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  1. Article: Cobalt- or rhodium-catalyzed synthesis of 1,2-dihydrophosphete oxides

    Xu, Shengbo / Mi, Ruijie / Zheng, Guangfan / Li, Xingwei

    Chemical science

    2024  Volume 15, Issue 16, Page(s) 6012–6021

    Abstract: A highly stereo- and chemoselective intermolecular coupling of diverse heterocycles with dialkynylphosphine oxides has been ... ...

    Abstract A highly stereo- and chemoselective intermolecular coupling of diverse heterocycles with dialkynylphosphine oxides has been realized
    Language English
    Publishing date 2024-03-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2559110-1
    ISSN 2041-6539 ; 2041-6520
    ISSN (online) 2041-6539
    ISSN 2041-6520
    DOI 10.1039/d4sc00649f
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Expression and prognosis analysis of TBX2 subfamily in human lung carcinoma.

    Mi, Rui / Wang, Qiubo / Liu, Qingyang / Jiang, Fengying / Ji, Yuan

    Discover. Oncology

    2024  Volume 15, Issue 1, Page(s) 51

    Abstract: Purpose: Lung cancer has a high morbidity and mortality rate of all cancers worldwide. Therefore, there is an urgent need for reliable cancer markers for diagnosis and prognosis of patients with lung cancer.: Methods: In this study, we used the ... ...

    Abstract Purpose: Lung cancer has a high morbidity and mortality rate of all cancers worldwide. Therefore, there is an urgent need for reliable cancer markers for diagnosis and prognosis of patients with lung cancer.
    Methods: In this study, we used the bioinformatics database to compare the expression of the TBX2 subfamily at the transcriptional and protein levels in non-small cell lung cancer. Then, to confirm our bioinformatics analysis above, we used western bloting to determine the expression of TBX2, TBX3, TBX4 and TBX5 in human lung squamous carcinoma cell lines. Besides, low expression of TBX2 subfamily predicted a poor prognosis of patients with lung cancer. Finally, The methylation database was used to explore the relationship between the low expression of TBX2 subfamily and methylation of gene promoter region.
    Results: Our data showed a significant decrease of TBX2 subfamily expression in lung cancer tissues of several histological subtypes. Finally, the methylation of TBX2 subfamily members in the promoter region of NSCLC was significantly higher than that in normal tissues.
    Conclusion: Our research provided sufficient evidence that TBX2 subfamily might play an inhibitory role in malignancy progression of lung cancer, which is promising to shed light on discovering a novel reliable cancer marker for prognosis of lung cancer patients.
    Language English
    Publishing date 2024-02-27
    Publishing country United States
    Document type Journal Article
    ISSN 2730-6011
    ISSN (online) 2730-6011
    DOI 10.1007/s12672-024-00900-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Feasibility of utilising porous aggregates for carbon sequestration in concrete

    Mi, Renjie / Yu, Tao / Poon, C. S.

    Environmental Research. 2023 July, v. 228 p.115924-

    2023  

    Abstract: Carbon sequestration in concrete has attracted increasing research attention. CO₂ may be permanently stored in the cement paste of concrete by chemical reaction with the hydration products of cement, but this method leads to a significant reduction of ... ...

    Abstract Carbon sequestration in concrete has attracted increasing research attention. CO₂ may be permanently stored in the cement paste of concrete by chemical reaction with the hydration products of cement, but this method leads to a significant reduction of the pH value of the concrete pore solution and may thus put the steel reinforcement at risk of corrosion. This paper proposes a new method for carbon sequestration in concrete using the space in porous coarse aggregates; the method involves presoaking the porous aggregates in an alkaline slurry and then using them for CO₂ sequestration. The potential of utilising the space in the porous aggregates and the cations in the alkaline slurry is first discussed. An experimental study aiming to demonstrate the feasibility of the proposed method is then presented. The results show that CO₂ can be successfully sequestrated and fixed as CaCO₃ in the open pores of coarse coral aggregate presoaked in a Ca(OH)₂ slurry. The amount of CO₂ sequestration by concrete produced using the presoaked coral aggregate was around 20 kg/m³. Importantly, the proposed CO₂ sequestration method did not affect the strength development of the concrete or the pH value of the concrete pore solution.
    Keywords carbon dioxide ; carbon sequestration ; cement ; concrete ; corals ; corrosion ; pH ; presoaking ; research ; risk ; slurries ; steel ; Porous aggregates ; Open pores ; Alkaline slurry
    Language English
    Dates of publication 2023-07
    Publishing place Elsevier Inc.
    Document type Article ; Online
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2023.115924
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 726: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Bone marrow necrosis after treatment with blinatumomab for acute lymphoblastic leukemia: A case report.

    Mi, Ruihua / Chen, Lin / Wang, Lin / Wei, Xudong

    Asian journal of surgery

    2023  Volume 47, Issue 3, Page(s) 1449–1450

    MeSH term(s) Humans ; Bone Marrow ; Precursor Cell Lymphoblastic Leukemia-Lymphoma/drug therapy ; Antineoplastic Agents/adverse effects ; Antibodies, Bispecific/adverse effects ; Necrosis/chemically induced
    Chemical Substances blinatumomab (4FR53SIF3A) ; Antineoplastic Agents ; Antibodies, Bispecific
    Language English
    Publishing date 2023-12-07
    Publishing country Netherlands
    Document type Case Reports ; Letter
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2023.11.125
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2831: Show issues Location:
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  5. Article ; Online: Feasibility of utilising porous aggregates for carbon sequestration in concrete.

    Mi, Renjie / Yu, Tao / Poon, Chi Sun

    Environmental research

    2023  Volume 228, Page(s) 115924

    Abstract: Carbon sequestration in concrete has attracted increasing research attention. ... ...

    Abstract Carbon sequestration in concrete has attracted increasing research attention. CO
    MeSH term(s) Carbon Sequestration ; Carbon Dioxide ; Feasibility Studies ; Porosity ; Corrosion
    Chemical Substances Carbon Dioxide (142M471B3J)
    Language English
    Publishing date 2023-04-16
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 205699-9
    ISSN 1096-0953 ; 0013-9351
    ISSN (online) 1096-0953
    ISSN 0013-9351
    DOI 10.1016/j.envres.2023.115924
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 726: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: [Analysis of the clinical characteristics of acute myeloid leukemia related to the treatment of hematological and solid tumors].

    Jiao, Y / Jiang, Y H / Liu, B / Mi, R H / Bi, L J / Xu, Q X

    Zhonghua zhong liu za zhi [Chinese journal of oncology

    2024  Volume 46, Issue 1, Page(s) 86–95

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Humans ; Retrospective Studies ; Leukemia, Myeloid, Acute/drug therapy ; Leukemia, Myeloid, Acute/genetics ; Hematologic Neoplasms ; Mutation ; Hematology
    Language Chinese
    Publishing date 2024-01-05
    Publishing country China
    Document type English Abstract ; Journal Article
    ZDB-ID 603424-x
    ISSN 0253-3766
    ISSN 0253-3766
    DOI 10.3760/cma.j.cn112152-20231024-00249
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2277: Show issues Location:
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    Zs.MO 321: Show issues

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  7. Article ; Online: Postsynaptic β1 spectrin maintains Na

    Sert, Ozlem / Ding, Xiaoyun / Zhang, Chuansheng / Mi, Ruifa / Hoke, Ahmet / Rasband, Matthew N

    The Journal of physiology

    2024  Volume 602, Issue 6, Page(s) 1127–1145

    Abstract: Spectrins function together with actin as obligatory subunits of the submembranous cytoskeleton. Spectrins maintain cell shape, resist mechanical forces, and stabilize ion channel and transporter protein complexes through binding to scaffolding proteins. ...

    Abstract Spectrins function together with actin as obligatory subunits of the submembranous cytoskeleton. Spectrins maintain cell shape, resist mechanical forces, and stabilize ion channel and transporter protein complexes through binding to scaffolding proteins. Recently, pathogenic variants of SPTBN4 (β4 spectrin) were reported to cause both neuropathy and myopathy. Although the role of β4 spectrin in neurons is mostly understood, its function in skeletal muscle, another excitable tissue subject to large forces, is unknown. Here, using a muscle specific β4 spectrin conditional knockout mouse, we show that β4 spectrin does not contribute to muscle function. In addition, we show β4 spectrin is not present in muscle, indicating the previously reported myopathy associated with pathogenic SPTBN4 variants is neurogenic in origin. More broadly, we show that α2, β1 and β2 spectrins are found in skeletal muscle, with α2 and β1 spectrins being enriched at the postsynaptic neuromuscular junction (NMJ). Surprisingly, using muscle specific conditional knockout mice, we show that loss of α2 and β2 spectrins had no effect on muscle health, function or the enrichment of β1 spectrin at the NMJ. Muscle specific deletion of β1 spectrin also had no effect on muscle health, but, with increasing age, resulted in the loss of clustered NMJ Na
    MeSH term(s) Mice ; Animals ; Humans ; Spectrin/genetics ; Spectrin/analysis ; Spectrin/metabolism ; Actin Cytoskeleton/metabolism ; Neuromuscular Junction/metabolism ; Muscle, Skeletal/metabolism ; Muscular Diseases
    Chemical Substances Spectrin (12634-43-4)
    Language English
    Publishing date 2024-03-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 3115-x
    ISSN 1469-7793 ; 0022-3751
    ISSN (online) 1469-7793
    ISSN 0022-3751
    DOI 10.1113/JP285894
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    Uc I Zs.65: Show issues Location:
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  8. Article: Rhodium-catalyzed atroposelective access to trisubstituted olefins

    Zhu, Xiaohan / Mi, Ruijie / Yin, Jie / Wang, Fen / Li, Xingwei

    Chemical science

    2023  Volume 14, Issue 29, Page(s) 7999–8005

    Abstract: The atroposelective synthesis of axially chiral acyclic olefins remains a daunting challenge due to their relatively lower racemization barriers, especially for trisubstituted ones. In this work, atroposelective C-H olefination has been realized for ... ...

    Abstract The atroposelective synthesis of axially chiral acyclic olefins remains a daunting challenge due to their relatively lower racemization barriers, especially for trisubstituted ones. In this work, atroposelective C-H olefination has been realized for synthesis of open-chain trisubstituted olefins
    Language English
    Publishing date 2023-07-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2559110-1
    ISSN 2041-6539 ; 2041-6520
    ISSN (online) 2041-6539
    ISSN 2041-6520
    DOI 10.1039/d3sc02714g
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Stenotic geometry effects on airflow dynamics and respiration for central airway obstruction.

    Ding, Ming / Ning, Jing / Liu, Xiuyan / Mi, Runze / Cai, Yan

    Computer methods and programs in biomedicine

    2023  Volume 241, Page(s) 107760

    Abstract: Background and objective: The quantitative relationship between tracheal anatomy and ventilation function can be analyzed by using engineering-derived methods, including mathematical modeling and numerical simulations. In order to provide quantitative ... ...

    Abstract Background and objective: The quantitative relationship between tracheal anatomy and ventilation function can be analyzed by using engineering-derived methods, including mathematical modeling and numerical simulations. In order to provide quantitative functional evaluation for patients with tracheobronchial stenosis, we here propose an aerodynamics-based assessment method by applying computational fluid dynamics analysis on synthetic and patient-specific airway models.
    Methods: By using 3D reconstruction of tracheobronchial tree and computational fluid dynamics simulations, the aerodynamic environment from the stenotic central airway down to the 4th-6th bifurcation of the tracheobronchial tree is examined in both synthetic and patient-derived models. The effects of stenotic anatomy (the degree of stenosis, stenotic length and location) on the aerodynamic parameters, including pressure drop, area-average velocity, volume flow rate, wall shear stress and airflow resistance, are investigated on three-dimensional models of tracheobronchial tree.
    Results: The results from 36 synthetic models demonstrate that 70% constriction marks the onset of a precipitous decrease in airflow relative to a normal airway. The analyses of simulation results of 8 patient-specific models indicate that the Myer-Cotton stenosis grading system can be interpreted in terms of aerodynamics-derived description, such as flow resistance. The tracheal stenosis significantly influences the resistance of peripheral bronchi, especially for patients with severe stenosis.
    Conclusions: The present study forms a systematic framework for future development of more robust, bioengineering-informed evaluation methods for quantitative assessment of respiratory function of patients with central airway obstruction.
    MeSH term(s) Humans ; Constriction, Pathologic ; Respiration ; Computer Simulation ; Airway Obstruction ; Trachea ; Hydrodynamics
    Language English
    Publishing date 2023-08-09
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 632564-6
    ISSN 1872-7565 ; 0169-2607
    ISSN (online) 1872-7565
    ISSN 0169-2607
    DOI 10.1016/j.cmpb.2023.107760
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 521: Show issues Location:
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  10. Article: Journalists' Response and Reporting of Public Emergencies in the Era of Artificial Intelligence.

    Lian, Shaoying / Mi, Ruoyu / Tang, Runhua

    publication RETRACTED

    Applied bionics and biomechanics

    2022  Volume 2022, Page(s) 6574365

    Abstract: In order to improve the response ability of journalists to public emergencies, this study uses the computer simulation research method, based on Shannon's information theory and the basic theory of journalism and communication, constructs the general ... ...

    Abstract In order to improve the response ability of journalists to public emergencies, this study uses the computer simulation research method, based on Shannon's information theory and the basic theory of journalism and communication, constructs the general model of public emergencies based on the statistical results of big data, and constructs the irrational natural person game model of four types of news communication participants. In the simulation analysis, it is found that in the face of public emergencies, journalists, on the one hand, firmly implement the publicity caliber, strengthen the amount of creation, and improve the forwarding amount and approval amount of manuscripts under the artificial intelligence news system. On the other hand, they should achieve effective interaction with nonofficial news media such as we media, and the subjective news department should provide effective guidance and guidance to the media.
    Language English
    Publishing date 2022-01-22
    Publishing country Egypt
    Document type Journal Article ; Retracted Publication
    ZDB-ID 2179924-6
    ISSN 1754-2103 ; 1176-2322
    ISSN (online) 1754-2103
    ISSN 1176-2322
    DOI 10.1155/2022/6574365
    Database MEDical Literature Analysis and Retrieval System OnLINE

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