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  1. Article ; Online: Is It Safe (and When) to Stop Oral Anticoagulation After Ablation for Atrial fibrillation? (Do We Have Enough Evidence to Solve the Dilemma?).

    Merino, José Luis / Tamargo, Juan

    Cardiovascular drugs and therapy

    2021  Volume 35, Issue 6, Page(s) 1191–1204

    MeSH term(s) Administration, Oral ; Anticoagulants/administration & dosage ; Anticoagulants/therapeutic use ; Atrial Fibrillation/therapy ; Catheter Ablation/statistics & numerical data ; Clinical Trials as Topic ; Drug Administration Schedule ; Hemorrhage/chemically induced ; Hemorrhage/prevention & control ; Humans ; Meta-Analysis as Topic ; Practice Guidelines as Topic
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2021-09-07
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 639068-7
    ISSN 1573-7241 ; 0920-3206
    ISSN (online) 1573-7241
    ISSN 0920-3206
    DOI 10.1007/s10557-021-07246-3
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  2. Article ; Online: Tools or Toys? The 20-Year Anniversary of the Nonfluoroscopic Mapping System Dilemma.

    Merino, José Luis

    Revista espanola de cardiologia (English ed.)

    2017  Volume 70, Issue 9, Page(s) 690–693

    Language Spanish
    Publishing date 2017-09
    Publishing country Spain
    Document type Journal Article
    ISSN 1885-5857
    ISSN (online) 1885-5857
    DOI 10.1016/j.rec.2017.05.012
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  3. Article ; Online: Answer to the article: Transonic® and DMed NephroFlow® vascular access flow measurements are not interchangeable.

    Merino, Jose Luis / García, Esther / Varillas-Delgado, David / Domínguez, Patricia / Paraíso, Vicente

    The journal of vascular access

    2023  , Page(s) 11297298231160194

    Language English
    Publishing date 2023-04-21
    Publishing country United States
    Document type Letter
    ZDB-ID 2252820-9
    ISSN 1724-6032 ; 1129-7298
    ISSN (online) 1724-6032
    ISSN 1129-7298
    DOI 10.1177/11297298231160194
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  4. Article ; Online: Current status of reimbursement practices for remote monitoring of cardiac implantable electrical devices across Europe.

    Boriani, Giuseppe / Burri, Haran / Svennberg, Emma / Imberti, Jacopo Francesco / Merino, Josè Luis / Leclercq, Christophe

    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

    2022  Volume 24, Issue 12, Page(s) 1875–1880

    Abstract: Remote monitoring (RM) of cardiac implantable electrical devices (CIEDs) is currently proposed as a standard of care for CIEDs follow-up, as recommended by major cardiology societies worldwide. By detecting a series of relevant device and patient-related ...

    Abstract Remote monitoring (RM) of cardiac implantable electrical devices (CIEDs) is currently proposed as a standard of care for CIEDs follow-up, as recommended by major cardiology societies worldwide. By detecting a series of relevant device and patient-related parameters, RM is a valuable option for early detection of CIEDs' technical issues, as well as changes in parameters related to cardio-respiratory functions. Moreover, RM may allow longer spacing between in-office follow-ups and better organization of in-hospital resources. Despite these potential advantages, resulting in improved patient safety, we are still far from a widespread diffusion of RM across Europe. Reimbursement policies across Europe still show an important heterogeneity and have been considered as an important barrier to full implementation of RM as a standard for the follow-up of all the patients with pacemakers, defibrillators, devices for cardiac resynchronization, or implantable loop recorders. Indeed, in many countries, there are still inertia and unresponsiveness to the request for widespread implementation of RM for CIEDs, although an improvement was found in some countries as compared to years ago, related to the provision of some form of reimbursement. As a matter of fact, the COVID-19 pandemic has promoted an increased use of digital health for connecting physicians to patients, even if digital literacy may be a limit for the widespread implementation of telemedicine. CIEDs have the advantage of making possible RM with an already defined organization and reliable systems for data transmissions that can be easily implemented as a standard of care for present and future cardiology practice.
    Language English
    Publishing date 2022-08-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 1449879-0
    ISSN 1532-2092 ; 1099-5129
    ISSN (online) 1532-2092
    ISSN 1099-5129
    DOI 10.1093/europace/euac118
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    Zs.A 5434: Show issues Location:
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  5. Article ; Online: Spotlight on the 2022 ESC guideline management of ventricular arrhythmias and prevention of sudden cardiac death: 10 novel key aspects.

    Könemann, Hilke / Dagres, Nikolaos / Merino, José Luis / Sticherling, Christian / Zeppenfeld, Katja / Tfelt-Hansen, Jacob / Eckardt, Lars

    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

    2023  Volume 25, Issue 5

    Abstract: Sudden cardiac death and ventricular arrhythmias are a global health issue. Recently, a new guideline for the management of ventricular arrhythmias and prevention of sudden cardiac death has been published by the European Society of Cardiology that ... ...

    Abstract Sudden cardiac death and ventricular arrhythmias are a global health issue. Recently, a new guideline for the management of ventricular arrhythmias and prevention of sudden cardiac death has been published by the European Society of Cardiology that serves as an update to the 2015 guideline on this topic. This review focuses on 10 novel key aspects of the current guideline: As new aspects, public basic life support and access to defibrillators are guideline topics. Recommendations for the diagnostic evaluation of patients with ventricular arrhythmias are structured according to frequently encountered clinical scenarios. Management of electrical storm has become a new focus. In addition, genetic testing and cardiac magnetic resonance imaging significantly gained relevance for both diagnostic evaluation and risk stratification. New algorithms for antiarrhythmic drug therapy aim at improving safe drug use. The new recommendations reflect increasing relevance of catheter ablation of ventricular arrhythmias, especially in patients without structural heart disease or stable coronary artery disease with only mildly impaired ejection fraction and haemodynamically tolerated ventricular tachycardias. Regarding sudden cardiac death risk stratification, risk calculators for laminopathies, and long QT syndrome are now considered besides the already established risk calculator for hypertrophic cardiomyopathy. Generally, 'new' risk markers beyond left ventricular ejection fraction are increasingly considered for recommendations on primary preventive implantable cardioverter defibrillator therapy. Furthermore, new recommendations for diagnosis of Brugada syndrome and management of primary electrical disease have been included. With many comprehensive flowcharts and practical algorithms, the new guideline takes a step towards a user-oriented reference book.
    MeSH term(s) Humans ; Stroke Volume ; Ventricular Function, Left ; Arrhythmias, Cardiac/diagnosis ; Arrhythmias, Cardiac/therapy ; Death, Sudden, Cardiac/etiology ; Death, Sudden, Cardiac/prevention & control ; Heart ; Defibrillators, Implantable
    Language English
    Publishing date 2023-04-26
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 1449879-0
    ISSN 1532-2092 ; 1099-5129
    ISSN (online) 1532-2092
    ISSN 1099-5129
    DOI 10.1093/europace/euad091
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  6. Article ; Online: Chronic Total Occlusion Techniques to Recanalize an Occluded Pulmonary Vein After Atrial Fibrillation Ablation.

    Rivero-Santana, Borja / Jurado-Roman, Alfonso / Jimenez-Valero, Santiago / Galeote, Guillermo / Moreno, Raul / Merino, Jose Luis

    The Journal of invasive cardiology

    2023  Volume 35, Issue 4, Page(s) E223–E224

    Abstract: Cardiac computed tomography (CT) scan was performed in a 69-year-old male with atrial fibrillation radiofrequency ablation who was admitted for transcatheter angioplasty of left inferior pulmonary vein (LIPV) stenosis due to recurrent hemoptysis. CT ... ...

    Abstract Cardiac computed tomography (CT) scan was performed in a 69-year-old male with atrial fibrillation radiofrequency ablation who was admitted for transcatheter angioplasty of left inferior pulmonary vein (LIPV) stenosis due to recurrent hemoptysis. CT showed complete ostial occlusion in the area of the LIPV. Occlusion of the pulmonary vein ostium is a rare complication. We describe the successful use of chronic occlusion techniques in the treatment of this patient.
    MeSH term(s) Male ; Humans ; Aged ; Pulmonary Veins/diagnostic imaging ; Pulmonary Veins/surgery ; Atrial Fibrillation/diagnosis ; Atrial Fibrillation/surgery ; Atrial Fibrillation/complications ; Angioplasty/adverse effects ; Vascular Diseases/surgery ; Constriction, Pathologic/diagnosis ; Constriction, Pathologic/etiology ; Constriction, Pathologic/surgery ; Catheter Ablation/adverse effects
    Language English
    Publishing date 2023-04-01
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1154372-3
    ISSN 1557-2501 ; 1042-3931
    ISSN (online) 1557-2501
    ISSN 1042-3931
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    Zs.MO 272: Show issues
    Zs.MG 31: Show issues

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  7. Article ; Online: Performance assessment of electrode configurations for the estimation of omnipolar electrograms from high density arrays.

    Castells, Francisco / Ruipérez-Campillo, Samuel / Segarra, Izan / Cervigón, Raquel / Casado-Arroyo, Rubén / Merino, José Luis / Millet, José

    Computers in biology and medicine

    2023  Volume 154, Page(s) 106604

    Abstract: Objective: The aim of this study is to propose a method to reduce the sensitivity of the estimated omnipolar electrogram (oEGM) with respect to the angle of the propagation wavefront.: Methods: A novel configuration of cliques taking into account all ...

    Abstract Objective: The aim of this study is to propose a method to reduce the sensitivity of the estimated omnipolar electrogram (oEGM) with respect to the angle of the propagation wavefront.
    Methods: A novel configuration of cliques taking into account all four electrodes of a squared cell is proposed. To test this approach, simulations of HD grids of cardiac activations at different propagation angles, conduction velocities, interelectrode distance and electrogram waveforms are considered.
    Results: The proposed approach successfully provided narrower loops (essentially a straight line) of the electrical field described by the bipole pair with respect to the conventional approach. Estimation of the direction of propagation was improved. Additionally, estimated oEGMs presented larger amplitude, and estimations of the local activation times were more accurate.
    Conclusions: A novel method to improve the estimation of oEGMs in HD grid of electrodes is proposed. This approach is superior to the existing methods and avoids pitfalls not yet resolved.
    Relevance: Robust tools for quantifying the cardiac substrate are crucial to determine with accuracy target ablation sites during an electrophysiological procedure.
    MeSH term(s) Electrocardiography/methods ; Heart/physiology ; Electrodes ; Time Factors
    Language English
    Publishing date 2023-01-25
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 127557-4
    ISSN 1879-0534 ; 0010-4825
    ISSN (online) 1879-0534
    ISSN 0010-4825
    DOI 10.1016/j.compbiomed.2023.106604
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    Zs.A 653: Show issues Location:
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  8. Article ; Online: Edoxaban for the prevention of stroke in patients with atrial fibrillation.

    Cervantes, Carlos Escobar / Merino, José Luis / Barrios, Vivencio

    Expert review of cardiovascular therapy

    2019  Volume 17, Issue 4, Page(s) 319–330

    Abstract: Introduction: Edoxaban is the last direct oral anticoagulant marketed for the prevention of stroke among patients with nonvalvular atrial fibrillation (AF). Areas covered: ENGAGE AF-TIMI 48 was the pivotal clinical trial that led to the approval of ... ...

    Abstract Introduction: Edoxaban is the last direct oral anticoagulant marketed for the prevention of stroke among patients with nonvalvular atrial fibrillation (AF). Areas covered: ENGAGE AF-TIMI 48 was the pivotal clinical trial that led to the approval of edoxaban 60 mg once daily. After the publication of this study, a great number of substudies and post hoc analyses have been published, together with some observational studies. The aim of this review was to update the current evidence about the use of edoxaban in AF patients. Expert opinion: In the ENGAGE AF-TIMI 48 trial, edoxaban 60 mg was noninferior to warfarin for the prevention of stroke or systemic embolism, but significantly reduced the risk of bleeding, major adverse cardiac events and death from cardiovascular causes. The relative efficacy and safety of edoxaban 60 mg compared with warfarin were independent of different clinical conditions, such as prior stroke, age, risk of falls, renal function, hepatic disease, ischemic heart disease, heart failure, valvular heart disease, or cancer. Data about the effectiveness and safety of edoxaban in real-life patients are scarce, but consistent with those of the pivotal clinical trial. Edoxaban seems a cost-effective alternative to warfarin among AF patients with moderate to high thromboembolic risk.
    MeSH term(s) Anticoagulants/therapeutic use ; Atrial Fibrillation/complications ; Clinical Trials as Topic ; Cost-Benefit Analysis ; Factor Xa Inhibitors/pharmacokinetics ; Factor Xa Inhibitors/therapeutic use ; Hemorrhage/chemically induced ; Humans ; Pyridines/pharmacokinetics ; Pyridines/therapeutic use ; Stroke/etiology ; Stroke/prevention & control ; Thiazoles/pharmacokinetics ; Thiazoles/therapeutic use ; Thromboembolism/etiology ; Thromboembolism/prevention & control ; Warfarin/therapeutic use
    Chemical Substances Anticoagulants ; Factor Xa Inhibitors ; Pyridines ; Thiazoles ; Warfarin (5Q7ZVV76EI) ; edoxaban (NDU3J18APO)
    Language English
    Publishing date 2019-03-27
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2192343-7
    ISSN 1744-8344 ; 1477-9072
    ISSN (online) 1744-8344
    ISSN 1477-9072
    DOI 10.1080/14779072.2019.1598263
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  9. Article ; Online: EHRA certification: a 15-year journey of attesting excellence in arrhythmia healthcare.

    Tzeis, Stylianos / Theuns, Dominic A / Earley, Mark / Merino, Jose Luis / Leclercq, Christophe

    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology

    2021  Volume 24, Issue 2, Page(s) 175–178

    MeSH term(s) Arrhythmias, Cardiac/diagnosis ; Arrhythmias, Cardiac/therapy ; Certification ; Delivery of Health Care ; Humans
    Language English
    Publishing date 2021-07-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 1449879-0
    ISSN 1532-2092 ; 1099-5129
    ISSN (online) 1532-2092
    ISSN 1099-5129
    DOI 10.1093/europace/euab181
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  10. Article ; Online: Complicaciones arteriales trombóticas en pacientes hospitalizados con COVID-19. Respuesta a cartas relacionadas.

    Rey, Juan R / Merino, José Luis / Iniesta, Ángel M / Caro-Codón, Juan

    Revista espanola de cardiologia

    2020  Volume 74, Issue 1, Page(s) 116

    Title translation Arterial thrombotic complications in hospitalized patients with COVID-19. Response to related letters.
    Keywords covid19
    Language Spanish
    Publishing date 2020-09-16
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 128925-1
    ISSN 1579-2242 ; 0300-8932
    ISSN (online) 1579-2242
    ISSN 0300-8932
    DOI 10.1016/j.recesp.2020.09.003
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