.Setting Chongqing, China.Participants FSWs were included if they (1) were aged ≥16 years, (2) provided commercial sex for money or goods during the previous month and (3) were willing to participate in the survey and could provide verbal informed consent. This study included 16 791 of 16 810 participants recruited between 2013 and 2018.Primary and secondary outcome measures The prevalence of HIV/syphilis/HCV infection.Results The HIV and HCV prevalence among FSWs in Chongqing was stable during the study period, but the prevalence of syphilis had an increasing trend, particularly among low-tier and middle-tier FSWs. Improvements in HIV-related knowledge, condom use, injecting drug use and participation in HIV-related services were observed. However, no change was found in the prevalence of drug use. HIV infection was correlated with no condom use in the last commercial sex (adjusted OR (aOR) 3.48, 95% CI 1.90 to 6.37) and syphilis infection (aOR 4.88, 95% CI 1.95 to 12.18). Syphilis infection was correlated with inconsistent condom use (aOR 1.30, 95% CI 1.02 to 1.65), HIV infection (aOR 5.88, 95% CI 2.40 to 14.41), HCV infection (aOR 7.68, 95% CI 4.37 to 13.49) and sexually transmitted infection (STI) diagnosis in the past year (aOR 3.81, 95% CI 2.40 to 6.03). HCV infection was associated with injecting drug use (aOR 8.91, 95% CI 4.45 to 17.86) and syphilis infection (aOR 7.88, 95% CI 4.49 to 13.83).Conclusions Comprehensive interventions targeting FSWs, particularly low-tier and middle-tier FSWs, should be increasingly implemented to prevent and control HIV, syphilis and other STIs.
    Schlagwörter Medicine ; R
    Thema/Rubrik (Code) 360
    Sprache Englisch
    Erscheinungsdatum 2020-10-01T00:00:00Z
    Verlag BMJ Publishing Group
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  5. Artikel ; Online: Changing Trends of HIV, Syphilis, and Hepatitis C among Male Migrant Workers in Chongqing, China

    Yujun Wang / Rongrong Lu / Guohui Wu / Rong Lan / Rong Ou / Yangchang Zhang / Mengliang Ye

    International Journal of Environmental Research and Public Health, Vol 17, Iss 3, p

    Nine Consecutive Cross-Sectional Surveys, 2010–2018

    2020  Band 875

    Abstract: Background: Male migrant workers (MMWs) have been reported to be vulnerable to human immunodeficiency virus (HIV) and other sexually transmitted infections (STIs). Chongqing, China is one of the major migration destinations and hotspots of HIV. This ... ...

    Abstract Background: Male migrant workers (MMWs) have been reported to be vulnerable to human immunodeficiency virus (HIV) and other sexually transmitted infections (STIs). Chongqing, China is one of the major migration destinations and hotspots of HIV. This study aims to explore the prevalence of HIV, syphilis, and hepatitis C virus (HCV), as well as HIV-related knowledge and behaviors, among MMWs in Chongqing. Methods: Questionnaire surveys were conducted, and blood samples were collected and examined among MMWs selected by two-stage stratified sampling in Chongqing from 2010 to 2018. The Cochran−Armitage trend test was conducted to observe the trends in the prevalence of HIV, syphilis, and HCV, as well as HIV-related knowledge and behaviors. The Chi-square test and Binary Logistic Regression were conducted to observe the distinctions between different groups. Results: The overall HIV prevalence was 0.6% with an increasing trend (0.2% to 0.9%, p < 0.001), whereas the overall HCV prevalence was 0.5% with a decreasing trend (0.5% to 0.4%, p < 0.001). The overall syphilis prevalence was 1.3% in the ≥50 age group, 1.0% in the 30−49 age group, and higher than 0.3% in the 16−29 group ( X 2 = 19.527, p < 0.001). An uptrend (80.2%−80.6%, p < 0.001) was observed in correct HIV-related knowledge. The 16−29 ((Odds Ratio) OR: 1.575; 95%CI (Confidence Interval): 1.380−1.798; p < 0.001) and 30−49 (OR: 1.697; 95%CI: 1.495−1.926; p < 0.001) age groups had 1.575 and 1.697 times correct HIV-related knowledge more than the ≥50 age group. The proportion of subjects engaged in commercial sex in the past year (7.7%−13.3%, p < 0.001), consistent condom use during this activity (20.5%−54.0%, p < 0.001), and condom use in the last commercial sex (48.6%−72.1%, p = 0.020) were increasing. The risk of engaging in commercial sex in the past year in the 16−29 age group was 0.768 times (OR: 0.768; 95%CI: 0.643−0.917; p = 0.003) less than that in the ≥50 age group. The risk of engaging in non-regular sex in the past year in ...
    Schlagwörter male migrant workers ; hiv ; syphilis ; hcv ; stis ; chongqing ; cross-sectional survey ; Medicine ; R
    Thema/Rubrik (Code) 590
    Sprache Englisch
    Erscheinungsdatum 2020-01-01T00:00:00Z
    Verlag MDPI AG
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  6. Artikel ; Online: The effects of fruit bagging on residue behavior and dietary risk for four pesticides in apple

    Guofeng Xu / Jiyun Nie / Yonglong Wu / Zhen Yan / Mengliang Ye

    Scientific Reports, Vol 8, Iss 1, Pp 1-

    2018  Band 7

    Abstract: Abstract In this study, the effects of fruit bagging on residue behavior and dietary risk for four pesticides (abamectin, imidacloprid, carbendazim and difenoconazole) in apple were investigated. The dissipation behavior of four pesticides were assessed ... ...

    Abstract Abstract In this study, the effects of fruit bagging on residue behavior and dietary risk for four pesticides (abamectin, imidacloprid, carbendazim and difenoconazole) in apple were investigated. The dissipation behavior of four pesticides were assessed after spraying on three occasions with the first spray at 2 months before harvest and the subsequent sprays at 10-day intervals at recommended doses of 5.4, 45, 135 and 975 g. a.i.ha−1, respectively. The dissipation experiment results demonstrated that apple fruit bagging reduced the initial deposits of four pesticides from 72.2% to 95.3%, prolonged the half-lives from 50.4% to 81.1%. The ultimate residues of abamectin, imidacloprid, carbendazim, and difenoconazole in bagged apple were far below the residues of unbagged apple. The dietary risks of four pesticides were assessed according to the ultimate residues and acceptable daily intakes (ADIs). The hazard quotient (HQ) were 0.013% to 43.415% for different pesticides. Fruit bagging reduced the HQ of four pesticides from 29.7% to 94.8%. Fruit bagging reduced the dietary risk of four pesticides in apple.
    Schlagwörter Fruit Bagging ; Residue Behavior ; Dietary Risk Assessment ; Difenoconazole ; Abamectin ; Medicine ; R ; Science ; Q
    Thema/Rubrik (Code) 910
    Sprache Englisch
    Erscheinungsdatum 2018-09-01T00:00:00Z
    Verlag Nature Portfolio
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  7. Artikel ; Online: Forecasting the incidence of mumps in Chongqing based on a SARIMA model

    Hongfang Qiu / Han Zhao / Haiyan Xiang / Rong Ou / Jing Yi / Ling Hu / Hua Zhu / Mengliang Ye

    BMC Public Health, Vol 21, Iss 1, Pp 1-

    2021  Band 12

    Abstract: Abstract Background Mumps is classified as a class C infection disease in China, and the Chongqing area has one of the highest incidence rates in the country. We aimed to establish a prediction model for mumps in Chongqing and analyze its seasonality, ... ...

    Abstract Abstract Background Mumps is classified as a class C infection disease in China, and the Chongqing area has one of the highest incidence rates in the country. We aimed to establish a prediction model for mumps in Chongqing and analyze its seasonality, which is important for risk analysis and allocation of resources in the health sector. Methods Data on incidence of mumps from January 2004 to December 2018 were obtained from Chongqing Municipal Bureau of Disease Control and Prevention. The incidence of mumps from 2004 to 2017 was fitted using a seasonal autoregressive comprehensive moving average (SARIMA) model. The root mean square error (RMSE) and mean absolute percentage error (MAPE) were used to compare the goodness of fit of the models. The 2018 incidence data were used for validation. Results From 2004 to 2018, a total of 159,181 cases (93,655 males and 65,526 females) of mumps were reported in Chongqing, with significantly more men than women. The age group of 0–19 years old accounted for 92.41% of all reported cases, and students made up the largest proportion (62.83%), followed by scattered children and children in kindergarten. The SARIMA(2, 1, 1) × (0, 1, 1)12 was the best fit model, RMSE and MAPE were 0.9950 and 39.8396%, respectively. Conclusion Based on the study findings, the incidence of mumps in Chongqing has an obvious seasonal trend, and SARIMA(2, 1, 1) × (0, 1, 1)12 model can also predict the incidence of mumps well. The SARIMA model of time series analysis is a feasible and simple method for predicting mumps in Chongqing.
    Schlagwörter Incidence ; Mumps ; SARIMA model ; Chongqing ; Public aspects of medicine ; RA1-1270
    Thema/Rubrik (Code) 310
    Sprache Englisch
    Erscheinungsdatum 2021-02-01T00:00:00Z
    Verlag BMC
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  8. Artikel ; Online: Epidemiological and clinical characteristics of severe hand-foot-and-mouth disease (HFMD) among children

    Yanhao Wang / Han Zhao / Rong Ou / Hua Zhu / Lidan Gan / Zihuan Zeng / Ruizhu Yuan / Huan Yu / Mengliang Ye

    BMC Public Health, Vol 20, Iss 1, Pp 1-

    a 6-year population-based study

    2020  Band 11

    Abstract: Abstract Background Hand-foot-and-mouth disease (HFMD) is considered to be self-limited, however, severe HFMD is a deadly threat for children worldwide, therefore, it is essential to define the clinical and epidemiologic characteristics of children with ... ...

    Abstract Abstract Background Hand-foot-and-mouth disease (HFMD) is considered to be self-limited, however, severe HFMD is a deadly threat for children worldwide, therefore, it is essential to define the clinical and epidemiologic characteristics of children with severe HFMD and identify the risk factors of death. Methods Between 2013 and 2018, children who diagnosed with severe HFMD from Chongqing, China were enrolled in this population-based study. A total of 459 severe HFMD children cases were identified during the study period, including 415 survivors and 44 fatal cases. Demographic, geographical, epidemiological and clinical data of the cases were acquired and analyzed. Results Risk factors of the death because of severe HFMD children included female, aged 1 ~ 3 years, enterovirus 71 infection, falling ill in winter, more than one children in home, being taken care of by grandparents, the caregivers’ education not more than 9 years, having fever more than 3 days, consciousness disorders, general weakness, vomiting, general weakness, abnormal pupillary light reflex, repeated cough, tachypnea, moist rales, white frothy sputum, pink frothy sputum, and cyanosis on lips or the whole body, tachycardia, arrhythmia, cold limbs, pale complexion, weakened pulse. (all p < 0.05). Spatial-temporal analysis detected high-value clusters, the most likely cluster located at rural countries in the northern parts of Chongqing, from January, 2015 to July, 2017. (p < 0.01). Besides, some urban districts were also found high incidence of severe HFMD cases according to the incidence maps. Conclusions The detection of clinical risk factors and the temporal, spatial and socio-demographic distribution epidemiological characteristics of severe HFMD contribute to the timely diagnosis and intervention, the results of this study can be the reference of further clinical and public health practice.
    Schlagwörter Epidemiological characteristics ; Risk factors ; Hand-foot-and-mouth disease (HFMD) ; Children ; Public aspects of medicine ; RA1-1270
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Erscheinungsdatum 2020-05-01T00:00:00Z
    Verlag BMC
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  9. Artikel ; Online: Spatiotemporal Epidemiology of Varicella in Chongqing, China, 2014–2018

    Hua Zhu / Han Zhao / Rong Ou / Qing Zeng / Ling Hu / Hongfang Qiu / Manoj Sharma / Mengliang Ye

    International Journal of Environmental Research and Public Health, Vol 17, Iss 2, p

    2020  Band 662

    Abstract: Although immunization against varicella using vaccines has been proven to be significant and effective in the past decades, varicella remains a major public health concern for many developing countries. Varicella vaccination has not been introduced into ... ...

    Abstract Although immunization against varicella using vaccines has been proven to be significant and effective in the past decades, varicella remains a major public health concern for many developing countries. Varicella vaccination has not been introduced into routine immunization programs in China, and varicella outbreaks have continued to occur. Taking the city of Chongqing, which has a high prevalence of varicella, as an example, this study explored the spatiotemporal epidemiology of varicella. Based on the reported data of varicella cases from 1 January 2014 to 31 December 2018 in Chongqing, hot spots and space-time clusters of varicella were identified using spatial autocorrelation analysis and scan statistics. Within this period, a total of 112,273 varicella cases were reported in Chongqing (average annual incidence: 73.44 per 100,000), including one death. The incidence of varicella showed an increasing trend with significant seasonal peaks, which occurred during April to July and October to January of the following year. The total ratio of male to female patients affected was 1.10:1. Children under the age of 15 and students accounted for the majority of the patient population. The hotspots detected through local spatial autocorrelation analysis, and the most likely clusters identified by scan analysis, were primarily in the main urban districts of Chongqing. The secondary clusters were mostly detected in northeast and southwest Chongqing. There were obvious spatial dependence and spatiotemporal clustering characteristics of varicella in Chongqing from 2014 to 2018. High-risk districts, populations, and peak periods were found in this study, which could be helpful in implementing varicella prevention and control programs, and in adjusting vaccination strategies for the varicella vaccine based on actual conditions.
    Schlagwörter varicella ; epidemiology ; spatial analysis ; spatiotemporal cluster ; chongqing ; Medicine ; R
    Thema/Rubrik (Code) 360
    Sprache Englisch
    Erscheinungsdatum 2020-01-01T00:00:00Z
    Verlag MDPI AG
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  10. Artikel ; Online: What has changed HIV and syphilis infection among men who have sex with men (MSM) in Southwest China

    Yangchang Zhang / Guohui Wu / Rongrong Lu / Wanyuan Xia / Ling Hu / Yang Xiong / Junhao Xie / Qiuhua Yu / Mengliang Ye

    BMC Public Health, Vol 19, Iss 1, Pp 1-

    a comparison of prevalence and behavioural characteristics (2013–2017)

    2019  Band 11

    Abstract: Abstract Background Chongqing reportedly has a large MSM population and a high STI prevalence in previous studies. However, most studies are attributed to independent cross-sectional studies, few studies have investigated trends in the prevalence of ... ...

    Abstract Abstract Background Chongqing reportedly has a large MSM population and a high STI prevalence in previous studies. However, most studies are attributed to independent cross-sectional studies, few studies have investigated trends in the prevalence of syphilis and HIV, as well as behavioural characteristics among MSM using serial surveillance surveys. Methods Data were collected in Chongqing through face-to-face questionnaire interview and laboratory testing in Chongqing. The respondents were recruited among MSM by snowball sampling from May 2013 to December 2017. The self-report questionnaire primarily included socio-demographics, HIV knowledge, and HIV-related behaviour characteristics over the year. Blood specimens were tested to diagnose HIV and syphilis infection by Chongqing CDC. Cochran-Armitage trend test and multivariate logistic regression were conducted to compare the changes in STI prevalence and independent behavioural factors among MSM. Results There were 6568 eligible participants (98.4%). The overall HIV prevalence was 20.5% among MSM in Chongqing, with a decrease from 23.0% in 2013 to 19.2% in 2017. The overall syphilis prevalence was 5.8%, with an increase from 3.2% in 2013 to 6.7% in 2017. The proportion of consistent condom use (CCU) during anal intercourse (46.3 to 57.7%, P<0.001),CCU with regular male partners(47.7 to 59.7%, P<0.001), CCU with casual male partners (51.5 to 62.3%, P<0.001) and drug use during anal intercourse (0.3 to 1.4%, P<0.05) were increasing. By contrast, a significant decrease was reported in the percentage of MSM with more than two regular male partners (66.0 to 21.4%, P<0.001) and more than two casual male partners (38.3 to 20.7%, P<0.001). A significant difference was observed in syphilis infection, testing for HIV antibodies and drug use during anal intercourse in the past years between the HIV-positive and HIV-negative respondents. Conclusion A decreasing trend of HIV prevalence was showed during among MSM from 2013 to 2017 in Chongqing. While ...
    Schlagwörter MSM ; HIV ; Syphilis ; Sexually transmitted infection ; Southwest ; Public aspects of medicine ; RA1-1270
    Thema/Rubrik (Code) 310
    Sprache Englisch
    Erscheinungsdatum 2019-10-01T00:00:00Z
    Verlag BMC
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