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Article ; Online: Pulmonary Embolism: An Update Based on the Revised AWMF-S2k Guideline.

Opitz, Christian F / Meyer, F Joachim

2024 Volume 44, Issue 2, Page(s) 111–118

Abstract: Pulmonary embolism (PE) is the third most common acute cardiovascular disease. The risk of PE increases with age and mortality is high. Patients are stratified into hemodynamically stable versus unstable patients, as this has important implications for ... ...

Abstract	Pulmonary embolism (PE) is the third most common acute cardiovascular disease. The risk of PE increases with age and mortality is high. Patients are stratified into hemodynamically stable versus unstable patients, as this has important implications for diagnosis and therapy. Since clinical signs and symptoms of acute PE are nonspecific, the clinical likelihood of PE is estimated to guide diagnostic pathways. D-dimer testing is performed in hemodynamically stable patients with low or intermediate probability of PE and the visualization of thromboembolism and its sequelae is commonly achieved with computed tomography pulmonary angiography (CTPA), supplemented by ultrasound techniques. With confirmed PE, another risk stratification estimates disease severity and defines intensity and setting of the ensuing treatment. The therapeutic spectrum ranges from outpatient treatment with initial oral anticoagulation to thrombolytic or interventional treatment in the intensive care unit or catheterization laboratory. In single cases, even acute surgical thrombectomy is attempted.
MeSH term(s)	Pulmonary Embolism/diagnosis ; Pulmonary Embolism/therapy ; Humans ; Practice Guidelines as Topic ; Fibrin Fibrinogen Degradation Products/analysis ; Anticoagulants/therapeutic use ; Computed Tomography Angiography ; Thrombolytic Therapy/methods
Chemical Substances	fibrin fragment D ; Fibrin Fibrinogen Degradation Products ; Anticoagulants
Language	English
Publishing date	2024-04-30
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	801512-0
ISSN	2567-5761 ; 0720-9355
ISSN (online)	2567-5761
ISSN	0720-9355
DOI	10.1055/s-0044-1779011
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Article ; Online: Post-Pulmonary Embolism Syndrome: An Update Based on the Revised AWMF-S2k Guideline.

Meyer, F Joachim / Opitz, Christian

Hamostaseologie

2024 Volume 44, Issue 2, Page(s) 128–134

Abstract: In survivors of acute pulmonary embolism (PE), the post-PE syndrome (PPES) may occur. In PPES, patients typically present with persisting or progressive dyspnea on exertion despite 3 months of therapeutic anticoagulation. Therefore, a structured follow- ... ...

Abstract	In survivors of acute pulmonary embolism (PE), the post-PE syndrome (PPES) may occur. In PPES, patients typically present with persisting or progressive dyspnea on exertion despite 3 months of therapeutic anticoagulation. Therefore, a structured follow-up is warranted to identify patients with chronic thromboembolic pulmonary disease (CTEPD) with normal pulmonary pressure or chronic thromboembolic pulmonary hypertension (CTEPH). Both are currently understood as a dual vasculopathy, that is, secondary arterio- and arteriolopathy, affecting the large and medium-sized pulmonary arteries as well as the peripheral vessels (diameter < 50 µm). The follow-up algorithm after acute PE commences with identification of clinical symptoms and risk factors for CTEPH. If indicated, a stepwise performance of echocardiography, ventilation-perfusion scan (or alternative imaging), N-terminal prohormone of brain natriuretic peptide (NT-proBNP) level, cardiopulmonary exercise testing, and pulmonary artery catheterization with angiography should follow. CTEPH patients should be treated in a multidisciplinary center with adequate experience in the complex therapeutic options, comprising pulmonary endarterectomy, balloon pulmonary angioplasty, and pharmacological interventions.
MeSH term(s)	Pulmonary Embolism/therapy ; Pulmonary Embolism/diagnosis ; Pulmonary Embolism/complications ; Humans ; Syndrome ; Practice Guidelines as Topic ; Hypertension, Pulmonary/diagnosis ; Hypertension, Pulmonary/therapy ; Hypertension, Pulmonary/etiology ; Germany ; Cardiology/standards
Language	English
Publishing date	2024-03-26
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	801512-0
ISSN	2567-5761 ; 0720-9355
ISSN (online)	2567-5761
ISSN	0720-9355
DOI	10.1055/a-2229-4190
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Article: Post–Pulmonary Embolism Syndrome: An Update Based on the Revised AWMF-S2k Guideline

Meyer, F. Joachim / Opitz, Christian

Hämostaseologie

2024

Abstract	In survivors of acute pulmonary embolism (PE), the post-PE syndrome (PPES) may occur. In PPES, patients typically present with persisting or progressive dyspnea on exertion despite 3 months of therapeutic anticoagulation. Therefore, a structured follow-up is warranted to identify patients with chronic thromboembolic pulmonary disease (CTEPD) with normal pulmonary pressure or chronic thromboembolic pulmonary hypertension (CTEPH). Both are currently understood as a dual vasculopathy, that is, secondary arterio- and arteriolopathy, affecting the large and medium-sized pulmonary arteries as well as the peripheral vessels (diameter < 50 µm). The follow-up algorithm after acute PE commences with identification of clinical symptoms and risk factors for CTEPH. If indicated, a stepwise performance of echocardiography, ventilation–perfusion scan (or alternative imaging), N-terminal prohormone of brain natriuretic peptide (NT-proBNP) level, cardiopulmonary exercise testing, and pulmonary artery catheterization with angiography should follow. CTEPH patients should be treated in a multidisciplinary center with adequate experience in the complex therapeutic options, comprising pulmonary endarterectomy, balloon pulmonary angioplasty, and pharmacological interventions.
Keywords	pulmonary embolism ; chronic thromboembolic pulmonary hypertension ; chronic thromboembolic pulmonary disease ; pulmonary endarterectomy ; balloon pulmonary angioplasty
Language	English
Publishing date	2024-03-26
Publisher	Georg Thieme Verlag KG
Publishing place	Stuttgart ; New York
Document type	Article
ZDB-ID	801512-0
ISSN	2567-5761 ; 0720-9355
ISSN (online)	2567-5761
ISSN	0720-9355
DOI	10.1055/a-2229-4190
Database	Thieme publisher's database

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Article ; Online: Challenges, obstacles, and unknowns in implementing principles of modern intensive care medicine in low-resource settings: an insider's perspective.

Kovacevic, Pedja / Meyer, F Joachim / Gajic, Ognjen

Intensive care medicine

2023 Volume 50, Issue 1, Page(s) 141–143

MeSH term(s)	Humans ; Critical Care ; Health Resources
Language	English
Publishing date	2023-12-14
Publishing country	United States
Document type	Editorial
ZDB-ID	80387-x
ISSN	1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
ISSN (online)	1432-1238
ISSN	0340-0964 ; 0342-4642 ; 0935-1701
DOI	10.1007/s00134-023-07270-x
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Zs.A 1089: Show issues

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Book: Physiotherapie in der Inneren Medizin

Göhring, Hannelore / Meyer, Franz Joachim / Hüter-Becker, Antje

(Physiolehrbuch : Praxis)

2009

Author's details	Hrsg. Antje Hüter-Becker ... Autorin: Hannelore Göhring. Mit einem Beitr. von F. Joachim Meyer
Series title	Physiolehrbuch : Praxis
Keywords	Innere Krankheit ; Physikalische Therapie
Subject	Physiotherapie ; Innere Erkrankung
Language	German
Size	IX, 153 S. : Ill., graph. Darst.
Edition	2. Aufl.
Publisher	Thieme
Publishing place	Stuttgart u.a.
Publishing country	Germany
Document type	Book
Old title	1. Aufl. u.d.T. Göhring, Hannelore: Physiotherapie in der Inneren Medizin
HBZ-ID	HT016042924
ISBN	978-3-13-129472-2 ; 3-13-129472-8
Database	Catalogue ZB MED Medicine, Health

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Shelf mark	Loan status	Location
2009 A 4489	order for loan	Magazin

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Journal ; Collection: Kodierleitfaden für die Intensivmedizin

Meyer, Franz Joachim / Radeleff, Jannis / Thalheimer, Markus

praxisrelevante Erläuterungen der spezifisch intensivmedizinischen Kodierung

(Praxiswissen Abrechnung)

2008

Title variant	praxisrelevante Erläuterungen der Kodierung der internistischen Intensivmedizin
Author's details	Franz Joachim Meyer ; Jannis Radeleff ; Markus Thalheimer
Series title	Praxiswissen Abrechnung
Keywords	Intensivmedizin ; Stationäre Behandlung ; Diagnosis-related-groups-Konzept ; Diagnosenschlüssel
Subject	Diagnosenschema ; Diagnoseschlüssel ; DRG-Konzept ; DRG-System ; Stationäre Versorgung ; Stationäre ärztliche Versorgung ; Stationäre Therapie ; Stationäre Krankenversorgung
Subject code	616.028012 ; 616.02805
Language	German
Dates of publication	Aufl. 1.2008 -
Size	17 cm
Publisher	medhochzwei ; Medizificon-Verl
Publishing place	Heidelberg ; Mannheim ; Frankfurt, M
Publishing country	Germany
Document type	Journal ; Collection (display volumes)
ZDB-ID	2533869-9
Database	Catalogue ZB MED Medicine, Health

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Se 2315

Holdings: Aufl. 3.2010 - 15.2022

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Article ; Online: Using Machine Learning-Based Algorithms to Identify and Quantify Exercise Limitations in Clinical Practice: Are We There Yet?

Schwendinger, Fabian / Biehler, Ann-Kathrin / Nagy-Huber, Monika / Knaier, Raphael / Roth, Volker / Dumitrescu, Daniel / Meyer, F Joachim / Hager, Alfred / Schmidt-Trucksäss, Arno

Medicine and science in sports and exercise

2023 Volume 56, Issue 2, Page(s) 159–169

Abstract: Introduction: Well-trained staff is needed to interpret cardiopulmonary exercise tests (CPET). We aimed to examine the accuracy of machine learning-based algorithms to classify exercise limitations and their severity in clinical practice compared with ... ...

Abstract	Introduction: Well-trained staff is needed to interpret cardiopulmonary exercise tests (CPET). We aimed to examine the accuracy of machine learning-based algorithms to classify exercise limitations and their severity in clinical practice compared with expert consensus using patients presenting at a pulmonary clinic. Methods: This study included 200 historical CPET data sets (48.5% female) of patients older than 40 yr referred for CPET because of unexplained dyspnea, preoperative examination, and evaluation of therapy progress. Data sets were independently rated by experts according to the severity of pulmonary-vascular, mechanical-ventilatory, cardiocirculatory, and muscular limitations using a visual analog scale. Decision trees and random forests analyses were calculated. Results: Mean deviations between experts in the respective limitation categories ranged from 1.0 to 1.1 points (SD, 1.2) before consensus. Random forests identified parameters of particular importance for detecting specific constraints. Central parameters were nadir ventilatory efficiency for CO 2 , ventilatory efficiency slope for CO 2 (pulmonary-vascular limitations); breathing reserve, forced expiratory volume in 1 s, and forced vital capacity (mechanical-ventilatory limitations); and peak oxygen uptake, O 2 uptake/work rate slope, and % change of the latter (cardiocirculatory limitations). Thresholds differentiating between different limitation severities were reported. The accuracy of the most accurate decision tree of each category was comparable to expert ratings. Finally, a combined decision tree was created quantifying combined system limitations within one patient. Conclusions: Machine learning-based algorithms may be a viable option to facilitate the interpretation of CPET and identify exercise limitations. Our findings may further support clinical decision making and aid the development of standardized rating instruments.
MeSH term(s)	Humans ; Lung ; Exercise Test ; Respiratory Function Tests ; Dyspnea/etiology ; Algorithms ; Exercise Tolerance
Language	English
Publishing date	2023-09-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	603994-7
ISSN	1530-0315 ; 0195-9131 ; 0025-7990
ISSN (online)	1530-0315
ISSN	0195-9131 ; 0025-7990
DOI	10.1249/MSS.0000000000003293
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Article ; Online: Erratum: S2k-Leitlinie Nichtinvasive Beatmung als Therapie der akuten respiratorischen Insuffizienz.

Westhoff, Michael / Neumann, Peter / Geiseler, Jens / Bickenbach, Johannes / Arzt, Michael / Bachmann, Martin / Braune, Stephan / Delis, Sandra / Dellweg, Dominic / Dreher, Michael / Dubb, Rolf / Fuchs, Hans / Hämäläinen, Nina / Heppner, Hans / Kluge, Stefan / Kochanek, Matthias / Lepper, Philipp M / Meyer, F Joachim / Neumann, Bernhard /

Putensen, Christian / Schimandl, Dorit / Schönhofer, Bernd / Schreiter, Dierk / Walterspacher, Stephan / Windisch, Wolfram

Pneumologie (Stuttgart, Germany)

2023

Title translation	Non-invasive Mechanical Ventilation in Acute Respiratory Failure. Clinical Practice Guidelines - on behalf of the German Society of Pneumology and Ventilatory Medicine.
Language	German
Publishing date	2023-11-07
Publishing country	Germany
Document type	Journal Article ; Published Erratum
ZDB-ID	607630-0
ISSN	1438-8790 ; 0934-8387
ISSN (online)	1438-8790
ISSN	0934-8387
DOI	10.1055/a-2196-9136
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Uh II Zs.142: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Zs.MO 54: Show issues

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Article ; Online: S2k-Leitlinie Nichtinvasive Beatmung als Therapie der akuten respiratorischen Insuffizienz.

Putensen, Christian / Schimandl, Dorit / Schönhofer, Bernd / Schreiter, Dierk / Walterspacher, Stephan / Windisch, Wolfram

Pneumologie (Stuttgart, Germany)

2023

Abstract: The guideline update outlines the advantages as well as the limitations of NIV in the treatment of acute respiratory failure in daily clinical practice and in different indications.Non-invasive ventilation (NIV) has a high value in therapy of hypercapnic ...

Title translation	Non-invasive Mechanical Ventilation in Acute Respiratory Failure. Clinical Practice Guidelines - on behalf of the German Society of Pneumology and Ventilatory Medicine.
Abstract	The guideline update outlines the advantages as well as the limitations of NIV in the treatment of acute respiratory failure in daily clinical practice and in different indications.Non-invasive ventilation (NIV) has a high value in therapy of hypercapnic acute respiratory failure, as it significantly reduces the length of ICU stay and hospitalization as well as mortality.Patients with cardiopulmonary edema and acute respiratory failure should be treated with continuous positive airway pressure (CPAP) and oxygen in addition to necessary cardiological interventions. This should be done already prehospital and in the emergency department.In case of other forms of acute hypoxaemic respiratory failure with only mild or moderately disturbed gas exchange (PaO
Language	German
Publishing date	2023-10-13
Publishing country	Germany
Document type	English Abstract ; Journal Article
ZDB-ID	607630-0
ISSN	1438-8790 ; 0934-8387
ISSN (online)	1438-8790
ISSN	0934-8387
DOI	10.1055/a-2148-3323
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Article: Diagnostik und Therapie der Rechtsherzinsuffizienz

Borst, Mathias M. / Meyer, F. Joachim

Kardiologie up2date

2009 Volume 5, Issue 02, Page(s) 123–138

Abstract: Right heart failure may be due to increased afterload caused by ... pulmonary hypertension, increased volume load as in valvular incompetence, ... myocardial ischemia, and cardiomyopathy. The clinical consequences of those ...

Abstract	Right heart failure may be due to increased afterload caused by pulmonary hypertension, increased volume load as in valvular incompetence, myocardial ischemia, and cardiomyopathy. The clinical consequences of those various disease entities are rather homogenous, venous congestion being the key symptom. The diagnosis is based on clinical findings and echocardiography. Right ventricular Tei-index and TAPSE (tricuspid annular plane systolic excursion) are easily obtained measures of right ventricular contractile function. Brain natriuretic peptide is helpful to follow changes in right ventricular dysfunction during therapy. Treatment of right heart failure aims at the correction of the underlying condition, especially if underlying pulmonary disease can be improved. Unifying principles are reduction of excessive pre- and afterload, improved myocardial oxygen delivery and correction of hypercapnia and acidosis, e.g. by ventilatory support. Diuretic therapy must avoid volume depletion resulting in renal failure, whereas volume substitution should be done cautiously. Specific pulmonary vasodilators are indicated only in pulmonary arterial hypertension (PAH) and in inoperable chronic thromboembolic pulmonary hypertension (CTEPH). The standard medical treatment of left heart failure is not generally suitable for right heart dysfunction, except if secondary to left heart disease. In many instances, an interdisciplinary approach to right heart failure is needed, involving the expertise both of the cardiologist and the pulmonologist.
Language	German
Publishing date	2009-06-01
Publishing place	Stuttgart ; New York
Document type	Article
ZDB-ID	2187683-6
ISSN	1860-3513 ; 1611-6534
ISSN (online)	1860-3513
ISSN	1611-6534
DOI	10.1055/s-0029-1214785
Database	Thieme publisher's database

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