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  1. Article ; Online: Superior Ophthalmic Vein Thrombosis Associated With Asymptomatic COVID-19 Infection.

    Menke, Bryant A / Ryu, Christine / Chundury, Rao V

    Ophthalmic plastic and reconstructive surgery

    2024  Volume 40, Issue 2, Page(s) e41–e42

    Abstract: Superior ophthalmic vein thrombosis is a rare condition scarcely described in clinical literature with potentially severe consequences including permanent vision loss. This report details the case of a 70-year-old woman who presented with acute binocular ...

    Abstract Superior ophthalmic vein thrombosis is a rare condition scarcely described in clinical literature with potentially severe consequences including permanent vision loss. This report details the case of a 70-year-old woman who presented with acute binocular horizontal diplopia, relative proptosis of the OD by 4 mm, and pain OD. On exam, visual acuity was 20/20 OD and 20/30 OS with full extraocular movements. CT revealed proptosis OD with a thrombosed superior ophthalmic varix. Evaluation for etiology of hypercoagulability was unremarkable, although the patient did have an asymptomatic COVID-19 infection 1 month prior. To the authors' knowledge, this is the first reported case of superior ophthalmic vein thrombosis secondary to an asymptomatic COVID-19 infection.
    MeSH term(s) Female ; Humans ; Aged ; Venous Thrombosis/etiology ; Venous Thrombosis/complications ; COVID-19/complications ; Eye/blood supply ; Exophthalmos/etiology ; Thrombosis ; Diplopia/etiology ; Varicose Veins/complications
    Language English
    Publishing date 2024-03-01
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 632830-1
    ISSN 1537-2677 ; 0740-9303
    ISSN (online) 1537-2677
    ISSN 0740-9303
    DOI 10.1097/IOP.0000000000002540
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Ophthalmic manifestations and management considerations for emerging chemical threats.

    Menke, Bryant A / Ryu, Christine / Justin, Grant A / Chundury, Rao V / Hayek, Brent R / Debiec, Matthew R / Yeh, Steven

    Frontiers in toxicology

    2023  Volume 5, Page(s) 1281041

    Abstract: Chemical agents have been utilized for centuries in warfare and pose a health threat to civilians and military personnel during armed conflict. Despite treaties and regulations against their use, chemical agent exposure remains a threat and measures to ... ...

    Abstract Chemical agents have been utilized for centuries in warfare and pose a health threat to civilians and military personnel during armed conflict. Despite treaties and regulations against their use, chemical agent exposure remains a threat and measures to understand their effects and countermeasures for systemic and organ-specific health are needed. Many of these agents have ocular complications, both acute and chronic. This mini-review focuses on key chemical agents including vesicants (mustards, lewisite), nerve agents (sarin, VX), knockdown gasses (hydrogen cyanide), and caustics (hydrofluoric acid). Their ophthalmic manifestations and appropriate treatment are emphasized. Acute interventions include removal of the source and meticulous decontamination, as well as normalization of pH to 7.2-7.4 if alteration of the ocular pH is observed. Besides vigorous lavage, acute therapies may include topical corticosteroids and non-steroid anti-inflammatory therapies. Appropriate personal protective equipment (PPE) and strict donning and doffing protocols to avoid healthcare provider exposure are also paramount in the acute setting. For more severe disease, corneal transplantation, amniotic membrane graft, and limbal stem cell transplantation may be needed. Orbital surgery may be required in patients in whom cicatricial changes of the ocular surface have developed, leading to eyelid malposition. Multidisciplinary care teams are often required to handle the full spectrum of findings and consequences associated with emerging chemical threats.
    Language English
    Publishing date 2023-10-18
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 2673-3080
    ISSN (online) 2673-3080
    DOI 10.3389/ftox.2023.1281041
    Database MEDical Literature Analysis and Retrieval System OnLINE

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