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Article ; Online: Sarcome de kaposi et myélome multiple: s´agit-il d´une association causée par le HHV-8?

Kahouli, Sophia / Zahid, Hafid / Benkirane, Majid / Messaoudi, Nezha

2020 Volume 36, Page(s) 85

Abstract: Kaposi´s sarcoma is a tumor characterized by purple or brownish lesions affecting the skin. It is most commonly associated with human herpes virus type 8 (HHV-8) infection and may be secondary to malignant hemopathy, including lymphomas. We here report a ...

Title translation	IAssociation between Kaposi´s sarcoma and multiple myeloma: is it caused by HHV-8?
Abstract	Kaposi´s sarcoma is a tumor characterized by purple or brownish lesions affecting the skin. It is most commonly associated with human herpes virus type 8 (HHV-8) infection and may be secondary to malignant hemopathy, including lymphomas. We here report a new case of a very rare combination: Kaposi´s disease-multiple myeloma. The study involved Mr. aged 67 years, treated for Kaposi´s disease in the Department of Dermatology. Serological test for HHV-8 was positive; it was associated with stage I multiple myeloma IgG Lambda with a poor prognosis. We here report this 21
MeSH term(s)	Aged ; Herpesvirus 8, Human/isolation & purification ; Humans ; Male ; Multiple Myeloma/pathology ; Multiple Myeloma/virology ; Neoplasm Staging ; Prognosis ; Sarcoma, Kaposi/pathology ; Sarcoma, Kaposi/virology
Language	French
Publishing date	2020-06-12
Publishing country	Uganda
Document type	Case Reports
ZDB-ID	2514347-5
ISSN	1937-8688 ; 1937-8688
ISSN (online)	1937-8688
ISSN	1937-8688
DOI	10.11604/pamj.2020.36.85.22407
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Article ; Online: Cold agglutinins revealed by abnormalities to the cell blood count: a case report.

Zahid, Hafid / Hadef, Rachid / Labrini, Faycal / Yahyaoui, Anass / Messaoudi, Nezha

The Pan African medical journal

2021 Volume 38, Page(s) 328

Abstract: Cold agglutinin are erythrocyte antibodies which possess the property of agglutinating red blood cells at temperatures of below 37°C, this phenomenon is reversible after heating. This is usually immunoglobulin M (IgM) class. Their pathogenicity is much ... ...

Abstract	Cold agglutinin are erythrocyte antibodies which possess the property of agglutinating red blood cells at temperatures of below 37°C, this phenomenon is reversible after heating. This is usually immunoglobulin M (IgM) class. Their pathogenicity is much more related to their temperature range of activity than their title. As we report in this observation, cold hemagglutination makes it difficult to interpret certain immunological tests such as ABO Rh blood grouping or searching for irregular antibodies (SAI). The discovery of cold agglutinins can be fortuitous revealing itself by disturbances and aberrations in the results of blood count or as part of a suggestive clinical or laboratory table cold hemagglutinin disease. The search for a lymphoid hematological at their diagnosis should be systematic.
MeSH term(s)	Anemia, Hemolytic, Autoimmune/diagnosis ; Anemia, Hemolytic, Autoimmune/immunology ; Blood Cell Count ; Cryoglobulins/immunology ; Humans ; Immunoglobulin M/immunology ; Male ; Middle Aged
Chemical Substances	Cryoglobulins ; Immunoglobulin M ; cold agglutinins
Language	English
Publishing date	2021-04-06
Publishing country	Uganda
Document type	Case Reports
ZDB-ID	2514347-5
ISSN	1937-8688 ; 1937-8688
ISSN (online)	1937-8688
ISSN	1937-8688
DOI	10.11604/pamj.2021.38.328.9100
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Article ; Online: Leucémie à plasmocytes primitive: à propos de 03 cas.

Miloudi, Mouhcine / Messaoudi, Nezha

The Pan African medical journal

2016 Volume 24, Page(s) 167

Abstract: Plasma cell leukemia is a rare hematologic malignancy defined by the presence of more than 20% of leukocyte count plasma cells or by a number of circulating plasma cells greater than 2 × ... ...

Title translation	Primary plasma cell leukemia: about 3 cases.
Abstract	Plasma cell leukemia is a rare hematologic malignancy defined by the presence of more than 20% of leukocyte count plasma cells or by a number of circulating plasma cells greater than 2 × 10
MeSH term(s)	Aged ; Female ; Hospitals, Military ; Humans ; Leukemia, Plasma Cell/diagnosis ; Leukemia, Plasma Cell/pathology ; Leukocyte Count ; Male ; Middle Aged ; Morocco ; Multiple Myeloma/pathology ; Prognosis
Language	French
Publishing date	2016
Publishing country	Uganda
Document type	Case Reports ; Journal Article
ZDB-ID	2514347-5
ISSN	1937-8688 ; 1937-8688
ISSN (online)	1937-8688
ISSN	1937-8688
DOI	10.11604/pamj.2016.24.167.9791
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Article ; Online: Un cas marocain d’érythrophagocytose blastique et LAL T de novo sans anomalie cytogénétique.

Kahouli, Sophia / Zahid, Hafid / Khorassani, Mohamed El / Kabbaj, Saâd El / Benkirane, Majid / Messaoudi, Nezha

The Pan African medical journal

2020 Volume 36, Page(s) 202

Abstract: Erythrophagocytosis by blast cells is due to hyperactivation of blast cells. Erythrophagocytosis is associated with T cell myeloid hemopathies (8;16). This study shows an exceptional case of erythrophagocytosis by blast cells in a patient with acute T- ... ...

Title translation	Erythrophagocytosis by blast cells and de novo T cell LAL without cytogenetic abnormalities in a Moroccan patient.
Abstract	Erythrophagocytosis by blast cells is due to hyperactivation of blast cells. Erythrophagocytosis is associated with T cell myeloid hemopathies (8;16). This study shows an exceptional case of erythrophagocytosis by blast cells in a patient with acute T-lymphoblastic leukemia without cytogenetic abnormalities. We here report the case of A.Z, aged 19 years presenting with febrile syndrome with dizziness and phosphenes, tumor syndrome with amygdala and gingival hypertrophy. Blood count revealed hyperleukocytosis (399.5 G/L), with aregenerative anemia (Hb: 9.3 g/dl) and thrombocytopenia (platelet count: 40 g/L). Myelogram showed 90% of blast cells (MPO-negative) with erythrophagocytosis by blast cells images. Immunophenotyping confirmed T-cell LAL. Cytogenetic analysis was normal. Erythrophagocytosis by blast cells in patients with T-cell LAL appears to be a separate entity, hence the importance of images on diagnosis, prognosis and treatment of T-cell LAL.
MeSH term(s)	Erythrocytes/cytology ; Female ; Fever/etiology ; Humans ; Morocco ; Myelography ; Phagocytosis/physiology ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/diagnosis ; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma/pathology ; Prognosis ; Young Adult
Language	French
Publishing date	2020-07-22
Publishing country	Uganda
Document type	Case Reports
ZDB-ID	2514347-5
ISSN	1937-8688 ; 1937-8688
ISSN (online)	1937-8688
ISSN	1937-8688
DOI	10.11604/pamj.2020.36.202.24477
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Article ; Online: Epidemiology of monoclonal gammopathy in Morocco - A hospital-based study.

Ouzzif, Zohra / Doghmi, Kamal / Messaoudi, Nezha / Bouhsain, Sanae / El Machtani, Samira / Biaz, Asmae / Rachid, Achraf / Dami, Abdallah / Bezza, Ahmed / El Maataoui, Aissam

Cancer reports (Hoboken, N.J.)

2023 Volume 6, Issue 5, Page(s) e1814

Abstract: Background: Monoclonal gammopathies are a group of disorders associated with clonal proliferation of plasma cells that produces a monoclonal protein.: Aims: The main objective of this study was to describe the epidemiological and immunochemical ... ...

Abstract	Background: Monoclonal gammopathies are a group of disorders associated with clonal proliferation of plasma cells that produces a monoclonal protein. Aims: The main objective of this study was to describe the epidemiological and immunochemical characteristics of monoclonal gammopathies diagnosed during 19 years in a Moroccan teaching hospital. Materials and results: This retrospective study enrolled 443 Moroccan patients with monoclonal gammopathy, patients meeting the inclusion and exclusion criteria in at the biochemistry department of Military Hospital in Rabat, the capital of Morocco, from January 2000 to August 2019. Of the 443 enrolled patients, 320 (72.23%) were men and 123 (27.77%) were women. All patients were of Caucasian origin, from 12 Moroccan regions. The patient's samples were collected and subjected to serum protein electrophoresis and serum immunofixation electrophoresis to further characterize the monoclonal protein. The mean ± SD age of the 443 participants was 62.24 ± 13.14 years. Reasons for being admitted to the hospital were as follows, bone pain (41.60%), renal failure (19.08%), alteration of the general condition (12.21%), and anemia (10.69). Plasma cell proliferative disorders in our study were as follows, multiple myeloma (MM) (45.65%), Monoclonal gammopathies of undetermined significance (MGUS) (39.05%), Waldenstrom's macroglobulinemia (5.58%), Lymphoma (2.27% + 1.2%), Chronic Lymphocytic Leukemia (2.48%), Plasma cell leukemia (1.86%), Plasmacytoma (0.62%), POEMS syndrome (0.41%), and Amyloidosis (0.84%). The most frequent isotypes in MM were the IgGκ (62) 36.5%, IgGλ (52) 30.6%, IgAκ (27) 15.9%, and the IgAλ (19) 11.2%. It is also worth noting that Free light chain MM represents 20% of all cases of MM. Conclusions: We found that monoclonal gammopathies are age-related and affects men more than women, also the results of this study point to the delayed diagnosis of monoclonal gammopathies, since most of our patients were diagnosed at the MM stage. The most frequent isotypes were the IgGκ and IgGλ in MM and MGUS, in Waldenström macroglobulinemia were IgMκ and IgMλ and the oligoclonal profile represented only 3.70%.
MeSH term(s)	Male ; Humans ; Female ; Middle Aged ; Aged ; Morocco/epidemiology ; Retrospective Studies ; Paraproteinemias/epidemiology ; Paraproteinemias/diagnosis ; Monoclonal Gammopathy of Undetermined Significance/epidemiology ; Monoclonal Gammopathy of Undetermined Significance/diagnosis ; Multiple Myeloma/diagnosis ; Multiple Myeloma/epidemiology ; Waldenstrom Macroglobulinemia/epidemiology ; Hospitals
Language	English
Publishing date	2023-03-31
Publishing country	United States
Document type	Journal Article
ISSN	2573-8348
ISSN (online)	2573-8348
DOI	10.1002/cnr2.1814
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Article ; Online: Une polyradiculonévrite inflammatoire démyélinisante chronique paranéoplasique secondaire à un lymphome

Jennane, Selim / Hasnaoui, Nawal / Mehdi, Mahtat El / Maaroufi, Hicham El / Messaoudi, Nezha / Mikdame, Mohamed / Doghmi, Kamal

The Pan African medical journal

2020 Volume 36, Page(s) 303

Abstract: We here report a single case of chronic paraneoplastic inflammatory demyelinating polyradiculoneuritis secondary to a nasal natural killer (NK) non-Hodgkin T lymphoma. ...

Title translation	Chronic paraneoplastic inflammatory demyelinating polyradiculoneuritis secondary to nasal natural killer lymphoma.
Abstract	We here report a single case of chronic paraneoplastic inflammatory demyelinating polyradiculoneuritis secondary to a nasal natural killer (NK) non-Hodgkin T lymphoma.
MeSH term(s)	Humans ; Lymphoma, Extranodal NK-T-Cell/complications ; Lymphoma, Extranodal NK-T-Cell/diagnosis ; Lymphoma, Extranodal NK-T-Cell/pathology ; Male ; Middle Aged ; Nose Neoplasms/complications ; Nose Neoplasms/diagnosis ; Nose Neoplasms/pathology ; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating/diagnosis ; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating/etiology
Language	French
Publishing date	2020-08-18
Publishing country	Uganda
Document type	Case Reports
ZDB-ID	2514347-5
ISSN	1937-8688 ; 1937-8688
ISSN (online)	1937-8688
ISSN	1937-8688
DOI	10.11604/pamj.2020.36.303.17772
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Article ; Online: Prise en charge des syndromes myélodysplasiques au Maroc à propos d´une étude mono-centrique.

Maaroufi, Hicham El / Ababou, Mounir / Hammani, Adnane / Ahchouch, Siham / Jennane, Salim / Mahtat, Mehdi / Mikdmae, Mohamed / Messaoudi, Nezha / Doghmi, Kamal

The Pan African medical journal

2020 Volume 37, Page(s) 300

Abstract: We conducted a retrospective descriptive analytical study in the Department of Clinical Haematology at the Mohammed V Military Training Hospital in Rabat over a period of 10 years. This study included 76 patients diagnosed with myelodysplastic syndrome ( ... ...

Title translation	A monocentric study on the management of patients with myelodysplastic syndromes in Morocco.
Abstract	We conducted a retrospective descriptive analytical study in the Department of Clinical Haematology at the Mohammed V Military Training Hospital in Rabat over a period of 10 years. This study included 76 patients diagnosed with myelodysplastic syndrome (MDS) between 2008 and 2018. The average number of cases per year was 7.6. Out of 76 patients, 57% were men and 43% were women. The average age of our study population was 65.75 ± 12.55. The average age was 66.88 ± 13.10. No cases of profession exposed to disease was reported. Ninety-seven point three percent of patients had primary myelodysplastic syndrome and only 2 or 2.7% had myelodysplastic syndrome secondary to chemotherapy. The average time between the first visit and the diagnosis of myelodysplastic syndrome was, on average, 33.6 days ± 51, with a median of 19 days. The IPSS prognostic score was: low risk in 37.4% of cases, intermediate risk 1 in 46.6% of cases, intermediate risk in 12% of cases and high risk in 4% of cases. Thus, 84% of patients had low-risk MDS and 16% had high-risk MDS. Regular monitoring of patients showed many complications such as bleeding in 13% of patients, infections in 8% of cases, secondary hemochromatosis as a result of iterative transfusions in 6.6% of patients and transformation to acute myeloid leukemia in 2.7% of patients. In our study, abstention was the therapeutic choice in 42.1% of patients, transfusion was recommended in 35.5% of patients: red cells in 70% of cases, platelet concentrates in 40% of cases, iron chelators in 25% of transfused patients and EPO in 27% of patients. azacitidine was prescribed in 18% of patients, 50% had low-risk MDS and 50% had high-risk MDS. Bone marrow transplant was the only curative treatment for MDS. It was performed in a single patient with high risk MDS.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/adverse effects ; Azacitidine/administration & dosage ; Blood Transfusion/statistics & numerical data ; Bone Marrow Transplantation/statistics & numerical data ; Female ; Humans ; Leukemia, Myeloid, Acute/epidemiology ; Leukemia, Myeloid, Acute/etiology ; Male ; Middle Aged ; Morocco ; Myelodysplastic Syndromes/epidemiology ; Myelodysplastic Syndromes/etiology ; Myelodysplastic Syndromes/therapy ; Retrospective Studies ; Time Factors ; Treatment Outcome
Chemical Substances	Antineoplastic Agents ; Azacitidine (M801H13NRU)
Language	French
Publishing date	2020-12-02
Publishing country	Uganda
Document type	Case Reports
ZDB-ID	2514347-5
ISSN	1937-8688 ; 1937-8688
ISSN (online)	1937-8688
ISSN	1937-8688
DOI	10.11604/pamj.2020.37.300.20972
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Article: Hemoglobinosis C in Morocco : A report of 111 cas.

Ouzzif, Zhor / El Maataoui, Aissam / Oukhedda, Nadia / Messaoudi, Nezha / Mikdam, Mohamed / Abdellatifi, Mohamed / Doghmi, Kamal

La Tunisie medicale

2018 Volume 95, Issue 12, Page(s) 229–233

Abstract: Background: - Hemoglobin C is a hemoglobin variant encountered worldwide. The regionswith high prevalence are West Africa and South-East Asia.The objective of this study is to report cases of hemoglobin C disease brought together during these last ... ...

Abstract	Background: - Hemoglobin C is a hemoglobin variant encountered worldwide. The regionswith high prevalence are West Africa and South-East Asia.The objective of this study is to report cases of hemoglobin C disease brought together during these last twelve years in the Laboratory of Biochemistry and Toxicology of RabatMilitary Hospital Mohammed V (MHIMV). Methods: - This was a retrospective study including111 cases of hemoglobin C disease collected in the Laboratory of Biochemistry of the MHIMVover the past 12 years. A questionnairewasfulfilledwith the epidemiological data,clinical data and the results of the biological explorations. The screening of the hemoglobin variant in this study included several biochemical (hemoglobin electrophoresis at acid and alkalinepH) and hematological tests. Results: - Sex-ratio was equal to 1,22. The age at the time of diagnosis ranges between 4 and 80years old, with the mean of 38. North-West regions of Morocco seem most affected. The most frequent reasons for prescription of the hemoglobin's studywere: biological abnormalities, splenomegaly and anemic syndrome. Blood smear reveals frequently anisopoikilocytosis and red blood target. The biochemical tests contribute to the diagnosis and reveal various and varied etiological groups: heterozygous A/C (75%),homozygous C/C (8%), double heterozygous S/C (9%),C/β+-thal (6%) andC/O-Arab (2%). Conclusion - The results of the present descriptive study are in line with the literature data. The importance of genetic counseling and the installation of a national card of systematic neonatal tracking seemto be unavoidable.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Blood Protein Electrophoresis ; Child ; Child, Preschool ; Cohort Studies ; Female ; Genetic Testing ; Hematologic Tests ; Hemoglobin C/analysis ; Hemoglobin C/genetics ; Hemoglobin C/metabolism ; Hemoglobin C Disease/blood ; Hemoglobin C Disease/diagnosis ; Hemoglobin C Disease/epidemiology ; Hemoglobin C Disease/genetics ; Humans ; Male ; Middle Aged ; Morocco/epidemiology ; Retrospective Studies ; Young Adult
Chemical Substances	Hemoglobin C (9008-00-8)
Language	English
Publishing date	2018-06-26
Publishing country	Tunisia
Document type	Journal Article
ZDB-ID	128627-4
ISSN	0041-4131
ISSN	0041-4131
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Article: Effect of CYP2C9, VKORC1, CYP4F2, and GGCX gene variants and patient characteristics on acenocoumarol maintenance dose: Proposal for a dosing algorithm for Moroccan patients.

Elkhazraji, Abdelhak / Bouaiti, El Arbi / Boulahyaoui, Hassan / Nahmtchougli, Christiana Philippa / Zahid, Hafid / Bensaid, Mounia / Ibrahimi, Azeddine / Messaoudi, Nezha

Drug discoveries & therapeutics

2018 Volume 12, Issue 2, Page(s) 68–76

Abstract: We investigated the impact of non-genetics factors, and single nucleotide polymorphisms (SNPs) in VKORC1, CYP2C9, CYP4F2, and GGCX on acenocoumarol dosage in Moroccan adult's patients, in order to develop an algorithm to predict acenocoumarol dose for ... ...

Abstract	We investigated the impact of non-genetics factors, and single nucleotide polymorphisms (SNPs) in VKORC1, CYP2C9, CYP4F2, and GGCX on acenocoumarol dosage in Moroccan adult's patients, in order to develop an algorithm to predict acenocoumarol dose for Moroccan patients. Our study consisted of 217 Moroccan patients taking a maintenance dose of acenocoumarol for various indications. The patients were genotyped for VKORC1 -1639 G>A, VKORC1 1173 C>T, CYP2C92, CYP2C93, CYP4F2 1347 G>A and GGCX 12970 C>G SNPs. The statistical analysis was performed using the SPSS software. The age and SNPs in VKORC1 and CYP2C9 were significantly associated with the weekly acenocoumarol dose requirement (p = 0.023, p = 0.0001 and p = 0.001 respectively). There was no association found between the weekly acenocoumarol dose and the CYP4F2 or GGCX variants (p-value > 0.05). Non-parametric analysis confirmed the accumulate effect of variant alleles at VKORC1 -1639 G>A, VKORC1 1173 C>T and CYP2C9 SNPs on the acenocoumarol dose requirement. With 90.24% less dose required for one patient carrying homozygote variant at VKORC1 -1173 (TT) and CYP2C9 x/x haplotype. The multiple linear regression analysis showed that mutation in VKORC1 -1639, VKORC1 1173 SNPs, or in CYP2C9 haplotype reduces the mean acenocoumarol weekly dose to 25.4%, 23.4% and 6.2%, respectively. The R2 for multiple regression analysis final model was found to be 35.9%. In this work we were able to establish the factors influencing interindividual sensitivity to the anticoagulant therapy that can help physicians to predict optimal dose requirement for long term therapy.
MeSH term(s)	Acenocoumarol/administration & dosage ; Acenocoumarol/therapeutic use ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Algorithms ; Carbon-Carbon Ligases/genetics ; Cytochrome P-450 CYP2C9/genetics ; Cytochrome P450 Family 4/genetics ; Drug Dosage Calculations ; Female ; Humans ; Linear Models ; Maintenance Chemotherapy ; Male ; Middle Aged ; Morocco ; Pharmacogenomic Variants ; Polymorphism, Single Nucleotide ; Vitamin K Epoxide Reductases/genetics ; Young Adult
Chemical Substances	CYP2C9 protein, human (EC 1.14.13.-) ; Cytochrome P-450 CYP2C9 (EC 1.14.13.-) ; Cytochrome P450 Family 4 (EC 1.14.14.1) ; CYP4F2 protein, human (EC 1.14.14.78) ; VKORC1 protein, human (EC 1.17.4.4) ; Vitamin K Epoxide Reductases (EC 1.17.4.4) ; Carbon-Carbon Ligases (EC 6.4.-) ; glutamyl carboxylase (EC 6.4.-) ; Acenocoumarol (I6WP63U32H)
Language	English
Publishing date	2018-05-14
Publishing country	Japan
Document type	Journal Article
ISSN	1881-7831
ISSN	1881-7831
DOI	10.5582/ddt.2017.01063
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Article: Prognostic factors predicting overall survival in Moroccan patients with myelodysplastic syndrome.

Jennane, Selim / Amelal, Sanae / El Mehdi, Mahtat / Ahid, Samir / Messaoudi, Nezha / Doghmi, Kamal / Mikdame, Mohammed

La Tunisie medicale

2017 Volume 94, Issue 8-9, Page(s) 541–545

Abstract: Background: Prognostic scores are an indispensable tool in the management of myelodysplastic syndromes.: Aim: Identify prognostic factors influencing overall survival of patients with myelodysplastic syndromes.: Methods: We included all patients ... ...

Abstract	Background: Prognostic scores are an indispensable tool in the management of myelodysplastic syndromes. Aim: Identify prognostic factors influencing overall survival of patients with myelodysplastic syndromes. Methods: We included all patients with myelodysplastic syndromes treated in the clinical hematology department of the military hospital of Rabat (Morocco). Results: Seventy-four patients were included. The sex ratio [M / F] was 1.8. The median age was 65.5 years. The median follow-up was 45 months. The karyotype prognostic was good in 74%. In univariate analysis, prognostic factors influencing overall survival are: Age (p = 0.024), karyotype (p = 0.033), rate of bone marrow blasts (p = 0.002), transfusion dependence (p = 0.002), number of cytopenias (p = 0.001), hemoglobin (p = 0.009) and neutrophil count (p = 0.003). In multivariate analysis the only prognostic factor that influenced overall survival was the karyotype (p = 0.036). Transfusion dependence (p = 0.072) and the rate of marrow blasts (p = 0.107) was close to significance. The WHO Prognostic Scoring System (WPSS), the International Prognostic Scoring System (IPSS) and the Revised International Prognostic Scoring System (RIPSS) influence overall survival with a statistical significance (p <0.001). Conclusion: Our study confirms the prognostic value of the karyotype and validated the WPSS, the IPSS and the RIPSS scores as significant predictors of overall survival in Moroccan patients with myelodysplastic syndromes.
MeSH term(s)	Aged ; Analysis of Variance ; Blood Transfusion ; Female ; Follow-Up Studies ; Humans ; Karyotype ; Male ; Morocco ; Myelodysplastic Syndromes/mortality ; Myelodysplastic Syndromes/pathology ; Myelodysplastic Syndromes/therapy ; Prognosis ; Survival Rate
Language	English
Publishing date	2017-06-21
Publishing country	Tunisia
Document type	Journal Article
ZDB-ID	128627-4
ISSN	0041-4131
ISSN	0041-4131
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