Article ; Online: Human Susceptibility to Influenza Infection and Severe Disease.
Cold Spring Harbor perspectives in medicine
2021 Volume 11, Issue 5
Abstract: Influenza viruses are a persistent threat to global human health. Increased susceptibility to infection and the risk factors associated with progression to severe influenza-related disease are determined by a multitude of viral, host, and environmental ... ...
Abstract | Influenza viruses are a persistent threat to global human health. Increased susceptibility to infection and the risk factors associated with progression to severe influenza-related disease are determined by a multitude of viral, host, and environmental conditions. Decades of epidemiologic research have broadly defined high-risk groups, while new genomic association studies have identified specific host factors impacting an individual's response to influenza. Here, we review and highlight both human susceptibility to influenza infection and the conditions that lead to severe influenza disease. |
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MeSH term(s) | Disease Susceptibility ; Host-Pathogen Interactions ; Humans ; Influenza, Human/physiopathology ; Patient Acuity |
Language | English |
Publishing date | 2021-05-03 |
Publishing country | United States |
Document type | Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review |
ISSN | 2157-1422 |
ISSN (online) | 2157-1422 |
DOI | 10.1101/cshperspect.a038711 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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