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  1. Article ; Online: Effect of Length of Cellulose Nanofibers on Mechanical Reinforcement of Polyvinyl Alcohol

    Mengxia Wang / Xiaran Miao / Hui Li / Chunhai Chen

    Polymers, Vol 14, Iss 128, p

    2022  Volume 128

    Abstract: Cellulose nanofibers (CNF), representing the nano-structured cellulose, have attained an extensive research attention due to their sustainability, biodegradability, nanoscale dimensions, large surface area, unique optical and mechanical performance, etc. ...

    Abstract Cellulose nanofibers (CNF), representing the nano-structured cellulose, have attained an extensive research attention due to their sustainability, biodegradability, nanoscale dimensions, large surface area, unique optical and mechanical performance, etc. Different lengths of CNF can lead to different extents of entanglements or network-like structures through van der Waals forces. In this study, a series of polyvinyl alcohol (PVA) composite films, reinforced with CNF of different lengths, were fabricated via conventional solvent casting technique. CNF were extracted from jute fibers by tuning the dosage of sodium hypochlorite during the TEMPO-mediated oxidation. The mechanical properties and thermal behavior were observed to be significantly improved, while the optical transparency decreased slightly (Tr. > 75%). Interestingly, the PVA/CNF20 nanocomposite films exhibited higher tensile strength of 34.22 MPa at 2 wt% filler loading than the PVA/CNF10 (32.55 MPa) while displayed higher elastic modulus of 482.75 MPa than the PVA/CNF20 films (405.80 MPa). Overall, the findings reported in this study provide a novel, simple and inexpensive approach for preparing the high-performance polymer nanocomposites with tunable mechanical properties, reinforced with an abundant and renewable material.
    Keywords TEMPO-mediated oxidized cellulose nanofibrils ; morphology and dimension ; reinforcement ; polyvinyl alcohol ; Organic chemistry ; QD241-441
    Subject code 620
    Language English
    Publishing date 2022-12-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: IFN-γ mediated neuroinflammation and behaviour abnormality after maternal exposure to low dose mixture of food additives and pesticides

    Linyang Song / Xiaoyi He / Mengxia Wang / Lixia Li / Jing Liu / Guoying Li / Junhua Yang

    Food and Agricultural Immunology, Vol 34, Iss

    2023  Volume 1

    Abstract: ABSTRACTPeople often simultaneously expose to acceptable/tolerable daily intake of food additives and pesticides in daily life. Exposure in adult rodents to acceptable/tolerable daily intake of food additives and pesticides chemical mixtures (AFACM) is ... ...

    Abstract ABSTRACTPeople often simultaneously expose to acceptable/tolerable daily intake of food additives and pesticides in daily life. Exposure in adult rodents to acceptable/tolerable daily intake of food additives and pesticides chemical mixtures (AFACM) is reported to cause health damage. Our recently study reported that AFACM exposure of pregnant mice resulted in neuroinflammation and abnormal emotional behaviours in offspring. Here, we found that neutralising IFN-γ with neutralising antibodies completely blocked the influences induced by maternal AFACM exposure, including the increased IFN-γ level in serum, increased IFN-γ, interleukin-6 and tumour necrosis factor-α levels in prefrontal cortex(PFC) in offspring on postnatal day(PND)7, the abnormal emotional behaviours in offspring on PND56, and the decreased of ATPase phospholipid flippase 8A2(ATP8A2) in the PFC of offspring on PND7. In sum, maternal AFACM exposure induced the PFC neuroinflammation, abnormal emotional behaviours and decreased PFC ATP8A2 expression through increasing systemic IFN-γ in offspring.
    Keywords Brain ; cytokines ; modern diet ; pregnancy ; P4-ATPase ; Agriculture (General) ; S1-972 ; Immunologic diseases. Allergy ; RC581-607
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher Taylor & Francis Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Monolayer Sc2CF2 as a Potential Selective and Sensitive NO2 Sensor

    Kai Cheng / Mengxia Wang / Sihao Wang / Nanshu Liu / Jinke Xu / Han Wang / Yan Su

    ACS Omega, Vol 7, Iss 11, Pp 9267-

    Insight from First-Principles Calculations

    2022  Volume 9275

    Keywords Chemistry ; QD1-999
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher American Chemical Society
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Synthesis and Characterization of Novel Triphenylamine—Containing Electrochromic Polyimides with Benzimidazole Substituents

    Kuangguo Yan / Haiquan Chen / Chenjie Zhu / Zhao Ke / Dongwu Li / Mengxia Wang / Fengna Dai / Youhai Yu

    Molecules, Vol 28, Iss 2029, p

    2023  Volume 2029

    Abstract: Two novel electrochromic aromatic polyimides (named as TPA-BIA-PI and TPA-BIB-PI, respectively) with pendent benzimidazole group were synthesized from 1,2-Diphenyl-N,N′-di-4-aminophenyl-5-amino-benzimidazole and 4-Amino-4′-aminophenyl-4″-1-phenyl- ... ...

    Abstract Two novel electrochromic aromatic polyimides (named as TPA-BIA-PI and TPA-BIB-PI, respectively) with pendent benzimidazole group were synthesized from 1,2-Diphenyl-N,N′-di-4-aminophenyl-5-amino-benzimidazole and 4-Amino-4′-aminophenyl-4″-1-phenyl-benzimidazolyl-phenyl-aniline with 4,4′-(hexafluoroisopropane) phthalic anhydride (6FDA) via two-step polymerization process, respectively. Then, polyimide films were prepared on ITO-conductive glass by electrostatic spraying, and their electrochromic properties were studied. The results showed that due to the π-π* transitions, the maximum UV–Vis absorption bands of TPA-BIA-PI and TPA-BIB-PI films were located at about 314 nm and 346 nm, respectively. A pair of reversible redox peaks of TPA-BIA-PI and TPA-BIB-PI films that were associated with noticeable color changed from original yellow to dark blue and green were observed in the cyclic voltammetry (CV) test. With increasing voltage, new absorption peaks of TPA-BIA-PI and TPA-BIB-PI films emerged at 755 nm and 762 nm, respectively. The switching/bleaching times of TPA-BIA-PI and TPA-BIB-PI films were 13 s/16 s and 13.9 s/9.5 s, respectively, showing that these polyimides can be used as novel electrochromic materials.
    Keywords benzimidazole ; two-step polymerization ; polyimide films ; electrochromic materials ; Organic chemistry ; QD241-441
    Subject code 620
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Synthesis of Superheat-Resistant Polyimides with Enhanced Dielectric Constant by Introduction of Cu(ΙΙ)-Coordination

    Guangtao Qian / Mengjie Hu / Shangying Zhang / Mengxia Wang / Chunhai Chen / Jianan Yao

    Polymers, Vol 12, Iss 2, p

    2020  Volume 442

    Abstract: To achieve polyimide-metal complexes with enhanced properties, 5-amine-2-(5-aminopyridin-2-yl)-1-methyl-benzimidazole (PyMePABZ) that contains stiff 2-(2′-pyridyl)benzimidazole (PyBI) was synthesized and exploited to construct the Cu(ΙΙ)-crosslinked ... ...

    Abstract To achieve polyimide-metal complexes with enhanced properties, 5-amine-2-(5-aminopyridin-2-yl)-1-methyl-benzimidazole (PyMePABZ) that contains stiff 2-(2′-pyridyl)benzimidazole (PyBI) was synthesized and exploited to construct the Cu(ΙΙ)-crosslinked polyimides (Cu-PIs). These Cu-PIs exhibited higher dielectric, thermal, and mechanical properties with an increase in Cu 2+ content. Among them, their dielectric constants (ε rS ) were up to 43% superior to that of the neat PI, glass transition temperatures (T g s) were all over 400 °C, and 5% weight loss temperature (T 5% ) maintained beyond 500 °C. These data indicate that the metal coordination crosslinking provided a useful guide to develop high performance PIs which possess potential application as useful high temperature capacitors.
    Keywords polyimide ; metal coordination crosslinking ; high performance ; Organic chemistry ; QD241-441
    Language English
    Publishing date 2020-02-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: The Interaction of lncRNA XLOC-2222497, AKR1C1, and Progesterone in Porcine Endometrium and Pregnancy

    Tao Su / Haile Yu / Gan Luo / Mengxia Wang / Changfan Zhou / Long Zhang / Bin Hou / Chi Zhang / Min Liu / Dequan Xu

    International Journal of Molecular Sciences, Vol 21, Iss 3232, p

    2020  Volume 3232

    Abstract: The endometrium is an important tissue for pregnancy and plays an important role in reproduction. In this study, high-throughput transcriptome sequencing was performed in endometrium samples of Meishan and Yorkshire pigs on days 18 and 32 of pregnancy. ... ...

    Abstract The endometrium is an important tissue for pregnancy and plays an important role in reproduction. In this study, high-throughput transcriptome sequencing was performed in endometrium samples of Meishan and Yorkshire pigs on days 18 and 32 of pregnancy. Aldo-keto reductase family 1 member C1 (AKR1C1) was found to be a differentially expressed gene, and was identified by quantitative real-time PCR (qRT-PCR) and Western blot. Immunohistochemistry results revealed the cellular localization of the AKR1C1 protein in the endometrium. Luciferase activity assay demonstrated that the AKR1C1 core promoter region was located in the region from -706 to -564, containing two nuclear factor erythroid 2-related factor 2 (NRF2) binding sites (antioxidant response elements, AREs). XLOC-2222497 was identified as a nuclear long non-coding RNA (lncRNA) highly expressed in the endometrium. XLOC-2222497 overexpression and knockdown have an effect on the expression of AKR1C1. Endocrinologic measurement showed the difference in progesterone levels between Meishan and Yorkshire pigs. Progesterone treatment upregulated AKR1C1 and XLOC-2222497 expression in porcine endometrial epithelial cells. In conclusion, transcriptome analysis revealed differentially expressed transcripts during the early pregnancy process. Further experiments demonstrated the interaction of XLOC-2222497/AKR1C1/progesterone in the endometrium and provided new potential targets for pregnancy maintenance and its control.
    Keywords AKR1C1 ; endometrium ; pig ; lncRNA ; progesterone ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
    Subject code 570
    Language English
    Publishing date 2020-05-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: RTN3 Regulates the Expression Level of Chemokine Receptor CXCR4 and is Required for Migration of Primordial Germ Cells

    Haitao Li / Rong Liang / Yanan Lu / Mengxia Wang / Zandong Li

    International Journal of Molecular Sciences, Vol 17, Iss 4, p

    2016  Volume 382

    Abstract: CXCR4 is a crucial chemokine receptor that plays key roles in primordial germ cell (PGC) homing. To further characterize the CXCR4-mediated migration of PGCs, we screened CXCR4-interacting proteins using yeast two-hybrid screening. We identified ... ...

    Abstract CXCR4 is a crucial chemokine receptor that plays key roles in primordial germ cell (PGC) homing. To further characterize the CXCR4-mediated migration of PGCs, we screened CXCR4-interacting proteins using yeast two-hybrid screening. We identified reticulon3 (RTN3), a member of the reticulon family, and considered an apoptotic signal transducer, as able to interact directly with CXCR4. Furthermore, we discovered that the mRNA and protein expression levels of CXCR4 could be regulated by RTN3. We also found that RTN3 altered CXCR4 translocation and localization. Moreover, increasing the signaling of either CXCR4b or RTN3 produced similar PGC mislocalization phenotypes in zebrafish. These results suggested that RTN3 modulates PGC migration through interaction with, and regulation of, CXCR4.
    Keywords primordial germ cells ; RTN3 ; CXCR4 ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
    Language English
    Publishing date 2016-04-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: DNA transposons mediate duplications via transposition-independent and -dependent mechanisms in metazoans

    Shengjun Tan / Huijing Ma / Jinbo Wang / Man Wang / Mengxia Wang / Haodong Yin / Yaqiong Zhang / Xinying Zhang / Jieyu Shen / Danyang Wang / Graham L. Banes / Zhihua Zhang / Jianmin Wu / Xun Huang / Hua Chen / Siqin Ge / Chun-Long Chen / Yong E. Zhang

    Nature Communications, Vol 12, Iss 1, Pp 1-

    2021  Volume 14

    Abstract: Transposons are accepted as evolutionary catalysts but how they do so remains less clear. Analyzing 100 animal genomes finds that terminal inverted repeat-type transposable elements catalyze new gene structures and new genes in animals via both ... ...

    Abstract Transposons are accepted as evolutionary catalysts but how they do so remains less clear. Analyzing 100 animal genomes finds that terminal inverted repeat-type transposable elements catalyze new gene structures and new genes in animals via both transposition-independent and -dependent mechanisms.
    Keywords Science ; Q
    Language English
    Publishing date 2021-07-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Metabolomics insights into the modulatory effects of long-term compound polysaccharide intake in high-fat diet-induced obese rats

    Chen, Mingyi / Biyu Lu / Yuan Li / Yuanyuan Wang / Haihui Zheng / Danmin Zhong / Ziqiong Liao / Mengxia Wang / Fangli Ma / Qiongfeng Liao / Zhiyong Xie

    Nutrition & metabolism. 2018 Dec., v. 15, no. 1

    2018  

    Abstract: BACKGROUND: Polysaccharides can alleviate obesity in mammals; however, studies on mechanism of this alleviation are limited. A few studies have indicated that polysaccharides improve obesity by regulating the metabolism of the body. Therefore, a ... ...

    Abstract BACKGROUND: Polysaccharides can alleviate obesity in mammals; however, studies on mechanism of this alleviation are limited. A few studies have indicated that polysaccharides improve obesity by regulating the metabolism of the body. Therefore, a metabolomics approach, consisting of high resolution nuclear magnetic resonance (NMR) spectroscopy and a multivariate statistical technique, was applied to explore the mechanism of the protective effects of lentinan and Flos Lonicera polysaccharides (LF) on high-fat diet (HFD) induced obesity. METHODS: In this study, rats were randomly divided into three groups: control diet (CD), HFD, and HFD supplemented with a mixture of lentinan and Flos Lonicera polysaccharide. Histopathological and clinical biochemical assessments were also conducted. A combination of a NMR metabolomics study and a multivariable statistical analysis method to distinguish urinary and fecal metabolites was applied. RESULTS: Significant obesity symptoms appeared in HFD rats (for example, significant weight gain, epididymal adipose accumulation and lipid deposition in hepatocytes), which was attenuated in the LF group. Additionally, the HFD induced a reduction of choline, citrate, pyruvate and glycerol and increased the levels of trimethylamine oxide (TMAO) and taurine. Of note, these metabolic disorders were reversed by LF intervention mainly through pathways of energy metabolism, choline metabolism and gut microbiota metabolism. CONCLUSIONS: LF supplementation had a re-balancing effect on the disturbed metabolic pathways in the obese body. The results of this study validate the therapeutic effect of the compound polysaccharide--LF in obesity and described the biochemical and metabolic mechanisms involved.
    Keywords Lonicera ; biochemical pathways ; choline ; citrates ; energy metabolism ; epididymis ; glycerol ; hepatocytes ; high fat diet ; histopathology ; intestinal microorganisms ; lipids ; metabolic diseases ; metabolites ; metabolomics ; nuclear magnetic resonance spectroscopy ; obesity ; polysaccharides ; protective effect ; pyruvic acid ; rats ; statistical analysis ; taurine ; therapeutics ; trimethylamine ; weight gain
    Language English
    Dates of publication 2018-12
    Size p. 8.
    Publishing place BioMed Central
    Document type Article
    ISSN 1743-7075
    DOI 10.1186/s12986-018-0246-2
    Database NAL-Catalogue (AGRICOLA)

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