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Article ; Online: Comment on'' ''Immunophenotypic profile and clinical outcome of monoclonal B-cell lymphocytosis in kidney transplantation'' by Alfano G, Fontana F, Colaci E, et al., Clin Transplant, 2018 Aug;32(8):e13338, doi: 10.1111/ctr.13338, Epub 2018 Aug 26.''.

Merdin, Alparslan

2018 Volume 33, Issue 1, Page(s) e13455

MeSH term(s)	B-Lymphocytes/immunology ; Humans ; Immunophenotyping ; Kidney Transplantation ; Lymphocytosis
Language	English
Publishing date	2018-12-19
Publishing country	Denmark
Document type	Letter ; Comment
ZDB-ID	639001-8
ISSN	1399-0012 ; 0902-0063
ISSN (online)	1399-0012
ISSN	0902-0063
DOI	10.1111/ctr.13455
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Article ; Online: Evaluation of awareness about importance of high fever in leukemia and lymphoma patients receiving chemotherapy among healthcare professionals working in pharmacies other than hospital pharmacies: A survey from a Central Anatolian city.

Mert, Duygu / Merdin, Alparslan

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

2022 Volume 29, Issue 3, Page(s) 543–546

Abstract: Introduction: Pharmacy staff are part of the healthcare delivery. In some cases, the patient goes to the pharmacy before the doctor and asks for a medicine suitable for his own complaint. The aim of this study is to evaluate the awareness about the ... ...

Abstract	Introduction: Pharmacy staff are part of the healthcare delivery. In some cases, the patient goes to the pharmacy before the doctor and asks for a medicine suitable for his own complaint. The aim of this study is to evaluate the awareness about the importance of high fever in patients with leukemia and lymphoma receiving chemotherapy among healthcare professionals working in non-hospital pharmacies. Material and method: The study is a survey study. 140 pharmacy employees working in non-hospital pharmacies in Ankara Province were included in the study. Volunteer participants were included in the study. Seven questions were asked to the participants. Results: About 47.1% of the participants stated that they would advise patients to go immediately to the nearest hospital's emergency department when they presented to the pharmacy and said that they had high fever. It was stated by 56.5% of the participating pharmacy employees that high fever did not pose the same risk for a leukemia or lymphoma patient receiving chemotherapy as it did for a leukemia or lymphoma patient not receiving chemotherapy. Conclusion: In this study, it was found that awareness about importance of high fever in leukemia and lymphoma patients receiving chemotherapy among healthcare professionals working in pharmacies other than hospital pharmacies was not very high. Providing necessary information to the pharmacy personnels and increasing the awareness about importance of high fever in leukemia and lymphoma patients receiving chemotherapy among the non-hospital pharmacy staff might also contribute to the reduction of negativities associated with infections in such patients.
MeSH term(s)	Humans ; Pharmacists ; Delivery of Health Care ; Community Pharmacy Services ; Leukemia/drug therapy ; Lymphoma/drug therapy
Language	English
Publishing date	2022-01-17
Publishing country	England
Document type	Journal Article
ZDB-ID	1330764-2
ISSN	1477-092X ; 1078-1552
ISSN (online)	1477-092X
ISSN	1078-1552
DOI	10.1177/10781552221074045
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Article ; Online: Parasitic Diseases as Differential Diagnosis in the Field of Hematology.

Merdin, Alparslan

Turkiye parazitolojii dergisi

2017 Volume 41, Issue 1, Page(s) 60–61

Language	English
Publishing date	2017
Publishing country	Turkey
Document type	Journal Article
ISSN	2146-3077
ISSN (online)	2146-3077
DOI	10.5152/tpd.2017.5143
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Article ; Online: PREVALENCE OF THROMBOCYTOSIS, THROMBOCYTOPENIA, LYMPHOCYTOSIS AND LYMPHOCYTOPENIA IN PATIENTS WITH LOWER RESPIRATORY TRACT INFECTION AND PATIENTS WITH URINARY TRACT INFECTION.

Mert, Duygu / Merdin, Alparslan

Acta clinica Croatica

2020 Volume 59, Issue 1, Page(s) 63–66

Abstract: There are many reasons for abnormal lymphocyte and platelet counts. In this study, we aimed to assess the prevalence of thrombocytosis, thrombocytopenia, lymphocytosis and lymphocytopenia in patients with lower respiratory tract infection (LRTI) and ... ...

Abstract	There are many reasons for abnormal lymphocyte and platelet counts. In this study, we aimed to assess the prevalence of thrombocytosis, thrombocytopenia, lymphocytosis and lymphocytopenia in patients with lower respiratory tract infection (LRTI) and patients with urinary tract infection (UTI). This retrospective study included 52 LRTI patients and 60 UTI patients. Control group consisted of 70 healthy individuals admitted to the infectiology outpatient unit. No statistically significant relationship was found between the groups of subjects and platelet count. Seven (11.7%) UTI patients and four (7.7%) LRTI patients had lymphocytopenia but there was no statistically significant relationship between the groups of subjects and lymphocyte count. Study results suggested a conclusion that lymphocyte and platelet counts could be within the normal ranges in patients with UTI, as well as in those with LRTI.
MeSH term(s)	Humans ; Lymphocytosis/epidemiology ; Lymphopenia/epidemiology ; Prevalence ; Respiratory Tract Infections/complications ; Respiratory Tract Infections/epidemiology ; Retrospective Studies ; Thrombocytopenia/epidemiology ; Thrombocytosis/epidemiology ; Urinary Tract Infections/complications ; Urinary Tract Infections/epidemiology
Language	English
Publishing date	2020-07-25
Publishing country	Croatia
Document type	Journal Article
ZDB-ID	1478635-7
ISSN	1333-9451 ; 0353-9466
ISSN (online)	1333-9451
ISSN	0353-9466
DOI	10.20471/acc.2020.59.01.08
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Zs.A 5057: Show issues

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Article: Tribal treatment approach to abdominal pain in the Sub-Saharan Tropical Africa.

Birge, Ozer / Merdin, Alparslan

Clinical case reports

2016 Volume 4, Issue 6, Page(s) 611–612

Abstract: There are different primitive tribal treatment ways in the Sub-Saharan Africa. WHO must try more to educate these communities to abandon such harmful treatment ways. ...

Abstract	There are different primitive tribal treatment ways in the Sub-Saharan Africa. WHO must try more to educate these communities to abandon such harmful treatment ways.
Language	English
Publishing date	2016-04-28
Publishing country	England
Document type	Journal Article
ZDB-ID	2740234-4
ISSN	2050-0904
ISSN	2050-0904
DOI	10.1002/ccr3.559
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Article ; Online: Evaluation of hepatitis B virus, hepatitis C virus, and human immunodeficiency virus seroprevalence in patients with diffuse large B cell lymphoma and Hodgkin's lymphoma.

Mert, Duygu / Merdin, Alparslan / Ceken, Sabahat / Dal, Mehmet Sinan / Ertek, Mustafa / Altuntas, Fevzi

Journal of cancer research and therapeutics

2021 Volume 17, Issue 4, Page(s) 951–955

Abstract: Backgrounds: Non-Hodgkin's lymphoma and Hodgkin's lymphomas (HL) are lymphoid neoplasms. Hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) are viruses that could proliferate in lymphoid tissues. These viruses may ... ...

Abstract	Backgrounds: Non-Hodgkin's lymphoma and Hodgkin's lymphomas (HL) are lymphoid neoplasms. Hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV) are viruses that could proliferate in lymphoid tissues. These viruses may cause lymphoproliferative diseases. The aim of this study was to evaluate the seroprevalence of HBV, HCV, and HIV in patients with diffuse large B-cell lymphoma (DLBCL) and HL, to compare the relationship between these two disease groups and to determine the relationship between the three viruses and their characteristics. Materials and methods: The study was a retrospective study. Patients who were followed up in hematology and hepatitis outpatient units between January 01, 2012, and May 01, 2019, were included in the study. Results: A statistically significant relationship was observed between the disease groups in terms of hepatitis B surface antigen (HBsAg), hepatitis B core (HBc) IgG antibody, hepatitis B e antigen (HBeAg), and anti-HBe seropositivities (P = 0.004, P = 0.006, P = 0.041, and P = 0.014, respectively). There was also a statistically significant relationship between the disease groups in terms of anti-HCV seropositivity (P = 0.029). HBsAg, anti-HBc IgG, HBeAg, anti-Hbe, and HCV seropositivity rates were higher in patients with DLBCL than in patients with HL. Conclusion: These findings suggest that there may be a relationship between hepatitis viruses and DLBCL. Evaluation of HBV and HCV infections in these patients before starting treatment is thought to be beneficial in initiating antiviral prophylaxis to prevent reactivation in seropositive cases. In addition, care should be taken for the development of lymphoma in the follow-up of HCV and HBV infections.
MeSH term(s)	Adult ; Antibodies, Viral/blood ; Antibodies, Viral/immunology ; Antigens, Viral/immunology ; Female ; Follow-Up Studies ; HIV/immunology ; HIV Infections/blood ; HIV Infections/complications ; HIV Infections/virology ; Hepacivirus/immunology ; Hepatitis B/blood ; Hepatitis B/complications ; Hepatitis B/virology ; Hepatitis B virus/immunology ; Hepatitis C/blood ; Hepatitis C/complications ; Hepatitis C/virology ; Hodgkin Disease/blood ; Hodgkin Disease/epidemiology ; Hodgkin Disease/immunology ; Hodgkin Disease/virology ; Humans ; Lymphoma, Large B-Cell, Diffuse/blood ; Lymphoma, Large B-Cell, Diffuse/epidemiology ; Lymphoma, Large B-Cell, Diffuse/immunology ; Lymphoma, Large B-Cell, Diffuse/virology ; Male ; Middle Aged ; Prognosis ; Retrospective Studies ; Seroepidemiologic Studies ; Turkey/epidemiology
Chemical Substances	Antibodies, Viral ; Antigens, Viral
Language	English
Publishing date	2021-09-08
Publishing country	India
Document type	Journal Article
ZDB-ID	2187633-2
ISSN	1998-4138 ; 0973-1482
ISSN (online)	1998-4138
ISSN	0973-1482
DOI	10.4103/jcrt.JCRT_465_19
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Article: Chronic total uterine inversion in an adolescent.

Birge, Ozer / Merdin, Alparslan

Clinical case reports

2015 Volume 3, Issue 11, Page(s) 966–967

Abstract: Uterine inversion is rarely seen in adolescents in western countries. But it might be seen in teenagers and adolescents due to poor conditions and early pregnancies in Africa. And early troubleshooting chronic uterine inversion represents an early ... ...

Abstract	Uterine inversion is rarely seen in adolescents in western countries. But it might be seen in teenagers and adolescents due to poor conditions and early pregnancies in Africa. And early troubleshooting chronic uterine inversion represents an early resolution of the problem and allows planning pregnancy without complications.
Language	English
Publishing date	2015-10-21
Publishing country	England
Document type	Journal Article
ZDB-ID	2740234-4
ISSN	2050-0904
ISSN	2050-0904
DOI	10.1002/ccr3.410
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Article ; Online: Five-year period evaluation of isolated agents and their resistance profiles in intensive care unit patients with malignancy.

Mert, Duygu / Muslu, Selda / Merdin, Alparslan / Timuroğlu, Arif / Dirim, Ece / Ünver, Süheyla / Ertek, Mustafa

Journal of infection in developing countries

2020 Volume 14, Issue 8, Page(s) 918–923

Abstract: Introduction: Patients treated in the intensive care unit (ICU) are usually patients who deteriorated health condition and could have longer hospital stay compared to other patients. Hospital infections are more common in ICU patients. The aim of this ... ...

Abstract	Introduction: Patients treated in the intensive care unit (ICU) are usually patients who deteriorated health condition and could have longer hospital stay compared to other patients. Hospital infections are more common in ICU patients. The aim of this study was to evaluate the bacteria and treatment resistance profiles isolated from clinical specimens sent for hospital infections in ICU patients between January 1, 2014 and December 31, 2018. Methodology: Bacteria isolated from various clinical samples sent for hospital infections in hospitalized patients in the Anesthesia and Reanimation Intensive Care Unit were retrospectively analyzed. Results: Culture positivity was detected in 547 of the sent clinical samples. Eighty Gram-positive bacteria, 389 Gram-negative bacteria and 78 fungi infection were identified in a total of 547 positive cultures. In Gram-positive bacteria, 4 MRSA, 6 VRE and 30 MRCoNS were identified as resistant strains. In Gram-negative bacteria, Acinetobacter spp. was the most culture positive strain with the number of 223. Carbapenem resistance was found in 258 of the Gram-negative bacteria and ESBL positivity was found in 44 of the Gram-negative bacteria strains. Conclusions: Gram-negative bacteria were the most frequently isolated strain in samples. Recently, colistin resistance has been increasing in Acinetobacter spp. and the increase in carbapenemase enzyme in Escherichia coli, Pseudomonas and Klebsiella species has increased resistance to carbapenems. Knowing the microorganisms that grow in ICUs and their antibiotic resistance patterns may help to prevent contamination of resistant microorganisms by both appropriate empirical antibiotic treatment and more isolation as well as general hygiene standard precautions.
MeSH term(s)	Acute Disease/epidemiology ; Cross Infection/epidemiology ; Cross Infection/microbiology ; Drug Resistance, Bacterial ; Female ; Fungi/drug effects ; Fungi/isolation & purification ; Gram-Negative Bacteria/drug effects ; Gram-Negative Bacteria/isolation & purification ; Gram-Positive Bacteria/drug effects ; Gram-Positive Bacteria/isolation & purification ; Humans ; Intensive Care Units/statistics & numerical data ; Male ; Neoplasms/epidemiology ; Retrospective Studies
Language	English
Publishing date	2020-08-31
Publishing country	Italy
Document type	Journal Article
ZDB-ID	2394024-4
ISSN	1972-2680 ; 2036-6590
ISSN (online)	1972-2680
ISSN	2036-6590
DOI	10.3855/jidc.12219
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Article ; Online: Evaluation of HBV, HCV, and HIV seroprevalence in patients with plasma cell disorders.

Mert, Duygu / Merdin, Alparslan / Çakar, Merih Kizil / Dal, Mehmet Sinan / Altuntaş, Fevzi

Medicine

2020 Volume 99, Issue 34, Page(s) e21799

Abstract: Hepatitis B (HBV) and hepatitis C (HCV) viruses are hepatotropic and lymphotropic viruses that can proliferate either in lymphocytes and monocytes or hepatocytes.The aim of this study was to evaluate the seroprevalence of HBV, HCV, and human ... ...

Abstract	Hepatitis B (HBV) and hepatitis C (HCV) viruses are hepatotropic and lymphotropic viruses that can proliferate either in lymphocytes and monocytes or hepatocytes.The aim of this study was to evaluate the seroprevalence of HBV, HCV, and human immunodeficiency virus (HIV) in patients with plasma cell disorders. We also aimed to compare patients with plasma cell disorders and chronic lymphocytic leukemia (CLL) in terms of HBV, HCV, and HIV seropositivity.This is a retrospective study. The patients who had patient file in the Multiple Myeloma Outpatient Unit of our hospital and were followed in our outpatient unit between January 1, 2012 and September 15, 2019, with diagnoses of either of the plasma cell disorders were included in the study. In addition, 272 CLL patients who were admitted to the Leukemia Outpatient Unit of our hospital were also enrolled in the study. The 2 disease groups were compared in terms of HBV, HCV, and HIV seropositivity.A statistically significant relationship was found between disease groups according to hepatitis B surface antigen (P < .05). Hepatitis B positivity were found to be more common in CLL patients. There was also a statistically significant relationship between the disease groups in terms of hepatitis B e antigen positivity (P = .001).We found that hepatitis B surface antigen positivity rate in CLL patients was higher than in patients with plasma cell disorders. Seroprevalence of HBV, HCV, and HIV was found to be very low in patients with plasma cell disorders.
MeSH term(s)	Aged ; Comorbidity ; Female ; HIV Infections/blood ; HIV Infections/immunology ; HIV Seroprevalence ; Hepatitis B/blood ; Hepatitis B/epidemiology ; Hepatitis B Antigens/blood ; Hepatitis B Antigens/immunology ; Hepatitis B Core Antigens/blood ; Hepatitis B Core Antigens/immunology ; Hepatitis B Surface Antigens/blood ; Hepatitis B Surface Antigens/immunology ; Hepatitis B e Antigens/blood ; Hepatitis C/epidemiology ; Hepatitis C Antibodies/blood ; Humans ; Immunoglobulin G/blood ; Immunoglobulin M/blood ; Leukemia, Lymphocytic, Chronic, B-Cell/epidemiology ; Male ; Middle Aged ; Multiple Myeloma/epidemiology ; Paraproteinemias/epidemiology ; Plasma Cells/pathology ; Retrospective Studies ; Seroepidemiologic Studies
Chemical Substances	Hepatitis B Antigens ; Hepatitis B Core Antigens ; Hepatitis B Surface Antigens ; Hepatitis B e Antigens ; Hepatitis C Antibodies ; Immunoglobulin G ; Immunoglobulin M
Language	English
Publishing date	2020-08-26
Publishing country	United States
Document type	Comparative Study ; Journal Article ; Observational Study
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000021799
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Article ; Online: A multiple myeloma patient who developed ischemic colitis during lenalidomide treatment: A rare case report.

Batgi, Hikmettullah / Dal, Mehmet Sinan / Merdin, Alparslan / Kızıl Çakar, Merih / Yiğenoğlu, Tuğçe Nur / Altuntaş, Fevzi

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

2020 Volume 26, Issue 6, Page(s) 1499–1500

Abstract: Introduction: Multiple myeloma is a malignant neoplasm of plasma cells. Lenalidomide-dexamethasone treatment is a common treatment regimen used in refractory multiple myeloma.: Case report: We describe the case of a 58-year-old male multiple myeloma ... ...

Abstract	Introduction: Multiple myeloma is a malignant neoplasm of plasma cells. Lenalidomide-dexamethasone treatment is a common treatment regimen used in refractory multiple myeloma. Case report: We describe the case of a 58-year-old male multiple myeloma patient with a history of relapse after six months of autologous stem cell transplantation. The patient had nausea and bloody diarrhea developed during lenalidomide treatment. Discussion: Risk of developing ischemic colitis should be kept in mind in patients receiving lenalidomide which should be discontinued in cases with severe bloody diarrhea of unknown origin.
MeSH term(s)	Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/adverse effects ; Colitis, Ischemic/chemically induced ; Dexamethasone/administration & dosage ; Hematopoietic Stem Cell Transplantation ; Humans ; Lenalidomide/administration & dosage ; Lenalidomide/adverse effects ; Male ; Middle Aged ; Multiple Myeloma/drug therapy ; Neoplasm Recurrence, Local/drug therapy ; Transplantation, Autologous
Chemical Substances	Dexamethasone (7S5I7G3JQL) ; Lenalidomide (F0P408N6V4)
Language	English
Publishing date	2020-02-06
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	1330764-2
ISSN	1477-092X ; 1078-1552
ISSN (online)	1477-092X
ISSN	1078-1552
DOI	10.1177/1078155219900910
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