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Article ; Online: The effects of force application on the compressive properties of femoral spongious bone.

Metzner, F / Fischer, B / Heyde, C-E / Schleifenbaum, S

2022 Volume 101, Page(s) 105866

Abstract: Background: End artefacts play a major role in uniaxial compression tests with cancellous bone specimens. They lead to misinterpretation of mechanical parameters of bones due to uncontrolled introduction of bending moments into the free ends of ... ...

Abstract	Background: End artefacts play a major role in uniaxial compression tests with cancellous bone specimens. They lead to misinterpretation of mechanical parameters of bones due to uncontrolled introduction of bending moments into the free ends of trabeculae. This work aims to simplify current methods preventing end-artefacts and furthermore to investigate the influence of end artefacts on plateau stress. Methods: 176 cylindrical cancellous bone specimens were taken from human femoral condyles and tested in uniaxial compression. The specimens were divided into 2 groups (direct, end-cap) and compressive modulus, maximum stress, plateau stress, energy absorbtion as well as apparent density were evaluated. Density values are from separate specimens which are immediately adjacent to the mechanical specimen. Findings: All mechanical parameters were significantly higher in the end-cap specimens than in the direct ones by about 30 - 40 %, thus reaching similar differences as the previous studies. Greatest differences between groups were determined for compressive modulus (45 %) and plateau stress (35 %). Energy absorbtion can be explained with great accuracy by plateau stress (P < 0.001; R Interpretation: The end-cap method used here to prevent end artefacts showed variations consistent with the literature when compared to the direct method. Additionally it was shown that the way in which the force is applied to the specimen has a major influence on the failure progression behavior, which was characterized using the plateau stress.
MeSH term(s)	Humans ; Stress, Mechanical ; Bone and Bones ; Femur ; Pressure ; Cancellous Bone ; Bone Density
Language	English
Publishing date	2022-12-21
Publishing country	England
Document type	Journal Article
ZDB-ID	632747-3
ISSN	1879-1271 ; 0268-0033
ISSN (online)	1879-1271
ISSN	0268-0033
DOI	10.1016/j.clinbiomech.2022.105866
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Article: Väterliche Risiko- und Schutzfaktoren für Kindeswohlgefährdung und ihre Berücksichtigung in den deutschlandweit eingesetzten Risikoinventaren.

Metzner, Franka / Pawils, Silke

Praxis der Kinderpsychologie und Kinderpsychiatrie

2021 Volume 70, Issue 2, Page(s) 98–114

Abstract: Paternal Risk and Protective Factors for Endangerment of Child Well-Being and their Consideration in the Risk Inventories Used Throughout ... ...

Title translation	Paternal Risk and Protective Factors for Endangerment of Child Well-Being and their Consideration in the Risk Inventories Used Throughout Germany.
Abstract	Paternal Risk and Protective Factors for Endangerment of Child Well-Being and their Consideration in the Risk Inventories Used Throughout Germany
MeSH term(s)	Adolescent ; Child ; Child Abuse/prevention & control ; Child Health/statistics & numerical data ; Fathers/psychology ; Female ; Germany ; Humans ; Male ; Mothers ; Protective Factors ; Risk Factors
Language	German
Publishing date	2021-02-10
Publishing country	Germany
Document type	Journal Article
ZDB-ID	123711-1
ISSN	0032-7034
ISSN	0032-7034
DOI	10.13109/prkk.2021.70.2.98
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Article ; Online: Biomechanical validation of additively manufactured artificial femoral bones.

Metzner, F / Neupetsch, C / Carabello, A / Pietsch, M / Wendler, T / Drossel, W-G

BMC biomedical engineering

2022 Volume 4, Issue 1, Page(s) 6

Abstract: Replicating the mechanical behavior of human bones, especially cancellous bone tissue, is challenging. Typically, conventional bone models primarily consist of polyurethane foam surrounded by a solid shell. Although nearly isotropic foam components have ... ...

Abstract	Replicating the mechanical behavior of human bones, especially cancellous bone tissue, is challenging. Typically, conventional bone models primarily consist of polyurethane foam surrounded by a solid shell. Although nearly isotropic foam components have mechanical properties similar to cancellous bone, they do not represent the anisotropy and inhomogeneity of bone architecture. To consider the architecture of bone, models were developed whose core was additively manufactured based on CT data. This core was subsequently coated with glass fiber composite. Specimens consisting of a gyroid-structure were fabricated using fused filament fabrication (FFF) techniques from different materials and various filler levels. Subsequent compression tests showed good accordance between the mechanical behavior of the printed specimens and human bone. The unidirectional fiberglass composite showed higher strength and stiffness than human cortical bone in 3-point bending tests, with comparable material behaviors being observed. During biomechanical investigation of the entire assembly, femoral prosthetic stems were inserted into both artificial and human bones under controlled conditions, while recording occurring forces and strains. All of the artificial prototypes, made of different materials, showed analogous behavior to human bone. In conclusion, it was shown that low-cost FFF technique can be used to generate valid bone models and selectively modify their properties by changing the infill.
Language	English
Publishing date	2022-08-04
Publishing country	England
Document type	Journal Article
ISSN	2524-4426
ISSN (online)	2524-4426
DOI	10.1186/s42490-022-00063-1
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Article: Umfrage: Postpartale Depression und psychosoziale Belastungen von Patientinnen in der ambulanten gynäkologischen Versorgung

Metzner, F.

Der Frauenarzt

2013 Volume 54, Issue 1, Page(s) 10

Language	German
Document type	Article
ZDB-ID	80364-9
ISSN	0016-0237
Database	Current Contents Medicine

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Article ; Online: Influence of osteoporosis on the compressive properties of femoral cancellous bone and its dependence on various density parameters.

Metzner, F / Neupetsch, C / Fischer, J-P / Drossel, W-G / Heyde, C-E / Schleifenbaum, S

Scientific reports

2021 Volume 11, Issue 1, Page(s) 13284

Abstract: Data collection of mechanical parameters from compressive tests play a fundamental role in FE modelling of bone tissues or the developing and designing of bone implants, especially referring to osteoporosis or other forms of bone loss. A total of 43 ... ...

Abstract	Data collection of mechanical parameters from compressive tests play a fundamental role in FE modelling of bone tissues or the developing and designing of bone implants, especially referring to osteoporosis or other forms of bone loss. A total of 43 cylindrical samples (Ø8 × 16 mm) were taken from 43 freshly frozen proximal femora using a tenon cutter. All femora underwent BMD measurement and additionally apparent- and relative- and bulk density (ρ
MeSH term(s)	Absorptiometry, Photon ; Aged, 80 and over ; Cancellous Bone/pathology ; Compressive Strength ; Female ; Femur/pathology ; Humans ; Male ; Osteoporosis/pathology ; Stress, Mechanical
Language	English
Publishing date	2021-06-24
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-021-92685-z
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Article: Medizinischer Kinderschutz während des Corona-Lockdowns: Vergleichende Befunde der Kinderschutzfälle aus Kliniken und Ambulanzen in Deutschland.

Heimann, T / Ewert, J / Metzner, F / Sigmund, F / Jud, A / Pawils, S

Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde

2021 Volume 169, Issue 4, Page(s) 346–352

Abstract: Background: There are indications that during the lockdown and the measures of social distancing due to the coronavirus disease 2019 (COVID-19) pandemic, physical and sexual child abuse and neglect may have increased. Additionally, decreased social ... ...

Title translation	Medical child protection during the coronavirus lockdown.
Abstract	Background: There are indications that during the lockdown and the measures of social distancing due to the coronavirus disease 2019 (COVID-19) pandemic, physical and sexual child abuse and neglect may have increased. Additionally, decreased social control may have led to a lower detection rate of child protection cases. Objective: This study aimed to better understand the impact of the lockdown in Germany on the frequency and severity of child abuse and neglect. To do so the quantity and quality of cases of suspected child abuse and neglect in German pediatric departments and outpatient departments for medical child protection were examined. Methods: In May 2020 a total of 343 institutions of medical child protection were invited to fill in a questionnaire with items describing their institution and items depicting cases of child protection in March and April 2019 and 2020 regarding age, form and severity of abuse as well as items to describe particular remarks and ideas for child protection during the pandemic. Results: Out of the 343 pediatric departments and outpatient departments of medical child protection invited, the participation rate was 46%. In this study 81 institutions reported the total cases of suspected child abuse or neglect for both March and April 2019 and 2020. The number of cases dropped from 454 to 387 (-15%) in outpatient child abuse clinics and from 307 to 246 (-20%) in pediatric inpatient departments. Regarding the age of affected children and the form of abuse no significant differences were found. Conclusion: The study found a decrease in reported cases of suspected child abuse and neglect during the lockdown in March and April 2020 compared to 2019. While the results do not show an increase of total child abuse and neglect, as suspected by many professionals, the decrease in reported cases may be explained by a steep increase in unreported cases due to reduced social control.
Language	German
Publishing date	2021-02-16
Publishing country	Germany
Document type	English Abstract ; Journal Article
ZDB-ID	137102-2
ISSN	1433-0474 ; 0026-9298
ISSN (online)	1433-0474
ISSN	0026-9298
DOI	10.1007/s00112-021-01135-7
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Article: Qualifikation von Verwaltungsräten und Vorständen

Metzner, Frank

Zeitschrift für das gesamte Kreditwesen : Pflichtblatt der Frankfurter Wertpapierbörse Vol. 70, No. 14 , p. 692-693

eine Aufgabe für die Sparkassenakademie!?

2017 Volume 70, Issue 14, Page(s) 692–693

Author's details	Frank Metzner
Language	German
Publisher	Knapp
Publishing place	Frankfurt, M
Document type	Article
ZDB-ID	5868-3
ISSN	0341-4019
Database	ECONomics Information System

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Article ; Online: Short-term eye movement desensitization and reprocessing (EMDR) therapy to treat children with posttraumatic stress symptoms after single trauma: A case series.

Lempertz, Daniela / Vasileva, Mira / Brandstetter, Luise / Bering, Robert / Metzner, Franka

Clinical child psychology and psychiatry

2022 Volume 28, Issue 2, Page(s) 450–464

Abstract: Background: Traumatic experiences can lead to posttraumatic stress disorder (PTSD). For young children, even minor, inconspicuous looking events can lead to posttraumatic stress symptoms. Trauma-focused treatment with Eye Movement Desensitization and ... ...

Abstract	Background: Traumatic experiences can lead to posttraumatic stress disorder (PTSD). For young children, even minor, inconspicuous looking events can lead to posttraumatic stress symptoms. Trauma-focused treatment with Eye Movement Desensitization and Reprocessing (EMDR) offers children an age-adapted intervention to help them successfully process traumatic experiences. So far, there has been a lack of well evaluated trauma-focused treatments for young children. Methods: These case series examine the effectiveness of a short-term treatment with EMDR therapy for children showing PTSD symptoms after experiencing a single incident induced trauma. Five children between 5 and 10 years of age who developed PTSD after a single incident trauma received a manualized EMDR treatment for 6 weeks (mean number of sessions: seven including a mean number of EMDR sessions: 3.4). Posttraumatic stress symptoms were assessed prior to treatment, following treatment and at a 3-month follow-up with standardized instruments for caregivers and children. Results: PTSD symptoms decreased for all children after completing the treatment from clinical to non-clinical level. Reductions in vegetative hyperarousal, fears and clinging behaviour were achieved. Furthermore, reductions in the parental stress levels, as well as a recovery of everyday routine and everyday stability were observed. Conclusion: Short-term EMDR treatment appears to be a promising treatment for single incident trauma in young children providing a potentially successful quick and safe psychological treatment for children. Results contribute to the knowledge of feasibility and acceptability of short-term, trauma-focused treatments of children with EMDR. Replication of the results of these case series in larger samples using a randomized controlled design is warranted.
MeSH term(s)	Humans ; Child ; Child, Preschool ; Infant ; Eye Movement Desensitization Reprocessing/methods ; Stress Disorders, Post-Traumatic/therapy ; Stress Disorders, Post-Traumatic/psychology ; Eye Movements ; Treatment Outcome ; Fear
Language	English
Publishing date	2022-04-01
Publishing country	England
Document type	Journal Article
ZDB-ID	1324235-0
ISSN	1461-7021 ; 1359-1045
ISSN (online)	1461-7021
ISSN	1359-1045
DOI	10.1177/13591045221082395
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Article ; Online: Selected mechanical properties of human cancellous bone subjected to different treatments: short-term immersion in physiological saline and acetone treatment with subsequent immersion in physiological saline.

Wang, Fangxing / Metzner, Florian / Zheng, Leyu / Osterhoff, Georg / Schleifenbaum, Stefan

Journal of orthopaedic surgery and research

2022 Volume 17, Issue 1, Page(s) 376

Abstract: Background: Physiological saline (0.9% NaCl) and acetone are extensively used for storage (as well as hydration) and removal of bone marrow, respectively, of cancellous bone during preparation and mechanical testing. Our study aimed to investigate the ... ...

Abstract	Background: Physiological saline (0.9% NaCl) and acetone are extensively used for storage (as well as hydration) and removal of bone marrow, respectively, of cancellous bone during preparation and mechanical testing. Our study aimed to investigate the mechanical properties of cancellous bone subjected to short-term immersion in saline and acetone treatment with subsequent immersion in saline. Methods: Cylindrical samples (Ø6 × 12 mm) were harvested from three positions (left, middle, and right) of 1 thoracic vertebral body, 19 lumbar vertebral bodies, and 5 sacral bones, as well as from 9 femoral heads. All samples were divided into two groups according to the different treatments, (i) samples from the left and middle sides were immersed in saline at 4℃ for 43 h (saline-immersed group, n = 48); (ii) samples from the respective right side were treated with a combination of acetone and ultrasonic bath (4 h), air-dried at room temperature (21℃, 15 h), and then immersed in saline at room temperature (21℃, 24 h) (acetone and saline-treated group, n = 38). All samples were subjected, both before and after treatment, to a non-destructive compression test with a strain of 0.45%, and finally destructive tests with a strain of 50%. Actual density (ρ Results: Based on visual observation, a combination of acetone and ultrasonic bath for 4 h failed to completely remove bone marrow from cancellous bone samples. The mean values of ρ Conclusion: Short-term storage in physiological saline is an appropriate choice and has no effect on the E
MeSH term(s)	Acetone ; Biomechanical Phenomena ; Bone Density ; Cancellous Bone ; Humans ; Immersion ; Lumbar Vertebrae/physiology ; Saline Solution ; Stress, Mechanical ; Thoracic Vertebrae
Chemical Substances	Saline Solution ; Acetone (1364PS73AF)
Language	English
Publishing date	2022-08-06
Publishing country	England
Document type	Journal Article
ZDB-ID	2252548-8
ISSN	1749-799X ; 1749-799X
ISSN (online)	1749-799X
ISSN	1749-799X
DOI	10.1186/s13018-022-03265-4
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Article ; Online: The role of bone marrow on the mechanical properties of trabecular bone: a systematic review.

Wang, Fangxing / Metzner, Florian / Osterhoff, Georg / Zheng, Leyu / Schleifenbaum, Stefan

Biomedical engineering online

2022 Volume 21, Issue 1, Page(s) 80

Abstract: Background: Accurate evaluation of the mechanical properties of trabecular bone is important, in which the internal bone marrow plays an important role. The aim of this systematic review is to investigate the roles of bone marrow on the mechanical ... ...

Abstract	Background: Accurate evaluation of the mechanical properties of trabecular bone is important, in which the internal bone marrow plays an important role. The aim of this systematic review is to investigate the roles of bone marrow on the mechanical properties of trabecular bone to better support clinical work and laboratory research. Methods: A systematic review of the literature published up to June 2022 regarding the role of bone marrow on the mechanical properties of trabecular bone was performed, using PubMed and Web of Science databases. The journal language was limited to English. A total of 431 articles were selected from PubMed (n = 186), Web of Science (n = 244) databases, and other sources (n = 1). Results: After checking, 38 articles were finally included in this study. Among them, 27 articles discussed the subject regarding the hydraulic stiffening of trabecular bone due to the presence of bone marrow. Nine of them investigated the effects of bone marrow on compression tests with different settings, i.e., in vitro experiments under unconfined and confined conditions, and computer model simulations. Relatively few controlled studies reported the influence of bone marrow on the shear properties of trabecular bone. Conclusion: Bone marrow plays a non-neglectable role in the mechanical properties of trabecular bone, its contribution varies depending on the different loading types and test settings. To obtain the mechanical properties of trabecular bone comprehensively and accurately, the solid matrix (trabeculae) and fluid-like component (bone marrow) should be considered in parallel rather than tested separately.
MeSH term(s)	Cancellous Bone ; Bone Marrow ; Computer Simulation ; Databases, Factual ; Language
Language	English
Publishing date	2022-11-23
Publishing country	England
Document type	Systematic Review ; Journal Article ; Review
ZDB-ID	2084374-4
ISSN	1475-925X ; 1475-925X
ISSN (online)	1475-925X
ISSN	1475-925X
DOI	10.1186/s12938-022-01051-1
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