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Article ; Online: Sex body

Miao Li

Frontiers in Cell and Developmental Biology, Vol

A nest of protein mixture

2023 Volume 11

Abstract: During the pachytene stage in mammalian meiosis, the X and Y chromosomes remain largely unsynapsed outside the pseudoautosomal region, while autosomes are fully synapsed. Then, the sex chromosomes are compartmentalized into a “sex body” in the nucleus ... ...

Abstract	During the pachytene stage in mammalian meiosis, the X and Y chromosomes remain largely unsynapsed outside the pseudoautosomal region, while autosomes are fully synapsed. Then, the sex chromosomes are compartmentalized into a “sex body” in the nucleus and are subjected to meiotic sex chromosome inactivation (MSCI). For decades, the formation and functioning of the sex body and MSCI have been subjects worth exploring. Notably, a series of proteins have been reported to be located on the sex body area and inferred to play an essential role in MSCI; however, the proteins that are actually located in this area and how these proteins promote sex body formation and establish MSCI remain unclear. Collectively, the DNA damage response factors, downstream fanconi anemia proteins, and other canonical repressive histone modifications have been reported to be associated with the sex body. Here, this study reviews the factors located on the sex body area and tries to provide new insights into studying this mysterious domain.
Keywords	meiosis ; sex body ; MSCI ; DNA damage response ; epigenetic modifications ; Biology (General) ; QH301-705.5
Language	English
Publishing date	2023-04-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Financial Development, FDI and Economic Growth——A Research Based on the Mediation Effect Model

Miao Li

E3S Web of Conferences, Vol 251, p

2021 Volume 01087

Abstract: According to the mechanism of financial development, FDI and economic growth, this paper uses the individual fixed effects model and the mediation effect model of 31 provinces and cities in China from 2000 to 2019 to conduct empirical tests. The research ...

Abstract	According to the mechanism of financial development, FDI and economic growth, this paper uses the individual fixed effects model and the mediation effect model of 31 provinces and cities in China from 2000 to 2019 to conduct empirical tests. The research results show that from a national perspective, the improvement of China’s financial development level can significantly promote economic development. Secondly, from the perspective of regional samples, the financial development of the eastern provinces has a more significant impact on the economy, while the financial development of the central and western provinces has a limited impact on the economic development. Thirdly, from the perspective of FDI intermediary, financial development can significantly promote the improvement of economic level through FDI.
Keywords	Environmental sciences ; GE1-350
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	EDP Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Dynamics of Polar Resonances and Their Effects on Kozai–Lidov Mechanism

Miao Li / Shengping Gong

Applied Sciences, Vol 12, Iss 6530, p

2022 Volume 6530

Abstract: The research on highly inclined mean motion resonances (MMRs), even retrograde resonances, has drawn more attention in recent years. However, the dynamics of polar resonance with inclination

Abstract	The research on highly inclined mean motion resonances (MMRs), even retrograde resonances, has drawn more attention in recent years. However, the dynamics of polar resonance with inclination <math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>i</mi><mo>≈</mo><msup><mn>90</mn><mo>∘</mo></msup></mrow></semantics></math> have received much less attention. This paper systematically studies the dynamics of polar resonance and their effects on the Kozai–Lidov mechanism in the circular restricted three-body problem (CRTBP). The maps of dynamics are obtained through the numerical method and semi-analytical method, by mutual authenticating. We investigate the secular dynamics inside polar resonance. The phase-space portraits on the <math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>e</mi><mo>−</mo><mi>ω</mi></mrow></semantics></math> plane are plotted under exact polar resonance and considering libration amplitude of critical angle <math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mi>σ</mi></semantics></math> . Simultaneously, we investigate the evolution of 5000 particles in polar resonance by numerical integrations. We confirm that the <math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>e</mi><mo>−</mo><mi>ω</mi></mrow></semantics></math> portraits can entirely explain the results of numerical experiments, which demonstrate that the phase-space portraits on the <math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mi>e</mi><mo>−</mo><mi>ω</mi></mrow></semantics></math> plane obtained through the semi-analytical ...
Keywords	celestial mechanics ; Earth ; minor planets ; asteroids ; planets and satellites ; dynamical evolution and stability ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
Subject code	511
Language	English
Publishing date	2022-06-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The Application of Practical Clothing Design Method in the Teaching of Clothing Specialty

Miao Li / Rong Fu

Advances in Multimedia, Vol

2022 Volume 2022

Abstract: To improve the teaching practice effect of clothing major, this study applies the practical clothing design method to the teaching of clothing major to analyze the digital clothing design and establishes a convex quadratic conic programming model for a ... ...

Abstract	To improve the teaching practice effect of clothing major, this study applies the practical clothing design method to the teaching of clothing major to analyze the digital clothing design and establishes a convex quadratic conic programming model for a class of force optimization problems. Then, this study transforms the optimality condition of the problem into a new projection equation system, constructs a suitable constant coefficient matrix according to the characteristics of the equation system, and obtains an equivalent linear equation system. In addition, this study proposes a full Newton step projection algorithm to directly solve the convex quadratic conic programming. Through the results of the experimental research, it can be seen that the practical clothing design method has a good application in the teaching of clothing majors, and it can be applied in the practice of clothing teaching.
Keywords	Electronic computers. Computer science ; QA75.5-76.95
Subject code	510
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Square wave reference digital lock-in detection using non-orthogonal demodulation

Miao Li / Yue Sun / Zhen Liang / Shengzhao Zhang

Heliyon, Vol 9, Iss 1, Pp e12933- (2023)

2023

Abstract: Digital lock-in detection technique is commonly used to measure the amplitude and phase of a selected frequency signal. The technique which uses a square wave as the reference signal has an advantage of easier implementation and higher computational ... ...

Abstract	Digital lock-in detection technique is commonly used to measure the amplitude and phase of a selected frequency signal. The technique which uses a square wave as the reference signal has an advantage of easier implementation and higher computational efficiency compared to that uses a sine wave. However, one constraint for a square wave reference digital lock-in is that the sampling rate must be the integral multiple of 4 of all the signal frequencies. As the sampling clock may not always be able to set to the integral multiple of 4 of the signal frequencies, the constraint brings inconvenient for the implementation. Presented in this paper is a novel algorithm for square wave digital lock-in detection in which the sampling frequency doesn't have to meet the constraint. The algorithm allows frequency sweep measurements with a fixed sampling rate. For different relationships between the sampling rate and the signal frequency, different calculation equations are provided in this paper. Simulations and actual experiments show the feasibility of the proposed algorithm.
Keywords	Digital lock-in detection ; Square wave-reference ; Sampling rate ; Weak signal detection ; Non-orthogonal demodulation ; Science (General) ; Q1-390 ; Social sciences (General) ; H1-99
Subject code	535
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Effects of multi-domain intervention on intrinsic capacity in older adults

Xiaoyan Liao / Jun Shen / Miao Li

Experimental Gerontology, Vol 174, Iss , Pp 112112- (2023)

A systematic review of randomized controlled trials (RCTs)

2023

Abstract: Intrinsic capacity is central to the maintenance of function in older adults, and maintaining optimal intrinsic capacity is of great importance to promote healthy aging. The purpose of this systematic review and meta-analysis was to analyze the impact of ...

Abstract	Intrinsic capacity is central to the maintenance of function in older adults, and maintaining optimal intrinsic capacity is of great importance to promote healthy aging. The purpose of this systematic review and meta-analysis was to analyze the impact of multi-domain interventions on intrinsic capacity in older adults, intervention components, and potential interactions between components. A total of 6740 published articles were screened until August 2022, and the review included 25 randomized controlled trials that analyzed populations, interventions, control groups, and outcomes. The meta-analysis showed improvements in the primary outcome indicators in the intervention group compared to the control group. These included increased scores on the Mini-Mental State Examination as an indicator of cognitive function, decreased scores on the Geriatric Depression Scale (GDS-15) as an indicator of psychological ability and increased scores on the Short Physical Performance Battery (SPPB) as an indicator of physical performance, with only the SPPB indicator analyzed showing greater heterogeneity. Significant improvements were also seen in the secondary indicators Time-to-Walk Test (TUG), gait speed, Chair Stand Test (CST), grip strength values and BMI. There was insufficient data for the Mini Nutritional Assessment (MNA) as an indicator of vitality to conduct a meta-analysis. Studies were of moderate to high quality. The results of this review indicate that multi-domain interventions can maintain the level of intrinsic capacity in older adults and are equally effective in older adults with declining self-care abilities.
Keywords	Health aging ; Intrinsic capacity ; Multi-domain intervention ; Elderly ; Medicine ; R ; Biology (General) ; QH301-705.5
Subject code	796
Language	English
Publishing date	2023-04-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Hesitancy in the time of coronavirus

Ran Liu / Gabriel Miao Li

SSM: Population Health, Vol 15, Iss , Pp 100896- (2021)

Temporal, spatial, and sociodemographic variations in COVID-19 vaccine hesitancy

2021

Abstract: Leveraging nationally representative survey data on 443,680 respondents from January to March 2021, this study examines the temporal, spatial, and sociodemographic variations in COVID-19 vaccine hesitancy in the U.S. Findings reveal multidimensional ... ...

Abstract	Leveraging nationally representative survey data on 443,680 respondents from January to March 2021, this study examines the temporal, spatial, and sociodemographic variations in COVID-19 vaccine hesitancy in the U.S. Findings reveal multidimensional determinants of vaccination intentions involving confidence, complacency, and circumspection factors. Using descriptive analyses and multilevel mixed-effects regression models, we find persistent partisan divide across states and significant racial disparities, with Blacks more likely to develop vaccine hesitancy due to confidence and circumspection than Whites. Vaccine hesitancy among Blacks declines dramatically across time but varies little across states, indicating new directions to effectively address inequalities in vaccination. Results also show nuanced gender differences, with women more likely to develop hesitancy due to circumspection and men more likely to have hesitancy due to complacency. Moreover, we find important intersection between race, gender, and education that calls for efforts to adequately address the concerns of the most vulnerable and disadvantaged groups.
Keywords	Vaccine hesitancy ; COVID-19 ; Public health ; Inequality ; Race ; Public aspects of medicine ; RA1-1270 ; Social sciences (General) ; H1-99
Language	English
Publishing date	2021-09-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Educational Disparities in COVID-19 Prevention in China

Miao Li / Weidong Wang

International Journal of Environmental Research and Public Health, Vol 18, Iss 3383, p

The Role of Contextual Danger, Perceived Risk, and Interventional Context

2021 Volume 3383

Abstract: Despite the social disparities in COVID-19 infection, little is known about factors influencing social disparities in preventive behaviors during the pandemic. This study examined how educational disparities in mask-wearing, handwashing, and limiting ... ...

Abstract	Despite the social disparities in COVID-19 infection, little is known about factors influencing social disparities in preventive behaviors during the pandemic. This study examined how educational disparities in mask-wearing, handwashing, and limiting public outings might be contingent upon three factors: contextual cue of danger, perceived risk of local outbreak, and interventional context with different levels of intensity (i.e, Wuhan vs. other areas). Data were obtained from a telephone survey of 3327 adults, who were recruited through a random-digit-dial method to be representative of all cell phone users in China. Interviews were conducted from 28 April to 26 May 2020. Stratified multiple regression models showed that educational disparities in all three behaviors were only consistently observed among people exposed to context cues of danger, with an enhanced sense of risk of a local outbreak, or in areas other than Wuhan. College education seems to make a difference in handwashing regardless of contextual cues of danger or perception of risk. The findings suggested that, in the process of an epidemic, emerging threats in one’s immediate environment or raised awareness of risks are important conditions triggering educational disparities in prevention. However, effective public health interventions could potentially reduce such disparities.
Keywords	COVID-19 ; disparities ; distancing ; education ; fundamental cause ; mask-wearing ; Medicine ; R
Subject code	910
Language	English
Publishing date	2021-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Learning Optimal Fin-Ray Finger Design for Soft Grasping

Zhifeng Deng / Miao Li

Frontiers in Robotics and AI, Vol

2021 Volume 7

Abstract: The development of soft hands is an important progress to empower robotic grasping with passive compliance while greatly decreasing the complexity of control. Despite the advances during the past decades, it is still not clear how to design optimal hands ...

Abstract	The development of soft hands is an important progress to empower robotic grasping with passive compliance while greatly decreasing the complexity of control. Despite the advances during the past decades, it is still not clear how to design optimal hands or fingers given the task requirements. In this paper, we propose a framework to learn the optimal design parameter for a fin-ray finger in order to achieve stable grasping. First, the pseudo-kinematics of the soft finger is learned in simulation. Second, the task constraints are encoded as a combination of desired grasping force and the empirical grasping quality function in terms of winding number. Finally, the effectiveness of the proposed approach is validated with experiments in simulation and using real-world examples as well.
Keywords	soft hands ; robotic grasping ; soft finger design ; grasp quality ; grasp quality criterion ; Mechanical engineering and machinery ; TJ1-1570 ; Electronic computers. Computer science ; QA75.5-76.95
Subject code	670
Language	English
Publishing date	2021-02-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Ophthalmoplegia with a focal lesion in the interpeduncular fossa as the initial symptoms of multiple sclerosis

Kai Han / Yixuan Wang / Shasha Li / Tianshu Ye / Miao Li / Jie Wang

Journal of International Medical Research, Vol

3-year follow-up

2024 Volume 52

Abstract: The differential diagnosis of isolated ophthalmoplegia includes a range of pathologies. In this case, a 26-year-old man of Han nationality presented with ophthalmoplegia. Neuroimaging revealed an atypical focal lesion in the interpeduncular fossa. ... ...

Abstract	The differential diagnosis of isolated ophthalmoplegia includes a range of pathologies. In this case, a 26-year-old man of Han nationality presented with ophthalmoplegia. Neuroimaging revealed an atypical focal lesion in the interpeduncular fossa. Initial systemic workup indicated intracranial Mycobacterium tuberculosis infection, but there was no evidence to support a diagnosis of other autoimmune diseases (e.g., myasthenia gravis or multiple sclerosis). Neuroimaging follow-up over the next 3 years revealed progression from atypical solitary lesions to multifocal lesions in the white matter of the brain. Key immunological markers were observed in cerebrospinal fluid during follow-up, suggesting the evolution of multiple sclerosis. Ophthalmoplegia with a focal lesion in the interpeduncular fossa was an unusual set of symptoms indicating multiple sclerosis onset. The findings in this case suggest that M. tuberculosis infection is an important but overlooked factor involved in the pathogenesis of multiple sclerosis. Upon initial detection, atypical lesions should receive sufficient attention and patients should undergo systematic screening to identify M. tuberculosis infection and its associated immunological abnormalities.
Keywords	Medicine (General) ; R5-920
Subject code	616
Language	English
Publishing date	2024-01-01T00:00:00Z
Publisher	SAGE Publishing
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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